TW201328668A - Arterial hardening inspection method and apparatus thereof - Google Patents

Abstract

An arterial hardening inspection method is disclosed. The method comprises a preparation step, a first measurement step, a pressing step, a second measurement step, a processing step and a display step. Further, an arterial hardening inspection apparatus is disclosed. The apparatus comprises a pressing module, a measurement module and a control module. The pressing module has a elastic member mounted on a base. The elastic member has a pressing end that is capable of moving back and forth in a linear manner. The measurement module has a sensor with a sensing end. The control module has a data processing unit and an interface. The data processing unit electrically connects to the interface, the elastic member and the sensor.

Description

Arterial wall hardness detecting method and device thereof

The invention relates to a method for detecting the hardness of an arterial wall, in particular to a method for detecting the hardness of an arterial wall by evaluating the degree of arteriosclerosis by the difference of the amplitude of the vibration after compression of the soft tissue of the blood vessel wall.

According to medical literature, Arterial Hardening is closely related to many diseases, such as: Cerebral Vessel Disease, Cardiac Disease, Diabetes Mellitus, Hypertension ( Hypertension) and a considerable proportion of kidney diseases (Renal Disease).

Among them, the degree of arterial wall sclerosis can be used as atherosclerosis of the cardiovascular system, Ventricular Hypertrophy, Congestive Heart Failure, Coronary Arterial Disease, and heart rate irregularity ( Arrhythmia), the main predictor of lesions such as Valvular Disease. In view of this, how to estimate the degree of arterial wall sclerosis and exert the effect of "early diagnosis and early treatment" to reduce the incidence of the above diseases (Morbidity) and mortality (Mortality) will be the key to national health.

There are many techniques for estimating the degree of hardening of the arterial wall, such as the Pulse Transit Time analysis technique, which utilizes the coefficient of elasticity (E) and pulse wave velocity (Pulse Wave Velocity, PWV) of the vessel wall. ), the relationship between the size of the vessel diameter (r), the thickness of the vessel wall (h), and the blood density (ρ), E = (PWV ² × 2rρ) / h, to indirectly estimate the degree of arterial wall wall hardening. However, by measuring by this technique, in addition to the pulse wave that can be transmitted to the blood vessel in advance, since the blood vessel density of the pulse wave transmission path is not completely the same, the pulse wave transit time cannot properly represent the arterial wall. The degree of hardening.

In addition, Ultrasound Echo Tracking is used to estimate the degree of arterial wall sclerosis. For example, the Republic of China Announcement No. I227665, "Method for detecting non-invasive vascular mechanical viscoelastic properties", discloses a case. Knowing the arterial wall hardness test method, using the ultrasonic image scanning device to synchronize the blood pressure and blood vessel diameter experimental measurement system, and obtaining the blood vessel diameter and blood pressure data of several heartbeat cycles by image processing technology, thereby establishing blood pressure and blood vessel tube The dynamic characteristics of the diameter and the wall tissue strain, for example, the stress-strain relationship curve of the vessel diameter or Intima-Media Thickness (IMT), the dynamic Young's modulus and the viscoelastic energy loss rate (Energy) Dissipation Ratio (EDR), etc., as the basis for estimating the degree of hardening of the arterial wall.

Among them, the accuracy of the ultrasonic image depends on whether the resolution of the image is high enough. However, the ultrasonic image scanning device that can capture high-resolution images is expensive, and the operation process is complicated. The need for well-trained professionals to operate, the detection time is also very lengthy, and there is still room for improvement in clinical application. In addition, the dynamic Young's coefficient is calculated only by the stress-strain relationship curve. Obviously, the blood vessel is regarded as a single elastic material to calculate the elastic force, completely ignoring the influence of blood and blood vessel wall quality in the blood vessel, and therefore cannot be correct. It reflects the mechanical properties and degree of hardening of the blood vessel itself.

For the above reasons, it is indeed necessary to further improve the above-described conventional arterial wall hardness testing method.

The object of the present invention is to improve the above-mentioned shortcomings to provide a method for detecting the hardness of an arterial wall, which only needs to measure the vibration amplitude after compression of the soft tissue of the blood vessel wall, and evaluate the degree of arteriosclerosis by the difference of the vibration amplitude to reduce the device. Cost.

The second object of the present invention is to provide a method for detecting the hardness of an arterial wall, which can automatically measure the amplitude of vibration after compression of the soft tissue of the blood vessel wall, and evaluate the degree of arteriosclerosis by the difference in vibration amplitude to simplify the operation process.

Another object of the present invention is to provide an arterial wall hardness detecting device, which only needs to measure the vibration amplitude after the soft tissue of the blood vessel wall is pressed, and evaluate the degree of arterial atherosclerosis by the difference of the vibration amplitude to reduce the equipment cost.

In order to achieve the foregoing object, the technical content of the present invention includes:

The method for testing the hardness of an arterial wall includes: a preparation step of a part of the human body to be tested by a measuring module; and a first measuring step for measuring the part to be tested by the measuring module a vibration amount, and outputting a vibration sensing signal to a control module. After the control module obtains a reference amplitude difference according to the amplitude of the vibration sensing signal, the control module outputs a first pressure signal; The pressing step is to drive the pressure applying module by the starting pressure signal, so that the pressure applying module applies pressure to a pressing part of the human body, and after a pressing time, the control module outputs a stop application. Pressing the pressure signal to the pressure applying module, so that the pressure applying module stops applying pressure to the pressing portion; and a second measuring step, the vibration sensing signal of the measuring module is input by the control module, and After outputting the stop pressure signal, obtaining a first amplitude difference and a second amplitude difference according to the amplitude of the vibration sensing signal; and a calculating step, respectively, calculating, by the control module, the first amplitude difference And the second amplitude difference and the reference amplitude Ratio value, generating a first hardness value and a second index hardness index value; and a display step of displaying the first hardness index-based value and the second hardness index value by the control module.

The method for detecting the hardness of an arterial wall of the present invention, wherein the control module calculates the first hardness index value as follows:

Wherein R1 is the first hardness index value, A1 is the first amplitude difference value, and A0 is the reference amplitude difference value.

The method for detecting the hardness of an arterial wall of the present invention, wherein the control module calculates the second hardness index value as follows:

Wherein R2 is the second hardness index value, A2 is the second amplitude difference value, and A0 is the reference amplitude difference value.

The method for detecting an arterial wall hardness of the present invention, wherein the pressing time ranges from 0.5 to 3 seconds.

The method for detecting the hardness of an arterial wall of the present invention, wherein the part to be tested is a soft tissue appearance of a blood vessel of a human body.

The method for detecting the hardness of an arterial wall of the present invention, wherein the pressing portion is a soft tissue appearance adjacent to the portion to be tested.

The method for detecting the hardness of the arterial wall of the present invention, wherein the pressure applying module is pressed against the pressing portion by a telescopic member, and the measuring module obtains the reference amplitude difference by a sensing component, the control module has a data processing unit and an interface unit, the data processing unit is electrically connected to the telescopic member, the sensing member and the interface unit, and outputs the first hardness index value and the second hardness index value to the interface unit.

An arterial tube wall hardness detecting device comprises: a pressure applying module, which is disposed on a body by a telescopic member, the telescopic member has a linearly reciprocating pressing end; and a measuring module is provided with a sensing The sensing unit has a sensing end; and a control module is provided with a data processing unit and an interface unit. The data processing unit is electrically connected to the interface unit, the telescopic member and the sensing member.

The arterial tube wall hardness detecting device of the present invention, wherein the body is provided with a base, a vertical positioning member and a horizontal positioning member, the vertical positioning member is detachably coupled to the base, and the horizontal positioning member is translatably coupled The vertical positioning member is fixed to the telescopic member.

The arterial tube wall hardness detecting device of the present invention, wherein the measuring module is further provided with a coupling member, one end of the coupling member is provided with a horizontal adjusting hole and the body is combined, and the other end of the coupling member and the sensing member are One of the vertical adjustment holes is combined.

The above and other objects, features and advantages of the present invention will become more <RTIgt;

Referring to FIG. 1 , it is a system diagram of a preferred embodiment of the arterial wall hardness testing method of the present invention, wherein an arterial wall hardness detecting device is used to perform the arterial wall hardness testing method, the arterial tube The wall hardness detecting device comprises a pressure applying module 1, a measuring module 2 and a control module 3, wherein the pressing module 1 is used for pressing the soft tissue surface of the human body (ie, a pressing portion), the amount The measuring module 2 is configured to measure a physical characteristic of a part to be tested in the vicinity of the pressing portion (for example, a vibration amount before and after the pressing), and the control module 3 is electrically connected to the pressing module 1 and the measuring The module 2 is configured to control the pressure module 1 to be actuated, and the vibration change amount of the pressure portion is obtained by the measurement module 2 as a basis for estimating the degree of hardening of the blood vessel wall.

The pressing module 1 is provided with a telescopic member 11 which is made of a retractable electromagnet element (Solenoid), for example, a circular push-pull electromagnet (SH1679), and the telescopic member 11 is disposed on a body 12, the position of the telescopic member 11 can be fixed, and the telescopic member 11 has a pressing end 111. The pressing end 111 can linearly reciprocate and reciprocate toward the surface of the human body having a soft tissue of a blood vessel, for example: reciprocating The lifting movement is 0.2 to 2 cm (cm), etc., but not limited thereto, so as to apply pressure to the soft tissue of the human body for a predetermined period of time, for example, pressing soft tissue such as skin outside the arm artery. The body 12 is formed into any configuration in which the telescopic member 11 can be disposed, as exemplified below, but not limited thereto.

For example, as shown in FIG. 1 , the body 12 includes a base 121 , a vertical positioning member 122 , and a horizontal positioning member 123 . The vertical positioning member 122 is coupled to the base 121 for lifting and lowering, for example, locking. The horizontal positioning member 123 is rotatably coupled to the vertical positioning member 122, for example, a long slot or the like of the vertical positioning member 122, and the horizontal positioning member 123 is fixed to the vertical positioning member 122. The telescopic member 11 is fixedly coupled, so that the pressing end 111 of the telescopic member 11 can be moved up and down. The spatial position of the telescopic member 11 can be adjusted by the vertical positioning member 122 and the horizontal positioning member 123.

The measuring module 2 is provided with a sensing component 21, and the sensing component 21 is made of a vibration sensing component capable of converting the vibration amount of the object into an electrical signal, for example, a load component (Miniature S Beam Load Cell, Model) The sensing member 21 has a sensing end 211 for measuring the vibration amount of the soft tissue of the human body (for example, the skin outside the arm artery), and generating a vibration sensing signal, and the sensing member 21 and the The pressure-receiving module 1 can be combined or phase-separated, and the sensing member 21 is preferably adjustably coupled to the body 12 of the pressure-applying module 1, for example, by means of locking, snapping or bonding. The position of the sensing member 21 can be adjusted relative to the pressing module 1 , wherein when the sensing member 21 is coupled to the pressing module 1 , the sensing end 211 of the sensing member 21 is located The range of movement of the pressing end 111 of the telescopic member 11 (as shown in Figs. 4 and 6). In this embodiment, the measuring module 2 is further provided with a coupling member 22, and the coupling member 22 is locked and coupled with the sensing member 21 and the body 12 of the pressing module 1. A horizontal adjustment hole 221 (for example, a long slot) is combined with the body 12 (for example, a locking joint or the like) for adjusting the horizontal position of the sensing member 21, and the other end of the coupling member 22 and the feeling One of the vertical adjustment holes 212 (for example, a long slot) of the measuring member 21 is combined (for example, a locking joint or the like) for adjusting the vertical position of the sensing member 21.

The control module 3 is provided with a data processing unit 31 and an interface unit 32. The data processing unit 31 is composed of a device having data processing and storage functions, such as a microprocessor (Micro-Processor) and a digital information processor ( The data processing unit 31 is electrically connected to the telescopic member 11 of the pressing module 1 and the sensing member 21 of the measuring module 2 for sending a control signal (for example, a pulse signal) control. The telescopic member 11 is telescopically actuated and receives the vibration sensing signal of the sensing component 21, and the data processing unit 31 can store and execute a processing program to perform a numerical operation on the signal change of the sensing component 21 to generate a detection. result. The interface unit 32 is preferably formed by a touch screen. The interface unit 32 is electrically connected to the data processing unit 31 for displaying the detection result or for an operator to input data to the data processing unit 31. The control module 3 can also be provided with a signal processing unit 33. The signal processing unit 33 is electrically connected to the data processing unit 31 and the sensing component 21, and the vibration sensing signal of the sensing component 21 can be filtered by the signal. After the signal is amplified and the signal is converted, it is output to the data processing unit 31.

Referring to FIG. 3, it is a flow chart of a preferred embodiment of the arterial wall hardness testing method of the present invention, which comprises a preparation step S1, a first measurement step S2, a pressure application step S3, and a first The second measurement step S4, a calculation step S5 and a display step S6. Please refer to Figure 1 together, where:

The preparation step S1 is performed by the measurement module 2 against a part B to be tested of the human body, wherein the part B to be tested is a soft tissue appearance of the blood vessel of the human body. In this embodiment, the site B to be tested is taken as an embodiment of the skin of the human arm artery (as shown in FIG. 4). In detail, first, a test subject B is placed under the measurement module 2 (as shown in the figure), and then by an operator (for example, a medical staff or a testee) The position of the measuring module 2 is adjusted to make the sensing member 21 of the measuring module 2 interfere with the portion B to be tested. The sensing end 211 of the sensing member 21 is preferably slightly trapped in the portion The portion B to be tested allows the sensing member 21 to accurately measure the amplitude of the pulse vibration of the arterial blood vessel in the portion B to be tested (hereinafter referred to as the amount of vibration).

The first measuring step S2 is to measure the vibration amount of the portion B to be tested by the measuring module 2, and output a vibration sensing signal to the control module 3, and the control module 3 is to be based on the vibration. After the amplitude of the sensing signal obtains a reference amplitude difference A0, the control module 3 outputs an initial pressure signal. In detail, since the arterial blood vessel in the portion B to be tested generates periodic vibration, the sensing member 21 of the measuring module 2 can convert the vibration amount of the portion B to be tested into a vibration intensity of different strengths. The test signal, for example, different voltage values, etc., therefore, the control module 3 can record the amplitude of the artery vibration before the test is untested by the sampled value of the vibration sensing signal (Sampled Values), and store the artery The difference between the peak and the trough of the vibration amplitude is taken as the reference amplitude difference A0 (as shown in FIG. 5) to calculate the degree of arteriosclerosis, and then the control module 3 generates an initial pressure signal, for example: pulse The high level of the wave width modulation (PWM) signal is used to control the pressure module 1 to operate.

The pressing step S3 is to drive the pressing module 1 by the starting pressure signal, so that the pressing module 1 applies pressure to a pressing portion P of the human body, and after a pressing time T, the control is performed. The module 3 outputs a stop pressure signal to the pressure applying module 1 so that the pressure applying module 1 stops applying pressure to the pressing portion P, wherein the pressing portion P can be adjacent to the portion B to be tested. Soft tissue appearance. In detail, after the pressure applying module 1 receives the start pressure signal, the expansion member 11 is extended, and the pressing portion P is pressed by the pressing end 111, for example, adjacent to the portion B to be tested. The skin portion (as shown in Fig. 6), after the pressing time T (as shown in Fig. 5), for example, in the range of 0.5 to 3 seconds (Second), the control module 3 generates the stop pressure signal For example, the low level of the pulse width modulation (PWM) signal shortens the expansion member 11 and stops applying pressure to the pressing portion P (as shown in FIG. 4) to know The amount of vibration of the blood vessel in the pressure-applying portion P after a sudden change in state is used as a basis for calculating the degree of hardening of the blood vessel.

More specifically, when the blood vessel is subjected to an abnormal state such as compression or obstruction, the fluid resistance in the blood vessel increases, and in order to maintain a certain degree of blood flow, the human body adjusts the vibration amount of the pulse by itself, and when the blood vessel excludes the abnormal state, Adjusting the amount of vibration of the pulse again, wherein, when the blood vessel suddenly changes state, for example, from compression to non-compression, if the blood vessel (for example, the arterial blood vessel in the site B to be tested) is hardened, the blood vessel will be There is a large amount of instantaneous vibration; on the other hand, if the degree of hardening of the blood vessel is lower, the instantaneous vibration amount of the blood vessel is small. Therefore, the degree of vibration of the blood vessel can be accurately evaluated by using the magnitude of the instantaneous vibration of the blood vessel when the state changes.

In the second measuring step S4, the vibration sensing signal of the measuring module 2 is input by the control module 3, and after the stop pressure signal is output, the amplitude of the vibration sensing signal is obtained according to the amplitude of the vibration sensing signal. An amplitude difference A1 and a second amplitude difference A2. In detail, since the amount of vibration of the blood vessel in the pressing portion P after a sudden change of state can be used as a basis for calculating the degree of hardening of the blood vessel, and since the pressing portion P is adjacent to the portion B to be tested, The intensity of the vibration sensing signal measured by the measuring module 2 at the portion B to be tested (for example, a voltage value) changes, and the vibration amount of the blood vessel in the pressing portion P can be recorded, and the blood vessel is suddenly relaxed. The peak value and the valley difference of the amplitude can be used as a basis for calculating the degree of hardening of the blood vessel. Therefore, two amplitude difference values which are successively generated can be selected as the first amplitude difference value A1 and the second amplitude difference value A2 (eg, 5th) As shown in the figure, it is preferred to select the first and second amplitude differences after the blood vessel suddenly relaxes.

In the calculating step S5, the control module 3 calculates a ratio of the first amplitude difference and the second amplitude difference to the reference amplitude difference, respectively, to generate a first hardness index value and a second hardness index. value. In detail, since the reference amplitude difference represents a reference value before the blood vessel is not subjected to the hardness test, and the first amplitude difference value and the second amplitude difference value represent changes in the blood vessel after the hardness test, the control may be performed by the control. The data processing unit 31 of the module 3 respectively calculates a ratio of the first amplitude difference value and the second amplitude difference value to the reference amplitude difference value, and generates the first hardness index value and the second hardness index value, as follows (1) and (2):

Wherein R1 is the first hardness index value, R2 is the second hardness index value, A0 is the reference amplitude difference value, A1 is the first amplitude difference value, and A2 is the second amplitude difference value.

Table 1 Comparison of blood vessel hardness index of the subject

As can be seen from the above list 1, the vascular hardness index value of the smoking group (11 subjects with smoking), whether the mean or standard deviation is higher than the control group (21 non-smoking subjects) The blood vessel hardness index value indicates that the blood pressure of the subject having smoking is high, and the result is similar to the result of the related literature. Therefore, the first hardness index value and the second hardness index value can be used as evaluations. The reference value of the blood vessel hardness in the site B to be tested. In addition, the control module 3 can compare the first hardness index value and the second hardness index value with a plurality of threshold values (Threshold Values), and can be divided into several indicator categories, for example, high risk and low risk persons. Or normal indicator categories.

In the displaying step S6, the first hardness index value and the second hardness index value are displayed by the control module 3. In detail, the first hardness index value and the second hardness index value generated by the data processing unit 31 of the control module 3 can be output to the interface unit 32 of the control module 3 for the operator and the subject to be A reference for assessing the degree of vascular sclerosis.

The main technical feature of the method for detecting the hardness of the arterial wall of the present invention is that the measurement module 2 only needs to be in contact with the part B to be tested of the human body, and the control module 3 controls the The pressure applying module 1 and the measuring module 2 automatically obtain the reference amplitude difference A0 of the portion B to be tested, temporarily press the pressing portion P, obtain the first amplitude difference A1 and the second amplitude difference. The value A2 calculates and displays the first hardness index value and the second hardness index value. Therefore, the operator (for example, a medical staff or a test subject, etc.) only needs to apply pressure and quantity to the site B to be tested. The device for measuring the vibration amount of the portion B to be tested (such as the arterial wall hardness detecting device of the present invention) can evaluate the degree of arteriosclerosis by the difference in vibration amplitude, which can greatly reduce the equipment cost, and is widely used in medical institutions or The general family and other places are the effects of the present invention.

Furthermore, the present invention only needs to control the pressure-receiving module 1 and the measurement module 2 by the control module 3 by the measurement module 2, and automatically obtain the test. Calculating and displaying the first hardness index value and the second hardness index value by the reference amplitude difference A0 of the portion B, temporarily pressing the pressing portion P, obtaining the first amplitude difference A1 and the second amplitude difference A2 Therefore, the operator (for example, a medical staff or a test subject, etc.) only needs to apply pressure to the site B to be tested and measure the amount of vibration of the site B to be tested (such as the arterial wall of the present invention). The hardness detecting device can automatically measure the blood vessel hardness of the portion B to be tested, and easily obtain the first hardness index value and the second hardness index value for evaluating the hardness of the arterial blood vessel, thereby greatly reducing the difficulty of use, so that A well-trained person can also easily perform blood vessel hardness testing, which is an effect of the present invention.

In addition, the present invention provides an arterial tube wall hardness detecting device, which can temporarily compress the pressing portion P by the telescopic member 11 of the pressing module 1, and the sensing member 21 of the measuring module 2 is in contact with the human body to be tested. The portion B is used to measure the vibration amplitude of the soft tissue after being pressed by the force, and the data processing unit 31 of the control module 3 calculates the first hardness index value and the second hardness index value of the portion B to be tested, and displays The interface unit 32 of the control module 3 allows the operator to assess the degree of arteriosclerosis. Therefore, the arterial wall hardness detecting device of the present invention only needs to be composed of the telescopic member 11, the sensing member 21, the data processing unit 31, the interface unit 32, etc., and has the advantages of simple structure and easy acquisition of the purchase, and the like. The equipment cost is greatly reduced, and it is widely used in medical institutions or general homes and the like, and is an effect of the present invention.

While the invention has been described in connection with the preferred embodiments described above, it is not intended to limit the scope of the invention. The technical scope of the invention is protected, and therefore the scope of the invention is defined by the scope of the appended claims.

[this invention]

1. . . Pressure module

11. . . Telescopic member

111. . . Pressing end

12. . . Ontology

121. . . Base

122. . . Vertical positioning member

123. . . Horizontal positioning member

2. . . Measurement module

twenty one. . . Sensing piece

211. . . Sensing end

212. . . Vertical adjustment hole

twenty two. . . Joint piece

221. . . Horizontal adjustment hole

3. . . Control module

31. . . Data processing unit

32. . . Interface unit

33. . . Signal processing unit

A0. . . Reference amplitude difference

A1. . . First amplitude difference

A2. . . Second amplitude difference

B. . . Part to be tested

P. . . Pressure part

T. . . Pressure time

S1. . . Preparation step

S2. . . First measurement step

S3. . . Pressure step

S4. . . Second measurement step

S5. . . calculation steps

S6. . . Display step

Fig. 1 is a schematic view showing the system of the preferred embodiment of the arterial wall hardness detecting method of the present invention.

Figure 2: Side view of the combination of Figure 1.

Fig. 3 is a flow chart showing a preferred embodiment of the method for detecting the hardness of an arterial wall of the present invention.

Fig. 4 is a schematic view showing the use of the preferred embodiment of the arterial wall hardness test method of the present invention (I).

Fig. 5 is a schematic view showing the amplitude difference of the preferred embodiment of the arterial wall hardness detecting method of the present invention.

Fig. 6 is a schematic view showing the use of the preferred embodiment of the arterial wall hardness test method of the present invention (2).

S1. . . Preparation step

S2. . . First measurement step

S3. . . Pressure step

S4. . . Second measurement step

S5. . . calculation steps

S6. . . Display step

Claims (10)

A method for testing the hardness of an arterial wall includes: a preparation step of a measurement module colliding with a portion to be tested; and a first measurement step for measuring the vibration of the portion to be tested by the measurement module And outputting a vibration sensing signal to a control module. After the control module obtains a reference amplitude difference according to the amplitude of the vibration sensing signal, the control module outputs a first pressure signal; The step of driving the pressure applying module by applying the pressure signal to apply pressure to a pressing portion, and after a pressing time, the control module outputs a stop pressure signal to the Pressing the module to stop applying pressure to the pressing portion; and a second measuring step, the control module inputs the vibration sensing signal of the measuring module, and outputs the stop After the signal is applied, a first amplitude difference and a second amplitude difference are obtained according to the amplitude of the vibration sensing signal. In a calculating step, the first amplitude difference and the second are respectively calculated by the control module. The ratio of the amplitude difference to the reference amplitude difference, Generating a first hardness value and a second index hardness index value; and a display step of displaying the first hardness index-based value and the second hardness index value by the control module. The method for detecting an arterial wall hardness according to claim 1, wherein the control module calculates the first hardness index value as follows: Wherein R1 is the first hardness index value, A1 is the first amplitude difference value, and A0 is the reference amplitude difference value. The method for detecting an arterial wall hardness according to claim 1, wherein the control module calculates the second hardness index value as follows: Wherein R2 is the second hardness index value, A2 is the second amplitude difference value, and A0 is the reference amplitude difference value. The method for detecting an arterial wall hardness according to claim 1, wherein the pressing time ranges from 0.5 to 3 seconds. The method for detecting an arterial wall hardness according to the first aspect of the invention, wherein the part to be tested is a soft tissue appearance of a blood vessel of a human body. The arterial wall hardness testing method according to claim 1, wherein the pressing portion is a soft tissue appearance adjacent to the portion to be tested. The arterial tube wall hardness detecting method according to the first aspect of the invention, wherein the pressure applying module is pressed against the pressing portion by a telescopic member, and the measuring module obtains the reference amplitude difference from a sensing member. The control module has a data processing unit and an interface unit. The data processing unit is electrically connected to the interface unit, the telescopic member and the sensing member, and outputs the first hardness index value and the second hardness index value. To the interface unit. An arterial tube wall hardness detecting device comprises: a pressure applying module, which is disposed on a body by a telescopic member, the telescopic member has a linearly reciprocating pressing end; and a measuring module is provided with a sensing The sensing unit has a sensing end; and a control module is provided with a data processing unit and an interface unit. The data processing unit is electrically connected to the interface unit, the telescopic member and the sensing member. The arterial wall hardness detecting device according to claim 8, wherein the body is provided with a base, a vertical positioning member and a horizontal positioning member, and the vertical positioning member is coupled to the base in a lifting manner, the horizontal positioning The member is translatably coupled to the vertical positioning member, and the horizontal positioning member is fixedly coupled to the telescopic member. The arterial tube wall hardness detecting device according to claim 8 or 9, wherein the measuring module is further provided with a coupling member, and one end of the coupling member is provided with a horizontal adjusting hole combined with the body, the coupling member The other end is combined with one of the vertical adjustment holes of the sensing member.