TW201414468A - Ptp package - Google Patents

Ptp package Download PDF

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Publication number
TW201414468A
TW201414468A TW102136432A TW102136432A TW201414468A TW 201414468 A TW201414468 A TW 201414468A TW 102136432 A TW102136432 A TW 102136432A TW 102136432 A TW102136432 A TW 102136432A TW 201414468 A TW201414468 A TW 201414468A
Authority
TW
Taiwan
Prior art keywords
ptp package
top surface
ptp
side wall
shape
Prior art date
Application number
TW102136432A
Other languages
Chinese (zh)
Inventor
Tomohiro Yoshita
Yusuke Hirano
Fumi Izumi
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of TW201414468A publication Critical patent/TW201414468A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035Blister-type containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments

Abstract

The purpose of the present invention is to improve the press-through characteristics when extracting a packaged object from a PTP package. A PTP package (1) is provided with the following: a PTP sheet (3) that has a projecting pocket section (20) which protrudes from a sheet surface side and that is capable of accommodating a pharmaceutical preparation in the pocket section (20); and a lid member (4) which is adhered to the back surface of the PTP sheet (3) so as to seal the pocket section (20). The pocket section (20) comprises side walls (21) that stand upright on the sheet surface side, and a top surface (22) formed at the ends of the side walls (21) at the opposite end from the lid member (4). The top surface (22) is inclined relative to the portion of the lid member (4) that is surrounded by the side walls (21).

Description

PTP包裝體 PTP package

本發明係關於一種PTP包裝體,尤其係關於一種自PTP包裝體擠出片劑或膠囊劑等被包裝物時之擠壓性(易擠出性)獲得提升的PTP包裝體。 The present invention relates to a PTP package, and more particularly to a PTP package in which extrusion (extrusion) is improved when a package such as a tablet or a capsule is extruded from a PTP package.

自先前以來,於片劑或膠囊劑等包裝,廣泛地使用擠壓包裝(PTP:Press Through Package)包裝體。 A package of PTP (Press Through Package) has been widely used for packaging such as tablets or capsules.

PTP包裝體係由下述構成所形成的包裝體:在將被包裝物收容於形成在PTP片材之袋部後,用容易擠破之蓋材進行密封的構成。 The PTP packaging system has a structure in which a package is placed in a bag portion formed in a PTP sheet, and then sealed with a cover material that is easily crushed.

於自PTP包裝體擠出被包裝物時,藉由使圓弧狀之袋部頂面向蓋材側凹陷,被包裝物受到擠壓,並擠破蓋材而被擠出。 When the packaged object is extruded from the PTP package, the packaged object is pressed by the arc-shaped pocket top facing the cover material side, and the cover material is squeezed and extruded.

關於此種PTP包裝體之形狀,例如已知有如專利文獻1者。 Regarding the shape of such a PTP package, for example, Patent Document 1 is known.

如圖11所示,專利文獻1記載之PTP包裝體101係由具備有收容部120(用以收容醫藥品製劑102)之片狀容器103與將收容部120密封之蓋材104構成。 As shown in FIG. 11, the PTP package 101 described in Patent Document 1 is composed of a sheet container 103 including a housing portion 120 (for housing the pharmaceutical preparation 102) and a lid member 104 for sealing the housing portion 120.

收容部120之側壁121相對於蓋材104向一方向傾斜地豎設,形成為由收容部120及蓋材104包圍之空間的剖面形狀略呈菱形。 The side wall 121 of the accommodating portion 120 is erected obliquely with respect to the lid member 104 in a direction, and the cross-sectional shape of the space surrounded by the accommodating portion 120 and the lid member 104 is slightly rhombic.

藉由以此方式使收容醫藥品製劑102之空間的剖面形狀略呈菱形,於將收容部120之頂面122向蓋材104側擠壓而取出醫藥品製劑102時,可使 收容部120之歪倒、變形、壓縮較容易而提升蓋材104之開封性。 By making the cross-sectional shape of the space for accommodating the pharmaceutical preparation 102 slightly rhombic in this manner, when the top surface 122 of the accommodating portion 120 is pressed toward the lid member 104 side, the pharmaceutical preparation 102 can be taken out. The accommodating portion 120 is easily collapsed, deformed, and compressed to improve the opening property of the cover member 104.

[專利文獻1]日本特開2008-68873號公報 [Patent Document 1] Japanese Patent Laid-Open Publication No. 2008-68873

然而,如專利文獻1此類之PTP包裝體101,雖然藉由使收容醫藥品製劑102之收容部120的側壁121相對於蓋材104傾斜地豎設,而使收容部120之變形較容易從而提升PTP包裝體101之開封性,但是對於收容部120之頂面122的形狀並未特別考慮。因此,期望一種對容器頂面之形狀下工夫,而使手指容易抵壓,且使取出醫藥品製劑時之擠壓性進一步提升之PTP包裝體。 However, in the PTP package 101 of the patent document 1, the side wall 121 of the accommodating portion 120 accommodating the pharmaceutical preparation 102 is erected obliquely with respect to the lid member 104, so that the deformation of the accommodating portion 120 is facilitated and improved. The PTP package 101 has an unsealing property, but the shape of the top surface 122 of the accommodating portion 120 is not particularly considered. Therefore, it is desirable to have a PTP package which is easy to press against the shape of the top surface of the container and which further improves the squeezing property when the pharmaceutical preparation is taken out.

又,對於所有人,尤其是常常利用醫藥品製劑之高齡者而言,期望一種可容易地自包裝體取出醫藥品製劑之具備通用化設計的PTP包裝體。 Further, for all people, especially elderly people who often use pharmaceutical preparations, a PTP package having a general design that can easily take out a pharmaceutical preparation from a package is desired.

本發明係鑒於上述課題而完成者,本發明之目的在於提供一種作為通用化設計使自PTP包裝體取出被包裝物時之擠壓性提升的PTP包裝體。 The present invention has been made in view of the above problems, and an object of the present invention is to provide a PTP package which is improved in squeezability when a packaged article is taken out from a PTP package as a general-purpose design.

本發明之另一目的在於提供一種具備有手指容易抵壓之形狀的PTP包裝體。 Another object of the present invention is to provide a PTP package having a shape in which a finger is easily pressed.

上述課題係藉由如下方式解決:根據本發明之PTP包裝體,具備:具有向片材表面側突出之凸狀袋部且可將被包裝物收容於該袋部的PTP片材、與以密封上述袋部之方式貼合於該PTP片材背面的蓋材,上述袋部係由豎設於上述片材表面側之側壁、與形成於該側壁之上述蓋材相反側之端部的頂面構成,該頂面相對於上述蓋材中之由上述側壁包圍之部分傾斜。 The above-mentioned problem is solved by the PTP package according to the present invention comprising: a PTP sheet having a convex pocket portion protruding toward the surface side of the sheet and capable of accommodating the packaged object in the pocket portion, and sealing The bag portion is bonded to the lid member on the back surface of the PTP sheet, and the bag portion is formed on a side surface of the side surface of the sheet surface and a top surface of the end portion of the side wall opposite to the lid member. The top surface is inclined with respect to a portion of the cover material surrounded by the side wall.

如此,由於袋部之頂面相對於蓋材中之由側壁包圍之部分傾斜,故而於將袋部之頂面向蓋材側擠出時,擠出力容易集中於袋部之向蓋 材側傾斜之最近的部分,從而可使袋部容易凹陷。藉由使袋部容易凹陷,收容於袋部之被包裝物變得容易擠破蓋材而被擠出。 In this way, since the top surface of the bag portion is inclined with respect to the portion surrounded by the side wall in the lid member, when the top portion of the bag portion is pressed toward the lid member side, the extrusion force is easily concentrated on the lid portion of the bag portion. The nearest part of the material side is inclined so that the pocket portion can be easily recessed. By easily sagged the bag portion, the packaged article accommodated in the bag portion is easily squeezed out of the lid member and extruded.

亦即,可提供作為能提升自PTP包裝體取出被包裝物時之擠壓性且具備通用化設計的PTP包裝體。 That is, it is possible to provide a PTP package which has a squeezing property when the packaged article is taken out from the PTP package and has a generalized design.

此時,較佳為上述側壁以位於上述袋部內側之方式,相對於上述蓋材中之由上述側壁包圍之部分傾斜。 In this case, it is preferable that the side wall is inclined with respect to a portion surrounded by the side wall of the cover member so as to be located inside the bag portion.

由於係以此方式構成,故而於將袋部之頂面向蓋材側擠出時,袋部之側壁變得容易倒向內側,從而可使袋部更加容易凹陷。 Since it is configured in this manner, when the top of the bag portion is pressed toward the cover material side, the side wall of the bag portion is easily inverted to the inner side, so that the bag portion can be more easily recessed.

亦即,可進一步容易地自PTP包裝體取出被包裝物。 That is, the packaged article can be further easily taken out from the PTP package.

此時,上述側壁較佳為具備該側壁中之形成為最低的第1部分、與相對於該第1部分隔著上述頂面而位於相反側且形成為高於上述第1部分的第2部分。 In this case, the side wall preferably includes a first portion which is formed to be the lowest in the side wall, and a second portion which is located on the opposite side to the first portion via the top surface and which is formed to be higher than the first portion. .

由於係以此方式構成,故於將袋部之頂面擠出時,擠出力容易集中於側壁中之形成為最低的第1部分,從而可使袋部容易凹陷。亦即,可進一步容易地自PTP包裝體取出被包裝物。 Since it is comprised in this way, when the top surface of the bag part is extruded, the extrusion force tends to concentrate on the 1st part which formed the minimum in a side wall, and it can make it easy to dent. That is, the packaged article can be further easily taken out from the PTP package.

此時,較佳為上述側壁中之上述第2部分形成為最高。 In this case, it is preferable that the second portion of the side wall is formed to be the highest.

如此,由於相對於形成為最低之第1部分隔著頂面而位於相反側的第2部分形成為最高,故於將袋部之頂面擠出時,擠出力容易變得更加易於集中在側壁中之第1部分,從而可使袋部容易凹陷。 In this manner, since the second portion located on the opposite side with respect to the first portion formed to be the lowest portion is formed to be the highest, when the top surface of the bag portion is extruded, the extrusion force is more likely to be concentrated on the side wall. In the first part, the bag portion is easily recessed.

此時,較佳為上述頂面係由大致平板狀構成。 In this case, it is preferable that the top surface is formed in a substantially flat shape.

如此,由於頂面係由平板狀構成,故可提供具備容易將手指抵壓於袋部頂面之形狀的PTP包裝體。 As described above, since the top surface is formed in a flat shape, it is possible to provide a PTP package having a shape in which the finger is easily pressed against the top surface of the bag portion.

此時,較佳為上述頂面係由選自包含大致圓形、大致橢圓形及大致多角形狀之群中的任一種形狀構成。 In this case, it is preferable that the top surface is formed of any one selected from the group consisting of a substantially circular shape, a substantially elliptical shape, and a substantially polygonal shape.

由於係以此方式構成,故可提供能夠根據醫藥品製劑之形狀而適當變 更袋部頂面之形狀的PTP包裝體。 Since it is constituted in this manner, it can be provided to be appropriately changed according to the shape of the pharmaceutical preparation. A PTP package in the shape of the top of the bag.

又,可提供能夠根據使用者之意向適當變更手指所抵壓之袋部頂面之形狀,且可容易地取出被包裝物的PTP包裝體。 Further, it is possible to provide a PTP package in which the shape of the top surface of the bag portion which is pressed by the finger can be appropriately changed according to the user's intention, and the packaged article can be easily taken out.

此時,上述被包裝物較佳為醫藥品製劑。 In this case, the packaged product is preferably a pharmaceutical preparation.

如此,於被包裝物為醫藥品製劑時,常常利用醫藥品製劑之高齡者可容易地自PTP包裝體取出醫藥品製劑,因此,可提供作為具備有通用化設計之PTP包裝體。 As described above, when the packaged product is a pharmaceutical preparation, the elderly person who uses the pharmaceutical preparation can easily take out the pharmaceutical preparation from the PTP package, and therefore, it can be provided as a PTP package having a generalized design.

此時,上述頂面與上述蓋材中之由上述側壁包圍之部分所構成的角度θ較佳為5°≦θ≦70°。 At this time, the angle θ between the top surface and the portion of the lid member surrounded by the side wall is preferably 5° ≦ θ ≦ 70°.

如此,由於角度θ為5°≦θ≦70°,故可形成考慮使用者利用手指抵壓袋部頂面時之操作性、及自PTP包裝體取出被包裝物時之擠壓性,而經角度設定的PTP包裝體。 Thus, since the angle θ is 5° ≦ θ ≦ 70°, it is possible to form the operability in consideration of the user's use of the finger to press the top surface of the bag portion, and the squeezing property when the packaged object is taken out from the PTP package body. Angle set PTP package.

又,藉由以5°為下限值而設定角度θ,可實現自PTP包裝體取出被包裝物時之擠壓性的提升。 Further, by setting the angle θ with a lower limit of 5°, it is possible to improve the squeezing property when the packaged article is taken out from the PTP package.

進而,藉由以70°為上限值而設定角度θ,可實現考慮到能夠收納醫藥品製劑之範圍之PTP包裝體之製造。 Further, by setting the angle θ with an upper limit of 70°, it is possible to realize the production of a PTP package in consideration of the range in which the pharmaceutical preparation can be accommodated.

此時,上述θ更佳為5°≦θ≦20°。 At this time, the above θ is more preferably 5° ≦ θ ≦ 20°.

如此,由於角度θ為5°≦θ≦20°,故藉由以20°為上限值而設定角度θ,可將PTP包裝體之頂面設為手指更加容易抵壓之形狀。 As described above, since the angle θ is 5° ≦ θ ≦ 20°, the top surface of the PTP package can be set to a shape in which the finger is more easily pressed by setting the angle θ with the upper limit of 20°.

此時,上述θ更佳為10°≦θ≦15°。 At this time, the above θ is more preferably 10° ≦ θ ≦ 15°.

如此,由於角度θ為10°≦θ≦15°,故藉由以10°為下限值設定角度θ,可更加提升自PTP包裝體取出被包裝物時之擠壓性。又,藉由以15°為上限值設定角度θ,可使用原有設備而實現考慮到製造成本之PTP包裝體之製造。 As described above, since the angle θ is 10° ≦ θ ≦ 15°, by setting the angle θ by 10° as the lower limit value, the squeezing property when the packaged article is taken out from the PTP package can be further improved. Moreover, by setting the angle θ with an upper limit of 15°, it is possible to realize the manufacture of a PTP package in consideration of the manufacturing cost using the original equipment.

根據本發明之PTP包裝體,袋部之頂面相對於蓋材中之由 側壁包圍之部分傾斜,故於將袋部之頂面向蓋材側擠出時,擠出力容易集中於袋部之向蓋材側傾斜之最近的部分,從而可使袋部容易凹陷。藉由使袋部容易凹陷,收容於袋部之被包裝物變得容易擠破蓋材而被擠出。 According to the PTP package of the present invention, the top surface of the bag portion is opposite to the cover material When the portion surrounded by the side wall is inclined, when the top of the bag portion is pressed toward the lid member side, the extrusion force tends to concentrate on the portion of the bag portion that is inclined toward the lid member side, so that the bag portion can be easily recessed. By easily sagged the bag portion, the packaged article accommodated in the bag portion is easily squeezed out of the lid member and extruded.

亦即,可提供作為能提升自PTP包裝體取出被包裝物時之擠壓性且具備通用化設計的PTP包裝體。 That is, it is possible to provide a PTP package which has a squeezing property when the packaged article is taken out from the PTP package and has a generalized design.

又,由於PTP包裝體之頂面係由平板狀構成,故可提供具備容易將手指抵壓於頂面之形狀的PTP包裝體。 Further, since the top surface of the PTP package is formed in a flat shape, it is possible to provide a PTP package having a shape in which a finger is easily pressed against the top surface.

1‧‧‧PTP包裝體 1‧‧‧PTP package

2‧‧‧醫藥品製劑 2‧‧‧Pharmaceutical preparations

3‧‧‧PTP片材 3‧‧‧PTP sheet

4‧‧‧蓋材 4‧‧‧Cleaning

10‧‧‧片材基板部 10‧‧‧Sheet substrate unit

11‧‧‧把手部 11‧‧‧Hands

20‧‧‧袋部 20‧‧‧ bag department

21‧‧‧側壁 21‧‧‧ side wall

21a‧‧‧第1部分 21a‧‧‧Part 1

21b‧‧‧第2部分 21b‧‧‧Part 2

22‧‧‧頂面 22‧‧‧ top surface

22a‧‧‧中心 22a‧‧ Center

23a‧‧‧中心軸 23a‧‧‧Center axis

23b‧‧‧中心軸 23b‧‧‧Center axis

24‧‧‧角部 24‧‧‧ corner

25‧‧‧角部 25‧‧‧ corner

101‧‧‧PTP包裝體 101‧‧‧PTP package

102‧‧‧醫藥品製劑 102‧‧‧Pharmaceutical preparations

103‧‧‧片狀容器 103‧‧‧Flake container

104‧‧‧蓋材 104‧‧‧Cleaning

120‧‧‧收容部 120‧‧‧Receiving Department

121‧‧‧側壁 121‧‧‧ side wall

122‧‧‧頂面 122‧‧‧ top surface

α‧‧‧接地角度 Α‧‧‧ grounding angle

θ‧‧‧傾斜角度 Θ‧‧‧ tilt angle

圖1係本發明之PTP包裝體的立體圖。 Figure 1 is a perspective view of a PTP package of the present invention.

圖2係圖1之PTP包裝體A-A剖面,且係主要部分放大剖面圖。 Fig. 2 is a cross-sectional view showing the PTP package A-A of Fig. 1 and showing a main portion thereof.

圖3係表示本發明實施例之擠出荷重試驗結果的圖表。 Fig. 3 is a graph showing the results of an extrusion load test of an embodiment of the present invention.

圖4係本發明之PTP包裝體的前視圖。 Figure 4 is a front elevational view of the PTP package of the present invention.

圖5係本發明之PTP包裝體的右側視圖。 Figure 5 is a right side view of the PTP package of the present invention.

圖6係本發明之PTP包裝體的左側視圖。 Figure 6 is a left side view of the PTP package of the present invention.

圖7係本發明之PTP包裝體的俯視圖。 Figure 7 is a plan view of the PTP package of the present invention.

圖8係本發明之PTP包裝體的仰視圖。 Figure 8 is a bottom plan view of the PTP package of the present invention.

圖9係圖1之PTP包裝體A-A剖面圖。 Figure 9 is a cross-sectional view of the PTP package A-A of Figure 1.

圖10(a)係圖1之PTP包裝體B-B剖面圖,圖10(b)係圖10(a)之放大圖。 Figure 10 (a) is a cross-sectional view of the PTP package B-B of Figure 1, and Figure 10 (b) is an enlarged view of Figure 10 (a).

圖11係習知例之PTP包裝體的說明圖。 Fig. 11 is an explanatory view of a PTP package of a conventional example.

以下,參照圖對本發明之實施形態進行說明。再者,以下所 說明之構件、配置等並非限定本發明者,可按照本發明之主旨進行各種改變。 Hereinafter, embodiments of the present invention will be described with reference to the drawings. Furthermore, the following The members, the arrangement, and the like described are not intended to limit the invention, and various modifications can be made in accordance with the gist of the invention.

圖1係本發明之PTP包裝體的立體圖。圖2係圖1之PTP包裝體A-A剖面,且係主要部分放大剖面圖。圖3係表示本發明實施例之擠出荷重試驗結果的圖表。圖4係本發明之PTP包裝體的前視圖。圖5係本發明之PTP包裝體的右側視圖。圖6係本發明之PTP包裝體的左側視圖。圖7係本發明之PTP包裝體的俯視圖。圖8係本發明之PTP包裝體的仰視圖。圖9係圖1之PTP包裝體A-A剖面圖。圖10(a)係圖1之PTP包裝體B-B剖面圖,(b)係(a)之放大圖。圖11係習知例之PTP包裝體的說明圖。 Figure 1 is a perspective view of a PTP package of the present invention. Fig. 2 is a cross-sectional view showing the PTP package A-A of Fig. 1 and showing a main portion thereof. Fig. 3 is a graph showing the results of an extrusion load test of an embodiment of the present invention. Figure 4 is a front elevational view of the PTP package of the present invention. Figure 5 is a right side view of the PTP package of the present invention. Figure 6 is a left side view of the PTP package of the present invention. Figure 7 is a plan view of the PTP package of the present invention. Figure 8 is a bottom plan view of the PTP package of the present invention. Figure 9 is a cross-sectional view of the PTP package A-A of Figure 1. Figure 10 (a) is a cross-sectional view of the PTP package B-B of Figure 1, and (b) is an enlarged view of (a). Fig. 11 is an explanatory view of a PTP package of a conventional example.

本實施形態係關於一種PTP包裝體之發明,其特徵在於:具備收納醫藥品製劑之袋部,袋部之頂面相對於蓋材傾斜。 The present invention relates to a PTP package according to the invention, characterized in that it comprises a bag portion for accommodating a pharmaceutical preparation, and a top surface of the bag portion is inclined with respect to the lid member.

如圖1所示,本實施形態之PTP包裝體1主要由收容醫藥品製劑2之PTP片材3、與貼合於PTP片材3之底面側的蓋材4構成。 As shown in FIG. 1, the PTP package 1 of the present embodiment is mainly composed of a PTP sheet 3 containing the pharmaceutical preparation 2 and a lid member 4 bonded to the bottom surface side of the PTP sheet 3.

再者,於圖1中觀察時,PTP包裝體1之長邊方向的近前側成為正面側。 In addition, when viewed in FIG. 1, the front side in the longitudinal direction of the PTP package 1 becomes the front side.

PTP包裝體1係將醫藥品製劑2自PTP片材3側向蓋材4側擠出而將其取出的包裝體。 The PTP package 1 is a package in which the pharmaceutical preparation 2 is extruded from the PTP sheet 3 side to the lid member 4 side and taken out.

再者,PTP包裝體1之形狀雖形成為略呈矩形,但並不限定於此,可根據醫藥品製劑2之形狀或數量等進行適當變更。 In addition, although the shape of the PTP package 1 is formed in a substantially rectangular shape, the shape is not limited thereto, and may be appropriately changed depending on the shape or the number of the pharmaceutical preparation 2 or the like.

醫藥品製劑2係由片劑或膠囊劑等固體製劑構成。 The pharmaceutical preparation 2 is composed of a solid preparation such as a tablet or a capsule.

尤其,適於本實施形態之醫藥品製劑2係如口腔內崩解製劑等之類的脆弱固體製劑,且亦可收容自PTP包裝體擠出醫藥品製劑時藉由擠出力而容易破損者。 In particular, the pharmaceutical preparation 2 of the present embodiment is a fragile solid preparation such as an orally disintegrating preparation, and may be contained in a PTP package, and may be easily broken by extrusion force when the pharmaceutical preparation is extruded.

又,收納於PTP包裝體1之被包裝物並不限定於醫藥品製劑2,可作各種變更。例如,亦可將固體食品、各種裝飾品、或如鈕扣、電池之各種生 活用品等作為被包裝物。 Moreover, the packaged article accommodated in the PTP package 1 is not limited to the pharmaceutical preparation 2, and various modifications are possible. For example, solid foods, various decorations, or various kinds of materials such as buttons and batteries can also be used. Live goods and the like as a packaged object.

如圖2所示,醫藥品製劑2以長條之方向相對於蓋材4為大致水平之方式收納於PTP片材3之後述袋部20內。 As shown in FIG. 2, the pharmaceutical preparation 2 is accommodated in the bag portion 20 which will be described later in the PTP sheet 3 so that the direction of the strip is substantially horizontal with respect to the lid member 4.

PTP片材3係成形為略呈矩形之透明或有色的樹脂或金屬片材,如圖1所示,主要由形成平面狀基板之片材基板部10、與向片材基板部10之表面側突出的複數個袋部20構成。 The PTP sheet 3 is formed into a substantially rectangular transparent or colored resin or metal sheet, and is mainly composed of a sheet substrate portion 10 on which a planar substrate is formed and a surface side of the sheet substrate portion 10 as shown in FIG. A plurality of protruding pockets 20 are formed.

片材基板部10之長邊方向的一端變得比另一端寬,形成有使用者於處理PTP包裝體1時握持之把手部11。再者,片材基板部10之形狀只要為可對使用者提供之形狀,並無特別限制,可進行變更。 One end of the sheet substrate portion 10 in the longitudinal direction is wider than the other end, and a handle portion 11 that is gripped by the user when the PTP package 1 is processed is formed. Further, the shape of the sheet substrate portion 10 is not particularly limited as long as it can be provided to the user, and can be changed.

PTP片材3之具體原料較理想為PVC(聚氯乙烯)、PP(聚丙烯)、PCTFE(聚氯三氟乙烯)、及鋁等。再者,並不限定於該等原料,亦可使用眾所周知之樹脂、金屬材料。 The specific raw material of the PTP sheet 3 is preferably PVC (polyvinyl chloride), PP (polypropylene), PCTFE (polychlorotrifluoroethylene), and aluminum. Further, it is not limited to these raw materials, and a well-known resin or metal material can also be used.

PTP片材3為了確保剛性,且保持良好之成形性,係將成形前之厚度設定為約150~300μm之範圍而成形。 In order to ensure rigidity and maintain good formability, the PTP sheet 3 is formed by setting the thickness before molding to a range of about 150 to 300 μm.

尤其,較理想為將成形前之厚度設定為約200~250μm之範圍而成形。 In particular, it is preferred to form the thickness before forming to a range of about 200 to 250 μm.

藉由以此方式,可使用原有機械容易地成形不會產生褶皺且外觀優異之片材。 By this means, it is possible to easily form a sheet which does not cause wrinkles and which is excellent in appearance, using the original machine.

再者,PTP片材3之厚度並不限定於約150~300μm,可適當變更。PTP片材3之厚度只要在運輸時等不會發生破損,且當PTP片材3之袋部20被向蓋材4側擠出時可產生變形的程度即可。 In addition, the thickness of the PTP sheet 3 is not limited to about 150 to 300 μm, and can be appropriately changed. The thickness of the PTP sheet 3 is not damaged as long as it is transported, and the degree of deformation may be generated when the pocket portion 20 of the PTP sheet 3 is extruded toward the lid member 4 side.

蓋材4係由成形為略呈矩形之鋁材料構成,且以密封袋部20之方式貼合於PTP片材3底面。 The cover member 4 is made of an aluminum material which is formed into a substantially rectangular shape, and is bonded to the bottom surface of the PTP sheet 3 so as to seal the bag portion 20.

若使用鋁作為蓋材4之原料,則由於PTP包裝體1之耐濕性、遮光性會獲得提升,故而較理想,但亦可不特別限定為鋁。例如,亦可使用玻璃紙、如聚醯胺樹脂之眾所周知的樹脂素材等作為蓋材4之原料。 When aluminum is used as the material of the lid member 4, the moisture resistance and the light-shielding property of the PTP package 1 are improved, which is preferable, but it is not particularly limited to aluminum. For example, a cellophane, a well-known resin material such as a polyamide resin, or the like can be used as a raw material of the lid member 4.

蓋材4為了確保剛性,且保持良好之密封性,係將密封前之厚度設定為約15~20μm之範圍而進行密封。尤其,較理想為將密封前之厚度設定為約17~20μm而進行密封。其原因在於:藉由以此方式,使氣密性高之容器變得再現性良好且易於穩定地生產。 In order to ensure rigidity and to maintain good sealing properties, the lid member 4 is sealed by setting the thickness before sealing to a range of about 15 to 20 μm. In particular, it is preferable to perform sealing by setting the thickness before sealing to about 17 to 20 μm. This is because, in this way, the container having high airtightness is made to have good reproducibility and is easy to produce stably.

再者,蓋材4之厚度並不限定於約15~20μm,可適當變更。蓋材4之厚度只要在運輸時等不會發生破損,且當自PTP包裝體1擠破蓋材4而擠出醫藥品製劑2時為容易擠破的程度即可。 Further, the thickness of the lid member 4 is not limited to about 15 to 20 μm, and can be appropriately changed. The thickness of the lid member 4 is not to be damaged when transported, and the like, and when the lid material 4 is squeezed from the PTP package 1 to extrude the pharmaceutical preparation 2, it is easy to be crushed.

如圖1所示,於PTP包裝體1設置有10個袋部20,具體而言,於PTP包裝體1之長邊方向隔著特定間隔設置有5個,並且5個袋部20沿著與PTP包裝體1之長邊方向垂直之方向設置成2行。 As shown in FIG. 1, the PTP package 1 is provided with ten pockets 20, specifically, five in the longitudinal direction of the PTP package 1 at a predetermined interval, and five pockets 20 are arranged along the same The direction in which the longitudinal direction of the PTP package 1 is perpendicular is set to two rows.

另,袋部之個數及配置當然不限定於此,可進行變更。又,所有的袋部20並不限定於相同形狀,亦可根據醫藥品製劑2之形狀,使袋部20之形狀各不相同。 Further, the number and arrangement of the bag portions are of course not limited thereto, and can be changed. Further, all of the bag portions 20 are not limited to the same shape, and the shape of the bag portion 20 may be different depending on the shape of the pharmaceutical preparation 2.

如圖2所示,袋部20之橫剖面略呈圓形,袋部20係由豎設於片材基板部10之表面上的側壁21、與設置於側壁21之上方端部的頂面22構成。 As shown in FIG. 2, the pocket portion 20 has a substantially circular cross section, and the pocket portion 20 is formed by a side wall 21 erected on the surface of the sheet substrate portion 10 and a top surface 22 provided at an upper end portion of the side wall 21. Composition.

再者,袋部20之橫剖面雖形成為略呈圓形,但並不限定於此,可根據醫藥品製劑2之形狀適當變更。 Further, although the cross section of the bag portion 20 is formed in a substantially circular shape, the present invention is not limited thereto, and may be appropriately changed depending on the shape of the pharmaceutical preparation 2.

側壁21相當於袋部20之側部,形成為以袋部20上下方向之中心軸23a為中心之大致圓錐狀且上端由斜面切斷的形狀,且自片材基板部10之表面延伸至上方。 The side wall 21 corresponds to the side portion of the pocket portion 20, and has a substantially conical shape centering on the central axis 23a of the pocket portion 20 in the vertical direction and a shape in which the upper end is cut by the inclined surface, and extends from the surface of the sheet substrate portion 10 to the upper side. .

又,側壁21整體,相對於垂直蓋材4之方向以特定角度向袋部20之內側,即袋部20之中心軸23a側傾斜。 Further, the entire side wall 21 is inclined toward the inner side of the pocket portion 20, that is, the side of the central axis 23a of the pocket portion 20 at a specific angle with respect to the direction of the vertical cover member 4.

此時,如圖2所示,於在PTP包裝體1之長邊方向觀察袋部20之剖面時,側壁21與蓋材4所形成之接地角度α係設定在30°≦α< 90°之範圍。 At this time, as shown in FIG. 2, when the cross section of the pocket portion 20 is observed in the longitudinal direction of the PTP package 1, the grounding angle α formed by the side wall 21 and the cover member 4 is set at 30 ° ≦ α < 90° range.

藉由以此方式將接地角度α設定為銳角,而於袋部20被向蓋材側擠出時,側壁21變得容易倒向內側,因此可使袋部20容易凹陷。 By setting the ground angle α to an acute angle in this manner, when the pocket portion 20 is extruded toward the lid member side, the side wall 21 is easily inverted to the inner side, so that the pocket portion 20 can be easily recessed.

尤其,較理想為將接地角度α之範圍設定為60°≦α<90°。 In particular, it is preferable to set the range of the ground angle α to 60° ≦ α < 90°.

藉由以此方式,可根據醫藥品製劑2之形狀適當調整袋部20之橫剖面積,從而可將大量之醫藥品製劑2收容於PTP包裝體1。 By this means, the cross-sectional area of the bag portion 20 can be appropriately adjusted according to the shape of the pharmaceutical preparation 2, and a large amount of the pharmaceutical preparation 2 can be accommodated in the PTP package 1.

例如,於將略呈橢圓形之醫藥品製劑2上下收納於長條之方向的情形時,藉由增大接地角度α,可將袋部20之橫剖面積調整為較小,因此,可於PTP包裝體1形成多個袋部20,從而可收容醫藥品製劑2。 For example, when the slightly elliptical pharmaceutical preparation 2 is vertically stored in the direction of the strip, the cross-sectional area of the pocket portion 20 can be adjusted to be small by increasing the ground angle α. The PTP package 1 forms a plurality of pockets 20 so that the pharmaceutical preparation 2 can be accommodated.

再者,本實施形態之接地角度α的範圍係設定為30°≦α<90°,但只要為可收納醫藥品製劑2之範圍內,亦可不被限定。例如,為了確保側壁21之剛性,亦可將接地角度α設定為90°。 Further, the range of the ground angle α in the present embodiment is set to 30° ≦ α < 90°, but it is not limited as long as it is within the range in which the pharmaceutical preparation 2 can be accommodated. For example, in order to secure the rigidity of the side wall 21, the ground angle α may be set to 90°.

如圖2所示,於側壁21形成有高度形成為最低之第1部分21a、與高度形成為最大高之第2部分21b,第1部分21a與第2部分21b隔著頂面22而相互位於直徑方向之相反側。 As shown in FIG. 2, the first portion 21a having the lowest height and the second portion 21b having the highest height are formed on the side wall 21, and the first portion 21a and the second portion 21b are located opposite each other across the top surface 22. The opposite side of the diameter direction.

於圖1中觀察時,第1部分21a於PTP包裝體1之長邊方向上係位於與把手部11相反側的部分,且於與PTP包裝體1之長邊方向正交之方向上係位於袋部20之大致中央的部分。 As seen in FIG. 1, the first portion 21a is located on the opposite side of the handle portion 11 in the longitudinal direction of the PTP package 1, and is located in a direction orthogonal to the longitudinal direction of the PTP package 1. A substantially central portion of the pocket portion 20.

於圖1中觀察時,第2部分21b於PTP包裝體1之長邊方向上係位於把手部11側的部分,且於與PTP包裝體1之長邊方向正交之方向上係位於袋部20之大致中央的部分。 As seen in FIG. 1, the second portion 21b is located on the side of the handle portion 11 in the longitudinal direction of the PTP package 1, and is located in the pocket portion in the direction orthogonal to the longitudinal direction of the PTP package 1. The roughly central part of 20.

側壁21之第1部分21a及第2部分21b配置成使頂面22之中心22a置於連結第1部分21a及頂面22相交之部分與第2部分21b及頂面22相交之部分的直線上。 The first portion 21a and the second portion 21b of the side wall 21 are disposed such that the center 22a of the top surface 22 is placed on a line connecting a portion where the first portion 21a and the top surface 22 intersect with the portion where the second portion 21b and the top surface 22 intersect. .

本實施形態之側壁21的整體相對於蓋材4以接地角度α向 袋部20之內側傾斜,但並不限定於此,可進行變更。 The entire side wall 21 of the present embodiment is oriented at a ground angle α with respect to the lid member 4. The inside of the bag portion 20 is inclined, but the present invention is not limited thereto and can be changed.

例如,亦可形成為側壁21中之第1部分21a及第2部分21b向袋部20之內側傾斜,其他部分延伸於垂直蓋材4之方向。又,亦可僅使側壁21中之第1部分21a向袋部20之內側傾斜。再者,接地角度α亦可於21a及21b側為不同之值。 For example, the first portion 21a and the second portion 21b of the side wall 21 may be formed to be inclined toward the inner side of the pocket portion 20, and the other portions may extend in the direction perpendicular to the vertical cover member 4. Further, only the first portion 21a of the side wall 21 may be inclined toward the inner side of the pocket portion 20. Further, the ground angle α may be a different value on the sides 21a and 21b.

於側壁21之下方端部與片材基板部10之表面抵接的角部24賦予有曲率半徑R。因此,確保角部24之剛性,將成形性保持為良好。 A corner portion 24 that abuts against the surface of the sheet substrate portion 10 at the lower end portion of the side wall 21 is given a radius of curvature R. Therefore, the rigidity of the corner portion 24 is ensured, and the formability is kept good.

再者,角部24之曲率半徑R可適當變更大小,又,亦可於角部24在全周中局部性地賦予有曲率半徑R。亦可未對角部24賦予曲率半徑R。 Further, the radius of curvature R of the corner portion 24 can be appropriately changed in size, and the radius of curvature R can be locally imparted to the corner portion 24 over the entire circumference. The corner radius 24 may not be given a radius of curvature R.

頂面22相當於袋部20之上部,係形成為大致圓形平板狀。 The top surface 22 corresponds to the upper portion of the pocket portion 20 and is formed in a substantially circular flat shape.

本實施形態之頂面22的形狀,雖根據醫藥品製劑2之形狀而形成為大致圓形,但並不限定於此,除大致圓形外亦可形成為大致橢圓形。 The shape of the top surface 22 of the present embodiment is formed into a substantially circular shape according to the shape of the pharmaceutical preparation 2, but the shape is not limited thereto, and may be substantially elliptical in addition to a substantially circular shape.

若頂面22之形狀為大致圓形或大致橢圓形,則成為使用者容易利用手指抵壓PTP包裝體1之頂面22的形狀。 When the shape of the top surface 22 is a substantially circular shape or a substantially elliptical shape, the shape of the top surface 22 of the PTP package 1 can be easily pressed by a user with a finger.

又,頂面22之形狀除此以外可適當變更為大致半橢圓形或多角形等。 Further, the shape of the top surface 22 can be appropriately changed to a substantially semi-elliptical shape, a polygonal shape, or the like.

頂面22只要形成為拇指容易抵壓之大小,則可無特別限定地進行變更。例如,可為直徑3.5cm以下,更佳為直徑2cm以下。若頂面22為大致圓形,可為直徑約0.1~3.5cm,更佳為直徑約0.1~2cm,更進一步較佳為約0.3~1.5cm。 The top surface 22 can be changed without particular limitation as long as it is formed so that the thumb is easily pressed. For example, it may be 3.5 cm or less in diameter, more preferably 2 cm or less in diameter. If the top surface 22 is substantially circular, it may have a diameter of about 0.1 to 3.5 cm, more preferably about 0.1 to 2 cm in diameter, still more preferably about 0.3 to 1.5 cm.

如圖1及圖2所示,頂面22於PTP包裝體1之長邊方向相對於蓋材4以特定角度向正面側傾斜。換言之,頂面22以使中心軸23a相對於蓋材4以特定角度向正面側傾斜而成的中心軸23b為中心,形成為大致圓形平板狀。 As shown in FIGS. 1 and 2, the top surface 22 is inclined toward the front side at a specific angle with respect to the lid member 4 in the longitudinal direction of the PTP package 1. In other words, the top surface 22 is formed in a substantially circular flat shape centering on the central axis 23b in which the central axis 23a is inclined toward the front side with respect to the lid member 4 at a specific angle.

於將頂面22與蓋材4所形成之傾斜角度設為θ時,換言之,於將中心軸23a與中心軸23b所形成之傾斜角度設為θ時,如圖2所 示,傾斜角度θ係設定在5°≦θ≦70°之範圍。 When the inclination angle formed by the top surface 22 and the lid member 4 is θ, in other words, when the inclination angle formed by the central axis 23a and the central axis 23b is θ, as shown in FIG. 2 It is shown that the inclination angle θ is set in the range of 5° ≦ θ ≦ 70°.

尤其,較理想為將傾斜角度θ之範圍設定為5°≦θ≦20°。 In particular, it is preferable to set the range of the inclination angle θ to 5° ≦ θ ≦ 20°.

藉由以5°為下限值設定本實施形態之傾斜角度θ,可實現自PTP包裝體1取出醫藥品製劑2時之擠壓性的提升。 By setting the inclination angle θ of the present embodiment at a lower limit of 5°, it is possible to improve the squeezing property when the pharmaceutical preparation 2 is taken out from the PTP package 1 .

又,藉由以20°為上限值設定傾斜角度θ,PTP包裝體1可成為使用者更加容易利用手指抵壓頂面22之形狀。 Further, by setting the inclination angle θ with the upper limit of 20°, the PTP package 1 can make the shape of the top surface 22 more easily pressed by the user with the finger.

進而較理想為,若將袋部之傾斜角度θ設定為5°≦θ≦15°,則成為可考慮製造成本進行製造之範圍。 Further, it is preferable that when the inclination angle θ of the bag portion is set to 5° ≦ θ ≦ 15°, the manufacturing range can be considered in consideration of the manufacturing cost.

進而較理想為,若將袋部之傾斜角度θ設定為10°≦θ≦15°,則可使袋部成為更進一步容易凹陷之形狀。 Further, preferably, when the inclination angle θ of the pocket portion is set to 10° ≦ θ ≦ 15°, the pocket portion can be further recessed.

再者,只要在可收納醫藥品製劑2之範圍內,且設定有使袋部容易凹陷之傾斜角度θ,則傾斜角度θ亦可不特別限定。 In addition, the inclination angle θ is not particularly limited as long as the inclination angle θ at which the bag portion is easily recessed is set within the range in which the pharmaceutical preparation 2 can be accommodated.

本實施形態之頂面22相對於蓋材4於長邊方向上以傾斜角度θ向與把手部11相反之側傾斜,但並不限定於此,亦可於長邊方向上向把手部11側、與長邊方向正交之方向之一側傾斜。 The top surface 22 of the present embodiment is inclined to the side opposite to the handle portion 11 at an inclination angle θ with respect to the lid member 4 in the longitudinal direction. However, the present invention is not limited thereto, and may be directed to the handle portion 11 side in the longitudinal direction. It is inclined to one side of the direction orthogonal to the longitudinal direction.

又,本實施形態之頂面22的整體雖相對於蓋材4傾斜,但並不限定於此,亦可使頂面22局部性地相對於蓋材4傾斜。亦即,可僅使頂面22之上表面側相對於蓋材4傾斜,或者亦可使頂面22具備相對於蓋材4傾斜之傾斜部。 Further, although the entire top surface 22 of the present embodiment is inclined with respect to the lid member 4, the present invention is not limited thereto, and the top surface 22 may be partially inclined with respect to the lid member 4. That is, only the upper surface side of the top surface 22 may be inclined with respect to the lid member 4, or the top surface 22 may be provided with an inclined portion inclined with respect to the lid member 4.

並且,本實施形態之頂面22雖相對於蓋材4傾斜,但並不限定於此,亦可相對於平面狀之片材基板部10傾斜,又,亦可相對於由側壁21之蓋材4側之端部形成之平面傾斜。 Further, although the top surface 22 of the present embodiment is inclined with respect to the lid member 4, the present invention is not limited thereto, and may be inclined with respect to the planar sheet substrate portion 10, or may be opposed to the lid member of the side wall 21. The plane formed by the ends of the 4 sides is inclined.

頂面22與側壁21抵接之角部25係形成為略呈圓周狀,且遍及全周賦予有曲率半徑R。因此,確保角部25之剛性並將成形性保持為良好。又,由於對角部25賦予有曲率半徑R,故而於使用者將手指抵壓在 袋部20之頂面22時,手指並無不適感。 The corner portion 25 where the top surface 22 abuts against the side wall 21 is formed in a substantially circumferential shape, and is provided with a radius of curvature R throughout the entire circumference. Therefore, the rigidity of the corner portion 25 is ensured and the formability is kept good. Moreover, since the diagonal portion 25 is given the radius of curvature R, the user presses the finger against it. When the top surface 22 of the bag portion 20 is used, the finger has no discomfort.

再者,角部25之曲率半徑R可適當變更大小,又,亦可於角部25在全周中局部性地賦予有曲率半徑R。亦可未對角部25賦予曲率半徑R。 Further, the radius of curvature R of the corner portion 25 can be appropriately changed in size, and the radius of curvature R can be locally imparted to the corner portion 25 over the entire circumference. The corner radius 25 may not be given a radius of curvature R.

本實施形態之頂面22雖形成為大致平板狀,但作為其他實施形態,亦可於頂面22之表面上另外賦予凹凸。藉由如此般於頂面22之表面上賦予凹凸,於使用者利用手指擠出頂面22時,頂面22之凹凸會止滑。因此,變得容易利用手指擠出頂面22。 Although the top surface 22 of this embodiment is formed in a substantially flat shape, as another embodiment, unevenness may be additionally provided on the surface of the top surface 22. By providing the unevenness on the surface of the top surface 22 as described above, when the user extrudes the top surface 22 with a finger, the unevenness of the top surface 22 is prevented from slipping. Therefore, it becomes easy to extrude the top surface 22 with a finger.

又,藉由對頂面22賦予凹凸,頂面22之柔軟性會獲得提升。 Further, by imparting irregularities to the top surface 22, the flexibility of the top surface 22 is improved.

作為對頂面22賦予之凹凸形狀,例如可採用指紋形狀、點形狀、星形狀等。 As the uneven shape given to the top surface 22, for example, a fingerprint shape, a dot shape, a star shape, or the like can be employed.

尤其藉由在頂面22之表面上的大致中央處賦予指紋形狀,可容易利用手指擠出頂面22,且可確保頂面22之剛性,進而使用者可容易自PTP包裝體1確認頂面22之位置。作為具體之指紋形狀,可例舉凹凸呈放射狀(同心圓狀)延伸之形狀。 In particular, by imparting a fingerprint shape at substantially the center of the surface of the top surface 22, the top surface 22 can be easily extruded by fingers, and the rigidity of the top surface 22 can be ensured, so that the user can easily confirm the top surface from the PTP package 1. 22 location. The specific fingerprint shape may be a shape in which the irregularities are radially (concentrically) extended.

<實施例> <Example>

以下,對本發明之實施例詳細地進行說明。再者,本發明並不限定於本實施例。 Hereinafter, embodiments of the invention will be described in detail. Furthermore, the present invention is not limited to the embodiment.

PTP包裝體1之本實施例的構成如下。 The configuration of this embodiment of the PTP package 1 is as follows.

醫藥品製劑2:Gaster(註冊商標)D錠20mg(安斯泰來製藥股份有限公司製造) Pharmaceutical preparation 2: Gaster (registered trademark) D ingot 20 mg (manufactured by Astellas Pharmaceutical Co., Ltd.)

PTP片材3:PVC 200μm(VSS-F110,住友Bakelite股份有限公司製造) PTP sheet 3: PVC 200 μm (VSS-F110, manufactured by Sumitomo Bakelite Co., Ltd.)

蓋材4:鋁17μm(純,住輕鋁箔股份有限公司製造) Cover material 4: Aluminum 17μm (pure, manufactured by Light Aluminum Foil Co., Ltd.)

PTP包裝體1係藉由以下方式製造:使用泡殼包裝機(FBP-600UC,CKD股份有限公司製造)自PVC 200μm成形PTP片材3之後, 將醫藥品製劑2收容於PTP片材3,並於PTP片材3之背面密封由鋁17μm構成之蓋材4。 The PTP package 1 was manufactured by using a blister packaging machine (FBP-600UC, manufactured by CKD Co., Ltd.) to form the PTP sheet 3 from PVC 200 μm. The pharmaceutical preparation 2 was placed in the PTP sheet 3, and the lid member 4 made of aluminum 17 μm was sealed on the back surface of the PTP sheet 3.

將泡殼包裝機之成形條件示於下述表1。 The molding conditions of the blister packaging machine are shown in Table 1 below.

當成形PTP片材3之袋部20時,藉由變更泡殼包裝機之成形模塞的形狀,而以袋部20之傾斜角度θ成為5°、10°、及15°之方式成形,並分別設為PTP包裝體1之實施例1、實施例2、及實施例3。 When the bag portion 20 of the PTP sheet 3 is formed, the shape of the forming plug of the blister packaging machine is changed, and the inclination angle θ of the bag portion 20 is formed to be 5°, 10°, and 15°, and The first embodiment, the second embodiment, and the third embodiment of the PTP package 1 are respectively provided.

其次,使用袋部20之傾斜角度θ不同之實施例1、實施例2、實施例3的PTP包裝體1,測定將袋部20向蓋材4側擠出時之荷重。 Next, using the PTP package 1 of Example 1, Example 2, and Example 3 in which the inclination angle θ of the bag portion 20 is different, the load when the bag portion 20 is extruded toward the lid member 4 side is measured.

再者,作為對照組,根據表1之條件,準備袋部20之傾斜角度θ為0°之PTP包裝體。 Further, as a control group, a PTP package in which the inclination angle θ of the bag portion 20 was 0° was prepared according to the conditions of Table 1.

試驗方法如下。 The test method is as follows.

使用萬能試驗機(AGS-J,島津製作所股份有限公司製造)對各PTP包裝體1之頂面22施加朝向蓋材4側於鉛垂方向擠出之荷重。測定醫藥品製劑2自各PTP包裝體1被擠出使蓋材4破裂為止之擠出荷重。 The top surface 22 of each PTP package 1 was subjected to a load which was extruded in the vertical direction toward the lid member 4 side by using a universal testing machine (AGS-J, manufactured by Shimadzu Corporation). The extrusion load of the pharmaceutical preparation 2 from the extrusion of each PTP package 1 to break the lid member 4 was measured.

將擠出速度設定為15mm/分鐘,並使用直徑7.93mm之擠出棒(SUS:Steel Use Stainless製)。對各PTP包裝體1實施3次試驗。 The extrusion speed was set to 15 mm/min, and an extruded rod (SUS: Steel Use Stainless) having a diameter of 7.93 mm was used. Three tests were performed on each PTP package 1.

將擠出荷重試驗之結果示於圖3及下述表2。 The results of the extrusion load test are shown in Fig. 3 and Table 2 below.

於圖3中,擠出荷重(Force)之小波峰係表示PTP包裝體1之頂面22向蓋材4側凹陷時的荷重,擠出荷重之大波峰則表示醫藥品製劑2自袋部20被擠出使蓋材4破裂時的荷重。 In FIG. 3, the small peak of the extrusion load (Force) indicates the load when the top surface 22 of the PTP package 1 is recessed toward the cover member 4 side, and the large peak of the extrusion load indicates the pharmaceutical preparation 2 from the bag portion 20. The load when the cover material 4 is broken is extruded.

若嘗試評價頂面22向蓋材4側凹陷時之平均荷重,則可確認對照組之擠出荷重較大,而實施例1之擠出荷重較小。 When an attempt was made to evaluate the average load when the top surface 22 was recessed toward the lid member 4 side, it was confirmed that the extrusion load of the control group was large, and the extrusion load of Example 1 was small.

亦即,可確認隨著袋部20之傾斜角度θ變大,可發揮袋部20之頂面22變得容易向蓋材4側凹陷之效果。 In other words, it can be confirmed that as the inclination angle θ of the bag portion 20 becomes larger, the top surface 22 of the bag portion 20 can be easily recessed toward the lid member 4 side.

再者,如圖3所示,表2中之”-”所示之意為,實施例2、實施例3未確認到頂面22凹陷時之荷重的波峰。 Further, as shown in Fig. 3, the "-" in Table 2 means that the peaks of the load when the top surface 22 is recessed are not confirmed in the embodiment 2 and the third embodiment.

其次,若嘗試評價蓋材4破裂時之平均荷重,則可確認對照組成為最大之擠出荷重,且依實施例1、實施例2、實施例3之順序擠出荷重變小。 Next, when an attempt was made to evaluate the average load when the cover material 4 was broken, it was confirmed that the control group became the maximum extrusion load, and the extrusion load was small in the order of Example 1, Example 2, and Example 3.

亦即,可確認隨著袋部20之傾斜角度θ依序變大為5°、10°、15°,可發揮變得容易自袋部20擠出醫藥品製劑2之效果。 In other words, it is confirmed that the inclination angle θ of the bag portion 20 is increased to 5°, 10°, and 15° in order, and the effect of easily extruding the pharmaceutical preparation 2 from the bag portion 20 can be exhibited.

於上述實施形態,主要對本發明之PTP包裝體進行了說明。 In the above embodiment, the PTP package of the present invention has been mainly described.

但是,上述實施形態只不過為用以使本發明容易理解之一例示,並非限定本發明者。當然,本發明在不脫離其主旨之情況下,可進行變更、改良,並且當然本發明包含其對等物。 However, the above embodiments are merely illustrative of the present invention and are not intended to limit the invention. It is a matter of course that the invention may be modified or modified without departing from the spirit and scope of the invention.

2‧‧‧醫藥品製劑 2‧‧‧Pharmaceutical preparations

4‧‧‧蓋材 4‧‧‧Cleaning

10‧‧‧片材基板部 10‧‧‧Sheet substrate unit

20‧‧‧袋部 20‧‧‧ bag department

21‧‧‧側壁 21‧‧‧ side wall

21a‧‧‧第1部分 21a‧‧‧Part 1

21b‧‧‧第2部分 21b‧‧‧Part 2

22‧‧‧頂面 22‧‧‧ top surface

22a‧‧‧中心 22a‧‧ Center

23a、23b‧‧‧中心軸 23a, 23b‧‧‧ central axis

24、25‧‧‧角部 24, 25‧‧‧ corner

α‧‧‧接地角度 Α‧‧‧ grounding angle

θ‧‧‧傾斜角度 Θ‧‧‧ tilt angle

Claims (10)

一種PTP包裝體,具備:PTP(Press Through Package)片材:其具有向片材表面側突出之凸狀袋部,可將被包裝物收容於該袋部,與蓋材:其以密封該袋部之方式貼合於該PTP片材背面;該袋部係由豎設於該片材表面側之側壁、與形成於該側壁之該蓋材相反側之端部的頂面構成,該頂面相對於該蓋材中之由該側壁包圍的部分傾斜。 A PTP package comprising: a PTP (Press Through Package) sheet having a convex pocket portion protruding toward a surface side of the sheet, the packaged article being accommodated in the pocket portion, and a cover material: the bag is sealed a portion attached to the back surface of the PTP sheet; the bag portion is formed by a side wall erected on a side surface of the surface of the sheet and a top surface formed on an opposite end side of the cover material of the side wall, the top surface phase The portion of the cover material that is surrounded by the side wall is inclined. 如申請專利範圍第1項之PTP包裝體,其中,該側壁以位於該袋部內側之方式相對於該蓋材中之由該側壁包圍的部分傾斜。 A PTP package according to claim 1, wherein the side wall is inclined with respect to a portion of the cover member surrounded by the side wall in a manner of being inside the bag portion. 如申請專利範圍第1或2項之PTP包裝體,其中,該側壁具備該側壁中之形成為最低的第1部分、與相對於該第1部分隔著該頂面而位於相反側且形成為高於該第1部分的第2部分。 The PTP package according to claim 1 or 2, wherein the side wall has a first portion which is formed to be the lowest in the side wall, and is located on the opposite side of the first surface with respect to the first portion, and is formed as Higher than the second part of the first part. 如申請專利範圍第3項之PTP包裝體,其中,該側壁中之該第2部分係形成為最高。 The PTP package of claim 3, wherein the second portion of the sidewall is formed to be the highest. 如申請專利範圍第1或2項之PTP包裝體,其中,該頂面係由大致平板狀構成。 The PTP package according to claim 1 or 2, wherein the top surface is formed in a substantially flat shape. 如申請專利範圍第1或2項之PTP包裝體,其中,該頂面係由選自包含大致圓形、大致橢圓形及大致多角形之群中的任一種形狀構成。 The PTP package according to claim 1 or 2, wherein the top surface is formed of any one selected from the group consisting of a substantially circular shape, a substantially elliptical shape, and a substantially polygonal shape. 如申請專利範圍第1或2項之PTP包裝體,其中,該被包裝物為醫藥品製劑。 The PTP package according to claim 1 or 2, wherein the packaged product is a pharmaceutical preparation. 如申請專利範圍第1或2項之PTP包裝體,其中,該頂面與該蓋材中之由該側壁包圍之部分所形成的角度θ為5°≦θ≦70°。 The PTP package according to claim 1 or 2, wherein an angle θ formed by the top surface and a portion of the lid member surrounded by the side wall is 5° ≦ θ ≦ 70°. 如申請專利範圍第8項之PTP包裝體,其中,該θ為5°≦θ≦20°。 A PTP package according to claim 8 wherein the θ is 5° ≦ θ ≦ 20°. 如申請專利範圍第8項之PTP包裝體,其中,該θ為10°≦θ≦15°。 A PTP package according to claim 8 wherein the θ is 10° ≦ θ ≦ 15°.
TW102136432A 2012-10-10 2013-10-09 Ptp package TW201414468A (en)

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