TW201228633A - Physiological detecting device and system - Google Patents

Abstract

The present invention provides a physiological detecting device comprising a photo-emitter, a photo-detector, an analog signal conditioner, and a microcontroller. After the photo-emitter alternatively emits an infrared beam, and a red light beam to an organism, the photo-detector receives the infrared beam and the red light beam from the organism and generates an infrared signal and a red light signal, respectively. After the infrared signal and the red light signal are processed by the analog signal conditioner, according to these signals, the microcontroller calculates the physiological parameters.

Description

201228633 VI. Description of the Invention: The present invention relates to a physiological detecting device and a system thereof, and more particularly to a physiological detecting device using a photoplethysmography (PPG) and a system thereof. [Prior Art]

The socialization of Taiwanese society has also resulted in considerable medical resources. The current medical tests are mostly completed in medical institutions, which not only increases the time for patients to travel back, but also wastes a lot of social resources. At present, although the oximeter is quite common in major hospitals and clinics, it can only provide on-site measurement. It is impossible for hospitals, clinics or general users to keep abreast of the blood oxygen concentration data of the subjects for long-term body inclusion. Oxygen status monitoring. According to the study report, long-term tissue hypoxia leads to heart and brain defects and prolongs wound healing time. Especially in middle-aged and elderly patients with diseases, long-term lack of oxygen will lead to a sharp deterioration of bodily functions. In view of this, 7' monitoring of long-term physical oxygen conditions is very important. The general oximeter itself is large in size and needs to be equipped with a certain volume of weight: it can provide the power required for the micro-processing and display unit, which will cause the volume and weight of the oximeter to increase. The cost of the oxygen machine itself increases. With the advancement of technology, how to reduce the components of the measuring device when the goal is revealed and scorned, but the basic function of the word becomes an important lesson. In addition, the convenience of use is difficult. The availability of data after the use of the 1st king of the people is also..., ° again. One of the factors to consider when measuring the device. In addition, the conventional oximeter can provide a limited number of sputum, most of the 201228633 oximeter can only provide blood oxygen concentration (Sp 〇 2) and pulse rate. Therefore, it is not possible to regularly collect other important physiological parameters for a specific disease, such as perfusion index (ΡΙ), respiration rate (respirat〇ry rate), pulse reflex index (RI), and vascular sclerosis index (stiffness). Index, si) and other clinically important physiological parameters. In addition, the traditional oximeter cannot provide similar TCM pulse diagnosis based on the above physiological parameters because it cannot provide the above other clinically important physiological parameters.

Harmonic analysis, at the same time, can not further understand the human body's internal organs and the degree of harmonious resonance of the system, for the scientific basis of TCM syndrome differentiation. SUMMARY OF THE INVENTION The present invention provides a physiological detecting device that measures an amount of blood volume change by an optical method of photoplethysmography. Since the physiological detecting device of the present invention uses an optical device for measurement, the present invention is effective. The device reduces the volume of the device and reduces the weight for the user to measure at any time. Because of this, Ming's microcontroller can calculate many clinically important physiological parameters by analyzing infrared light signals and red light signals, and this wave can also provide waveform analysis similar to traditional Chinese medicine pulse diagnosis. The scientific basis for the treatment of symptoms. In order to achieve the above (4), the present invention discloses a physiological detecting device comprising a light emitter, a light sensor, an analog signal processor and a micro controller. After the light emitters mutually transmit the infrared beam and the red light beam to the living body, the light sensor receives the infrared light beam and the red light beam reflected or transmitted from the biological body to generate an infrared light signal and - Red light signal. The analog signal processor processes the infrared light t« and the red light signal, 201228633 and separates one of the infrared light signals from the direct current signal and one of the infrared light signals, and separates one of the red light signals from the direct current signal and the One of the red light signals is an alternating current signal. The microcontroller controls the light emitter to emit the infrared light beam and the red light beam, and the microcontroller uses the DC signal of the infrared light signal and the alternating current signal and the direct current signal of the red light signal and the alternating current signal Estimate physiological parameters. The invention discloses a physiological detection system comprising a physiological detecting device, a computer and a data capturing unit. The physiological detecting device comprises a light emitter, a light sensor, a analog signal processor and a microcontroller. After the microcontroller controls the light emitter to mutually transmit an infrared light beam and a red light beam to a living body, the light sensor receives the infrared light beam and the red light beam reflected or transmitted from the living body to generate a Infrared light signal and a red light signal. Then, the analog signal processor processes the infrared light signal and the 3 Xuanhong optical signal 5 tiger' and separates one of the infrared light signals and one of the infrared signals of the infrared light signal, and the analog signal processor is also separated. One of the red light signals is an alternating current signal and one of the red light signals is an electrical signal. The microcontroller pushes the nasal physiological parameters by the DC signal of the infrared light signal, the DC signal of the AC signal and the red signal, and the AC signal. After the data acquisition unit transmits the infrared light signals and the red light signals of the red light signals and the alternating current signals to the computer, the computer stores the infrared light signals and the direct current signals of the red light signals and the The electrical signals are exchanged, the physiological parameters are analyzed, and the physiological parameters are displayed in real time. [Embodiment] 201228633 In the following, embodiments of the present invention are described in conjunction with the accompanying drawings. The following examples are taken as a description of the invention, but the invention is not limited to the embodiments. That is, there are = mutually appropriate combinations between the various embodiments presented to achieve other embodiments. The "embodiment", "example embodiment", "various embodiments" and the like referred to in the specification are intended to encompass the particular features, constructions, or characteristics described in this embodiment of the invention. The phrase "in the examples" appearing throughout the specification does not necessarily refer to the same embodiment. Terms such as "filter", "reserved", "separate", "process", "control", "calculation", "conversion", "storage", "transfer", "transfer" or the like are used in the specification. Means the operation or processing of a computer or computer system, or a similar electronic computing device, which manipulates or transforms a temporary memory of a computer system or a physical (such as electronic) amount of data in a memory It becomes a similar material that is similar to the physical quantity in a computer system memory, scratchpad or other such information storage, transmission or display device. When the heart contracts and relaxes, the artery also contracts and relaxes, causing a periodic change in blood flow per unit area of the blood vessel. When the blood volume changes, when measured by optical measurement, the sensed light intensity also changes with the volume of the blood. The amplitude of the resulting signal changes proportionally with the flow of blood into and out of the tissue, just like an alternating component. The optical signal waveform that receives such changes in blood volume over time and in the tissue is called a photoplethysmography (PPG) signal, and the non-invasive physiological detecting device uses the PPG signal to analyze cardiovascular parameters. As shown in Figure 1A, the waveform of the PPG signal usually has two peaks. The first peak of 201228633 is the measurement part of the organism directly along the path of the aorta (such as a finger). The second peak is transmitted to the second peak. After the lower part of the body, the signal reflected by the bloodstream from the peripheral blood to the heart is shown in Figure B. As shown in Figure 2, in addition to the physiological component of the AC component (AC component) that changes with the change in blood volume, the PPG signal also contains venous blood, tissue blood, and non-pulse blood. The DC portion of the changed blood volume (DC component). Referring to the embodiment of Fig. 3, Fig. 3 is a view showing an embodiment of the physiological detecting device 1 of the present invention. The physiological detecting device 1A includes a light emitter 2A, a photo sensor 30, an analog signal processor 4', a microcontroller 5, and a display 60. Photoplethysmography (ppG) uses the optical side & measure the volume change of blood, t is a kind of non-invasive measurement of the blood flow through the tissue of the human finger. Physiological sensing technology. The non-invasive physiological sensing technology of the light emitter 2 and the light sensor 30 can be divided into two embodiments, such as the through-type detection mode shown in FIG. 4A and the reflective type as shown in FIG. 4B. Detection method. In the transmissive detection mode as shown in FIG. 4A, the light emitter 2 is disposed at the top end of the detecting organism (such as the finger 100), and the light emitter 2 includes a red diode 201 in this embodiment. An infrared photodiode 2〇2 and a driving circuit (not shown). The driving circuit is electrically coupled to the microcontroller 5 (in FIG. 3), and the microcontroller 50 controls the driving circuit to alternately drive the red diode 2〇1 and the infrared diode 202 to make the red diode 2 〇1 and infrared light diode 202 illuminate and turn off each other. (d) In other embodiments (not shown), the red LED 201 and the infrared diode 2〇2 may also be integrated into a single light 201228633 transmitter 20 (in FIG. 3), such a light emitter 2 The 〇 can alternately emit an infrared beam and a red light beam into a living body. Referring to FIG. 4A, a photo sensor 30 is disposed at the bottom of the finger i, and the photo sensor 3 includes a light receiving diode 3〇1 and a current converting voltage circuit (not shown), and the light receiving diode 3 The 〇1 receives the infrared light beam and the red light beam transmitted from the finger 100, and respectively generates a current, and the current-to-voltage circuit (not shown) generates the infrared light signal and the red light according to the current conversion. Signal. In the reflective detection mode shown in FIG. 4B, the light emitter 2 is disposed at the top end of the detected organism (eg, skin n〇), and the light emitter 20 includes a red diode 20 in this embodiment. Bu-infrared diode 202 and a driving circuit (not shown). The driving circuit electrically couples the microcontroller 50 (in FIG. 3), and the microcontroller 50 controls the driving circuit to alternately drive the red diode 201 and the infrared diode 202, and the red diode 20 1 and the infrared The light diodes 202 are illuminated and turned off each other. Referring to FIG. 4B, the photo sensor 30 is disposed at the top end of the skin 丨10 and adjacent to the light emission illuminator 20, and the photo sensor 3 〇 includes a light receiving diode 3〇1 and a current transfer electric circuit (not shown). The light receiving diode 301 receives the infrared light beam reflected from the skin 11 及 and the red light beam ′ respectively to generate at least one current, and the current converting voltage circuit (not shown) generates the infrared light signal according to the current conversion. The red light signal. The principle of photoplethysmography is similar to the principle of pulse wave. The principle of photoplethysmography uses a specific light source, such as infrared light diode 202 with a spectral wavelength of 930~950 nm (preferably 940 nm), or using spectrum. A red light diode 2 (H, having a wavelength of 650 to 670 nm (preferably 660 nm), is used as input light to penetrate into skin tissue or other tissues, and then receives a reflection or transmission using a photosensor 30 201228633 The infrared light beam and the red light beam. Referring to FIG. 3, the physiological detecting device 1 further includes an analog multiplexer 70'. The analog multiplexer 70 electrically couples the light sensor 30 and can be separated by the light sensor. 30. The infrared signal IR and the red signal R are generated for input to the analog signal processor 40. When the infrared signal IR and the red signal R are transmitted to the analog signal processor 4, the analog signal processor 40 can process The infrared signal IR and the red signal R separate the IR signal IR-DC of the infrared signal IR and the IR signal AC_AC of the infrared signal. The analog signal processor 40 can also separate the DC signal r_dC and red light of the red signal r. The AC signal R_AC of the number R. Specifically, the analog signal processor 40 includes a low pass filter circuit 401 and a band pass filter circuit 402. The low pass filter circuit 401 retains the DC signals IR_DC of the infrared light signal ir and the red light signal r. , R-DC, and filtering out the alternating current signals IR-AC, R_AC, and band-pass filter circuit 402 of the infrared light signal ir and the red light signal R, and retaining the alternating current signals IR of the infrared light signal IR and the red light signal r- AC, R-AC, and filtering out the DC signals IR-DC, R-DC of the infrared light signal IR and the red light signal r. One embodiment of the low-pass filter circuit 401 has a cutoff frequency range of 0.1 Hz to 1 〇. Between Hertz, and one of the bandpass filter circuits 402, the cutoff frequency range is between 1 Hz and 2 Hz. The four sets of electrical signals are individually transmitted to the microcontroller 5. The microcontroller 5 is removed. The main function of the microcontroller 50 can be controlled by the red light clock control signal CLK-R and the infrared light clock control sfl number CLK_IR controlling the light emitter 2 to mutually transmit the infrared light beam and the red light beam. Infrared light signal • 10- 201228 633 IR of the DC signal IR_DC and the AC signal IR-Ac and the red signal R of the DC signal R-DC and the AC signal r_ac to calculate a physiological parameter, and the display 60 can display the physiological parameter in real time. In terms of blood oxygen concentration, the blood oxygen concentration is expressed as the saturation degree of hemoglobin in the blood, and is generally measured by oxyhemoglobin (Hb〇2) and hemoglobin (Hb). The ratio of the oxygen concentration is Sp〇2, and the ratio of oxygenated hemoglobin to total heme is derived by using the indirect method.

Sp〇2 = -^_xl00% Formula i ^Hb02 ^ UHb where cHb〇2 indicates the concentration of oxygenated hemoglobin in the blood and cHb indicates the concentration of oxygen-free heme in the blood. The blood is basically composed of blood cells and plasma, and more than 990/0 of the blood cells are red blood cells, so the white blood cells have little effect on the physical properties of the blood. Lambert uses mathematical equations to express the relationship between absorbance and the medium' until Beer determines the relationship between absorbance and medium concentration, thus establishing the basic law of light absorbance, generally called

Beer-Lambert’s Law. According to this law, the absorption of light by matter is exponentially related to the concentration of light path and matter, as in Equation 2:

It=I〇.e,d Equation 2 where It represents the transmitted light intensity, I. Indicates incident light intensity, c indicates the concentration of the analyte, d indicates the length of the optical path, and ε indicates the light absorption coefficient of the substance. It can be seen from Equation 2 that the incident light intensity J is known. The concentration c of the analyte solution can be calculated from the transmitted light intensity It and the absorption coefficient ε and the optical path length d known as [S] -11 - 201228633. Re-defining the optical intensity (〇pticai density, OD) as shown in Equation 3: OD = Ιηγ = sxcxd Equation 3 Equation 3 is based on the assumption that the measurement conditions are constant (ie, ε and d are constant), then the optical intensity is known. The linear relationship of the concentration of the analyte. Thus, the unknown analyte concentration can be obtained from the magnitude of the optical intensity. The measurement of blood oxygen concentration is mainly based on Hb〇2 and Hb on the light absorption spectrum.

The difference 'is one wavelength of light (such as infrared light and red light) into the human tissue (usually the finger 100 ' as shown in Figure 4A), and the other end senses the transmitted light with the light sense strength. Another reason for choosing dual wavelengths is that it is extremely inconvenient to accurately measure the incident light and the reflected light intensity in practical applications, so the two-wavelength derivation is used to form a percentage form. The physiological detecting device 1 of the present invention is irradiated with red light r and infrared light IR respectively, and the OD of each of them can be obtained as follows: OD(R) = ^〇2 cm〇2 d+ ^. CHb. d Equation 4 〇 〇卿_ fHb〇2 CHb〇2.^ CRb · d Equation 5 where: Hb〇2 is the absorption coefficient of infrared light for oxygenated hemoglobin, cHb〇2 is expressed as the concentration of oxygenated heme, and black is expressed. The absorption coefficient of infrared light for non-hemoglobin, cHb is expressed as the concentration without oxygen hemoglobin, the absorption coefficient of oxygenated hemoglobin for red light, and ^ is the absorption of red light without oxygen hemoglobin. coefficient. Redefining the ratio of the light intensity of the solution (the ratio of change in absorbance to the amplitude of the photoelectric signal) Ros is as follows: m -12- 201228633

Ros=M 〇_ Equation 6 For adults, 1 940 nm infrared light and 66 〇 nm red light are taken as examples. The absorption coefficients of Hb for infrared light and red light are 〇2 and 〇86, respectively; = Hb〇2 pairs The absorption coefficients of infrared light and red light are ο.” and 〇12, respectively. The unit of absorption coefficient above is liter/mmol*cm. Substituting formula 4 and formula $ into equation 6 and then substituting into type 3 and Hb and cutting 2 pairs of infrared light and red light absorption coefficient ' can be obtained as follows:

Sp〇2 = —86"Q-2xRgL 0.74 +0.09xRos Equation 7

If the intensity of the absorbed light in the non-pulse portion of the arterial blood (as shown in Fig. 2) is combined with the absorbed light intensity of the venous blood and the tissue blood, the portion of the light intensity that does not change with the pulse and time can be regarded as a DC component (in the formula) Expressed by DC) 'However, if the portion of the light intensity that changes with changes in arterial pressure is defined as the AC component of the absorbed light intensity of the pulse arterial blood (indicated by AC in the formula)' then R〇s can be expressed as Equation 8:

Ros = ACr + DCr, OD(R) _ DCr ' DCir where ACR is represented by the AC signal R_AC processed by the microcontroller 50 shown in FIG. 3, and the corresponding DCr is the DC signal R_DC, and ACir is the AC signal. IR_AC and DC1r are DC signals IR_DC. Therefore, the microprocessor 50 can calculate the blood oxygen concentration sPo2 in the physiological parameters by Equations 7 and 8. Referring to the PPG signals shown in FIG. 1A, FIG. 1B and FIG. 5, the alternating currents [S] -13 - 201228633 electrical signals IR-AC, R-AC (shown in FIG. 3) comprise a plurality of unit pulse waves 200, The unit pulse wave 200 includes a first wave A, a second peak B, and two waves C, D. The vertical distance from the valley C to the first peak A is the first amplitude AM of the unit pulse wave 200. The ratio of the first amplitude eight rivers to the corresponding DC signal DC is defined as a perfusion index in the physiological parameters (perfusi〇n index ). The 彳 a 彳 indicates the ratio of the pulse amplitude AM to the direct current (DC) component in the ppg signal. Peripheral perfusion (peripheral perfusi (>n index, ρρι) is a change in peripheral blood flow. PPI can be used to predict changes in stroke volume caused by arterial circulation, but changes in PPI are subject to measurement and measurement. In addition, the perfusion index has a high recognition effect on symptoms such as proximal sympathectomy, pr〇ximal arteHal clamping, and neonatal left ventricular occlusion. Therefore, it can be used to predict Or diagnose the occurrence of these diseases. Furthermore, the pulse reflectance index (RI) and the sclerosing index (SI) have physiological parameters about vascular sclerosis. After recent studies, arteriosclerosis is the heart. Symptoms of pre-vessel disease are closely related to heart disease and cerebrovascular disease. As shown in Figure 5, in the ppG signal, the first peak A is the blood-powered wave connected to the finger along the path of the aorta. The second peak B is the dicr〇tic wave that is reflected back after the hemodynamic wave is transmitted to the lower half of the body, as shown in the figure and figure (7). As shown, the delay time from the first peak A to the second peak b is determined by the conduction time of the pulse back through the clavicular artery and back to the clavicular artery by the reflected wave. The distance of the conduction and the subject are assumed. The height of the body is proportional to the transmission time of the pulse in the aorta and aorta, 201228633. The parameters of the atherosclerosis index reflect large

The ratio of AM is the pulse reflectance index in the physiological parameters. Reflection index = can be used to calculate indicators of vascular sclerosis. The degree of hardening of the arteries, and the degree of contraction of the pulse reflex. Through the PPG signal name

Stiffiiess index Two ^^ ι.· 1Λ △t Equation 10 The parameters are shown in Figure 5: the delay between two peaks, AM is the amplitude of the first peak A, and DW is the amplitude of the second peak]b. As shown in FIG. 6, the present invention discloses a physiological testing system comprising a physiological detecting device 10, a data capturing unit 8 and a computer 9A. The physiological detecting device 10 includes a light emitter 20, a light sensor 3A, an analog signal processing 40 microcontroller 5A, and an analog multiplexer 70. After the light emitters 2 〇 mutually transmit the infrared light beam and the red light beam to the living body, the light sensor 3 〇 receives the infrared light beam reflected by or transmitted from the living body and the red light beam to generate an infrared light signal and a Red light signal. The analog multiplexer 7 is electrically coupled to the photo sensor 30 and can separate the infrared signal ir and the red signal r for input to the analog signal processor 40. The analog signal processor 40 includes a low pass filter circuit 401 and a band pass filter circuit 402. The analog signal processor 40 processes the infrared light signal IR and the red light signal R and separates the infrared light signal IR, a DC signal IR_DC, and the infrared signal. One of the optical signals IR -15- 201228633 signal IR_AC, separates the DC signal R-DC of the red signal R and the AC signal R_AC of the red signal R. The microcontroller 50 estimates a physiological parameter by the DC signal IR_DC of the infrared light signal IR and the alternating current signal iR Ac and the direct current signal IR_DC of the red light signal R and the alternating current signal R_AC. The data acquisition unit 80 transmits the DC signals IR-DC, R_DC and the AC signals IR_AC, R_AC of the infrared signal IR and the red signal R to the computer 90. The computer 90 stores the infrared light signals IR and the red light signals R of the DC signals IR-DC, R-DC and the alternating current signals IR-AC, R_AC, analyzes the physiological parameters and instantly displays the physiological parameters "and according to The alternating current signals IR-AC, R-AC segments in the above physiological parameters are segmented by, for example, two unit pulse waves 200 or three unit pulse waves 200, and then the Fourier transforms the segmented AC signals. And the average value obtained after averaging the Fourier transform values after segmentation is the pulse diagnosis judgment index. The pulse diagnosis index can provide similar wave analysis of TCM pulse diagnosis, and understand the information of the harmonious resonance degree of the human body's internal organs and the circulatory system, so as to provide scientific basis for TCM syndrome diagnosis. The technical contents and technical features of the present invention have been disclosed as above, and those skilled in the art can still make various substitutions and modifications without departing from the spirit and scope of the invention. Therefore, the scope of the present invention should be construed as being limited by the scope of the appended claims. [Simple diagram of the diagram] Figure ΙΑ, 1B is a schematic diagram of the generation mechanism of the PPG signal; • 16 - 201228633 Figure 2 is the signal distinction between the AC component (AC component) of the ppg signal and the DC component pc component; Figure 3 is a FIG. 4A is a schematic diagram of a light emitter and a light sensor according to an embodiment of the present invention; FIG. 4B is a schematic diagram of a light emitter and a light sensor according to another embodiment of the present invention; FIG. 5 is a schematic diagram of a first waveguide, a second peak, and two valleys in a unit pulse wave according to an embodiment of the present invention; and FIG. 6 is a schematic structural diagram of a physiological detection system according to an embodiment of the present invention. [Main component symbol description] 1〇 Physiological detection device 1〇| Physiological detection device 11 Physiological detection system 20 Light emitter 2〇1 Red light diode 2〇2 Infrared light diode 3 fluorescent sensor 3〇ι light Receiver diode 4〇 analog signal processor 4〇1 low pass wave circuit 402 band pass filter circuit 5〇microcontroller 201228633

60 Display 70 Analog multiplexer 80 Data capture unit 90 Computer 100 Finger 110 Skin 200 Unit pulse wave A First peak AM Young · One amplitude B Second peak DW Second two amplitude C, D Valley DC DC signal At Delay time IR Infrared light signal R red light signal IR_DC Infrared light signal DC signal IR_AC Infrared light signal AC signal R_DC Red light signal DC signal R_AC Red light signal AC signal -18- 201228633 CLK_R Red light clock control signal CLK IR infrared light Clock control signal

•19-

Claims (1)

201228633 VII. Patent application scope: 1 · A physiological detection device comprising: a light emitter that mutually emits an infrared beam and a red light beam to a living body; a light sensor received or reflected from the living body The infrared light beam and the red light beam respectively generate an infrared light signal and a red light signal; a analog signal processor processes the infrared light signal and the red light signal and separates one of the infrared light signals from the direct current signal and the infrared light a parent flow signal of the optical signal, separating one of the red light signal and one of the red light signals; and a microcontroller 'controlling the light emitter to emit the infrared light beam and the red light beam' The microcontroller estimates a physiological parameter by the DC signal of the infrared light signal and the alternating current signal and the direct current signal of the red light signal and the alternating current signal. 2. The physiological detection device of claim 1, further comprising an analog multiplexer electrically coupled to the optical sensor and separating the infrared light signal and the red light signal for inputting the analog signal processor. 3. The physiological detection device of claim 1, wherein the light emitter comprises a red LED, an infrared diode, and a driving circuit, the driving circuit is electrically coupled to the microcontroller, and the microcontroller controls the The driving circuit alternately drives the red LED and the infrared photodiode. 4. The physiological detecting device according to claim 1, wherein the photo sensor comprises a light receiving diode and a current converting voltage circuit, the light receiving diode receiving the infrared light beam reflected or transmitted from the living body and The red light beam, and -20-201228633 respectively generates at least one current. The current converting voltage circuit generates the infrared light signal and the red light signal according to the current conversion. 5. The physiological detection device according to the claim, wherein the analog signal processor comprises a low pass filter circuit and a band pass filter circuit, wherein the low pass filter circuit retains the infrared signal and the DC signal of the red signal. And filtering out the alternating current signals of the infrared light signal and the red light signal, the band pass wave circuit retaining the infrared light signals and the alternating current signals of the red light signals to filter out the infrared light signals and the red light These DC signals of the signal. The physiological detecting device according to claim 5, wherein the low-pass filter circuit has a cutoff frequency ranging from 0.1 Hz to 1 〇 Hz, and the band pass filter circuit has a cutoff frequency ranging from 1 Hz to 2 Hz. . The physiological detecting device according to claim 1, wherein the alternating current signals comprise a plurality of early pulse waves, wherein the unit pulse wave comprises a first peak, a second peak and two valleys, and the valley is perpendicular to the first peak The distance is a first amplitude of the unit pulse wave, and the ratio of the first amplitude to the corresponding DC signal is a perfusion index in the physiological parameter. The physiological detecting device according to claim 7, wherein a vertical distance from the trough to the second peak is a second amplitude of the unit pulse wave, and a ratio of the second amplitude to the first amplitude is a pulse in the physiological parameter Reflective indicator. According to the physiological detection device of the request item, a display capable of displaying a parameter of 1 liter is further included. 10. A physiological detection system comprising: a physiological detection device comprising: -21 · 201228633 a light emitter that alternately emits an infrared beam and a red light beam to a living body; a light sensor received from the organism The infrared light beam and the red light light respectively reflect and transmit an infrared light signal and a red light signal; and the analog signal processor processes the infrared light signal and the red light signal and separates the infrared light signal An alternating current signal and an alternating current signal of the infrared light signal, separating a direct current signal of the red light signal and one of the red light signals; and a microcontroller controlling the light emitting device to emit the infrared light beam and the red light The light beam is used by the microcontroller to calculate a physiological parameter from the DC signal of the infrared light signal and the alternating current signal and the red light signal and the alternating current signal; a computer 'storing the infrared light signal and the red The DC signals of the optical signals and the alternating current signals, analyzing the physiological parameters, and instantly displaying the physiological parameters ; And a data fetch unit operations' transmits the infrared light signal and the red signal of the plurality of the plurality of AC signal and DC signal to the computer. 11. According to the physiological detection system of claim 1, further comprising an analogy multiplex! § 'The analog multiplexer electrically couples the optical sensor and can separate the infrared light signal and the red light signal' for input Analog signal processor. 12. The physiological detection system according to claim 1, wherein the light emitter comprises a red LED, an infrared diode, and a driving circuit electrically coupled to the microcontroller. Controlling the driving circuit to interactively drive the -22-201228633 red light diode with the infrared light diode. 13. The physiological detection system of claim 10, wherein the light sensor comprises a light receiving diode and a current converting voltage circuit, the light receiving diode receiving the infrared light beam reflected or transmitted from the living body and The red light beam generates at least one current, and the current-to-voltage circuit generates the infrared light signal and the red light signal according to the current conversion. I4. The physiological detection system according to claim 10, wherein the analog signal processor comprises a low pass filter circuit and a band pass filter circuit, wherein the low pass filter circuit retains the infrared signal and the DC signal of the red signal And filtering out the alternating current signals of the infrared light signal and the red light signal, the band pass wave circuit retaining the infrared light signals and the alternating current signals of the red light signals to filter out the infrared light signals and the These DC signals of red light signals. 15. The physiological detection system according to claim 14, wherein the low pass filter circuit has a cutoff frequency ranging from 0.1 Hz to 1.0 Hz, and the band pass filter circuit has a cutoff frequency ranging from 1 Hz to 20 Hz. . 16. The physiological detection system according to claim 10, wherein the alternating current signals comprise a plurality of unit pulse waves 'the unit pulse wave comprises a first peak, a first peak and two valleys, and the valley is perpendicular to the first peak The distance is one of the unit pulse waves, and the ratio of the amplitude to the corresponding DC signal is a perfusion index in the physiological parameter. 17. The physiological detection system of claim 16, wherein a vertical distance from the trough to the second peak is a second amplitude of the unit pulse wave, and a ratio of the second amplitude to the first amplitude is in the physiological parameter A pulse reflex indicator. -23. 201228633 1 8. The physiological detection system according to claim 6, wherein the ratio of the height of the living body to the delay time of the first amplitude to the second amplitude is an index of hardening of the blood vessel in the physiological parameter. 19. The physiological detection system according to claim 10, wherein one of the average values of the alternating current signals after Fourier transform is a pulse diagnosis indicator. •twenty four·