TW201300101A - Forming device and method of medicine releasing hole on controlled release tablet - Google Patents

Abstract

The present invention relates to a forming device and a forming method of a medicine releasing hole on a controlled release tablet. The device includes a feeding device for outputting tablets, and a machine for forming a medicine releasing hole; in which the tablets can be detected and identified by a material detecting device, followed by a synchrotron, a resistance plate, and a tablet guiding and adjusting device so as to ensure the tablets to be kept a certain interval before delivered to a conveying device on the machine. After being detected and identified by the detecting device, the qualified tablets continue to be delivered to a laser punching device for forming medicine releasing holes. Then the tablets are detected and identified to be qualified by a detecting device. The qualified tablets are discharged by a guiding cylinder at an end of the conveying device, such that a purpose of automatically forming medicine releasing holes on a controlled release tablet can be achieved. Meanwhile, the present invention can be utilized in counting tablets, screening tablet points, screening printed marks on tablets, etc.

Description

Sustained release tablet release hole forming device and method

The invention provides a technical field of sustained release drug release orifice molding, in particular to a main technically provided device and method for releasing a sustained release drug tablet release hole, which can detect the ingot state multiple times and can strike laser Holes, in order to achieve the purpose of automatic molding release hole and counting drug ingot, sputum inspection drug stain, sputum inspection tablet printing mark, etc.

According to the sustained release tablet, it refers to a tablet which can continuously release the drug for a long time after administration to achieve a long-acting effect. That is, the sustained release tablet can continuously release the drug for a long time after the administration to achieve the purpose of prolonging the effect. The sustained-release drug tablet refers to a drug tablet which is superior to the common drug tablet, has a long-lasting drug treatment effect, has low side effects, and has a reduced number of administrations. Due to the design requirements of the tablet, the drug can be slowly released into the human body, and the fluctuation of the blood concentration "peak and valley" is small, which can avoid the side effects exceeding the therapeutic blood concentration range, and can be maintained within the effective concentration range to maintain the therapeutic effect.

The sustained release tablets have various types, one of which is that the tablet has a release hole, and the drug can be continuously and stably released from the release hole.

However, the molding of the sustained-release tablet is now possible, although the preparation of the tablet can be completed, but the most important release hole production is still unable to achieve the purpose of automation, and if it is made by manpower, it is too costly, and Processing quality is also difficult to control, so there is still room for improvement and improvement.

Therefore, in view of the problems existing in the above-mentioned conventional structure, how to develop an innovative structure that is more ideal and practical, the consumers are eagerly awaiting, and the relevant industry must strive to develop the goal and direction of breakthrough.

In view of this, the inventor has been engaged in the manufacturing development and design experience of related products for many years. After detailed design and careful evaluation, the inventor has finally obtained the practical invention.

The main object of the present invention is to provide a sustained release tablet release orifice forming device and method, comprising: a feeding device for outputting a tablet and a machine for forming a release orifice; wherein the tablet can be tested and identified by a discharge detecting device. After the medicine ingot is passed through the synchrotron, the resistance plate and the tablet guide adjuster, the medicine ingot is kept at a certain interval and then sent to the conveying device on the machine table, and after detecting the qualified medicine tablet by a front detecting device The laser hole punching device is continuously formed into a release hole, and the identified ingot is detected by a detecting device, and the qualified tablet is discharged from the guiding cylinder at the end of the conveying device to reach the fully automated sustained release tablet releasing hole. For the purpose of molding, the present invention can also be used for counting the effects of the ingot, the stain of the sputum, and the printing mark of the sputum.

The sustained release drug tablet release hole forming device disclosed in the present invention, wherein the laser drilling device has a sensing fiber (SENSOR) blocked by a tablet, when the tablet is sent by the conveying device to the laser drilling device , the laser gun output power of the laser punching device is triggered to be fixed on the surface of the tablet, and the discharge power is formed by the laser power reaching the surface of the ingot; the peripheral edge of the laser beam is provided with a hollow punching hole. The collecting hood and the collecting hood are connected with an exhaust fan to form a negative pressure on the periphery of the laser beam exit. When the laser hits the surface of the tablet, the high temperature will burn the ingot and generate smoke, and the laser beam exits the peripheral negative pressure environment. The smoke will be concentrated and discharged.

The invention discloses a sustained release drug tablet release hole forming device, wherein the detecting device comprises an interrupting induction optical fiber (SENSOR), a CCD image identifier and a high pressure air spray gun, and the medicine tablet can be blocked by the sensing fiber ( SENSOR) triggers the CCD image recognizer to detect the qualified ingots, and the ingots with the wrong front and back sides, the punching position and the number of punched holes are excluded by the high-pressure air spray gun, and the qualified ingots are continuously guided by the end of the conveying device. The cylinder is discharged.

The invention relates to a sustained release tablet release orifice forming device, wherein the feeding device comprises a receiving hopper and a rotating disc, the receiving hopper is provided with an outlet, and the outlet is provided with an adjusting plate for changing the size of the outlet, the adjusting The plate can be connected through a adjusting hole, and a certain amount of the feeding conveyor belt is disposed at the outlet of the receiving hopper, and the quantitative feeding conveyor belt quantitatively transports the medicine ingot into the rotating disk, and the medicine ingot in the rotating disk is pressed against A guide bar is guided to the outermost edge of the turntable.

The above-mentioned objects, structures and features of the present invention will be described in detail with reference to the preferred embodiments of the present invention. .

The present invention provides a designer of a sustained release tablet release orifice forming device and method.

In order to enable the reviewing committee to have a better understanding and understanding of the purpose, features and functions of the present invention, the embodiments and the drawings are described in detail as follows: First, please refer to the first to third figures, the present invention provides a The device and method for releasing sustained release drug ingots comprises: a feeding device (10) for outputting a medicine ingot; and a machine table (20) disposed on one side of the feeding device (10), including a conveying device (21), a laser drilling device (22) and a detecting device (23) and a control computer (24); wherein: the conveying device (21) is disposed in front of the machine table (20) The medicine supply ingot is conveyed by the feeding device (10) and then conveyed by the conveying device (21); the laser drilling device (22) is disposed on the conveying device (21) of the machine table (20) for The ingot is outputted to the surface of the ingot by a laser gun output power, and the discharge power is reached by the laser power reaching the surface of the ingot; the detecting device (23) is disposed on the laser perforating hole After the device (22) is positioned, when the drug ingot is formed into the detecting device (23) by the conveying device (21), the tablet can be front and back, and the punching position is performed. The detection and identification of the number of punches; the control computer (24) is disposed on the machine table (20), thereby connecting and controlling the feeding device (10), the conveying device (21), and the laser drilling device (22) and the detecting device (23).

As shown in the fourth and fifth figures, the sustained release drug release orifice forming device disclosed in the present invention, wherein the laser perforating device (22) has a sensing fiber (SENSOR) (220) which is blocked by a tablet, and is used as a medicine. When the ingot is sent to the laser perforating device (22) by the conveying device (21), the laser beam (SENSOR) (220) is used to trigger the laser gun output power at a fixed position on the surface of the tablet to obtain the laser power. A venting hole is formed on the surface of the etched ingot, and a hood (221) is provided with a hollow punching hole at the periphery of the laser beam exit, and the hood (221) is connected with a ventilator (222) (such as the third As shown in the figure, a negative pressure is formed on the periphery of the laser beam exit. When the laser strikes the surface of the tablet, its high temperature will burn the tablet to generate smoke, and the negative pressure environment around the exit of the laser beam will concentrate and discharge the smoke.

As shown in the sixth figure, the sustained release drug release orifice forming device disclosed in the present invention, wherein the detecting device (23) comprises an interrupting induction fiber (SENSOR) (230), a CCD image identifier (231) and a high voltage. The air spray gun (232), the medicine tablet can trigger the CCD image recognizer (231) to detect and read the qualified medicine ingot by the SENSOR (230), and at the same time, the front and back sides are wrong, the punching position is The ingot of the number of holes is rejected by a high-pressure air spray gun (232) to remove the unqualified drug ingot into a collecting tank (25), and the qualified tablet is continued by the conveying device (21) The guiding cylinder (26) at the end is discharged (as shown in the seventh figure).

Referring to the fourth figure, the sustained release drug tablet release hole forming device disclosed in the present invention, wherein a front detecting device (27) can be further disposed before the laser punching device of the machine to advance the tablet For comparison and identification of front and back, offset and shape, the front detecting device (27) also includes an interrupting induction fiber (SENSOR) (270), a CCD image recognizer (271) and a high pressure air spray gun (272). The tablet can trigger the CCD image recognizer (271) to detect the qualified tablet by the SENSOR (270), and if the front and back are incorrect, offset or the shape is not acceptable, a tablet will be activated. The high-pressure air spray gun (272) removes the unqualified drug ingot into a collecting tank (28) with high-pressure air, and the qualified tablet is continuously conveyed by the conveying device (21) to the laser drilling device (22). Release hole.

As shown in the eighth figure, the sustained release tablet release orifice forming device disclosed in the present invention, wherein the feeding device (10) comprises a receiving hopper (11) and a rotating disc (12), the receiving hopper (11) is provided There is an outlet (110), and an adjusting plate (111) is disposed in the outlet (110) to change the size of the outlet (110). The adjusting plate (111) is connected by a pulling handle (113) through an adjusting hole (112). a hopper conveyor (114) is disposed at the outlet (110) of the hopper (11), and the quantitative conveyor belt (114) quantitatively transports the medicine tablet into the rotary disk (12), the rotary disk ( The medicine ingot in 12) is guided to a outermost edge of the rotary disk (12) by a guide rod (121), and a rotary detecting device (13) is further disposed on the rotary disk (12). When the tablet is transferred to the discharge detecting device (13), the CCD image recognizer (131) is triggered by a snagging sensing fiber (SENSOR) (not shown) to detect the qualified tablet, and the defective product is composed of a high-pressure air. The spray gun (not shown) sprays high-pressure air to the rotary disc (12) for transport.

Please refer to the first and second figures, the sustained release drug release orifice forming device disclosed in the present invention, wherein the feeding device (10) and the machine table (20) further comprise a synchrotron (30), the synchronization The accelerator (30) is provided with two slide plates (31) for adjusting the gap to connect the outlet of the rotary disk (12) of the feeding device (10) with the front end of the conveying device (21) of the machine table (20), and the medicine tablet enters and transports A resistance plate (32) is arranged at the end of the slide plate (31) in front of the device (21), and the tablet is temporarily stopped by the resistance plate (32), and the subsequent tablet increases the forward thrust through the synchrotron (30). The frontmost medicine tablet is separated from the resistance plate (32) and enters the conveying device (21), and the subsequent tablet is required to wait for the next thrust enough to break the resistance plate (32) again to maintain the ingot At a certain interval, the tablet can be adjusted in speed by the synchrotron (30) to synchronize with the transport device (21).

In the above, the sustained release drug release orifice forming device disclosed in the present invention, wherein a drag guide (33) is disposed behind the resistance plate (32) of the synchrotron (30) for the ingot The agent guiding adjuster (33) guides the tablet to the position in the conveying device (21).

In the above, the sustained release tablet release orifice forming device disclosed in the present invention, wherein the conveying device (21) is composed of two parallel conveyor belts in the embodiment, and is composed of a plurality of sets of rollers (210) The appropriate spacing is fixed in the fixed plates on both sides, and a set of rollers (210) at the end thereof are driven by a servo motor (211) at a stable rotational speed to drive the conveying device (21), and the other rollers (210) are centered. The bearing is freely rollable for supporting the conveying device (21), and the surface of the conveying device (21) is kept flat. Further, a set of elastic wheels (212) is disposed under the conveying device (21). The delivery device (21) can be maintained at a certain tension.

As shown in the ninth figure, the method for forming a sustained release drug release orifice of the present invention comprises at least the following steps:

a. The ingot is outputted from a feeding device to a machine;

b. transporting the ingot to a laser perforating device through the conveying device on the machine to form a release hole;

c. Complete the medicine ingot of the release hole and then pass the identification of the medicine ingot on the machine, and the unqualified medicine ingot is removed by a high-pressure air spray gun;

d. The qualified tablet is continuously discharged from the end of the delivery device.

As shown in the tenth figure, the method for forming a sustained release drug release orifice according to the present invention, wherein a step of the front detection device is further provided before the step of forming the release orifice by the laser drilling device, the steps are as follows:

a. The ingot is outputted from a feeding device to a machine;

b. The tablet is qualified by a pre-detection device, and the unqualified tablet is removed by a high-pressure air spray gun;

c. then transporting the ingot to a laser perforating device through the conveying device on the machine to form a release hole;

d. Complete the medicine ingot of the release hole and then pass the identification of the medicine ingot on the machine, and remove the unqualified medicine ingot by a high-pressure air spray gun;

e. Qualified tablets continue to be discharged from the end of the delivery device.

It can be seen from the above that the device and method for releasing the drug release hole of the sustained release tablet of the present invention are indeed the first in the industry and meet the novel requirements of the invention patent, and the comprehensive innovative design conforms to the progressive requirements of the invention patent. And its fully automated laser-forming release orifices are in line with better industrial availability.

The present invention has been described with reference to the preferred embodiments of the present invention. However, those skilled in the art can change and modify the present invention without departing from the spirit and scope of the invention. Such changes and modifications shall be covered in the scope defined by the following patent application.

In summary, the present invention provides a sustained release tablet release orifice forming device and method, which have indeed achieved all of the objects of the present invention, and the spatial pattern of the combined structure is not found in the same product, nor has it been disclosed in the application. Before, and the present invention can be used for counting drug ingots, sputum inspection drug stains, etc., has complied with the provisions of the Patent Law, and applied in accordance with the law.

(10). . . Feeding device

(11). . . Feed hopper

(12). . . Back turntable

(110). . . Export

(111). . . Adjustment board

(112). . . Adjustment hole

(113). . . Pull handle

(114). . . Quantitative blanking conveyor belt

(121). . . Guide rod

(13). . . Discharge detection device

(131). . . CCD image recognizer

(20). . . Machine

(twenty one). . . Conveyor

(210). . . Wheel

(211). . . Servo motor

(212). . . Flexible wheel

(twenty two). . . Laser drilling device

(220). . . Interruption sensing fiber (SENSOR)

(221). . . Cigarette cover

(222). . . Extractor

(twenty three). . . Testing device

(230). . . Interruption sensing fiber (SENSOR)

(231). . . CCD image recognizer

(232). . . High pressure air spray gun

(twenty four). . . Control computer

(25). . . Collection tank

(26). . . Guide cylinder

(27). . . Front detection device

(270). . . Interruption sensing fiber (SENSOR)

(271). . . CCD image recognizer

(272). . . High pressure air spray gun

(28). . . Collection tank

(30). . . Synchrotron

(31). . . skateboard

(32). . . Resistance plate

(33). . . Lozenner guide adjuster

First Figure: is a schematic plan view of an embodiment of the present invention.

Second Figure: is a top plan view of an embodiment of the present invention.

Third Figure: is a partial cross-sectional side view of an embodiment of the present invention.

The fourth figure is a perspective view of the laser drilling device and the front detecting device of the present invention.

Figure 5 is a partial perspective view of the laser drilling device of the present invention.

Figure 6 is a perspective view of the detecting device of the present invention.

Figure 7 is a perspective view of the end of the delivery device of the present invention.

Figure 8 is a partial perspective view of the feeding device of the present invention.

Fig. 9 is a flow chart showing a method for forming a release orifice of a sustained release tablet of the present invention.

Fig. 10 is another flow chart showing the method for forming the release orifice of the sustained release tablet of the present invention.

(10). . . Feeding device

(11). . . Feed hopper

(110). . . Export

(111). . . Adjustment board

(112). . . Adjustment hole

(113). . . Pull handle

(114). . . Quantitative blanking conveyor belt

(12). . . Back turntable

(13). . . Discharge detection device

(131). . . CCD image recognizer

(20). . . Machine

(twenty one). . . Conveyor

(210). . . Wheel

(211). . . Servo motor

(212). . . Flexible wheel

(twenty two). . . Laser drilling device

(twenty three). . . Testing device

(twenty four). . . Control computer

(27). . . Front detection device

(30). . . Synchrotron

(31). . . skateboard

(32). . . Resistance plate

(33). . . Lozenner guide adjuster

Claims (13)

A sustained release drug tablet release hole forming device comprises: a feeding device for outputting a medicine ingot; and a machine platform disposed at a rear end of the feeding device, comprising at least one conveying device and a laser drilling device; a detecting device and a control computer; wherein: the conveying device is disposed in front of the machine table, and the medicine ingot is delivered by the feeding device after being discharged by the feeding device; the laser drilling device is set on the machine table On one side of the conveying device, the medicine ingot is outputted to the surface of the tablet by a laser gun output power, and the discharge power is reached by the laser power to form a discharge hole; the detecting device is disposed at the side After the laser punching device is in the rear position, when the medicine ingot is formed into the detecting device by the conveying device, the positive and negative surfaces, the punching position and the number of punching holes can be detected and interpreted; The control computer is disposed on the machine to control the feeding device, the conveying device, the laser drilling device and the detecting device. The slow release drug release orifice forming device according to claim 1, wherein the laser drilling device has a sensing fiber (SENSOR) which is blocked by a tablet, and the tablet is sent to the mine by the conveying device. When the hole punching device is used, the output power of the laser gun of the laser punching device is triggered to be fixed on the surface of the tablet, and the discharge power is formed by the laser power reaching the surface of the ingot; the periphery of the laser beam exit is set. The hood is provided with a hollow punching hole, and the hood is connected with an exhaust fan to form a negative pressure on the periphery of the laser beam exit. When the laser strikes the surface of the tablet, the high temperature will burn the tablet to generate smoke, and the laser beam The negative pressure environment around the outlet will concentrate and discharge the smoke. The sustained-release tablet release hole forming device according to claim 1, wherein the detecting device comprises a snagging induction fiber (SENSOR), a CCD image identifier and a high-pressure air lance, wherein the tablet can be used The snubber-inductive fiber (SENSOR) triggers the CCD image recognizer to detect and interpret the drug ingot. If the front and back are not correct, the punching position, and the number of punched holes are not good, a high-pressure air spray gun is activated to remove the unqualified drug ingot by high-pressure air. In a collection tank, the qualified tablet is continuously discharged by the guide cylinder at the end of the conveyor. The slow release drug release orifice forming device according to claim 1, wherein a front detecting device can be further disposed before the laser punching device of the machine to make the front and back of the tablet in front and back. Move and shape the comparison and interpretation. The sustained release drug release orifice forming device according to claim 4, wherein the front detecting device comprises a snagging induction fiber (SENSOR), a CCD image identifier and a high pressure air lance, wherein the tablet can be used The snubber sensing fiber (SENSOR) triggers the CCD image identifier to detect and interpret the medicinal ingot. If the positive and negative sides are incorrect, offset or unqualified, the high pressure air lance is activated to remove the unqualified medicinal ingot. In a collection tank, the qualified tablet is continuously conveyed by the conveying device to the laser drilling device to form a release hole. The slow release tablet release orifice forming device of claim 1, wherein the feeding device comprises a receiving hopper and a rotating disc, the receiving hopper is provided with an outlet, and the outlet is provided with an adjusting plate to change the The size of the outlet is such that the adjusting plate is connected through a adjusting hole, and a certain amount of the feeding conveyor belt is disposed at the outlet of the receiving hopper, and the quantitative feeding conveyor belt quantitatively transports the medicine ingot into the rotating disk, and the rotating plate is in the rotating plate The ingot is guided by a guide rod to the outermost edge of the rotating disc. The sustained-release tablet release hole forming device according to claim 6, wherein the rotary disk is provided with a discharge detecting device, and when the tablet is transferred to the discharge detecting device, an interrupting induction fiber is used. (SENSOR) triggers the CCD image recognizer to detect and interpret. The unqualified product is discharged from the high-pressure air by a high-pressure air spray gun and discharged to the rotary disk for transport. The slow release drug release orifice forming device according to claim 1, wherein the synchronous device is further provided with a synchrotron, and the synchrotron is provided with two slides for adjusting the gap. a rotating plate outlet of the device and a front end of the conveying device of the machine, and a resistance plate is arranged at the end of the sliding plate before the medicine tablet enters the conveying device, and the medicine tablet is temporarily stopped by the resistance plate, and the subsequent medicine tablet passes through the synchronous accelerator. Increasing the front thrust, so that the foremost medicine tablet is separated from the resistance plate and enters the conveying device, and the subsequent medicine tablet is required to wait for the next thrust enough to break the resistance plate again, so that the medicine tablets are kept at a certain interval, and at the same time The tablet can be adjusted to synchronize with the delivery device by the synchrotron. The sustained-release tablet release hole forming device according to claim 8, wherein a drag guide adjuster is disposed behind the resistance plate of the synchrotron to control the drug by the tablet guide adjuster The ingot is guided to the position in the middle of the conveying device. The sustained release tablet releasing hole forming device according to claim 1, wherein the conveying device is fixed to the fixing plates on both sides at an appropriate interval by a plurality of sets of rollers, and a set of rollers at the end thereof is The servo motor is driven at a stable rotational speed to drive the conveying device, and the other roller center is provided with a bearing that can freely roll to support the conveying device, and the surface of the conveying device is kept flat, and a set of the conveying device is arranged below the conveying device. The elastic wheel can maintain a certain tension of the conveying device. The sustained release tablet release orifice forming device according to claim 1, wherein the conveying device is composed of two parallel conveyor belts. A method for forming a sustained release drug release orifice comprises at least the following steps: a. the tablet is outputted from a feeding device to a machine; b. the tablet is conveyed to a laser through a conveying device on the machine The hole device forms a drug release hole; c. the drug tablet in which the drug release hole is completed and then passed through a detection device on the machine table, and the unqualified drug tablet is removed by a high-pressure air spray gun. The spindle is discharged from the end of the conveyor. The method for forming a sustained release drug release orifice according to claim 12, wherein a step of detecting the drug is provided before the step of forming the release hole by the laser drilling device to identify the qualified tablet. At the same time, the unqualified tablets are removed by a high pressure air spray gun.