TW201300093A - Cooling system for inducing diving reflex - Google Patents

Abstract

The invention relates to a cooling system for inducing diving reflex and protecting the central nervous system. The cooling system includes a coolant supply unit, a flow path control unit, a body temperature keeping device, a controller and an injection unit. The flow path control unit is connected with the coolant supply unit. The body temperature keeping device is connected with the coolant supply unit through the flow path control unit and has a head cooling bag. The controller is configured to regulate the flow path control unit and the injection unit according to received physiological signals including cerebral oxygen concentration and nasopharyngeal temperature. The injection unit is connected with the controller and the catheter. When in use, the coolant is drawn to the head cooling bag covering the patient's face to induce the diving reflex. At the same time, the coolant is also injected to the stomach through the oesophagus by the injection unit to reduce the stomach temperature. Accordingly, the invention can effectively induce the diving reflex and keep the temperature low to protect the central nervous system.

Description

Cooling system for inducing diving reflection

The present invention relates to a cooling system, and more particularly to a patient who can induce and maintain a dive reflex to protect against hypoxic brain damage, spinal cord injury or central nervous system damage.

Diving reflex is a mammalian physiological reaction, including humans also have this physiological reaction, mainly because the face is exposed to cold water, so that the individual will have slow heartbeat, decreased metabolic rate and oxygenated blood flow to the brain. Departments and the heart mainly maintain the phenomenon of surviving organs to slow down the physiological activities of animals, thereby protecting animals from damage caused by sudden changes in the environment. This phenomenon has been repeatedly proved to be better than those who are simmering in ice water. Compared with those who are simmering in warm water, those who are immersed in ice water have a better chance of recovery.

For patients with hypoxic brain damage, spinal cord injury, or central nervous system damage, the prior art does not simultaneously provide equipment that induces and maintains reflexes, especially the internal organs of the patient, and therefore In terms of suffering, there is an urgent need for an effective, economical and convenient device for inducing diving reflection.

It is a primary object of the present invention to provide a cooling system to induce submersible reflections and to effectively cool the central nervous system. The body temperature, the cooling liquid is supplied, and the liquid cooled by the pump is pumped, so that the head, the face, the neck and the trunk of the patient are embedded therein, and the cooled saline is sent to the disease through the injection unit. The affected stomach is used to provide an effective heat exchange rate and effectively reduce the body temperature of the patient to protect the central nervous system.

The cooling system for inducing diving reflection of the present invention comprises a coolant supply unit, a first-class road control unit, an integrated temperature holder, a controller and an injection unit.

The coolant supply unit is available for cooling and providing a liquid.

The flow path control unit is coupled to the coolant supply unit to draw liquid.

The body temperature holder is connected to the coolant supply unit through the flow path control unit, and has a head cooling bag, wherein the head cooling bag comprises a bag body, a water inlet and a water outlet, wherein the material of the bag body It is a heat conductive material and has a chamber for accommodating a liquid, and a chamber thereof is connected to the flow path control unit through the water inlet; the water inlet and the water outlet are also connected to the flow path control unit.

The controller is coupled to the flow path control unit and is capable of detecting the patient's nasal pharygeal temperature and cerebral oximetry.

The injection unit is coupled to the controller and includes a cooler, a conduit, and a flow control unit. The cooler is coupled to the control module of the controller and provides cooled brine. The catheter includes a top end, an input cavity, and an output cavity. One end of the input cavity is located at the top end of the catheter, and another opening is formed at the other end of the input cavity. One end of the output chamber is also located at the top end of the conduit, and the output chamber has a diameter of 1 cm and a through hole is formed at the other end of the output chamber. The flow control unit is coupled to the cooler and the conduit and can draw the cooled brine to the cooler.

In accordance with the present invention, the term "take" as used herein refers to a flow control system that pumps or recovers liquid.

In use, the outer surface of the head cooling bag is wrapped around the patient's head, and the catheter is inserted into the stomach to provide a cooled saline solution to reduce the body temperature of the patient. The controller can adjust the flow path control unit and the injection unit according to the signals returned by the nasal pharyngeal probe and the cerebral oximetry probe of the forehead. This cooling system can effectively induce the diving reflex by detecting the brain temperature disease by nasal temperature probe and cerebral oxygen probe without harming the patient.

An advantage of the present invention is that it provides a low temperature to protect the brain and spinal cord of the patient, not only to cool the face of the patient, but also to cool the brain, neck, back, torso, stomach, esophagus, aorta and heart. The present invention has the following three characteristics: (1) cooling the head, the neck and the trunk by external cooling water, (2) cooling the face by cooling water to induce diving reflection, and (3) transmitting through the interior by cooling. The esophagus-gastric tube circulates to effectively cool the adjacent internal organs such as the heart, aorta, large veins, and liver, and the prior art cannot simultaneously monitor brain temperature (by nasal temperature probe) and cerebral oxygen concentration (in time, non- Invasive and continuous monitoring of cerebral oxygen content), the present invention more accurately controls the cooling process and appropriately and effectively induces submerged reflexes to protect the central nervous system compared to the prior art.

The cooling system for inducing diving reflection of the present invention, as shown in FIG. 1 and FIG. 2A, includes a coolant supply unit 10, a first-class road control unit 20, an integrated temperature holder 30, a controller 50A, and a Injection unit 70.

The coolant supply unit 10 is available for cooling a liquid, and the coolant supply unit 10 has a cooling water tank that can hold 15 gallons of water and cool it to 2 °C.

The flow path control unit 20 is connected to the coolant supply unit 10 for drawing the liquid in the coolant supply unit 10. The flow path control unit 20 has at least one pump 21, 22.

The body temperature holder 30 is connected to the coolant supply unit 10 through the flow path control unit 20 to constitute a first-class road, and the distribution and supply of the flow path is controlled by the flow path control unit 20, and the body temperature holder 30 is controlled. The utility model comprises a head cooling bag, a bag fixing seat 32 and a trunk cooling bag.

As shown in FIG. 3, the head cooling bag is coupled to the flow path control unit 20 and has a bag body 31 and at least one hose 34, 35. The bag body 31 can be made of a plastic material. Preferably, it is made of a transparent material for accommodating a liquid having a volume of about 20 liters and a size of about 100 cm square. The bag body 31 has a water inlet 311 and a water outlet 312. The water inlet 311 and the water outlet 312 are in communication with at least one of the pumps 21, 22 of the flow path control unit 20. The hoses 34, 35 are made of elastic material and are located in the bag body 31. The hoses 34, 35 are 1 inch in diameter and have an open end, a closed end and a plurality of water holes. The open ends of the hoses 34, 35 are in communication with one of the water inlet 311 or the water outlet 312, and the chamber of the bag body 31 passes through the water holes of the hoses 34, 35 and the water inlet 311 or the water outlet One of the 312 is connected.

The bag holder 32, as shown in FIG. 4 and FIG. 5, is made of a transparent plastic material (such as acrylic) for maintaining the shape of the bag body 31 so that the bag body 31 is covered with a disease. The affected face, the head and the neck have a box body 321 for accommodating a mammalian head, a first cover 322 and a second cover 323, wherein the case 321 has a top surface A front surface, a back surface, an opening 3211, a receiving slot, a top sliding slot 3212 and a side groove 3213. The opening 3211 is formed in front of the casing 321 and can communicate with the receiving groove. Two parallel sliding grooves 3212 are formed at the side of the top surface of the casing 321, and the first cover 322 is detachably inserted into the sliding groove 3212; two parallel side grooves are formed at the front side of the casing 321 The slot 3213 has a second cover 323 detachably inserted into the side groove 3213.

As shown in FIG. 6, the torso cooling bag is coupled to the flow path control unit 20 and has a bladder 33, at least one hose 36, 37, and a plurality of water holes. The pouch 33 is made of a plastic material and is made of a transparent material for accommodating a liquid having a volume of about 30 liters, a size of about 120 cm square, and having a water inlet 331 and a water outlet. The nozzle 332 and the two notches 333. The water inlet 331 is in communication with the water outlet 332 and at least one of the pumps 21, 22 of the flow path control unit 20. The two notches 333 are located on one side of the pouch 33. The hoses 36, 37 are of elastic material and are located on the other side of the bladder 33. Each of the hoses 36, 37 has a diameter of 1 inch, one end is closed and the other open end is connected to the water inlet 331 and the water outlet. At least one of the members 332 is in communication, and a plurality of water holes are formed in the hose, and the chamber of the bladder 33 communicates with one of the water inlet 331 or the water outlet 332 through the water holes of the hoses 36, 37. The securing member 38 is a velcro that can be secured to the pocket 33 in pairs and can thereby wrap the subject.

According to the present invention, the bag body 31 of the head cooling bag and the bag 33 of the trunk cooling bag are selected from the group consisting of plastic materials of the following group: polyethylene (PE), chlorinated polyethylene (CPE) ), nylon, polyamine (PA), polyethylene terephthalate (PET), or combinations thereof.

As shown in FIG. 7 , the controller 50A is connected to the coolant supply unit 10 , the flow path control unit 20 , and the injection unit 70 , and has a sensing module 40 , a control module 50 , and an input unit 60 .

The sensing module 40 is configured to detect a physiological message generated by a mammal and convert it into a signal and transmit the signal. The aforementioned information may be brain temperature, body temperature, blood oxygenation, brain oxygen content, and the like. In a preferred embodiment of the present invention, the sensing module 40 is selected from the group consisting of: a brain temperature monitor, a body temperature sensor, and a pulse blood oxygen meter. A pulse oximeter and a cerebral oximeter. In another preferred embodiment of the present invention, the sensing module 40 includes an infrared body thermometer. In another more preferred embodiment of the invention, the sensing module 40 has a nasal probe that measures the temperature of the nasal pharyngeal.

The control module 50 can receive the signal from the sensing module 40 and interpret the signal to drive the flow path control unit 20, thereby feeding the liquid of the coolant supply unit 10 to the bag body 31 of the head cooling bag. And/or the liquid in the bladder bag 33 of the trunk cooling bag or the bag 33 of the head cooling bag and/or the bladder 33 of the trunk cooling bag is withdrawn to the coolant supply unit 10. In a preferred embodiment, the control module 50 is coupled to the coolant supply unit 10 to reduce the coolant supply unit 10 to a desired liquid temperature. In a preferred embodiment, the control module 50 is provided with a preset temperature value.

The input unit 60 is connected to the control module 50 for setting a preset value of the control module 50.

Referring to FIG. 2A and FIG. 2B, the injection unit 70 is connected to the control module 50 of the controller 50A, and includes a cooler 71, a conduit 72 and a flow control unit 73. The cooler 71 is coupled to the control module 50 of the controller 50A and provides cooled brine. The conduit 72 includes a top end, an input chamber 75 and an output chamber 76. One end of the input chamber 75 is located at the top end of the conduit 72, and another opening 751 is formed at the other end of the input chamber 75, and the input chamber 75 has a diameter of 1 cm. One end of the output chamber 76 is also located at the top end of the conduit 72 and has a through hole 761 at a distance of 15 centimeters from the other end of the output chamber 76, and the output chamber 76 has a diameter of 1 cm. The flow control unit 73 is coupled to the cooler 71 and the conduit 72 and includes at least one pump 74 for drawing brine to the cooler 71.

In use, please refer to FIG. 1 , FIG. 2A and FIG. 5 , firstly covering the head of the head cooling bag 31 on the head of the patient, and exposing the mouth and nose to maintain the respiratory tract. The mouth of the bag holder 32 is sleeved outside the bag body 31 of the head cooling bag, and the neck of the patient can pass through the opening 3211 of the case body 321 . Then, the first cover body 322 and the second cover body 323 are respectively disposed at the top end 3212 of the case body 321 and the opening 3213; and the bag 33 of the trunk cooling bag is sleeved on the trunk of the patient, and the gap is 333 is passed through the arms of a patient and secured by a fixation element 38.

Referring to FIGS. 3 and 6, the flow path control unit 20 pumps the liquid cooled to 2 to 4 ° C via the coolant supply unit 10 through the water inlets 311, 331 into the hose 34 of the bag body 31 of the head cooling bag. 35 and the hoses 36, 37 of the bladder 33 of the trunk cooling bag, since one end of the hoses 34, 35, 36, 37 is closed, the liquid will pass along the hoses 34, 35, 36, 37 and pass The water holes thereon are evenly distributed into the bag body 31 or the bag 33. Furthermore, since the bag body 31 or the bag body 33 itself has moderate flexibility, it can be closely fitted to the shape of the patient's body surface, thereby increasing the area of heat exchange, thereby effectively achieving the diving reflection of the patient. . As shown in Fig. 2A, the catheter 72 of the infusion unit 70 can be inserted into the patient's mouth and deep into the stomach 50 cm from the tooth, and the pump 74 can cool the saline by the input chamber 75 and its opening 751. The speed of 2 liters per minute is drawn to the stomach, and the saline solution is recovered at the same speed by the through hole 761 of the output chamber 76.

In a preferred embodiment of the present invention, when the signal from the sensing module 40 is higher than a preset value, the control module 50 drives the flow path control unit 20 to pump the liquid of the coolant supply unit 10 to the head for cooling. The pockets 31 of the bag and/or the pockets 33 of the trunk cooling bag also drive the pump 74 of the injection unit 70 to pump the cooled saline to the stomach of the mammal. When the signal from the sensing module 40 is lower than the preset value, the driving flow path control unit 20 recovers the liquid in the bag body 31 of the head cooling bag and/or the bag 33 of the trunk cooling bag to the coolant. The supply unit 10 also drives the pump 74 of the injection unit 70 to recover the brine from the mammalian stomach back to the cooler 71.

In another preferred embodiment of the present invention, the temperature of the control module 50 is preset to 33 ° C. When the incoming signal (eg, brain temperature) is lower than a preset value, the control module 50 can be driven. The flow path control unit 20 reduces the flow rate of the cooling liquid into the bag body 31 of the head cooling bag and/or the bag 33 of the trunk cooling bag, or preferably, the bag of the head cooling bag. The cooled liquid in the bladder 31 of the body 31 and/or the torso cooling bag is recovered into the coolant supply unit 10. At the same time, the control module 50 also drives at least one pump 74 of the injection unit 70 to recover the saline solution in the stomach of the mammal. By this action, the mammal can accurately induce the diving reflection and stably maintain the low temperature.

With the above features of the cooling system, the user can adjust the coolant supply unit 10, the flow path control unit 20, and the injection unit 70 via the detection result of the sensing module 40 of the controller 50A, thereby inducing diving reflection and maintenance. Low temperature to protect the central nervous system to effectively achieve the expected clinical outcome of saving the patient's life and protecting the central nervous system.

The invention is further described by the above-described embodiments, and modifications and modifications may be made without departing from the scope of the invention.

10. . . Coolant supply unit

20. . . Flow control unit

21,22. . . Pump

30. . . Body temperature holder

31. . . Bag body

311. . . water inlet

312. . . Outlet

32. . . Bag holder

321. . . Box

3211. . . Opening

3212. . . Chute

3213. . . Trench

322. . . First cover

323. . . Second cover

33. . . Pouch

331. . . water inlet

332. . . Outlet

333. . . gap

34, 35, 36, 37. . . hose

38. . . Fixed component

40. . . Sensing module

50. . . Control module

50A. . . Controller

51A. . . Signal input

60. . . Input unit

70. . . Injection unit

71. . . Cooler

72. . . catheter

73. . . Flow control unit

74. . . Pump

75. . . Input cavity

751. . . Opening

76. . . Output cavity

761. . . Through hole

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic illustration of an embodiment of the invention.

Figure 2A is a schematic illustration of a preferred embodiment of the invention.

Figure 2B is a partial enlarged view of the present invention

Figure 3 is a top plan view of the head cooling bag of the present invention.

Figure 4 is a perspective view of the bag holder of the present invention.

Figure 5 is a side elevational view of the head cooling bag and bag holder of the present invention.

Figure 6 is a top plan view of the torso cooling bag of the present invention.

Figure 7 is a schematic diagram of circuit control of the cryopreservation system of the present invention.

30. . . Body temperature holder

31. . . Bag body

32. . . Bag holder

33. . . Pouch

50A. . . Controller

70. . . Injection unit

71. . . Cooler

72. . . catheter

73. . . Flow control unit

74. . . Pump

Claims (10)

A cooling system for inducing diving reflection includes: a coolant supply unit for accommodating and cooling a liquid; a first-class road control unit connected to the coolant supply unit and capable of drawing the cooling a liquid in the liquid supply unit; an integral temperature holder connected to the coolant passing unit through the flow path control unit, and comprising: a head cooling bag, comprising: a bag body, comprising: a The bag cavity is adapted to receive a liquid; and a water inlet and a water outlet, wherein the water inlet and the water outlet are connected to the flow path control unit; and a bag body fixed seat has a space for receiving a box of a mammalian head, wherein one side of the box body has an opening through which the patient's neck passes; a controller connected to the flow path control unit to receive physiological signals from the mammal; and an injection unit And connected to the controller, comprising: a cooler connected to the controller and capable of cooling the brine; a conduit comprising a top end; an input cavity, one end of the input cavity being located at the top of the catheter And an opening is formed at the other end of the input cavity; and an output cavity, one end of the output cavity is located at the top end of the conduit, and a through hole is formed at a distance from the end of the output cavity; a flow control unit is coupled to The conduit and the cooler are connected and include at least one pump for drawing brine to the cooler. The cooling system for inducing diving reflection according to claim 1, wherein the head cooling bag has at least one hose in the bag body, and the hose is located in the pocket of the cooling bag body and is connected to the water inlet. Passing, and a plurality of water holes are formed on the hose. The cooling system for inducing submersible reflection according to claim 1, further comprising a torso cooling bag connected to the flow path control unit, comprising: a pouch comprising: a capsule The utility model relates to a liquid inlet and a water outlet, wherein the water inlet and the water outlet are connected to the flow path control unit, and a plurality of fixing elements can fix the bag. The cooling system for inducing a dive reflection according to claim 3, comprising at least one hose located in a cavity of the cooling bag and communicating with a water inlet of the bag, and A plurality of water holes are formed in the hose. The cooling system for inducing diving reflection according to claim 1, wherein the controller comprises: a sensing module capable of detecting a message generated by a mammal and converting the signal into a signal; A control module can receive the signal from the sensing module and interpret the signal to drive the flow control unit. The cooling system for inducing diving reflection according to claim 5, wherein the control module is provided with a preset value, and when the signal from the sensing module is higher than a preset value, the control module is The driving flow path control unit draws the liquid of the coolant supply unit into the head cooling bag and/or the trunk cooling bag, and drives the flow path control unit in the injection unit to draw the brine of the cooling liquid into the stomach of the mammal. The cooling system for inducing diving reflection according to claim 5, wherein the control module further has an input unit, wherein the input unit is configured to set a preset value of the control module. The cooling system for inducing diving reflection according to claim 5, wherein the sensing module is selected from the group consisting of: a brain temperature monitor, a body temperature sensor, and a pulse blood. A pulse oximeter and a cerebral oximeter. The cooling system for inducing a dive reflex according to claim 5, wherein the sensing module comprises a nasal probe, the nasal probe can measure a nasal pharyngeal temperature. The cooling system for inducing diving reflection according to claim 3, wherein the controller comprises: a sensing module capable of detecting a message generated by a mammal and converting the signal into a signal, wherein The sensing module is selected from the group consisting of a brain temperature monitor, a body temperature sensor, a pulse oximeter, and a cerebral oximeter; the sensing The module further includes a nasal probe, the nasal probe can measure the temperature of the nasal pharyngeal; and a control module that can receive the signal from the sensing module and interpret the signal to drive the flow path a control unit; wherein the control module is provided with a preset value, and when the signal from the sensing module is higher than a preset value, the control module drives the flow path control unit to draw the liquid of the coolant supply unit to the head Cooling the bag and/or the body cooling bag, and driving the flow path control unit in the injection unit to extract the brine of the coolant into the stomach of the mammal; the control module further has an input unit, the input unit is settable The control module default value.