TW201536253A - Severity of obstructive sleep apnea analyzer and analysis thereof - Google Patents

Abstract

An analysis of severity of Obstructive Sleep Apnea is implemented using a band-pass filter to filter a vibration signal from a user and to generate a filter signal, and a processor to quantify the filter signal to find the Burst event after apnea event or hypopnea event, so as to permit analysis of severity of Obstructive Sleep Apnea.

Description

Obstructive sleep breathing suspension severity measuring device and method

The invention relates to a sleep breathing suspension severity measuring device and method, in particular to an obstructive sleep breathing suspension which can be analyzed and analyzed by an upper respiratory tract vibration signal for obstructive sleep breathing (OSA). Degree measuring device and method.

Sleep Apnea is a sleep disorder in which breathing stops during sleep. Breathing disorders during sleep can be divided into no-breathing (Apnea) and hypopnea (Hypopnea). No breathing is the flow of mouth and nose stops flowing for more than ten seconds. Hypnea is more than 50% of ventilation for more than 10 seconds or blood oxygenation. The saturation (SaO ₂ ) is reduced by at least 3%.

At present, the examination method for sleep breathing is polysomnography (PSG), which mainly monitors brain wave, electro-oculogram, and electromyogram to determine sleep stage, monitor mouth and nasal airflow when the test subject sleeps. In order to obtain the dynamics and respiratory activity of the chest and abdomen, and with a pulse oximeter to monitor changes in blood oxygen concentration. However, the test subject must have many sensors attached to the polysomnography measurement, which may cause discomfort to the test subject and reduce the willingness of the test subject to accept the measurement.

Therefore, the object of the present invention is to provide a The obstructive sleep apnea severity measuring device and method for assessing the severity of obstructive sleep apnea by the vibration signal of the respiratory tract.

Thus, the obstructive sleep breathing suspension severity of the present invention The measuring device comprises a sensing module, a filtering module, a processing module and an output module. The sensing module obtains a vibration sensing signal of the upper respiratory tract of the test subject during a sleep period; the filtering module performs band pass filtering on the vibration sensing signal to obtain a band pass signal; the processing module is configured according to the The bandpass signal quantification represents the violent vibration generated after the end of the respiratory arrest event or the hypopnea event, and the severity of the obstructive sleep apnea is evaluated according to the number thereof; the output module outputs the processing result of the processing module.

Preferably, the processing module finds the band pass signal at a time. a signal of a breath suspension or hypopnea below a first threshold value, and a signal after the signal of the suspension or hypopnea is judged whether there is a severe vibration signal greater than a second threshold, and the The second threshold is greater than the first threshold, and if so, the severe vibration signal is indicated as a severe vibration indicator.

Preferably, the processing module first performs a pre-processing procedure, The pre-processing program locates a plurality of peaks according to the band-pass signal, averages the peaks to obtain the first threshold, and averages a plurality of local peaks exceeding the first threshold to obtain the second threshold.

Preferably, the processing module completes all of the sleep period After the signal analysis, the number of all the severe vibration indicators is accumulated to obtain an accumulated value, and the accumulated value is divided by the sleep period of the person to be tested to obtain a sleep breathing abort severity index.

Preferably, the bandpass frequency of the filter module ranges from 50 to 100 Hz, and the range can be adjusted according to different sensing devices.

The method for measuring the severity of obstructive sleep breathing in the present invention comprises the steps of: (a) obtaining a vibration sensing signal of a subject's upper respiratory tract during a sleep period; (b) performing the vibration sensing signal Bandpass filtering results in a bandpass signal; (c) finding a signal for a pause or hypopnea that is below a first threshold for a time interval and a signal to suspend or ventilate the breath The subsequent signal determines whether there is a severe vibration signal greater than a second threshold, and the second threshold is greater than the first threshold, and if so, the severe vibration signal is marked as a severe vibration indicator; and (d The result of the processing of step (c) is output.

Preferably, between step (b) and step (c), the method further comprises: positioning a plurality of peaks according to the band pass signal, averaging the peak values to obtain the first threshold value, and exceeding the A plurality of local peaks of the first threshold are averaged to obtain the second threshold.

Preferably, the step (c) further comprises: after completing all the signal analysis during the sleep period, accumulating the number of all the severe vibration indicators to obtain an accumulated value, and dividing the accumulated value by the sleep period of the test subject In order to get a sleep breathing suspension severity index.

The function of the obstructive sleep breathing suspension severity measuring device and method of the present invention is that the vibration sensing signal obtained by the test subject is bandpassed. After filtering, distinguishing the breathing stop caused by the upper airway obstruction by determining the lower threshold value in the set time interval, and determining the second threshold value higher than the first threshold value to distinguish whether to breathe by force The resulting violent vibration is generated. Therefore, in addition to the effective judgment of whether or not the snoring is generated, the severity of the apnea event may be evaluated according to the frequency of occurrence of the apnea event during the entire sleep period of the subject.

100‧‧‧ Obstructive sleep breathing suspension severity measuring device

11‧‧‧Filter module

10‧‧‧Processing module

15‧‧‧Output module

12‧‧‧Amplification circuit

13‧‧‧ Analog Digital Converter

14‧‧‧Microprocessor

2‧‧‧recording module

3‧‧‧Sensing module

201~205‧‧‧Steps

301~308‧‧‧Steps

501, 502‧‧ events

Other features and advantages of the present invention will be apparent from the embodiments of the present invention, wherein: FIG. 1 is a system diagram illustrating a preferred embodiment of the obstructive sleep apnea severity measuring apparatus of the present invention; 2 is a flow chart illustrating a pre-processing procedure of the method for measuring the severity of obstructive sleep breathing in the present invention; FIG. 3 is a flow chart illustrating a preferred embodiment of the method for measuring the severity of obstructive sleep breathing in the present invention. .

Referring to FIG. 1 , in the preferred embodiment of the present invention, the obstructive sleep apnea severity measuring device 100 includes a sensing module 3 , a recording module 2 , a filtering module 11 , a processing module 10 , and An output module 15; the processing module 10 has an amplifying circuit 12, an analog digital converter 13 and a microprocessor 14.

In this embodiment, the sensing module 3 is a piezoelectric detector placed on the upper airway of the subject 5 to measure the snoring (Piezo Snore) Sensor), in other embodiments, the vibration sound wave signal of the microphone amount can also be used instead; the band pass frequency of the filter module 11 ranges from 50 to 100 Hz, and the background noise can be filtered by the background noise 60 Hz. . The output module 15 can be a display device, a printing device or other type of prompting device.

Method for measuring the severity of obstructive sleep breathing in the present invention The method includes the following steps: the sensing module 3 obtains a vibration sensing signal of the upper respiratory tract of the subject 5 during a sleep period (step 201); and the filtering module 11 performs band-pass filtering on the vibration sensing signal. A band pass signal (step 202); the processing module 10 amplifies the band pass signal by the amplifying circuit 12 and converts it into a digital signal by the analog bit converter 13.

The design of the present invention is based on the type of snoring including breathing suspension (apnea) event 501 and hypopnea event 502 are observed, and the aforementioned events 501, 502 end up with a sharp and continuous burst of vibration, which is due to the patient's prolonged upper airway obstruction. No oxygen can be absorbed, so the patient will inhale more. When the upper airway obstruction disappears, it will cause severe vibrations due to excessive force inhalation. Since this violent vibration occurs after the end of the breath-stop event 501 and the low-breath event 502, the continuous vibration after the pause of the breath is regarded as the occurrence of a violent vibration event.

See Figure 2 for the purpose of distinguishing between no breathing and intense and continuous vibration The microprocessor 14 must first perform a pre-processing procedure for locating a plurality of peaks based on the bandpass signal (step 203), averaging the peaks to obtain a first threshold (step 204). And will exceed a first threshold A plurality of local peaks are averaged to obtain the second threshold (step 205) and the second threshold will be greater than the first threshold.

Referring to Figure 3, during the analysis, the bandpass signal is input (step 301), the microprocessor 14 finds a signal of a breath suspension or hypopnea below a first threshold value (step 302) for the band pass signal during a time interval (eg, 10 seconds), and the breathing The signal after the signal of suspension or hypopnea determines whether there is a severe vibration signal greater than a second threshold (step 303)? If so, the severe vibration signal is indicated as a severe vibration indicator (step 304); all signal analysis during the sleep period is completed (step 305)? If so, the amount of all the severe vibration indicators is accumulated to obtain an accumulated value (step 306), and the accumulated value is divided by the sleep period of the person to be tested to obtain a sleep breathing abort severity index (step 307), and finally, by output The module 15 outputs a sleep breathing abort severity index (step 308).

In addition to the aforementioned methods, it is also possible to use the slope change to judge Break the violent vibration (Burst) indicator.

In summary, the obstructive sleep breathing of the present invention is severely interrupted. The effect of the degree measuring device 100 and the method is that the vibration sensing signal obtained by the subject 5 is filtered by the filtering module 11 and then determined by the microprocessor 14 to be lower than the first threshold in the time interval. The method distinguishes the breathing suspension caused by the upper airway obstruction, and the judgment manner of setting the second threshold value higher than the first threshold value to distinguish whether the severe vibration is caused by the forced breathing, and therefore, in addition to the effective determination of whether the breathing is suspended or not, In addition to the occurrence, the severity of the snoring event during the entire sleep period of the test subject 5 can also be evaluated, so that the object of the present invention can be achieved.

The above is only the preferred embodiment of the present invention, and the scope of the present invention is not limited thereto, that is, the simple equivalent changes and modifications made by the patent application scope and patent specification content of the present invention, All remain within the scope of the invention patent.

100‧‧‧ Obstructive sleep breathing suspension severity measuring device

10‧‧‧Processing module

11‧‧‧Filter module

12‧‧‧Amplification circuit

13‧‧‧ Analog Digital Converter

14‧‧‧Microprocessor

15‧‧‧Output module

2‧‧‧recording module

3‧‧‧Sensing module

5‧‧‧Users

501, 502‧‧ events

Claims (9)

An obstructive sleep breathing suspension severity measuring device comprises: a sensing module, obtaining a vibration sensing signal of a upper respiratory tract of a person to be tested during a sleep period; and a filtering module for sensing the vibration The signal is bandpass filtered to obtain a bandpass signal; a processing module quantizes the severe vibration generated after the end of the respiratory suspension event or the hypopnea event according to the bandpass signal, and according to the number thereof, the severity of the obstructive sleep breathing suspension Evaluation; and an output module that outputs the processing result of the processing module. The obstructive sleep apnea suspension severity measuring apparatus according to claim 1, wherein the processing module quantizes the channel to find a breath that is lower than a first threshold value in a time interval. The signal of suspension or hypopnea, and the signal after the signal of the suspension or hypopnea is judged whether there is a severe vibration signal greater than a second threshold, and the second threshold is greater than the first threshold, if any , the severe vibration signal is marked as a severe vibration indicator. The obstructive sleep apnea suspension severity measuring device according to claim 2, wherein the processing module first performs a pre-processing procedure, wherein the pre-processing program locates a plurality of peaks according to the band-pass signal, and the same The peak averaging obtains the first threshold and averages a plurality of local peaks that exceed the first threshold to obtain the second threshold. The obstructive sleep apnea suspension severity measuring device of claim 3, wherein the processing module completes all signal points during the sleep period After the analysis, the number of all the severe vibration indicators is accumulated to obtain a cumulative value, and the accumulated value is divided by the sleep period of the person to be tested to obtain a sleep breathing abort severity index. The obstructive sleep apnea suspension severity measuring device according to claim 4, wherein the filter module has a band pass frequency ranging from 50 to 100 Hz. A method for measuring the severity of obstructive sleep breathing, comprising the steps of: (a) obtaining a vibration sensing signal of a subject's upper respiratory tract during a sleep period; (b) performing the vibration sensing signal Bandpass filtering results in a bandpass signal; (c) finding a signal for a pause or hypopnea that is below a first threshold for a time interval and a signal to suspend or ventilate the breath The subsequent signal determines whether there is a severe vibration signal greater than a second threshold, and the second threshold is greater than the first threshold, and if so, the severe vibration signal is marked as a severe vibration indicator; and (d The result of the processing of step (c) is output. The method for measuring the severity of obstructive sleep apnea suspension according to claim 6, further comprising the step of: locating a plurality of peaks according to the band pass signal between the steps (b) and (c), The peak averaging obtains the first threshold and averages a plurality of local peaks that exceed the first threshold to obtain the second threshold. The amount of obstructive sleep apnea discontinuity as described in claim 6 or 7 The measuring method, wherein the step (c) further comprises: after completing all the signal analysis during the sleep period, accumulating the number of all the severe vibration indicators to obtain an accumulated value, and dividing the accumulated value by the sleep of the test subject During the period to get a sleep breathing stop serious index. The obstructive sleep apnea suspension severity measuring method according to claim 8, wherein the band pass filtering frequency ranges from 50 to 100 Hz.