TW201138623A - Method to reduce the frequency and/or intensity of blossom-end rot disorder in horticultural crops - Google Patents

Method to reduce the frequency and/or intensity of blossom-end rot disorder in horticultural crops Download PDF

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TW201138623A
TW201138623A TW100103217A TW100103217A TW201138623A TW 201138623 A TW201138623 A TW 201138623A TW 100103217 A TW100103217 A TW 100103217A TW 100103217 A TW100103217 A TW 100103217A TW 201138623 A TW201138623 A TW 201138623A
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fruit
trifluoro
sensitive
rot
frequency
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TW100103217A
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Chinese (zh)
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Andreas Goertz
Dirk Ebbinghaus
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Bayer Cropscience Ag
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
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Abstract

Use of Trifloxystrobin to reduce the frequency and/or intensity of blossom-end rot disorder in a horticultural crop.

Description

201138623 六、發明說明： 【發明所屬之技術領域】 本發明係有關一種以三|L敏（Trifloxystrobin)於降 低園藝作物果頂腐爛病之頻率及/或強度上之用途。 【先前技術】 果頂腐爛病係某些園藝作物如：蕃茄、胡椒及茄子 之嚴重病害。該病害會造成各果實之果頂腐爛，降低受 害果實之市場賣相。 果頂腐爛病之症狀、發生率及肇因已有很多說明。 例如.俄亥俄州州立大學推廣教育（〇hi〇 state University Extension)發表之 ” Extension Fact Sheet (HYG-3117-96 ’ 作者 Sally A. Miller，Randall，C. Row 及 Richard Riedel ， 可參 見網站 http://ohioline.osu.edu/hyg-fact/3000/ 3117.html)，標題為 "蕃祐、胡椒及祐子之果頂腐爛病（Blossom-End Rot of Tomato, Pepper and Eggplant)”，其說明此病害之症狀、 原因及處理法。 其中針對蕃茄及茄子之說明，果頂腐爛病通常始於 果頂出現小區域水疱，其可能在果實轉綠或成熟時出 現。隨著病害發展，其會擴大，轉呈凹陷變黑及硬化。 嚴重時，可能完全覆蓋果實下半部，轉呈平坦或凹陷。 其中亦說明可能有繼發病原菌侵襲損傷處，經常造成受 害害果實完全損毀。 201138623 其中進一步強調，果頂腐爛病為一種與果實妈濃度 低有關之生理性病害。正常細胞生長需要相當高鈣濃 度。當快速生長之果實耗盡所必要之鈣時，組織即會瓦 解’在果頂出現凹陷損傷。當鈣之需要超過供應量時， 即誘發果頂腐爛病。此點可能因土壤中鈣含量低或競爭 性陽離子含量高、乾旱壓力或土壤水份波動過大導致進 入植物之鈣吸收量及移動量減少、或因過多氮肥導致快 速之營養性生長所致。 此外’多數研究證實’遠端果實組織之局部鈣缺乏 為主要原因。在園藝操作中，已知可藉由降低樹頂蒸 散’促進鈣移向果實(Li，Y.L.，Stanhhellini，C, & Challa， Η· 2001:導電性與蒸散作用對溫室蕃蘇（LyCOpersicum esculentum L.)生產之影響（Effect of electrical conductivity and transpiration on production of greenhouse tomato(Lycopersicum esculentum L.).201138623 VI. INSTRUCTIONS OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates to the use of Trifloxystrobin for reducing the frequency and/or intensity of horticultural crop rot. [Prior Art] Fruit rot is a serious disease of certain horticultural crops such as tomatoes, peppers and eggplants. The disease causes the top of each fruit to rot and reduce the market selling of the damaged fruit. There have been many explanations for the symptoms, incidence and causes of rot of fruit. For example, Ohio State University Promotion Education (〇hi〇state University Extension) published "Extension Fact Sheet (HYG-3117-96' by Sally A. Miller, Randall, C. Row and Richard Riedel, see website http:/ /ohioline.osu.edu/hyg-fact/3000/ 3117.html), titled "Blossom-End Rot of Tomato, Pepper and Eggplant", which explains The symptoms, causes and treatment of the disease. In the case of tomatoes and eggplants, fruit rot usually begins with a small area of blisters on the top of the fruit, which may appear when the fruit turns green or mature. As the disease progresses, it will expand and turn into depressions to darken and harden. In severe cases, it may completely cover the lower part of the fruit and turn flat or concave. It also indicates that there may be damage to the affected pathogen, which often causes the damaged fruit to be completely destroyed. 201138623 It is further emphasized that fruit rot is a physiological disease associated with low concentration of fruit mom. Normal cell growth requires a fairly high calcium concentration. When the fast-growing fruit depletes the calcium necessary, the tissue collapses and sag damage occurs at the top of the fruit. When the need for calcium exceeds the supply, the fruit rot is induced. This may be due to low calcium in the soil or high levels of competitive cations, drought stress or excessive fluctuations in soil moisture resulting in reduced calcium uptake and movement into the plant, or rapid nutrient growth due to excessive nitrogen fertilizer. In addition, most studies have confirmed that local calcium deficiency in distal fruit tissues is the main cause. In horticultural operations, it is known to promote calcium migration to fruits by reducing tree top evapotranspiration (Li, YL, Stanhhellini, C, & Challa, Η 2001: Conductivity and evapotranspiration against greenhouse gases (LyCOpersicum esculentum L) .)Effect of electrical conductivity and transpiration on production of greenhouse tomato (Lycopersicum esculentum L.).

ScientiaHorticulturae，88, 11-29)或直接施加鈣(Wada，T” Ikeda，H.，Ikeda，M. & Furakawa，H. (1996):葉部施加妈 溶液對蕃茄果頂腐爛病發生率之影響(Effects of foliar application of calcium solutions on the incidence of blossom-end rot of tomato fruit)Journal of Japanese Society for Horticultural Science, 65, 553-558; Ho, L.C. (1998):控制鈣吸收、轉運及利用之環境與生理因素對玻 璃室中蕃莊與甜椒產量與品質之定量法（To quantify environmental and physiological factors controlling 201138623 calcium uptake, transport and utilization on yield and quality of tomato and sweet peppers in glasshouses). Final report on MAFF project HH1309SPC; Schmitz-Eiberger, M.，Haefs，R. & Noga，G. (2002):鈣缺乏症-對蕃茄植物 之抗氧化防禦系統之影響（Calcium deficiency- influence on the antioxidative defense system in tomato plants).Journal of Plant Physiology，159, 733-742)，以使 果頂腐爛病降至最低程度。ScientiaHorticulturae, 88, 11-29) or direct application of calcium (Wada, T" Ikeda, H., Ikeda, M. & Furakawa, H. (1996): The incidence of tomato fruit rot in the application of fum solution Effects of foliar application of calcium solutions on the incidence of blossom-end rot of tomato fruit Journal of Japanese Society for Horticultural Science, 65, 553-558; Ho, LC (1998): Controlling calcium absorption, transport and utilization To quantify environmental and physiological factors controlling 201138623 calcium uptake, transport and utilization on yield and quality of tomato and sweet peppers in glasshouses. Final report on MAFF project HH1309SPC; Schmitz-Eiberger, M., Haefs, R. & Noga, G. (2002): Calcium deficiency - influence on the antioxidant defense system in tomato plants (Calcium deficiency- influence on the antioxidative defense system in Tomato plants).Journal of Plant Physiology, 159, 733-742) to minimize fruit rot disease .

Sally A. Miller、Randall，C. Row 及 Richard Riedel 在上述Extension Fact Sheet中建議例如：施加石灰維持 土壤pH約6.5 ’將可供應約並提高土壤中弼離子對其 他競爭離子之比例，或使用硝酸態氮作為氮肥來源，因 為過量銨離子會降低鈣吸收，因此氨態氮可能加重果頂 腐爛病’或可利用覆蓋物及/或灌溉法避免乾旱壓力及 土壤水份波動。 然而，Ho & White (Ho, L.C. & White，P.J. (2005): 誘發蕃茄果實果頂腐爛病之細胞學假說（A cellular hypothesis for the induction of blossom-end rot in tomato fruit stated). Annals of Botany, 95, 571-581)指出現代玻 璃室/溫室果實生產（尤其在蕃茄生產）中，很少因鈣供 應不當而誘發果頂腐爛病。反之，果頂腐爛病更常出現 在鈣肥適當時，尤其當在鈣減少轉運至快速生長的遠端 果實組織或遠端果實組織因加速發展果實而鈣需要量 增加之條件下栽培時(Ho, L.C. (1998)··利用栽培法改良 5 201138623 蕃茄果實品質（Improving tomato fruit quality by cultivation)。說明於：Cockshull, K.E.，Gray，D.，Seymour, G.B.，Thomas, B.編輯之”園藝作物之遺傳與環境操作Sally A. Miller, Randall, C. Row, and Richard Riedel suggested in the above Extension Fact Sheet that, for example, applying lime to maintain a soil pH of about 6.5' would supply and increase the ratio of strontium ions to other competing ions in the soil, or use nitric acid. Nitrogen is used as a source of nitrogen fertilizer because excessive ammonium ions reduce calcium absorption, so ammonia nitrogen may aggravate fruit rot disease or use cover and/or irrigation methods to avoid drought stress and soil moisture fluctuations. However, Ho & White (Ho, LC & White, PJ (2005): A cellular hypothesis for the induction of blossom-end rot in tomato fruit stated. Annals of Botany, 95, 571-581) pointed out that in modern glass chamber/greenhouse fruit production (especially in tomato production), fruit rot is rarely induced by improper calcium supply. Conversely, fruit rot is more common when calcium fertilizer is appropriate, especially when calcium is transported to rapidly growing distal fruit tissue or distal fruit tissue is grown under conditions that accelerate the development of fruit and increase calcium requirements (Ho , LC (1998)··Improved tomato fruit quality by cultivation by using cultivation method. Description: Cockshull, KE, Gray, D., Seymour, GB, Thomas, B. Edited “horticultural crops” Genetic and environmental operations

cropW. Wallingford，UK: CAB International, 17-29)。 【發明内容】 本發明者現在發現，當施加三氟敏時，可大幅降低 出現在園藝作物中之果頂腐爛病強度。 此點令人驚言牙，因為嗜越果傘素(strobilurine)型態 殺真菌劑：（五)-曱氧基亞胺基-{(五)-α-[1-(α，α，α-三氟-間 曱苯基）亞乙基胺基氧]-鄰曱苯基}乙酸曱酯，通常稱為 三氟敏，且化學式如下cropW. Wallingford, UK: CAB International, 17-29). SUMMARY OF THE INVENTION The present inventors have now found that when trifluoro-sensitive is applied, the strength of fruit rot that occurs in horticultural crops can be greatly reduced. This is a shocking tooth because of the strobilurine type fungicide: (5)-nonyloxyimido-{(f)-α-[1-(α,α,α -Trifluoro-m-phenylphenyl)ethylidene oxy]-o-phenylene acetate oxime ester, commonly known as trifluoro-sensitive, and the chemical formula is as follows

已知其可有效控制廣範圍之真菌性病原菌（參見 ΕΡ-Β-460575 及 US-A-2005-0032903)。雖然已知三氟敏 對植物健康及品質有正面效應（如：穀内蛋白質含量-參見Clark，D.C. (2003)”三氟敏對生長中小麥之型態 與生化影響之農藝效應(Agronomic implications of some 6 201138623 morphological and biochemical effects of Trifloxystrobin in wheat growing)” .Pflanzenschutz-Nachrichten Bayer 56 (2)，281-296;改善非生物性應激壓力耐受性-參見 Freundorfer，I (2008)”應激壓力越低-產量越高（Less stress - higher yield)”，Bayer CropScience Courier 2, 1 M3) ’但目前均未了解三氟敏可能亦可有效降低果頂 腐爛病之頻率及/或強度。 囚此，本發明係有 卞IA taj云I 月匕 出現果頂腐爛病之頻率及/或強度上之用途，且亦有關 使用二氟敏降低果頂腐爛病頻率及/或強度之方法。 本發明一項態樣中，三氟敏特別適用於降低果實 (如：蕃茄、胡椒及茄子）之果頂腐爛病頻率及/或強产。 根據本發明之園藝作物包括下列作物：胡蘿8广南 瓜(pumpkin、squash)、櫛瓜、馬鈐薯、甜玉米、：、，窜、 觀賞植物、藥草、食用草本植物、蕃茄 ，心 苣' 小黃瓜1菜'甜菜、捲心菜、花菜、球 =藍一、球莖甘藍、羽衣甘藍分、蘿《、大頭菜、 盧旬、且類、腕豆、蘋果、覆盆子、草每、香蕉、 c:桃:/、#石榴、鳳t石槽、大蒜、辣椒(:二 咖）、蘿蔔、揚桃、木#、胡桃、檸檬、橘子 (mangold)、香菇、撖欖、柳橙、木瓜、 ^ . 邱'椒、百香果、 ^、核桃、梅子、開心果、柿、柚子（葡萄抽）、祐子、 翱巨、蔓越莓、醋栗、榛果、奇異果、杏仁、 桃、朝鮮薊、駱梨、黑莓、腰果、樓桃、二辟菜、杏 货祧、柑橘、椰子、 201138623 洋香瓜，且包括其採收之產品（如：果實及在本文中通 常稱為果實之蔬菜）。 根據本發明’三氟敏係自開花期（亦即完全開花及 有功能期間。開花期亦指花期開始時）之前開始，在不 同生長階段施加。 較佳係在溫室生產園藝作物時使用三氟敏。 本發明一項態樣中’三氟敏係呈商品調配物使用， 由此等調配物與其他活性化合物（如：殺昆蟲劑、引誘 劑、消毒劑、殺菌劑、殺碑蜗劑、殺線蟲劑、殺真菌劑、 調節生長物質、除草劑、保護劑(safener)、肥料或化學 4吕息物質及生物防治劑（如.酵母菌（Mebc/m/AovWa 形成混合物，製成使用型式。 特別有利之混合化合物為例如：殺真菌劑，如： 核酸合成抑制劑，例如：本達樂(benalaxyl)、本達樂-M、 布滅莫（bupirimate)、克拉肯（clozylacon)、地滅利 (dimethirimol)、抑利莫(ethirimol)、伏拉希(furalaxyl)、 殺紋寧（hymexazole)、滅達樂(metalaxyl)、滅達樂-Μ、 歐弗斯（ofurace)、歐殺斯（oxadixyl)及啐琳酸（ox〇iin acid)。有絲分裂與細胞分化之抑制劑，例如：免賴德 (benomyl)、卡苯辛（carbendazim)、氯吩。坐 (chlorfenazole)、地吩卡（diethofencarb)、°塞嗤菌胺 (ethaboxam)、伏塔唾（fuberidazole)、賓克隆 (pencycuron)、腐絕（thiabendazole)、多保淨 (thiophanate)、曱基多保淨(thiophanate-methyl)及索醯胺 8 201138623 (zoxamide)。呼吸抑制劑，例如：作為CI-呼吸抑制劑之 地伏靈（diflumetorim);作為CII-呼吸抑制劑之必賽吩 (bixafen)、保卡利(boscalid)、卡布辛(carboxin)、芬伏爛 (fenfuram)、護坦尼（flutolanil)、護派楠（flUOpyram)、福 滅普（furametpyr)、福滅克（furmecyclox)、抑本散 (isopyrazam)(順式-差向異構性消旋物irs，4SR，9RS與 反式-差向異構性消旋物1RS，4SR，9SR之混合物）、抑本 散(順式-差向異構性消旋物1RS，4SR，9RS)、抑本散(順 式-差向異構性消旋物1R,4S，9R)、抑本散(順式-差向異 構性消旋物1 S，4R,9S)、抑本散(反式-差向異構性消旋物 1RS，4SR，9SR)、抑本散（反式-差向異構性消旋物 1R，4S，9S)、抑本散(反式-差向異構性消旋物is，4R，9R)、 米普尼（mepronil)、嘉得信（0XyCarb0Xin)、本福吩 (penflufen)、本赛能(penthiopyrad)、速達散(sedaxane)、 地伏醯胺(thifluzamide);作為CIII-呼吸抑制劑之安美速 (amisulbrom)、亞托敏（azoxystrobin)、赛發滅 (cyazofamid)、醚菌胺（dimoxystrobin)、烯两菌西旨 (enestrobin)、芬色丹（famoxad〇ne)、芬滅酉同 (fenamidone)、氟嘧菌酯（fiuoxastr〇bin)、醚菌醋 (kresoxim-methyl)、苯氧菌胺(metominostrobin)、月亏 _ 菌 胺（orysastrobin)、啶氧菌酯（picoxystr〇bin)、唑菌胺醋 (pyraclostrobin)、口坐菌醋（pyraoXyStr〇bin)、唾胺菌酉旨 (pyrametostrobin)、吼菌笨威（pyribencarb)、三氟敏 (trifloxystrobin)。可作為去偶合劑之化合物，例如：百 201138623 瞒克（binapacryl)、白粉克（dinocap)、富米松(ferimzone)、 扶吉胺（fluazinam)與敵瞒普（meptyldinocap)。ATP 生產 抑制劑，例如：三苯醋錫（fentin acetate)、三苯氯錫（fentin chloride)、三苯錫氫氧化物（fentin hydroxide)，及胺基酸 生合成與/或蛋白質生合成抑制劑，例如：安得靈 (andoprim)、保米黴素-S(blasticidin Silthiofam -S)、西迪 尼（cyprodinil)、賜黴素(kasugamycin)、賜黴素鹽酸鹽水 合物、米本靈（mepanipyrim)及比坦尼(pyrimethanil)。訊 號轉導抑制劑，例如：芬比克尼（fenpiclonil)、伏克尼 (fludioxonil)及克辛芬(quinoxyfen)。脂質與膜合成抑制 劑’例如：聯苯、氣哇内（chlozolinate)、護粒松 (edifenphos)、依得利（etridiazole)、蛾卡（iodocarb)、喜 樂松（iprobenfos)、依普同（iprodione)、亞賜普醇烧 (isoprothiolane)、撲滅寧（procymidone)、普莫卡 (propamocarb)、普莫卡鹽酸鹽、白粉松(pyrazophos)、 曱基脫克松(tolclofos-methyl)及免克寧(vinclozolin)。麥 角固醇生合成抑制劑，例如：艾狄莫(aldimorph)、阿克 嗤（azaconazole)、拜坦諾（bitertanol)、布康唑 (bromuconazole)、西普康。坐（cyproconazole)、二氣丁唾 (diclobutrazole)、地吩康 〇坐（difenoconazole)、地康唾 (diniconazole)、地康唑-M、得莫（dodemorph)、得莫乙 酸鹽、環氧克β坐(epoxiconazole)、抑達唆(etaconzole)、 芬利莫（fenarimol)、芬康唾（fenbuconazole)、吩醯胺 (fenhexamide)、芬普定（fenpropidin)、芬普福 201138623 (fenpropimorph)、伏克康唾（fluquinconazole)、伏米得 (flurprimidol)、護石夕得（flusilazole)、護汰芬（flutriafol)、 伏康唾（furconazole)、順式伏康嗤、赫康口坐 (hexaconazole)、依滅列(imazalil)、依滅列硫酸鹽、抑本 康0坐（imibenconazole)、抑普康吐（ipconazole)、滅康口坐 (metconazole)、麥克坦尼（myclobutanil)、納得吩 (naftifin)、紐:莫（nuarimol)、口咢康口坐（oxpoconazole)、巴 克素（paclobutrazole)、比菲口坐（pefurazoate)、本康嗤 (penconazole)、旅布靈（piperalin)、撲克樂（prochloraz)、 普克利（propiconazole)、普賽康〇坐(prothioconazole)、必 達克（Pyributicarb)、比芬斯（pyrifenox)、克康唾 (quinconazole)、辛康0坐(simeconazole)、賜必安 (spiroxamine)、得克利（tebuconazole)、特本吩 (terbinafin)、特康唾（tetraconazole)、三泰芬 (triadimefon)、三泰隆（triadimenol)、赛得莫 (tridemorph)、三伏唑(triflumizole)、賽福寧（triforine)、 三狄康唑(triticonazole)、優康唑（uniconazole)、芬克唑 (viniconazole)與福康唑(voriconazole)。細胞壁合成抑制 劑’例如：苯賽卡（benthiavalicarb)、地滅莫 (dimethomorph)、伏莫（flumorph)、抑發利（iprovalicarb)、 曼普胺(mandipropamid)、保粒黴素(p〇ly〇xins)、保粒靈 (polyoxorim)、（prothiocarb)、瓦利黴素 A(validamycinA) 與發利列(valifenalate)。黑色素生合成抑制劑，例如： 卡普醯胺（capropamide)、地克賽（diclocymet)、芬散尼 201138623 (fenoxanil)、太得(phthalide)、百快隆(pyr〇qUii〇n)與三賽 唑(tricyclazole)。可以誘發宿主防禦性之化合物，例如： 艾苯拉(acibenzolar)-S-曱基、異噻菌胺(is〇tianil)、撲殺 熱(probenazole)與地得尼（tiadinil)。具有多重位置作用 之化合物’例如：波爾多（Bordeaux)混合物、四氯丹 (captafol)、蓋普丹（captan)、四氣異苯腈 (chlorothalonil)、萘曱酸銅、氧化銅、氯氧化銅、銅製 劑如：氫氧化銅、硫酸銅、益發靈（dichlofluanid)、腈硫 醌（dithianon)、多寧（dodine)、多寧游離鹼、富爾邦 (ferbam)、護福爾培(fluorofolpet)、福爾培(folpet)、免熱 淨(guazatine)、免熱淨乙酸鹽、抑克定（iminoctadine)、 抑克定苯烧績酸鹽（iminoctadine albesilate)、抑克定 (iminoctadine)三乙酸鹽、|孟銅（mancopper)、I孟粉克 (mancozeb)、猛乃浦（maneb)、滅得賴（metiram)、滅得賴 鋅鹽、快得寧（oxine-copper)、丙氧苯脉(propamidine)、 曱基鋅乃浦(propineb)、硫與硫製劑（包括：多硫化鈣）、 得恩地(thiram)、特伏奈(tolylfuanid)、鋅乃浦(zineb)與 益穗(ziram)。 其他化合物，例如：2,3-二丁基-6_氣噻吩并[2,3-d] 嘧啶-4(3H)-酮、（2Z)-3-胺基-2-氰基-3-苯基丙-2-烯酸乙 酯、N-[2-(l，3-二曱基丁基）苯基]氟-1，3-二曱基-1H-吡唑-4-羧醯胺、3-(二氟曱基)-1-曱基-N-(3'，4，，5，-三氟聯 苯-2-基）-1Η-吼唑-4-羧醯胺、3-(二氟曱基）-N-[4-氟 -2-(l,l，2,3,3,3-六氟丙氧基）苯基]-1-曱基-1H-吡唑-4-羧 12 201138623 酿胺、（2E)-2-(2-{[6-(3-氣-2-甲基苯氧基)_5_氟嘧啶_心 基]氧}苯基）-2-(甲氧基亞胺基）_N_甲基乙醯胺、 (2E)_2-{2_[({[(2e，3e)-4_(2,6^ 氣苯基）丁_3_烯_2_亞基] 胺基}氧）甲基]苯基}-2-(甲氧基亞胺基卜沐甲基乙醯 胺、2-氯-N-(l，l，3-三甲基·2,3-二氫-1H-茚-4·基）吡啶_3_ 羧醯胺、Ν-(3-乙基-3,5,5-三曱基環己基)_3_(甲醯基胺 基）-2-羥基苯甲醯胺、5_甲氧基_2_甲基 -4·(2-{[({(1Ε)-1-[3-(三氟甲基）苯基]亞乙基}胺基）氧]甲 基}苯基)-2,4-二氫-3Η-1,2,4-三唑-3-酮、（2Ε)-2_(甲氧基 亞胺基)-Ν-甲基-2-(2-{[({(1职_[3_(三氟甲基）苯基]亞 乙基}胺基）氧]曱基}苯基）乙醯胺、（2Ε)_2_(曱氧基亞胺 基)-Ν-甲基-2-{2邮)-({1_[3_(三氟甲基)苯基]乙氧基}亞 胺基）曱基]苯基丨乙醯胺、 (2E)-2_{2-[({[(ie)-1-(3_{[(e)-1-氟 _2_ 苯基乙烤基]氧）苯 基)亞乙基]月女基}氧）甲基]苯基}·2_(曱氧基亞胺基)曱 基乙醯胺、1-(4-氣苯基）_2-(ih-1，2,4-三唑-1-基）環庚 醇、1-(2,2_二曱基·2,3-二氫-1H-節-1-基)_1H_味唑 _5_ 敌 酸曱酯、N-乙基-N-曱基_N，-{2-曱基-5-(三氟甲 基）-4-[3-(三曱基矽烷基）丙氧基]苯基}亞醯胺基甲醯 胺、N’-{5-(二氟曱基)-2曱基_4-[3-(三曱基石夕燒基)丙氧 基]苯基}-N-乙基-N-曱基亞醯胺基曱醯胺、1H_咪唑-^ 羧硫代酸〇-{1-[(4-甲氧基苯氧基）曱基]_2,2_二甲基丙 基}酉旨、N-[2-(4_{[3_(4-氣笨基)丙_2·炔+基]氧}_3-甲氧 基苯基）乙基]-Ν2-(曱基磺醯基)纈胺醯胺、5_氣_7_(4-曱 13 201138623 基旅咬小基)_6_(2,4,6_三氣笨基犯圳三唾并嘧 唆、5-胺基-1，3,4-嗟二峻-2-硫醇、霜黴威乙膦酸鹽 (propamocarb-fosetyl)、1H-咪唑羧酸 1[(4_曱氧基笨 氧基）曱基]-2,2-二曱基丙酷、^曱基例吼⑵—四氟 乙氧基）本基]-3-(二氟曱基比ϋ坐_4_竣酿胺、2 3 5 6-四氯-4-(曱基磺醯基）吡啶、2-丁氧基_6_碘_3_丙基-4Η_ 色烯-4-酮、2-苯基苯酚及鹽類、3_(二氟甲基卜卜甲基 -N-[2-(l，l，2,2-四氟乙氧基）苯基]_ιη_π比唾_4_叛醯胺、 3,4,5-二氯0比咬-2,6-一甲腈、3-[5-(4-氣苯基)_2,3-二甲基 異畤唑啶-3-基]吼啶、3-氣-5-(4-氣苯基)_4_(2,6_二氟苯 基)-6-甲基。合畊、4-(4-氯苯基)-5-(2,6-二氟苯基)_3,6_二 曱基嗒畊、喹啉-8-酚、喹啉-8-酚硫酸鹽（2:1)、美爾奎 寧（tebufloquin)、5-甲基-6-辛基-3,7-二氫[1，2,4]三唆并 [l，5-a]e密咬-7-胺、5-乙基-6-辛基-3,7-二氫[1，2,4]三唆并 [l，5-a]。密咬-7-胺、辛嗤。密菌胺（arnetoctradin)、苯嗟。坐 (benthiazole)、苯呤畊（bethoxazin)、卡普黴素 (capsimycin)、卡吩（carvone)、喧琳曱硫胺酸鹽 (chinomethionate)、地茂散(chloroneb)、庫發尼（cufraneb)、 賽伏醢胺(cyfhifenamid)、西莫尼（Cymoxanil)、賽磺醯胺 (cyprosulfamide)、得滅（dazomet)、迪布卡（debacarb)、 二氯吩(dichlorophen)、地克美辛（diclomezine)、大克爛 (dicloran)、地吩唾克(difenzoquat)、地吩σ坐克曱基疏酸 鹽、二苯基胺、抑克滅(ecomat)、富米松(ferimzone)、 伏特夫（flumetover)、氟吡菌胺（fluopicolid)、氟菌丹 201138623 (fluoroimid)、護硫醯胺（flusulfamide)、噻菌淨（flutianil)、 福赛得(fosety 1-aluminium)、乙膦妈（fosety 1-calcium)、乙 膦納（fosetyl-sodium)、六氯笨、依麻黴素(irumamycin)、 異 0塞菌胺（isotianil)、滅速卡（methasulphocarb)、 (2E)-2-{2-[({環丙基[(4-曱氧基苯基)亞胺基]曱基}硫）曱 基]苯基} -3 -曱氧基丙稀酸曱g旨、異疏氰酸曱g旨、滅奇吩 (metrafenone)、（5-氯-2-曱氧基-4-曱基吡啶-3-基)(2,3,4-三曱氧基-6-曱基苯基）曱酮、米德黴素(mildiomycin)、 特伏尼(tolnifanide)、N-(4-氣苯曱基)-3-[3-曱氧基-4-(丙 -2-炔-1-基氧）苯基]丙醯胺、N-[(4-氯苯基）（氰基）曱 基]-3-[3-甲氧基-4-(丙-2-炔-1-基氧）苯基]丙醯胺、N-[(5-溴-3-氯吡啶-2-基）曱基]-2,4-二氯吡啶-3-羧醯胺、 N-[l-(5-溴-3-氣吡啶-2-基）乙基]-2,4-二氯吡啶-3-羧醯胺、 N-[ 1-(5->臭-3 -氯0比π定-2-基）乙基]-2-氣-4-蛾0比咬-3-緩酿 胺、Ν-{(Ζ)-[(環丙基曱氧基）亞胺基][6-(二氟甲氧 基)-2,3-二氟苯基]甲基}-2-苯基乙醯胺、Ν-{(Ε)-[(環丙基 曱氧基)亞胺基][6-(二氟曱氧基)-2,3-二氟苯基]曱基}-2-苯基乙醯胺、納坦黴素(natamycin)、二曱基二硫代胺甲 酸鎳、确基太(nitrothal)-異丙基、歐奇農（octhilinone)、 歐賽保（oxamocarb)、歐芬汀(oxyfenthiin)、五氯紛與其 鹽類、吩σ井-1-叛酸、盼丁滅兹(phenothrin)、構酸與其 鹽類、霜黴威乙膦酸鹽(propamocarb-fosetylate)、普辛 納（propanosine-sodium)、普克奇(proquinazid)、〇比口各靈 (pyrrolnitrine)、克地辛（quintozene)、5-胺基-2-(1-曱基 15 201138623 乙基)-4-(2-曱基苯基)-3-側氧基-2,3-二氫唾小硫 代曱酸S-丙-2-稀-1-基S旨、特克爛(tecloftalam)、特康辛 (tecanazene)、三唑氧(triazoxide)、三氣醯胺（trichlamide)、 5-氣-Ν'-苯基-Ν'-丙-2-快-1-基β塞吩-2-亞硫羧基酿肼、奇 利醯胺（2&1*^111丨(^)、]^-甲基-2-(1-{[5-曱基-3-(三氣甲 基）比唑-1-基]乙醯基}哌啶-4-基）-N-[(1R)-1,2,3,4-四氫萘-1-基]-1,3-噻唑-4-羧醯胺、N-曱基-2-(l-{[5-曱基 -3-(三氟曱基）-1Η- °比唆-1-基]乙醯基}派。定冰 基)-N-(l，2,3,4-四氫萘-1-基)-1，3-嗟唾-4-羧醢胺、3-(二氟 曱基)-Ν-[4-氟-2-(1，1，2,3,3,3-六氟丙氧基）苯基]_1_曱基 -1Η-0比嗤-4-繞醯胺及{6-[({[(1-曱基-1Η-四嗤-5-基）（苯 基）亞曱基]胺基}氧）曱基]吡啶-2-基}胺曱酸戊酯。 此外，殺昆蟲劑、殺蜱蟎劑及殺線蟲劑’如：乙醯 基膽鹼酯酶(AChE)抑制劑’例如：胺曱酸酯類，例如： 安利卡（alanycarb)、得滅克（aidicarb)、本得卡 (bendiocarb)、本伏卡（benfuracarb)、布卡辛 (1)11〖〇〇&1^(^111)、丁氧布卡辛（131^0巧(^1)(；^111)、加保利 (carbaryl)、力σ 保扶（carb〇furan)、丁基力σ 保扶 (carbosulfan)、抑芬卡（ethiofencarb)、芬布卡 (fenobucarb)、覆滅蟎（formetanate)、伏賽卡 (furathiocarb)、滅必為（isoprocarb)、滅賜克（methiocarb)、 納乃得(methomyl)、滅特卡(met〇icarb)、歐殺滅(〇xamyl)、 比加普（pirimicarb)、安丹(pr〇p0xur)、硫敵克（thiodicarb)、 硫务斯（thiofanox)、三辛滅（trjazamates)、三滅卡 201138623 (trimethacarb)、XMC 與賽利卡(xylylcarb);或有機磷酸 酯類，例如：歐殺松(acephate)、亞滅伏(azamethiphos)、 谷速松(azinphos)(-曱基、-乙基）、卡速松(cadusafos)、 氯乙松(chlorethoxyfos)、氯芬松(chlorfenvinphos)、氯滅 松(chlormephos)、陶斯松(chlorpyrifos)(-曱基）、庫伏斯 (coumaphos)、氰乃松(cyanophos)、滅賜松(demeton)-S-曱基、大利松((^2^1011)、二氯松((^11101^05)/〇〇\^、雙 特松（dicrotophos)、大滅松（dimethoate)、大芬松 (dimethylvinphos)、二硫松（disulfoton)、EPN、愛殺松 (ethion)、普伏松(ethoprophos)、凡伏(famphur)、芬滅松 (fenamiphos)、撲滅松(fenitrothion)、芬殺松(fenthion)、 福賽特（fosthiazate)、飛達松（heptenophos)、抑伏松 (isofenphos)、0-(曱氧基胺基硫代構醯基)水楊酸異丙基 酯、抑殺松（isoxathion)、馬拉松（malathion)、滅加松 (mecarbam)、達馬松（methamidophos)、滅大松 (methidathion)、美文松（mevinphos)、亞素靈 (monocrotophos)、乃立松(naled)、歐滅松(omethoate)、 歐滅賜松(oxydemeton)-曱基、巴拉松(parathion)(-甲基）、 賽達松（phenthoate)、福瑞松（phorate)、裕必松 (phosalone)、益滅松（phosmet)、福賜米松 (phosphamidon)、辛硫磷(phoxim)、亞特松(pirimiphos)(-曱基）、佈飛松(profenofos)、普丹松(propetamphos)、普 硫松（prothiofos)、必伏松（pyraclofos)、必芬松 (pyridaphenthion)、拜裕松（quinalphos)、速伏特 17 201138623 (sulfotep)、特必松(tebupirimfos)、亞培松(temephos)、 託福松（terbufos)、四氯松（tetrachlorvinphos)、硫滅松 (thiometon)、三落松（triazophos)、三氯松（triclorfon)與 繁米松(vamidothion)。GAB A-閘控之氣離子通道擷抗 劑’例如.有機氯，例如：克丹（chl〇rdane)、安殺番 (endosulfan)(a·);或飛普洛類(Fiprols)(苯基吡唑類），例 如.抑普洛（ethiprole)、芬普洛（fipronil)、帕普洛 (pyrafluprole)與普洛(Pyripr〇le)。鈉通道調節劑/依賴電 壓之鈉通道阻斷劑’例如：擬除蟲菊酯類，例如：阿納 寧（acrinathrin)、亞特靈（allethrin)(d-順式-反式，d-反式）、 畢芬寧（bifenthrin)、必利靈（bioallethrin)、必利靈 (bioallethrin)-S-環戊烯基、必赛靈(bioresmethrin)、乙氰 菊酯（cycloprothrin)、赛扶寧（cyfluthrin)(p-)、赛洛寧 (cyhalothrin)(Y_、λ·)、赛滅寧（cypermethrin)(a-、β-、Θ-、 6_)、赛芬寧（(^11如0也1111)[(1尺)-反式-異構物]、第滅寧 (deltamethrin)、第芬寧（dimefluthrin)、依普靈 (empenthrin)[(EZ)-(lR)-異構物]、益化利（esfenvalerate)、 依芬寧（etofenprox)、芬普寧（fenpropathrin)、芬化利 (fenvalerate)、福本賽寧（flucythrinate)、伏滅寧 (flumethrin)、福化利（fluvalinate)O)、海本斯 (halfenprox)、益普靈（imiprothrin)、滅伏特靈 (metofluthrin)、百滅寧（permethrin)、芬特寧 (phenothrin)[(lR)-反式異構物]、普烈靈(prallethrin)、普 伏靈(profluthrin)、除轰菊酯(pyrethrins(pyrethrum))、利 201138623 滅靈(resmethrin)、RU-15525、希拉芬(silafluofen)、特 伏靈(tefluthrin)、特滅靈(tetramethrin)[(lR)-異構物]、泰 滅寧(tralomethrin)、參伏靈(transfluthrin)與 ZXI 8901 ; 或DDT ;或美克氣(methoxychlor)。於驗激導性乙醯基 膽驗受體促效劑，例如：氯於驗類（chloronicotinyIs)， 例如：乙醯普（acetamiprid)、克利定(clothianidin) '第諾 芬（dinotefuran)、益達胺（imidacloprid)、尼普爛 (nitenpyram)、硫克比（thiacloprid)、賽速安 (thiamethoxam);或尼古丁。異位性乙醯基膽鹼受體調 節劑（促效劑），例如：速必辛類（Spinosyns)，例如：賜 特能（spinetoram)與賜諾殺(spinosad)。氯離子通道活化 劑’例如：抑滅克定類（avermectins)/美保黴素 (milbemycin) ’例如：艾滅克定(abamectin)、抑滅克定 (emamectin)苯曱酸鹽、利滅克定(lepimectin)與美保克定 (milbemectin)。幼保激素擬似物，例如：赫普靈 (hydroprene)、克普靈（kinoprene)、滅普靈（methoprene) 或吩克卡(fenoxycarb);必普芬(pyriproxifen)。其他非專 一（多重位置)抑制劑，例如：發煙劑，例如：曱基溴及 其他烧基鹵化物；或氣吡靈（chloropicrin);硫醯氟；硼 砂；酒石酸銻鉀鹽。選擇性同翅目攝食阻斷劑，例如： 必滅辛(pymetrozine)或伏卡滅(flonicamid)。蜗生長抑制 劑，例如：克芬辛（clofentezine)、地伏辛（diflovidazin)、 海賽唑(hexythiazox)、抑特唑(etoxazole)。昆蟲腸膜之 微生物瓦解劑，例如：蘇雲金芽胞桿菌以色列亞種 201138623 {Bacillus thuringiensis subspecies israelensis) ' 桿菌⑽年/zflehcwW、蘇雲金芽胞桿菌點澤亞種 {Bacillus thuringiensis subspecies aizawai) ' -¾. # ^ ^ ^ 桿菌庫斯塔基亞種（5沉///似i/zwrz>2g7_e似& subspecies 々wrWflh；；、蘇雲金芽胞桿菌殺蟲亞種It is known to be effective in controlling a wide range of fungal pathogens (see ΕΡ-Β-460575 and US-A-2005-0032903). Although it is known that trifluoro-sensitive has a positive effect on plant health and quality (eg, protein content in the valley - see Clark, DC (2003)" Agronomic effects of the effect of trifluoro-sensitive on the type and biochemistry of growing wheat. Some 6 201138623 morphological and biochemical effects of Trifloxystrobin in wheat growing"" Pflanzenschutz-Nachrichten Bayer 56 (2), 281-296; improving abiotic stress tolerance - see Freundorfer, I (2008) stress stress "Less stress - higher yield", Bayer CropScience Courier 2, 1 M3) 'But currently no understanding of trifluoro-sensitive may also be effective in reducing the frequency and / or intensity of fruit rot. In this case, the present invention is useful for the frequency and/or intensity of apical rot disease in 卞IA taj云伊月匕, and also relates to the use of difluoro-sensitive to reduce the frequency and/or intensity of fruit rot. In one aspect of the invention, the trifluoro-sensitive is particularly useful for reducing the frequency and/or yield of fruit rot in fruits (e.g., tomatoes, peppers, and eggplants). The horticultural crop according to the present invention includes the following crops: pumpkin, squash, squash, sorghum, sweet corn,:, sorghum, ornamental plants, herbs, edible herbs, tomatoes, and digoes Cucumber 1 dish 'beet, cabbage, cauliflower, ball = blue one, broccoli, kale branch, radish, kohlrabi, lu, and genus, carafe, apple, raspberry, grass, banana, c: peach :/,#Pomegranate, Feng t stone trough, garlic, pepper (: two coffee), radish, Yangtao, wood #, walnut, lemon, mango, shiitake, sapling, orange, papaya, ^. 'Pepper, passion fruit, ^, walnut, plum, pistachio, persimmon, grapefruit (grape pumping), yoko, glutinous rice, cranberry, gooseberry, hazelnut, kiwi, almond, peach, artichoke, pineapple , Blackberry, Cashew, Loutao, Ershi, Apricot, Citrus, Coconut, 201138623 Cantaloupe, and including its harvested products (such as: fruits and vegetables commonly referred to as fruits in this article). According to the present invention, the trifluoro-sensitive phase is applied at different growth stages from the flowering stage (i.e., during the period of complete flowering and functioning, and the flowering stage also refers to the beginning of the flowering stage). It is preferred to use trifluoro-sensitive when producing horticultural crops in the greenhouse. In one aspect of the invention, the 'trifluoro-sensitive system is used as a commercial formulation, and thus the formulation and other active compounds (eg, insecticides, attractants, disinfectants, fungicides, snails, nematicides) Agents, fungicides, growth regulating substances, herbicides, safeners, fertilizers or chemical substances and biological control agents (eg yeasts (Mebc/m/AovWa form a mixture, made into a use form. Special Advantageous mixed compounds are, for example, fungicides, such as: nucleic acid synthesis inhibitors, for example: benalaxyl, Bendall-M, bupirimate, clozylacon, desalination ( Dimethirimol), ethirimol, furaxaxyl, hymexazole, metalaxyl, statin-Μ, ofurace, oxadixyl And ox〇iin acid. Inhibitors of mitosis and cell differentiation, such as: benomyl, carbendazim, chlorophene, chlorfenazole, diethofencarb, °Ethaboxam, fuberida Zole), pencycuron, thiabendazole, thiophanate, thiophanate-methyl and sulphonamide 8 201138623 (zoxamide). Respiratory inhibitors, eg as CI - Diflumetorim of the respiratory inhibitor; bixafen, boscalid, carboxin, fenfuram, natale as CII-respiratory inhibitors (flutolanil), flUOpyram, furametpyr, furmecyclox, isopyrazam (cis-epimer racemate irs, 4SR, 9RS and anti- - epimerization racemate 1RS, 4SR, 9SR mixture), ruthenium (cis-epimer racemate 1RS, 4SR, 9RS), ruthenium (cis-differential) Heteromeric racemates 1R, 4S, 9R), ruthenium (cis-epimer racemate 1 S, 4R, 9S), ruthenium (trans-epise isomerization racemization) 1RS, 4SR, 9SR), ruthenium (trans-episo isomerization racemate 1R, 4S, 9S), and ruthenium (trans-epise isomerism racemate is, 4R, 9R) ), mepronil, Jia Dexin (0XyCarb0Xin) Penflufen, penthiopyrad, sedaxane, thifluzamide; as a CIII-respiratory inhibitor, amisulbrom, azoxystrobin, cypress Cyazofamid, dimoxystrobin, enestrobin, famoxad〇ne, fenamidone, fiuoxastr〇bin, ether vinegar (kresoxim-methyl), metophylline (metominostrobin), erysalamine (orysastrobin), picoxystr〇bin, pyraclostrobin, pyroXyStr〇bin , pyramitostrobin, pyridencarb, trifloxystrobin. A compound that can be used as a decoupling agent, for example: bin 2011, 23, binapacryl, dinocap, ferimzone, fluazinam, and meptyldinocap. ATP production inhibitors, such as: fentin acetate, fentin chloride, fentin hydroxide, and amino acid biosynthesis and/or protein biosynthesis inhibitors For example: andoprim, blasticidin Silthiofam-S, cyprodinil, kasugamycin, gibberellin hydrochloride hydrate, mepenipyrim ) and pyrimethanil. Signal transduction inhibitors such as fenpiclonil, fludioxonil and quinoxyfen. Lipid and membrane synthesis inhibitors such as biphenyl, chlozolinate, edifenphos, etridiazole, iodocarb, iprobenfos, iprodione ), isoprothiolane, procymidone, propamocarb, pemoca hydrochloride, pyrazophos, tolclofos-methyl and gram Ning (vinclozolin). Melamine biosynthesis inhibitors, such as: aldimorph, azaconazole, bitertanol, bromuconazole, sipkon. Cyproconazole, diclobutrazole, difenoconazole, diniconazole, diconazole-M, dodemorph, demethylacetate, epoxy gram beta Epoxiconazole, etaconzole, fenarimol, fenbuconazole, fenhexamide, fenpropidin, Fenfen 201138623 (fenpropimorph), volt Fluquinconazole, flurprimidol, flusilazole, flutriafol, furconazole, cis-concans, hexaconazole, Imazalil, imipenem sulfate, imibenconazole, ipconazole, metconazole, myclobutanil, naftifin, New: nuarimol, oxpoconazole, paclobutrazole, pefurazoate, penconazole, piperalin, prochloraz, Propiconazole, Psycheon sitting (p Rothioconazole), Pyributicarb, pyrifenox, quinconazole, simeconazole, spiroxamine, tebuconazole, terbinafin , tetraconazole, triadimefon, triadimenol, tridemorph, triflumizole, triforine, triticonazole, excellent Uniconazole, viniconazole and voriconazole. Cell wall synthesis inhibitors such as: benthiavalicarb, dimethomorph, flumorph, iprovalicarb, mandipropamid, granulidine (p〇ly〇) Xins), polyoxorim, (prothiocarb), validamycin A and valifenalate. Melanin synthesis inhibitors, such as: caproamide, diclocymet, fennelney 201138623 (fenoxanil), phthalide, pyrrazine (pyr〇qUii〇n) and three matches Tricyclazole. Compounds that can induce host defense, such as: acibenzolar-S-mercapto, is〇tianil, probenazole, and tiadinil. Compounds with multiple positions' such as: Bordeaux mixture, captafol, captan, chlorothalonil, copper naphthalate, copper oxide, copper oxychloride, Copper preparations such as: copper hydroxide, copper sulfate, dichlofluanid, dithianon, dodine, toxin free base, ferbam, fluorofolpet, Folpet, guazatine, heat-free net acetate, iminoctadine, iminoctadine albesilate, iminoctadine triacetate, |mancopper, mancozeb, maneb, metiram, zinc salt, oxine-copper, propamidine ), thiol zinc, propaneb, sulfur and sulfur preparations (including: calcium polysulfide), thiram, tolylfuanid, zineb and ziram. Other compounds, for example: 2,3-dibutyl-6-oxythieno[2,3-d]pyrimidin-4(3H)-one, (2Z)-3-amino-2-cyano-3- Ethyl phenylprop-2-enoate, N-[2-(l,3-dimercaptobutyl)phenyl]fluoro-1,3-didecyl-1H-pyrazole-4-carboxyguanamine , 3-(Difluoroindolyl)-1-indenyl-N-(3',4,5,-trifluorobiphenyl-2-yl)-1Η-indazole-4-carboxamide, 3- (difluoroindolyl)-N-[4-fluoro-2-(l,l,2,3,3,3-hexafluoropropoxy)phenyl]-1-indolyl-1H-pyrazole-4 - Carboxy 12 201138623 Stearic amine, (2E)-2-(2-{[6-(3-Ga-2-methylphenoxy)_5_fluoropyrimidine-cardio]oxy}phenyl)-2-( Methoxyimido)_N_methylacetamide, (2E)_2-{2_[({[(2e,3e)-4_(2,6^ phenyl)) _3_ene_2_ Subunit] Amino}oxy}methyl]phenyl}-2-(methoxyimino)-bromomethylacetamide, 2-chloro-N-(l,l,3-trimethyl·2,3 -dihydro-1H-indole-4.yl)pyridine_3_carboxamide, Ν-(3-ethyl-3,5,5-trimethylcyclohexyl)_3_(carbamimidino)-2- Hydroxybenzamide, 5-methoxy-2-methyl-4(2-{[({(1))-1-[3-(trifluoromethyl)phenyl]ethylidene) Oxy]methyl}phenyl)-2,4-dihydro-3Η-1,2,4-triazol-3-one, (2 Ε)-2_(methoxyimino)-oxime-methyl-2-(2-{[({(1)-[3_(trifluoromethyl)phenyl]ethylidene))) ] mercapto}phenyl)acetamide, (2Ε)_2_(decyloxyimido)-oxime-methyl-2-{2mail)-({1_[3_(trifluoromethyl)phenyl] Ethoxy}imido)indenyl]phenylindoleacetamide, (2E)-2_{2-[({[())-1-(3_{[(e)-1-fluoro_2_benzene) Ethyl bromide]oxy)phenyl)ethylidene] oxetyl}oxy)methyl]phenyl}·2_(decyloxyimido)mercaptoacetamide, 1-(4-phenylphenyl) ) 2 - (ih-1,2,4-triazol-1-yl)cycloheptanol, 1-(2,2-dimercapto-2,3-dihydro-1H-member-1-yl)_1H _ azole _5_ phthalic acid ester, N-ethyl-N-fluorenyl _N,-{2-mercapto-5-(trifluoromethyl)-4-[3-(tridecyl decyl) Propoxy]phenyl}aryleneaminocarbamide, N'-{5-(difluoroindolyl)-2-indenyl-4-[3-(trimethylsulfanyl)propoxy]benzene }}-N-ethyl-N-mercapto-indenyl decylamine, 1H-imidazole-^ quinone carboxythioate-{1-[(4-methoxyphenoxy)indolyl]_2, 2_Dimethylpropyl}, N-[2-(4_{[3_(4-Azincyl)propan-2-alkynyl]oxy}_3-methoxyphenyl)ethyl]- Ν2-(decylsulfonyl) amidoxime, 5_gas_7 _(4-曱13 201138623 base brigade bite small base)_6_(2,4,6_three gas stupid base crimes trisporin and 5-amino-1,3,4-嗟二峻-2- Mercaptan, propamocarb-fosetyl, 1H-imidazolecarboxylic acid 1[(4-nonyloxyoxy)indenyl]-2,2-dimercaptopropionyl Example (2)-tetrafluoroethoxy)benzyl]-3-(difluoroindolyl ϋ _4_ 竣 胺, 2 3 5 6-tetrachloro-4-(decylsulfonyl) pyridine, 2-butoxy_6_iodo_3_propyl-4Η_chromen-4-one, 2-phenylphenol and salts, 3_(difluoromethylbubumethyl-N-[2-(l,l , 2,2-tetrafluoroethoxy)phenyl]_ιη_π than salivation_4_treazone, 3,4,5-dichloro-0 ratio bite-2,6-monocarbonitrile, 3-[5-( 4-oxophenyl)_2,3-dimethylisoxazin-3-yl]anthracene, 3-ox-5-(4-phenylphenyl)_4_(2,6-difluorophenyl)- 6-methyl. Combining, 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)_3,6-diindenyl hydrazine, quinoline-8-phenol, quinoline-8-phenol sulfate (2:1), tebufloquin, 5-methyl-6-octyl-3,7-dihydro[1,2,4]triazino[l,5-a]e -7-amine, 5-ethyl-6-octyl-3,7-dihydro[1,2,4]triazino[l,5-a]. Bite 7-amine, xin. Arnicoctradin, benzoquinone. Benthiazole, bethoxazin, capsimycin, carvone, chinomethionate, chloroneb, cufraneb , cyfhifenamid, Cymoxanil, cyprosulfamide, dazomet, debacarb, dichlorophen, diclomezine , dicloran, difenzoquat, ginseng, diphenylamine, ecomat, ferimzone, flumetover , fluopicolid, fluendan 201138623 (fluoroimid), flusulfamide, flutianil, fosety 1-aluminium, ethoxyphosphine (fosety 1-calcium) ), fosetyl-sodium, hexachlorophenyl, irumamycin, isotianil, methasulphocarb, (2E)-2-{2-[( {cyclopropyl[(4-decyloxyphenyl)imido]indenyl}thio)indolyl]phenyl}-3-methoxypropionic acid 曱g, isocyanuric acid Kill Metrafenone, (5-chloro-2-indolyl-4-mercaptopyridin-3-yl)(2,3,4-trimethoxy-6-nonylphenyl)fluorenone, Mead Mildiomycin, tolnifanide, N-(4-benzophenanthryl)-3-[3-decyloxy-4-(prop-2-yn-1-yloxy)phenyl] Propylamine, N-[(4-chlorophenyl)(cyano)indolyl]-3-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]propanoid Amine, N-[(5-bromo-3-chloropyridin-2-yl)indolyl]-2,4-dichloropyridin-3-carboxamide, N-[l-(5-bromo-3- gas Pyridin-2-yl)ethyl]-2,4-dichloropyridin-3-carboxydecylamine, N-[ 1-(5->odor-3-chloro-10pyridin-2-yl)ethyl ]-2-Gas-4-Moth 0 is a bit of 3-mercaptoamine, Ν-{(Ζ)-[(cyclopropyldecyloxy)imino][6-(difluoromethoxy)- 2,3-Difluorophenyl]methyl}-2-phenylacetamide, Ν-{(Ε)-[(cyclopropyldecyloxy)imino][6-(difluorodecyloxy) )-2,3-difluorophenyl]indolyl}-2-phenylacetamidine, natamycin, nickel dimercaptodithiocarbamate, nitrothal-isopropyl Base, octhilinone, oxamocarb, oxyfenthiin, pentacene and its salts, σσ井-1--1-, Phenothrin, acid and its salts, propamocarb-fosetylate, propanosine-sodium, proquinazid, pyrrolnitrine, Quentozene, 5-amino-2-(1-indolyl 15 201138623 ethyl)-4-(2-mercaptophenyl)-3-o-oxo-2,3-dihydrosatellite Sulfuric acid S-prop-2-yl-1-yl S, tecloftalam, tecanazene, triazoxide, tricholamide, 5-gas -Ν'-Phenyl-Ν'-propan-2-free-1-yl-β-thiophene-2-sulfinyl carboxylate, cholestyramine (2&1*^111丨(^),]^- Methyl-2-(1-{[5-fluorenyl-3-(trimethyl))pyrazol-1-yl]ethenyl}piperidin-4-yl)-N-[(1R)-1 ,2,3,4-tetrahydronaphthalen-1-yl]-1,3-thiazole-4-carboxyguanamine, N-mercapto-2-(l-{[5-fluorenyl-3-(trifluoro)曱基)-1Η- ° than 唆-1-yl] ethyl ketone group.定冰))-N-(l,2,3,4-tetrahydronaphthalen-1-yl)-1,3-indole-4-carboxamide, 3-(difluoroindolyl)-fluorene-[ 4-fluoro-2-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]_1_indolyl-1Η-0 than 嗤-4-cyclodecylamine and {6-[( {[(1-Mercapto-1Η-tetradec-5-yl)(phenyl)indenyl]amino}oxy)indolyl]pyridin-2-yl}amine amanoate. In addition, insecticides, acaricides and nematicides such as: acetylcholinesterase (AChE) inhibitors such as: amine phthalates, such as: alanycarb, dexamethasone Aidicarb), bendiocarb, benfuracarb, bucksin (1)11〖〇〇&1^(^111), butoxybucacin (131^0巧(^1) (;^111), carbaryl, carb〇furan, carbosulfan, ethiofencarb, fenobucarb, formetanate ), furathiocarb, isoprocarb, metiocarb, methodyl, met〇icarb, 〇xamyl, 毕加(pirimicarb), Anthony (pr〇p0xur), thiodicarb, thiofanox, trjazamates, trimethoate 201138623 (trimethacarb), XMC and xylylcarb; Or organophosphates such as: acephate, azamethiphos, azinphos (-mercapto, ethyl), cadusafos, chlorethox Yfos), chlorfenvinphos, chlormephos, chlorpyrifos (-mercapto), coumaphos, cyanophos, demeton-S-曱基,大利松((^2^1011), diclofen ((^11101^05)/〇〇\^, didrotophos, dimethoate, dimethylvinphos, Disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, blessing Fosthiazate, heptenophos, isofenphos, 0-(decyloxythiocarbazide) isopropyl salicylate, isoxathion, marathon (malathion), mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, Oxydemeton - thiol, parathion (-methyl), phenthoate, phorate, phosalone, yis (phosmet), phosphamidon, phoxim, pirimiphos (-mercapto), profenofos, propetamphos, prothiofos, Pyraclofos, pyridaphenthion, quinalphos, speed volt 17 201138623 (sulfotep), tebupirimfos, temephos, terfufos, four Tetrachlorvinphos, thiometon, triazophos, triclofen and vamidothion. GAB A-gated gas ion channel antagonists 'for example. organochlorines, for example: chl〇rdane, endosulfan (a); or fiprols (phenyl) Pyrazoles, for example, ethiprole, fipronil, pyrafluprole and Pyripr〇le. Sodium channel modulator / voltage-dependent sodium channel blocker 'eg: pyrethroids, eg: acrinathrin, allethrin (d-cis-trans, d-trans ), bifenthrin, bioallethrin, bioallethrin-S-cyclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin P-), cyhalothrin (Y_, λ·), cypermethrin (a-, β-, Θ-, 6_), 赛芬宁 ((^11如0也1111)[( 1 foot)-trans-isomer], deltamethrin, dimefluthrin, empenthrin [(EZ)-(lR)-isomer], Yihuali ( Esfenvalerate), etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate O), Haibens Halfenprox), imiprothrin, metofluthrin, permethrin, phenothrin [(lR)-trans isomer], prallethrin, pu Volt (pro Fluthrin), pyrethrins (pyrethrum), leh 201138623 resmethrin, RU-15525, silafluofen, tefluthrin, tetramethrin [(lR)- Isomers], tramomethrin, transfluthrin and ZXI 8901; or DDT; or methoxychlor. For the detection of acetylcholine receptor agonists, for example: chloronicotinyIs, for example: acetamiprid, clothianidin 'dinotefuran, Yida Amine (imidacloprid), nitenpyram, thiacloprid, thiamethoxam; or nicotine. Atopic acetylcholine receptor modulators (agonists), such as Spinosyns, for example, spinetoram and spinosad. Chloride channel activators 'eg avermectins/milbemycin' eg e.g. abmectin, emamectin benzoate, rimidine (lepimectin) and milbemectin. Probiotic hormone mimics, such as: hydroprene, kinoprene, metoprene or fenoxycarb; pyriproxifen. Other non-specific (multiple position) inhibitors, such as: fuming agents, such as: mercapto bromide and other alkyl halides; or chloropicrin; sulfonium fluoride; borax; bismuth potassium tartrate. Selective Homopteran feeding blockers, for example: pymetrozine or flonicamid. Cochlear growth inhibitors, for example: clofentezine, diflovidazin, hexythiazox, etoxazole. Microbial disintegrator of insect gut membrane, for example: Bacillus thuringiensis subsp. israel 201138623 {Bacillus thuringiensis subspecies israelensis) ' Bacillus (10) year / zflehcwW, Bacillus thuringiensis subspecies aizawai ' -3⁄4. # ^ ^ ^ Bacillus substitutes (5 sinks / / / like i / zwrz > 2g7_e like & / subspecies 々 wrWflh;;, Bacillus thuringiensis subsp.

thuringiensis subspecies tenebrionis) 5 BT 質：CrylAb CrylAc CrylFa Oy2Ab、mCry3A Ory3Ab、Thuringiensis subspecies tenebrionis) 5 BT quality: CrylAb CrylAc CrylFa Oy2Ab, mCry3A Ory3Ab,

Cry3Bb、Cry34/35Abl 〇粒線體ATP合成酶抑制劑，例 如：地芬能(diafenthiuron);或有機錫殺蜗劑，例如：亞 赛錫（azocyclotin)、赛赫錫（cyhexatin)及芬塔錫 (fenbutatin)氧化物；或歐蜗多（propargite);特達芬 (tetradifon)。瓦解質子梯度之氧化性磷酸化反應之去偶 合劑，例如：克芬D比(chlorfenapyr)與DNOC。於驗激導 性乙醯基膽鹼受體通道阻斷劑，例如：本速達 (bensultap)、培丹(cartap)鹽酸鹽、硫克蘭（thiocylam)與 硫速伏納(thiosulfap-sodium)。幾丁質生合成抑制劑，第 〇型，例如：苯曱醢基脲類，例如：必賽伏(bistrifluron)、 克伏能(chlofluazuron)、地伏能(diflubenzuron)、伏賽能 福環脲（flucycloxuron)、氟芬隆（flufenoxuron)、赫姆能 (hexaflumuron)、利芬能（lufenuron)、利化能（novaluron)、 諾化能（noviflumuron)、苯伏隆（penfluron)、特速能 (teflubenzuron)與三伏能(triflumuron)。幾丁質生合成抑 制劑，第1型，例如：佈芬辛(buprofezin)。蜆變瓦解劑， 例如：赛麻辛（cyromazine)。脫皮激素促效劑/瓦解劑， 20 201138623 例如二醯基肼類’例如：克麻赛(chromafen〇zide)'赫芬 賽(halofenozide)、甲氧芬^meth〇xyfenozide)與特芬賽 (tebufenozide)。章魚胺激導性促效劑，例如：三亞蟎 (amitraz”粒線體複合物_ΠΙ電子傳遞抑制劑，例如： 海滅能(hydramethylnone)、亞克希（acequinocyl)或伏克 靈（fhiacrypyrim)。粒線體複合物4電子傳遞抑制劑，例 如：METI殺蜱蟎劑，例如：芬賽昆(fenazaquin)、芬普 赛滅（fenpyroximate)、普靈芬（pyrimidifen)、必達本 (pyridaben)、達芬必(tebufenpyrad)、特芬必(tolfenpyrad) 或魚藤精(rotenone)(Derris)。依賴電壓之鈉通道阻斷劑， 例如：英赛普（indoxacarb);滅伏美松(metaflmnizone)。 乙醯基-CoA叛酸酶之抑制劑，例如：季酮酸衍生物， 例如：螺克芬(spirodiclofen)與螺滅芬(spiromesifen);或 0比洛酮酸衍生物’例如：螺特滅(Spir〇tetramat)。粒線體 複合物-IV電子傳遞抑制劑，例如：膦類，例如：磷化 鋁、磷化鈣、膦及磷化鋅或氰化物。粒線體複合物_π 電子傳遞抑制劑，例如：氰必吩(cyenopyrafen)。蘭尼驗 (ryanodin)受體調節劑，例如：二醯胺類，例如：氯蒽 吡咯（chlorantraniliprole)(Rynaxypyr)、氰胺吡咯 (cyantraniliprole)(Cyazypyr)及氟苯二醯胺 (flubendiamide)。其他具有未知或未確定作用機轉之活 性成份’例如：查得定（azadirachtin)、安伏滅 (amidoflumet)、苯赛滅（benzoximate)、必芬赛 (bifenazate)、蟎離丹(chinomethionat)、克利得(cryolite)、 21 201138623 賽特芬（cyflumetofen)、大克蜗（dicofol)、伏速吩 (fluensulfone)、伏吩靈（flufenerim)、必達利（pyridalyl) 與必伏松（pyrifluquinazon);或下列一種已知活性化合 物：4-{[(6-溴吡啶-3-基）曱基](2-氟乙基）胺基}呋喃 -2(5H)·酮（自 WO 2007/115644 中已知）、4-{[(6·氟吡啶 -3-基）曱基](2,2-二氟乙基）胺基}呋喃-2(511)-酮（自買0 2007/115644 中已知）、4-{[(2-氣-1,3-噻唑-5-基）曱基](2-氟乙基）胺基}呋喃·2(5Η)_酮（自WO 2007/115644中已 知）、4-{[(6-氯°比啶-3-基）曱基](2·氟乙基）胺基}呋喃 -2(5Η)-酮（自 WO 2007/ 115644 中已知）、4-{[(6-氯吡啶 -3-基）曱基](2,2-二氟乙基)胺基}呋喃-2(5Η)-酮（自WO 2007/115644中已知）>4-{[(6-氣-5-氟吡啶-3-基）曱基](甲 基)胺基}呋喃-2(5Η)-酮（自WO 2007/115643中已知）、 4-{[(5,6-二氯吼啶-3-基）曱基](2-氟乙基）胺基}呋喃 -2(5H)-g同（自 WO 2007/115646 中已知）、4-{[(6-氣-5-氟 0比咬-3-基）曱基](環丙基）胺基}〇夫喃_2(5H)_酮（自WO 2007/115643中已知）、4-{[(6-氣吡啶-3-基）曱基](環丙 基）胺基}呋喃-2(5H)-酮（自EP-A-0 539 588中已知）、 4_{[(6-氣。比啶_3_基）曱基](曱基)胺基}吱。南_2(5H)_g同（自 ΕΡ-Α-0 539 588中已知）、[(6-氣吡啶_3·基）曱基](曱基) 氧離子基-λ4-亞硫烧基氰醯胺（自w〇 2007/149134中已 知）、[1-(6-氣t定-3-基）乙基](曱基）氧離子Α_λ4_亞硫烷 基氰醯胺（自WO 2007/149134中已知)及其非對映異構 物(A)及(B) 22 201138623Cry3Bb, Cry34/35Abl mitochondrial ATP synthase inhibitors, such as: diafenthiuron; or organotin snail agents, such as: azocyclotin, cyhexatin, and fenta (fenbutatin) oxide; or propargite; tetradifon. A decoupling agent that catalyzes the oxidative phosphorylation of a proton gradient, such as chlorfenapyr and DNOC. Inducing acetylcholine receptor channel blockers, such as: bensultap, cartap hydrochloride, thiocylam, and thiosulfap-sodium . Chitin biosynthesis inhibitors, type I, for example: benzoquinone ureas, for example: bistrifluron, chlofluazuron, diflubenzuron, flucycloxuron ), flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, penfluron, teflubenzuron With three volts (triflumuron). Chitin biosynthesis inhibitor, type 1, for example: buprofezin. Metamorphic decomposing agent, for example: cyromazine. Ecdysone agonist/disintegrator, 20 201138623 For example, diterpenoids such as: chromafenzide (halofenozide, methoxine ^meth〇xyfenozide) and tefenfenozide ). Octopamine-induced agonist, for example: amitraz mitochondrial complex ΠΙ ΠΙ electron transport inhibitors, such as: hydramethylnone, acequinocyl or fhiacrypyrim Mitochondrial complex 4 electron transport inhibitors, such as: METI acaricides, such as: fenazaquin, fenpyroximate, pyrimidifen, pyridaben, Tebufenpyrad, tolfenpyrad or rotenone (Derris). Voltage-dependent sodium channel blockers, such as: indoxacarb; metaflmnizone. Inhibitors of acetyl-CoA tacrotic enzymes, for example, quaternary acid derivatives, such as: spirodiclofen and spiromesifen; or 0 pironic acid derivatives 'for example: snail (Spir〇tetramat). Mitochondrial complex-IV electron transport inhibitors, such as phosphines, such as: aluminum phosphide, calcium phosphide, phosphine and zinc phosphide or cyanide. mitochondrial complex _π electron Delivery inhibitors, for example: cyenopyrafen. ryanodin Body regulators, for example: diamines, for example: chlorantraniliprole (Rynaxypyr), cyantraniliprole (Cyazypyr) and flubendiamide. Others have unknown or undetermined action Transferred active ingredients 'eg: azadirachtin, amidoflumet, benzoximate, bifenazate, chinomethionat, cryolite, 21 201138623 Cyflumetofen, dicofol, fluensulfone, flufenerim, pyridalyl and pyrifluquinazon; or one of the following known active compounds: 4 -{[(6-Bromopyridin-3-yl)indolyl](2-fluoroethyl)amino}furan-2(5H)·one (known from WO 2007/115644), 4-{[( 6·Fluoropyridin-3-yl)indolyl](2,2-difluoroethyl)amino}furan-2(511)-one (known from Buy 0 2007/115644), 4-{[( 2-oxo-1,3-thiazol-5-yl)indenyl](2-fluoroethyl)amino}furan·2(5Η)-one (known from WO 2007/115644), 4-{[ (6-chloro-pyridin-3-yl)indenyl](2·fluoroethyl Amino}furan-2(5Η)-one (known from WO 2007/115644), 4-{[(6-chloropyridin-3-yl)indolyl](2,2-difluoroethyl) Amino}furan-2(5Η)-one (known from WO 2007/115644)>4-{[(6-Ga-5-fluoropyridin-3-yl)indolyl](methyl)amino group } furan-2(5Η)-one (known from WO 2007/115643), 4-{[(5,6-dichloroacridin-3-yl)indolyl](2-fluoroethyl)amine } furan-2(5H)-g with (known from WO 2007/115646), 4-{[(6-gas-5-fluoro 0-buty-3-yl)indolyl](cyclopropyl)amine 〇 〇 喃 _2 2 (5H) ketone (known from WO 2007/115643), 4-{[(6-apyridin-3-yl)indolyl](cyclopropyl)amino}furan- 2(5H)-ketone (known from EP-A-0 539 588), 4_{[(6-gas). Bisidine_3_yl) fluorenyl](fluorenyl)amino}吱. South _2(5H)_g with (known from ΕΡ-Α-0 539 588), [(6-aeropyridine_3.yl) fluorenyl](fluorenyl) oxy-yl-λ4-sulfinyl Cyanamide (known from w〇2007/149134), [1-(6-gas t--3-yl)ethyl](indenyl)oxy ion Α_λ4_sulfinyl cyanamide (from WO It is known in 2007/149134) and its diastereomers (A) and (B) 22 201138623

(亦自WO 2007/H9134中獲知）、[(6-三氟曱基吡啶-3- 基）曱基](曱基）氧離子基-λ4-亞硫烷基氰醯胺（自WO 2007/095229 中已知）或速伏樂（sulfoxaflor)(亦自 WO 2007Π49134 中已知）、11-(4-氣-2,6-二曱基苯基)-12-羥 基-1,4-二氧雜-9-氮雜二螺[4.2.4.2]十四碳-11-烯-10-酮 (自％0 2006/089633 中已知）、3-(4'-氟-2,4-二曱基聯苯 -3-基)-4-輕基-8-氧雜-1-氮雜螺[4.5]癸-3-婦-2-銅（自 WO 2008/067911 中已知）及 1-{2,4-二甲基-5-[(2,2,2-三 氟乙基）亞石黃廳基]笨基}-3-(三敗曱基)-1H-1，2,4-三唾（自 WO 1999/55668 中已知）。 此外’適合混合之化合物說明於例如：Weed(also known from WO 2007/H9134), [(6-trifluoromethylpyridin-3-yl)indolyl](indenyl)oxy ionyl-λ4-sulfinylcyanamide (from WO 2007/ Known in 095229) or sulfoxaflor (also known from WO 2007Π49134), 11-(4-gas-2,6-diamidinophenyl)-12-hydroxy-1,4-dioxo Hetero-9-azaspiro[4.2.4.2]tetradec-11-ene-10-one (known from %0 2006/089633), 3-(4'-fluoro-2,4-dioxin Benzyl-3-phenyl)-4-lightyl-8-oxa-1-azaspiro[4.5]indole-3-indol-2-copper (known in WO 2008/067911) and 1-{ 2,4-Dimethyl-5-[(2,2,2-trifluoroethyl) sulphate]] stupid}-3-(trisinyl)-1H-1,2,4- Three saliva (known in WO 1999/55668). Further, the compounds suitable for mixing are described, for example, in Weed.

Research 26, 441-445 (1986)或"農藥手冊(The PesticideResearch 26, 441-445 (1986) or "Pesticide Manual (The Pesticide

Manual)" ’第13版，英國作物保護學會及皇家化學會 (The British Crop Protection Council and the Royal Soc. of Chemistry)，2003及其中摘錄之文獻’其可作為例 如.乙醯乳酸合成酶、乙醯基_€〇八_羧酸酶、纖維素-合 成酶、烯醇丙酮莽草酸_3_磷酸-合成酶、鞑醯胺_合成 酶、對羥基苯基丙綱酸-二氧化酶、八氫茄紅素去飽和 酶、光合作用系統ί、光合作用系統II及/或原卟啉原_ 氧化酶之抑制劑。 23 201138623 可自文獻中已知且可與根據本發明化合物組合之 可作為除草劑或植物生長調節劑之活性化合物實例可 述及下列： 乙酿拉草（acetochlor)、阿拉酸式苯（acibenzolar)、 S-曱基阿拉酸式苯、亞喜芬(acifluorfen)、亞喜芬鋼、艾 克芬(aclonifen)、拉草（alachlor)、（allidochlor)、艾殺定 (alloxydim)、艾殺定鈉' 草殺淨（ametryne)、安卡松 (amicarbazone)、安得祿（amidochlor)、醯胺速能 (amidosulphuron)、安必烈（aminopyralid)、胺基三唑 (amitrole)、胺基績酸铵(ammoniumsulfamat)、氯苯β密咬 醇(ancymidol)、安弗斯(anii〇fos)、亞速爛（asulam)、草 脫淨（atrazine)、赛芬定（azafenidin)、金速能 (azimsulphuron)、疊氮津（aziprotryn)、BAH-043、 BAS-140H、BAS-693H、BAS-714H、BAS-762H、 BAS-776H、BAS-800H、本伏醢胺(beflubutamid)、本索 靈（benazolin)、乙基本索靈、本卡松(bencarbazone)、氟 草胺（benfluralin)、咬草石黃（benfuresate)、地散磷 (bensulide)、免速隆（bensuiphuron-methyl)、本達松 (bentazon)、本狄松（benzfendizone)、本克隆 (benzobicyclon)、草酮（benzofenap)、本索氟（benzofluo)、 本索普（benzoylprop)、必芬諾（bifenox)、必拉伏斯 (bialafos)、必拉伏斯鈉、雙草鱗(biSpyribac)、雙草崎納、 克草（bromacil)、>臭芬諾（bromobutide)、漠紛月亏 (bromofenoxim)、>臭尼（brom〇Xynii)、漠能(bromuron)、 24 201138623 佈滅伏斯(buminafos)、經草酮（busoxinone)、丁基拉草 (butachlor)、本芬希(butafenacil)、抑草構(butamifos)、 丁烯草胺（butenachlor)、比達寧（butralin)、佈希定 (butroxydim)、拔敵草（butylate)、卡芬唑（cafenstrole)、 卡酸胺（carbetamide)、卡芬松(carfentrazone)、乙基卡芬 松（carfentrazone-ethyl)、克美希芬（chlomethoxyfen)、克 爛本(chloramben)、炔禾靈（chlorazifop)、丁基快禾靈、 氣溴能（chlorbromuron)、氯炔靈（chlorbufam)、伐草克 (chlorfenac)、伐草克鈉、克吩普（chlorfenprop)、氯曱丹 (chlorflurenol)、曱基氯甲丹、克達松(chloridazon)、氣 嘧石黃隆（chlorimuron)、乙基氣嘧橫隆、錄壯素 (chlormequat-chlorid)、克石肖芬（chlornitrofen)、惡草酉同 (chlorophthalim)、二曱基敵草索(chlorthal-dimethyl)、氣 特能（chlortoluron)、氯速能（chlorsulfuron)、辛丹 (cinidon)、乙基辛丹（cinidon-ethyl)、辛滅寧 (cinmethylin)、辛速能(cinosulfuron)、克定(clethodim)、 克定普（clodinafop)、 炔丙基克定普 (clodinafop-propargyl)、殺雄。秦酸（clofencet)、克麻松 (clomazone)、克普（clomeprop)、調果酸(cloprop)、克比 賴（clopyralid)、克速爛（cloransulam)、曱基克速爛 (cloransulam-methyl)、克有龍（cumyluron)、氰酿胺、賽 淨（cyanazine)、環丙蕴草胺（cyclanilide)、賽克 (cycloate)、賽速姆能（cyclosulfamuron)、賽克定 (cycloxydim)、賽有隆(cycluron)、賽赫普（cyhalofop )、 25 201138623 丁基賽赫普（cyhalofop-butyl)、賽伯刈（cyperquat)、環丙 津(cyprazine)、三環塞草胺(cyprazole)、2,4-D、2,4-DB、 汰草龍(daimuron)/殺草隆(dymron)、得拉本(dalapon)、 丁酰耕(daminozide)、邁隆(dazomet)、正癸醇、得滅芬 (desmedipham)、敵草淨(desmetryn)、地特希σ比°坐酸鹽 (detosyl-pyrazolate)(DTP)、達烈（diallate)、汰克草 (dicamba)、二氣普（dichlorprop)、二氯普-P、大克 (diclofop)、曱基大克(diclofop-methyl)、曱基大克-P、大 克爛（diclosulam)、乙曱草胺(diethatyl)、乙基乙曱草胺、 枯莠隆（difenoxuron)、大芬克（difenzoquat)、大伏肯 (diflufenican)、二氟芬吡(diflufenzopyr)、二氟芬吡鈉、 大滅能（dimefuron)、敵草克納（dikegulac-sodium)、大滅 能（dimefuron)、大滅普（dimepiperate)、大滅克 (dimethachlor)、大滅淨（dimethametryn)、大滅醯胺 (dimethenamid)、大滅酿胺-P、穫萎得(dimethipin)、二 曱速隆(dimetrasulfuron)、二硝胺（dinitramine)、達諾殺 (dinoseb)、特樂酚(dinoterb)、大芬滅(diphenamid)、異 丙淨（dipropetryn)、達快（diquat)、二溴達快、二硫吡 (dithiopyr)、達有龍（diuron)、DNOC、甘草津 (eglinazine-ethyl)、茵多酸（endothal)、EPTC、依普卡 (esprocarb)、依伏靈（ethalfluralin)、曱基依滅速能 (ethametsulphuron-methyl)、益收（ethephon)、石黃嗟隆 (ethidimuron)、乙草酮（ethiozin)、依滅賽（ethofumesate)、 乙氧呋草黃(ethofumesate)、依特芬(ethoxyfen)、乙基依 26 201138623 特芬、乙氧速能（ethoxysulfuron)、依本賽(etobenzanid)、 F-5331 ’ 亦即 N-[2-氯-4-氟-5-[4-(3-氟丙基)-4,5-二氫-5-側氧基-1H-四唾-1-基]-苯基]-乙續酿胺、；：弟丙酸 (fenoprop)、芬賽普（fenoxaprop)、芬賽普-p、乙基芬賽 普、乙基芬賽普-p、芬賽醯胺（fentrazamide)、非草隆 (fenuron)、伏爛普（flamprop)、間異丙基伏爛普、間曱 基伏爛普、伏速能（flazasulphuron)、伏速爛 (florasulam)、伏寄普（fluazifop)、伏寄普-p、丁 基伏寄 普、丁基伏寄普-p、伏唾烈（fluazolate)、伏卡松 (flucarbazone)、伏卡松鈉、氟°比續隆（flucetosulfuron)、 貝殺靈（fluchloralin)、伏芬賽（flufenacet)(σ塞伏醯胺 (thiafluamide)、氟噠草酯（flufenpyr)、乙基氟噠草酯、 氟節胺（flumetralin)、伏速爛（flumetsulam)、伏克能 (flumiclora)、戊基伏克能、伏克辛（flumioxazin)、伏普 平（flumipropyn)、伏特能（fluometuron)、伏地吩 (fluorodifen)、氣克芬(fluoroglycofen)、乙基氟克芬、伏 普散（flupoxam)、伏帕希（flupropacil)、氟丙酸 (flupropanate)、伏普速能（flupyrsulfuron)、曱基伏普速 能鈉、伏能（flurenol)、丁基伏能、伏利酮（fluridone)、 氟口各草酮(flurochloridone)、氟氯比（fluroxypyr)、曱基庚 基氟氯比(fluroxypyr-meptyl)、伏比朵（flurprimidol)、氟 它蒙(flurtamone)、伏賽特(fluthiacet)、曱基伏賽特、伏 賽醯胺（fluthiamide)、伏賽芬（fomesafen)、伏拉速能 (foramsulphuron)、福芬素（forchlorfenuron)、調節膦 27 201138623 (fosamine)、吱氧草 _i (furyloxyfen)、偽赤黴酸 (gibberellinicacid)、草銨膦(glufosinate)、1-草錢膦、ι_ 草銨膦銨、草甘膦(glyphosate)、異丙銨草甘膦、Η-92(Π、 赫賽芬(halosafen)、合速隆(halosulfuron)、曱基合速隆、 合氣氟(haloxyfop)、合氯氟-p、乙氧乙基合氯氟、乙氧 乙基合氯氟-P、曱基合氣氟、曱基合氣氟-p、菲殺淨 (hexazinone)、HNPC-9908、HOK-2(H、HW-02、咪草酸 (imazamethabenz)、曱基咪草酸、曱氧味草終 (imazamox)、曱基咪草克（imazapic)、依滅草（imazapyr)、 口米口坐啥琳酸（imazaquin)、°米草煙（imazethapyr)、依速隆 (imazosulfuron)、抗倒胺（inabenfide)、依達諾芳 (indanofan)、吲哚乙酸(IAA)、4-吲哚-3-基-丁酸(IBA)、 碘磺隆(iodosulfuron)、曱基碘磺隆鈉、块苯腈(i〇Xynii)、 丁 肺醯胺（isocarbamid)、異樂靈（isopropalin)、異丙隆 (isoproturon)、異惡隆（isouron)、異噁草胺（isoxaben)、 異惡氣草酮（isoxachlortole)、異噁唑草酮（isoxaflutole)、 異惡草鍵（isoxapyrifop)、IDH-100、KUH-043、 KUH-071、卡靈草（karbutilate)、克多草（ketospiradox)、 乳氟禾草靈（lactofen)、環草定（lenacil)、理有龍 (linuron)、馬來酸酿肼(maleinic acid hydrazid)、MCPA、 MCPB、MCPB-曱基、MCPB-乙基與 MCPB 鈉、二曱 四氯丙酸(mecoprop)、二曱四氣丙酸鈉、二曱四氣丙酸 丁氧乙酯、二曱四氣丙酸-p_丁氧乙酯、二曱四氣丙酸-P-二甲基銨、二曱四氯丙酸-P-2-乙基己酯、二曱四氣丙酸 28 201138623 -p-鉀、滅芬草(mefenacet)、美福泰(mefluidide)、曱略。翁 (mepiquat-chlorid)、曱續胺確隆(mesosulfuron)、曱基曱 石黃胺石黃隆、硝草嗣（mesotrione)、曱基苯σ塞隆 (methabenzthiazuron)、斯美地（metam)、°号唾草胺 (metamifop)、笨草酮（metamitron)、滅草胺 (metazachlor)、滅草定（methazole)、開滅草 (methoxyphenone)、曱基殺草隆(methyldymron)、1-曱基 環丙烯、異硫氰酸曱S旨、。比喃隆(metobenzuron)、演谷 隆(metobromuron)、莫多草(metolachlor)、左旋莫多草 (s-metolachlor)、石黃草嗤胺（metosulam)、曱氧隆 (metoxuron)、滅必淨(metribuzin)、曱確隆(metsulfuron)、 曱基曱石黃隆、稻得壯(molinate)、庚草胺(monalide)、單 腺 （Monocarbamide )、 硫酸二氫單脲 (Monocarbamide-dihydrogensulphate ) 綠谷隆 (monolinuron)、單。密續隆（monosulfuron)、滅草隆 (monuron)、MT 128、MT-5950，亦即 N-[3-氯-4-(1-曱基 乙基）-苯基]-2-曱基戊醯胺、NGGC-011、奈普 (naproanilide)、滅落脫（napropamide)、納得爛 (naptalam)、NC-310,亦即 4-(2,4-二氯苯曱醯基)-1-曱基 -5-苯曱基氧°比唾、草不龍（neburon)、煙嘴石黃隆 (nicosulfuron)、°比氣草胺（nipyraclofen)、滅殺草 (nitralin)、護谷（nitrofen)、瑣基苯紛鈉 (nitrophenolat-sodium)(異構物之混合物）、硝基苯甲醚 (nitrofluorfen)、壬酸、達草滅（norflurazon)、坪草丹 29 201138623 (orbencarb)、嘧苯胺續隆(orthosulfamuron)、消草石黃靈 (oryzalin)、快噁草酮（oxadiargyl)、樂滅草（oxadiazon)、 環氧嘧磺隆（oxasulfuron)、惡草酮（oxaziclomefone)、復 祿芬（oxyfluorfen)、巴克素（paclobutrazol)、巴拉別 (paraquat)、二氣巴拉別（paraquat-dichlorid)、壬酸、施 得圃（pendimethalin)、本達靈（pendralin)、平速爛 (penoxsulam)、曱氣草胺（pentanochlor)、環戊惡草酮 (pentoxazone)、佈福松（perfluidone)、烯草胺 (pethoxamid)、棉胺寧（phenisopham)、甜菜寧 (phenmedipham)、乙基甜菜寧、毒莠定(pid〇ram)、氟吡 醯草胺（picolinafen)、唑啉草酯（pin〇xaden)、草麟 (piperophos)、必吩諾普(pirifenop)、丁基必吩諾普、普 拉草(pretilachlor)、氟嘧磺隆(primisulfuron)、曱基氟。密 確隆、撲殺熱(probenazole)、氟峻草胺（profluazol)、環 丙腈津(procyazine)、氨氟樂靈(prodiamine)、普氟樂靈 (prifluraline) > 環苯草酮（profoxydim)、調環酸 (prohexadione)、調環酸鈣、茉莉酸丙醋 (prohydrojasmone)、撲滅通（prometon)、撲草淨 (prometryn)、雷蒙得(propachlor)、敵稗(propanil)、普拔 草（propaquizafop)、普拔根（propazine)、苯胺靈 (propham)、異丙草胺（propisochlor)、丙氧基卡巴膝 (propoxycarbazone)、丙氧基卡巴腙鈉、戊炔草胺 (propyzamide)、曱硫石黃樂靈（prosulfalin)、苄草丹 (prosulfocarb)、氟石黃隆（prosulfuron)、丙炔草胺 201138623 (prynachlor)、雙唑草（pyraclonil)、吡草醚(pyraflufen)、 乙基°比草鱗、石黃醯草°比峻（pyrasulfotole)、°比哇特 (pyrazolynate)(苄草唑（pyrazolate))、乙基百速隆 (pyrazosulfuron-ethyl)、普芬草（pyrazoxyfen)、百草枯 (pyribambenz)、異丙基百草枯、嘧啶肟草醚 (pyribenzoxim)、稗草畏（pyributicarb)、吡達伏 (pyridafol)、必汰草(pyridate)、環酯草醚(pyriftalid)、嘧 草謎（pyriminobac)、曱基《密草_、口密咬硫蕃 (pyrimisulfan)、《密硫草醚(pyrithiobac)、。密硫草醚鈉、殺 草石風(pyroxasulfone)、曱氧績草胺(pyroxsulam)、快克草 (quinclorac)、氯曱喹琳酸（quinmerac)、滅藻酿i (quinoclamine)、快伏草（quizalofop)、乙基快伏草、快 伏草-p、乙基快伏草-p、糖草醋（quizalofop-p-tefuryl)、 玉嘧磺隆（rimsulfuron)、密草通（secbumeton)、西殺草 (sethoxydim)、環草隆(siduron)、草滅淨(simazine)、西 草淨(simetryn)、SN-106279、磺草酮(sulcotrione)、菜草 畏(sulfallate)(cdec)、甲石黃草胺(sulfentrazone)、曱嘧石黃隆 (sulfometuron)、曱基曱嘧石黃隆、草硫膦(sulfosate)(草甘 膦-三甲基硫鹽）、磺胺磺隆（sulfosulfuron)、SYN-523、 SYP-249、SYP-298、SYP-300、牧草胺(tebutam)、丁噻 隆（tebuthiuron)、四氣硝基苯（tecnazene)、特伏三酮 (tefuryltrione)、硝磺草酮（tembotrione)、得殺草 (tepraloxydim)、特草定(terbacil)、特草靈（terbucarb)、 特丁草胺(terbuchlor)、曱氧去草淨(terbumeton)、草淨津 31 201138623 (terbuthylazine)、特丁净（terbutryn)、th-547、欣克草 (thenylchlor)、賽氟滅（thiafluamide)、噻氟隆 (thiazafluron)、噻草啶（thiazopyr)、噻二唑草胺 (thidiazimin)、噻苯隆（thidiazuron)、噻吩卡巴腙 (thiencarbazone)、曱基°塞吩卡巴腙、。塞石黃隆 (thifensulfuron)、曱基噻石黃隆、噻氟菌胺(thiobencarb)、 仲草丹（tiocarbazil)、》比草石黃（t〇pramezone)、肪草酮 (tralkoxydim)、野麥畏（triallate)、醚苯續隆 (triasulfuron)、三氟草胺（triaziflam)、三唑吩醯胺 (triazofenamide)、苯磺隆(tribenuron)、曱基苯磺隆、三 氣乙酸(tea)、三氯比（triclopyr)、三地芬(tridiphane)、草 達津(trietazine)、三氟咬石黃隆(trifloxysulfuron)、三敗口定 續隆納、三福林(trifluralin)、氟胺續隆(triflusulfuron)、 曱基氟胺石黃隆、三曱隆（trimeturon)、抗倒酉旨 (trinexapac)、乙基抗倒g旨、三氟曱石黃隆(tritosulfuron)、 地得福(tsitodef)、烯效唾(uniconazole)、烯效唾-p、滅草 猛（vernolate)、ZJ-0166、ZJ-0270、ZJ-0543、ZJ-0862， 及下列化合物Manual) " '13th edition, The British Crop Protection Council and the Royal Soc. of Chemistry, 2003 and the extracts thereof' can be used as, for example, acetamidine lactate synthase,醯 醯 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Inhibitors of phytoene desaturase, photosynthesis system, photosynthesis system II and/or protoporphyrinogen oxidase. 23 201138623 Examples of active compounds which are known from the literature and which can be combined with the compounds according to the invention as herbicides or plant growth regulators can be mentioned as follows: acetochlor, acibenzolar , S-hydrazide benzene, acifluorfen, axifen, aclonifen, alachlor, allidochlor, alloxydim, azodendron 'Ametryne, amicarbazone, amidochlor, amidosulphuron, aminopyralid, amitral, amino acid ammonium (ammoniumsulfamat), chlorobenzene β ancymidol, anii〇fos, asulam, atrazine, azafenidin, azimsulphuron , aziprotryn, BAH-043, BAS-140H, BAS-693H, BAS-714H, BAS-762H, BAS-776H, BAS-800H, beflubutamid, benazolin , ethyl benzoxine, benzcarbazone, benfluralin, bituminous stone (benfu) Resate), bensulide, bensuiphuron-methyl, bentazon, benzfendizone, benzobicyclon, benzofenap, benzofluo ), benzoylprop, bifenox, bialafos, birafus sodium, biSpyribac, biscax, bromacil, > stinky Bromobutide, bromofenoxim, >brom〇Xynii, bromuron, 24 201138623 buminafos, busoxinone, butyl Butachlor, butafenacil, butamifos, butenachlor, butralin, butroxydim, butarate, carfen Caffestrole, carbeamide, carfentrazone, carfentrazone-ethyl, chlomethoxyfen, chloramben, chlorazifop , butyl chlorhexidine, chlorbromuron, chlorbufam, valac (chlorfenac), oxafenac, chlorfenprop, chlorflurenol, mercaptochloromethyl chlordane, chloridazon, chlorimuron, ethyl acesulfame Chlormequat-chlorid, chlornitrofen, chlorophthalim, chlorthal-dimethyl, chlortoluron, chlorsulfuron , cinidon, cinidon-ethyl, cinmethylin, cinosulfuron, clethodim, clodinafop, propargyl ketidine (clodinafop-propargyl), killing males. Clofencet, clomazone, clomeprop, cloprop, clopyralid, cloransulam, cloransulam-methyl , cumyluron, cyanogenic amine, cyanazine, cyclanilide, cycloate, cyclosulfamuron, cycloxydim, race Cyclaron, cyhalofop, 25 201138623 cyhalofop-butyl, cyperquat, cyprazine, cyprazole, 2, 4-D, 2,4-DB, daimuron/dymron, dalapon, daminozide, dazome, n-decyl alcohol, extinction Desmedipham, desmetryn, detosyl-pyrazolate (DTP), dialate, dicamba, dichlorprop, Dichloropro-P, diclofop, diclofop-methyl, decyl-gram-P, diclosulam, diethatyl, ethyl acetochlor Dry Difenoxuron, difenzoquat, diflufenican, diflufenzopyr, diflufenazone, dimefuron, dikegulac-sodium, Dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, big tyranamine-P, dimethipin, Dimetrasulfuron, dinitramine, dinoseb, dinoterb, diphenamid, dipropetryn, diquat, two Bromodine, dithiopyr, diuron, DNOC, eglinazine-ethyl, endothal, EPTC, esprocarb, ethalfluralin , ethametsulphuron-methyl, ethephon, ethidimuron, ethiozin, ethofumesate, ethofumesate, et Ethylphene, ethyl phthalate 26 201138623 Teflon, ethoxysulfuron, yi Etobenzanid, F-5331 ', ie N-[2-chloro-4-fluoro-5-[4-(3-fluoropropyl)-4,5-dihydro-5-sideoxy-1H- Tetras-l-yl]-phenyl]-ethyl continuation amine;:: fenoprop, fenoxaprop, fensetrol-p, ethyl fenset, ethyl fenset -p, fentrazamide, fenuron, flamprop, isopropyl volta, sulphate, flazasulphuron, volts (florasulam), fluazifop, voltapyl-p, butyl voltapod, butyl volt-p-p, fluazolate, flucarbazone, vokasone, Flucetosulfuron, fluchloralin, flufenacet (thiafluamide, flufenpyr, ethyl flufenate, flubenzamide) (flumetralin), flumetsulam, flumiclora, amyl voltaic, flumioxazin, flumipropyn, fluometuron, fluorodifen, Fluoroglycofen, ethyl flufen, fupu (flupoxam), flupropacil, flupropanate, flupyrsulfuron, sulphonic sodium, fluranol, butyl voltamate, fluridone ), flurochloridone, fluroxypyr, fluroxypyr-meptyl, flurprimidol, flurtamone, fluthiacet ), 曱基伏特特, fluthiamide, fomesafen, foramsulphuron, forchlorfenuron, phosphine 27 201138623 (fosamine), 吱 草 _ i (furyloxyfen), gibberellinic acid, glufosinate, 1-pharytidine, iota glufosinate, glyphosate, isopropyl glyphosate, thorium-92 ( Π, halosafen, halosulfuron, hydrazine sulfonate, haloxyfop, chlorofluoro-p, ethoxyethyl chlorofluoro, ethoxyethyl chlorofluoro -P, sulfhydryl fluoride, sulfhydryl fluoride-p, hexazinone, HNPC-9908, HOK-2 (H, HW-02, imazamethabenz)曱 咪 草 oxalate, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, yizethapyr Izosulfuron, inabenfide, indanofan, indole acetic acid (IAA), 4-indol-3-yl-butyric acid (IBA), iodosulfuron, Sodium iodosulfuron sodium, block benzonitrile (i〇Xynii), isocarbamid, isopropalin, isoproturon, isouron, isoxachlor ( Isoxaben), isoxachlortole, isoxaflutole, isoxapyrifop, IDH-100, KUH-043, KUH-071, karbutilate, keto grass (ketospiradox), lactofen, lenacil, linuron, maleinic acid hydrazid, MCPA, MCPB, MCPB-mercapto, MCPB-B And MCPB sodium, mecoprop, sodium tetradecylpropionate, butane ethyl tetrapropionate, p-butoxyethyl ester, diterpenic acid Tetrapropionic acid-P-dimethylammonium, di-tetrachloropropionic acid-P-2-ethylhexyl ester, diterpene tetrapropionic acid 28 201138623 -p-potassium, mefenacet, mefu Thai (mefluidide), strategy. Mepiquat-chlorid, mesosulfuron, fluorenyl-pyroxanthin, mesotrione, methabenzthiazuron, metam, °metamifop, metamitron, metazachlor, methazole, methoxyphenone, methyldymron, 1-mercapto Cyclopropene, guanidinium isothiocyanate S. Metobenzuron, metobromuron, metolachlor, s-metolachlor, metosulam, metaxuron, extinction (metribuzin), metsulfuron, sulfhydryl sulphate huanglong, rice sulphate, monoalide, monocarbamide, monocarbamide-dihydrogensulphate Long (monolinuron), single. Monosulfuron, monuron, MT 128, MT-5950, ie N-[3-chloro-4-(1-mercaptoethyl)-phenyl]-2-mercapto Indoleamine, NGGC-011, naproanilide, napropamide, naptalam, NC-310, ie 4-(2,4-dichlorobenzoinyl)-1-pyrene Base-5-phenylhydrazine oxygen ° than saliva, neburon, nicosulfuron, nipyraclofen, nitrin, nitrofen, trivial Nitrophenolat-sodium (mixture of isomers), nitrofluorfen, citric acid, norflurazon, pingcaodan 29 201138623 (orbencarb), cumene extended ( Orthosulfamuron), oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, Paclobutrazol, paraquat, paraquat-dichlorid, tannic acid, pendimethalin, pendralin, penoxsulam, hernia Pentanochlor, pentoxazone, perfluidone, pethoxamid, phenisopham, phenmedipham, ethyl beetine, chlorpyrifos Ram), picolinafen, pinoxaxapin, piperophos, pirifenop, butyl bunoptox, pretilachlor, Primisulfuron, fluorenyl fluoride. Mimethoate, probenazole, profluazol, procyazine, prodiamine, prifluraline > profoxydim , prohexadione, calcium cyclamate, prohydrojasmone, prometon, prometryn, propachlor, propanil, puppies (propaquizafop), propazine, propham, propisochlor, propoxycarbazone, propoxycarbazone, propyzamide, guanidine Prosulfain, prosulfocarb, prosulfuron, propargyl 201138623 (prynachlor), pyraclonil, pyraflufen, ethyl Scale, scutellaria, pyraulfotole, pyrazolynate (pyrazolate), pyrazoosulfuron-ethyl, pyrazoxyfen, paraquat ( Pyribambenz), isopropyl paraquat, pyribenzoxim, Pyributicarb, pyridafol, pyridate, pyrifalid, pyriminobac, 曱基《密草_, 密密咬密(pyrimisulfan) , "pyrithiobac", . Sodium thiosulfate, pyroxasulfone, pyroxsulam, quinclorac, quinmerac, quinoclamine, quick grass (quizalofop), ethyl quick grass, fast grass-p, ethyl quick-grass-p, quizalofop-p-tefuryl, rimsulfuron, secbumeton, Sethoxydim, siduron, simazine, simetryn, SN-106279, sulcotrione, sulfallate (cdec), A Sulfentrazone, sulfometuron, sulfhydryl sulfonium, sulfosate (glyphosate-trimethylsulfate), sulfosulfuron, SYN-523, SYP-249, SYP-298, SYP-300, tebutam, tebuthiuron, tecnazene, tefuryltrione, mesotrione (tembotrione) ), tepraloxydim, terbacil, terbucarb, terbuchlor, terbumeton, grass net 31 2011 38623 (terbuthylazine), terbutryn, th-547, thenylchlor, thiafluamide, thiazafluron, thiazopyr, thiadiazolamide Thidiazimin), thidiazuron, thiencarbazone, thiophene thiophene carbazide. Thifensulfuron, thiophene sulphate, thiobencarb, tiocarbazil, t〇pramezone, tralkoxydim, wild wheat Triallate, triasulfuron, triaziflam, triazofenamide, tribenuron, mercaptosulfuron, triacetic acid (tea), Triclopyr, tridiphane, trietazine, trifloxysulfuron, trisodium sulphate, trifluralin, fluamine (triflusulfuron), guanyl fluoromethine huanglong, trimeturon, trinexapac, ethyl anti-reverse g, tritosulfuron, tsitodef , uniconazole, ene-salt-p, vernolate, ZJ-0166, ZJ-0270, ZJ-0543, ZJ-0862, and the following compounds

32 20113862332 201138623

俗名係依據國際標準組織（Intemati〇nal Organization for Standardizati〇n (IS〇))或化合物之化學 名稱(若適當時，與習知之代碼—起使用）使用，且總是 包括所有適用之型式’如：酸類、鹽類、酯類或其修飾 型，如：異構物，如：立體異構物及光學異構物。可述 及至少一種適用之型式及/或修飾型作為實例。 當根據本發明方法使用時，依據施用途徑而定，三 氟敏之施用率可以在相當大範圍内變化。根據本發明化 合物於處理植物植株(例如：葉部）時之施用率為0.1至 10 000 g/ha，較佳為1至1000 g/ha，特佳為1〇至 1000 g/ha(當採用洗水法或滴流法施用時’甚至可再降 低施用率’尤其當使用惰性物質時，如：岩棉或珍珠 岩）。為了本發明之目的’此等施用率僅供舉例說明， 並未加以限制。 三氟敏可呈慣用調配物使用，如：溶液、乳液、可 濕化粉劑、水性與油性懸浮液、粉劑、塵粉劑、糊劑、 可溶性粉劑、可溶性粒劑、撒播用粒劑、懸浮/乳液濃 縮物、浸飽活性物質之天然物質與浸飽活性物質之合成 物質、肥料及含在聚合材料中之微包埋物。 此專§周配物係依已知方式製備，例如：混合活性物 33 201138623 質與增量劑，亦即液體溶劑及/或固態載劑，視需要可 使用介面活性劑，亦即乳化劑與/或勻散劑與/或發泡 劑。調配物製法係在施用前或施用期間於合適設備中進 行。 可用為佐劑之物質為彼等適合對組合物本身與/或 其所衍生之製劑（例如：喷灑液、拌種劑）賦與特殊性質， 如：某些技術性質與/或特殊生物性質之物質。典型之 合適佐劑為：增量劑、溶劑與載劑。 合適之增量劑為例如：水、極性與非極性有機化學 液體。例如：芳香系與非芳香系烴類（如：鏈烷烴、烷 基苯、烷基萘、氯苯）、醇類與多元醇(若適當時，亦可 經取代、醚化與/或酯化）、酮類（如：丙酮、環己酮）、 酯類（包括脂肪類與油類）與（聚）醚類、未取代與經取代 之胺類、醯胺類、内醯胺類（如：N-烷基吡咯啶酮）與内 酯類、砜類與亞砜類（如：二甲亞砜）。 當使用水作為增量劑時，亦可使用例如：有機溶劑 作為共溶劑。基本上適用之液態溶劑為：芳香族如：二 甲苯、曱苯或烷基萘類、氯化芳香烴與氯化脂族烴類 如：氯苯、氯化乙烯或二氯曱烷，脂族烴類如：環己烷 或鏈烧烴，例如：石油分顧物、礦物油與植物油，醇類 如：丁醇或甘醇及其醚類與酯類，酮類如：丙酮、曱基 乙基酮、曱棊異丁基酮或環已酮，強極性溶劑如：二曱 亞礙，及水。 根據本發明，載劑意指天然或合成之有機或無機物 34 201138623 其可為固態或液態，且係為了提供更佳施用性而盘 ^性物質混合或組合，特定言之施用於植物或植物植株 或種子。該固態或液態载劑通常為惰性，且應適用於曲 業。 、辰 合適之固態或液態載劑為： 例如銨鹽及天然礦物磨粉，如高嶺土、黏土、滑石、 白堊、石英、美難性白土、g脫土切藻土，^合 物質磨粉，如高分散度㊉石、m土與㈣鹽；適用: 劑之固態載細如為粉碎與分碎天然礦石，如方解石、 ^理石、浮石、海泡石與白雲石，及無機與有機磨粉之 &成顆粒，及有機物質顆粒，如紙、鋸肩、椰子殼、玉 米稳與煙草桿；適用之乳化劑與/或發泡_如為非離 子性與陰離子性乳化劑，如聚氧乙烯脂肪酸s旨、聚氧乙 烯脂肪醇喊(例如烧芳基聚二醇_員）、烧基確酸鹽、燒 基硫酸鹽、芳基磺酸鹽及蛋白f水解產物；合適勾散ς 為非離子性與/或離子性物質，例如來自醇_ρ〇Ε_斑 ·Ρ0Ρ，類、酸與/或pop-poe醋類、烷基-芳基-與/或 Ρ〇Ρ·Ρ〇Ε _貞、職與/或 Ρ〇Ρ·Ρ〇Ε 加合物、;P0E_與/ 或POP-多7L醇衍生物、咖-與/或p〇p_山梨糖醇軒或_ 糖^ σ物、硫酸燒基g旨或硫酸芳基自旨 '續酸烧基醋或碌 &芳基〜’與鱗酸絲®旨或鱗酸芳基自旨，或相應之p0_ 縫加t物。此外，亦可使用合適之寡聚物或聚合物，例 如彼等由乙歸基單體、丙婦酸、E0與/或P0單獨或組 口，例如（聚）醇類或（聚）胺類所衍生之寡聚物或聚合 35 201138623 物。此外亦可使用木質素與其磺酸衍生物、未修飾與經 修飾之纖維素、芳香系與/或脂系磺酸類及其與曱醛之 加合物。 調配物中可使用膠黏劑，如羧曱基纖維素、呈粉 末、顆粒或膠乳型式之天然與合成聚合物，如阿拉伯 膠、聚乙烯醇與聚醋酸乙烯酯，及天然磷脂，如腦磷脂 與卵磷脂，及合成磷脂。 亦可使用著色劑，如無機色素(例如氧化鐵，氧化 鈦與普魯士藍）及有機染料，如茜素染料，偶氮染料及 金屬酞花青染料，及微量營養素，如鐵、猛、棚、銅、 鈷、鉬與鋅之鹽類。 其他可能之添加物為芳香成份、可視需要改質之礦 物油或植物油、鐵類與營養素（包括微量營養素），如鐵、 錳、硼、銅、鈷、鉬與鋅之鹽類。 其他可存在之物質為安定劑，如低溫安定劑、防腐 劑、抗氧化劑、uv安定劑或其他改善化學/物理安定性 之製劑。 由調配物商品製成之施用形式中之三氟敏含量可 在很大範圍内變化。施用形式之活性物質總濃度或個別 活性物質之活性物質濃度可在〇.〇〇〇〇〇〇01至97重量％ 之範圍内，較佳為〇.〇〇〇〇〇〇1至97重量％之範圍内，尤 其佳為0.000001至83重量％之範圍内或0.000001至5 重量％之範圍内，及極尤其佳為0.0001至1重量％之範 圍内。 36 201138623 该等化合物可依適合施用形式之一般方法施用。 中所有植物及植株部份均可依據本發明處理。本文 命，咸瞭解植物係指所有植物及植物族群，如需要及不 、要之野生植物或作物（包括天然作物）。作物可為得自 ^傳統植物育種法與最適化方法或利用生物技術與重 奴法或此等方法之組合所取得者，包括轉殖基因植物， 包括受植物育種者權益保護或未受保護之植物栽培品 ，。亦咸瞭解，植株部份意指植物之所有地上及地下部 分與器官，如芽、葉、花與根，其實例可述及：闊葉、 斜葉、軸、莖、花、果實體、果實與種子，及根、塊莖 蚵根至。植株部份亦包括收穫之材料，與無性及有性繁 歹直材料，例如果實、種子、插扦、塊莖、根莖、腋芽”、 ，子、株芽、壓條及走莖。同樣地，可以處理野生型或 轉由傳統生物育種法(如：雜交或原生質融合法)得到之 植物，及其部份植株。本發明一項變化中，係處理藉由 重組方法，例如：反義或共同抑制技術、RNA干擾_ RNAi -技術，若適當時，組合傳統方法得到之植 因改造生物)及其部份植株。 （基 下列貫例說明本發明，但未限制本申請案。 t實施方式】 ^進仃溫室貫施，以評估施用殺真菌劑對果實品質之 t響，特疋s之二氟敏對蕃茄果頂腐爛病強度之影響。 因此在石棉上，依不同鈣施用法、1〇〇 %及％ %鈣濃 37 201138623 度，施用及不施用三氟敏下，栽種蕃茄植物品種 “Harzfeuer”。 實例 A:試驗蕃茄（Lycopersicon esculentum MILL·)，Harzfeuer 品種 採用滴灌施藥系統，與灌溉法組合施肥。 取蕃蘇escw/e扣wm MILL.)，栽培品種 Harzfeuer播種在岩棉上，約3週後，將植物移至岩棉 袋上。經過指定間隔後，以三氟敏及/或改良式霍格蘭 (Hogland)溶液（其包含1〇〇 %或33%鈣（Ca-霍格蘭溶 液）’其組成說明於下文中）處理植物4次。 三氟敏已透過市售商品Flint® 50WG溶液（濃度 0.025 % [v/v]三氟敏)施加，及利用滴灌系統施加霍格 蘭溶液。 在播種後’依據下列施用法，使用三氟敏與/或Ca-霍格蘭溶液處理59天(處理組1號）、75天（處理組2 號）、89天（處理組3號)及1〇6天（處理組4): 處理組編號 霍格蘭溶液之Ca-含量[。/0] 施加三氟敏 1 100 -- 2 ' 100 + 3 33 - 4 33 +The common name is used according to the International Standards Organization (Intemati〇nal Organization for Standardizati〇n (IS〇)) or the chemical name of the compound (if appropriate, used with the conventional code), and always includes all applicable types. An acid, a salt, an ester or a modified form thereof, such as an isomer such as a stereoisomer and an optical isomer. At least one suitable type and/or modification may be mentioned as an example. When used in accordance with the methods of the present invention, the rate of application of trifluoperin can vary over a wide range depending on the route of administration. The application rate of the compound according to the invention in the treatment of plant plants (for example: leaf parts) is from 0.1 to 10 000 g/ha, preferably from 1 to 1000 g/ha, particularly preferably from 1 to 1000 g/ha (when used When applied by the wash or drip method, the application rate can be reduced even more, especially when using inert substances such as rockwool or perlite. For the purposes of the present invention, the rates of application are for illustrative purposes only and are not limiting. Trifluoro-sensitive can be used in conventional formulations, such as: solutions, emulsions, wettable powders, aqueous and oily suspensions, powders, dust powders, pastes, soluble powders, soluble granules, granules for spreading, suspensions/emulsions a concentrate, a natural substance that saturates the active substance, a synthetic substance that saturates the active substance, a fertilizer, and a micro-embedded material contained in the polymeric material. This special formulation is prepared in a known manner, for example: mixed active 33 201138623 masogen and extender, ie liquid solvent and / or solid carrier, if necessary, can use surfactant, ie emulsifier and / or a dispersing agent and / or a blowing agent. The formulation process is carried out in a suitable apparatus prior to or during application. The substances which can be used as adjuvants are suitable for imparting special properties to the composition itself and/or its derived preparations (for example: spray liquids, seed dressings), such as certain technical properties and/or special biological properties. Substance. Typical suitable adjuvants are: extenders, solvents and carriers. Suitable extenders are, for example, water, polar and non-polar organic chemical liquids. For example: aromatic and non-aromatic hydrocarbons (eg alkanes, alkylbenzenes, alkylnaphthalenes, chlorobenzenes), alcohols and polyols (if appropriate, substituted, etherified and/or esterified) ), ketones (eg acetone, cyclohexanone), esters (including fats and oils) and (poly)ethers, unsubstituted and substituted amines, guanamines, indoleamines (eg : N-alkylpyrrolidone) with lactones, sulfones and sulfoxides (eg dimethyl sulfoxide). When water is used as the extender, for example, an organic solvent can also be used as the cosolvent. Substantially applicable liquid solvents are: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbons such as chlorobenzene, ethylene chloride or dichlorodecane, aliphatic Hydrocarbons such as cyclohexane or chain hydrocarbons, such as: petroleum products, mineral oils and vegetable oils, alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, thiol Ketone, oxime isobutyl ketone or cyclohexanone, strong polar solvents such as: bismuth, and water. According to the invention, the carrier means a natural or synthetic organic or inorganic substance 34 201138623 which may be in a solid or liquid state, and in order to provide better applicability, the liquid substance may be mixed or combined, in particular applied to the plant or plant plant. Or seed. The solid or liquid carrier is generally inert and should be suitable for use in the arts. Suitable solid or liquid carriers are: for example, ammonium salts and natural mineral mills, such as kaolin, clay, talc, chalk, quartz, melamine white earth, g-earthing algae soil, ^ material grinding, such as High dispersion of ten stone, m soil and (four) salt; Applicable: The solid carrier of the agent is such as crushing and crushing natural ore, such as calcite, marble, pumice, sepiolite and dolomite, and inorganic and organic milling & granules, and organic material particles, such as paper, saw shoulders, coconut shell, corn stabilized with tobacco rods; suitable emulsifiers and / or foaming _ such as nonionic and anionic emulsifiers, such as polyoxygen Ethylene fatty acid s, polyoxyethylene fatty alcohol shout (for example, aryl polyglycol _ member), decyl sulphate, sulphate sulphate, aryl sulfonate and protein f hydrolysate; suitable entanglement Nonionic and/or ionic substances, for example from alcohols _ρ〇Ε_斑·Ρ0Ρ, classes, acids and/or pop-poe vinegars, alkyl-aryl- and/or Ρ〇Ρ·Ρ〇Ε _贞, jobs and / or Ρ〇Ρ · Ρ〇Ε adduct,; P0E_ and / or POP - more 7L alcohol derivatives, coffee - and / or p〇p_ sorbitol Xuan Or _ sugar^ σ, sulphate sulphate or sulphate sulphate from the purpose of 'continued acid ketone vinegar or cum aryl aryl aryl aryl aryl aryl aryl aryl aryl aryl aryl aryl aryl 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或Sew and add t. In addition, suitable oligomers or polymers may also be used, for example, from ethylenic monomers, propylene glycol, E0 and/or P0 alone or in groups, such as (poly)alcohols or (poly)amines. Derived oligomer or polymer 35 201138623. Further, lignin and its sulfonic acid derivative, unmodified and modified cellulose, aromatic and/or aliphatic sulfonic acid, and adducts thereof with furfural may also be used. Adhesives such as carboxymethyl cellulose, natural and synthetic polymers in powder, granule or latex form, such as acacia, polyvinyl alcohol and polyvinyl acetate, and natural phospholipids such as cephalin, may be used in the formulation. With lecithin, and synthetic phospholipids. Coloring agents such as inorganic pigments (such as iron oxide, titanium oxide and Prussian blue) and organic dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes, and micronutrients such as iron, fierce, shed, can also be used. Salts of copper, cobalt, molybdenum and zinc. Other possible additives are aromatic components, mineral oils or vegetable oils, irons and nutrients (including micronutrients) that may be modified as needed, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc. Other substances which may be present are stabilizers such as low temperature stabilizers, preservatives, antioxidants, uv stabilizers or other agents which improve chemical/physical stability. The level of trifluoro-sensitization in the form of application made from the formulation of the product can vary widely. The total concentration of the active substance in the application form or the active substance concentration of the individual active substance may be in the range of from 0.1 to 97% by weight, preferably from 0.1 to 97% by weight. Within the range, it is particularly preferably in the range of 0.000001 to 83% by weight or 0.000001 to 5% by weight, and particularly preferably in the range of 0.0001 to 1% by weight. 36 201138623 The compounds can be administered in a general manner suitable for the form of administration. All plants and plant parts can be treated in accordance with the present invention. This article refers to the fact that plants refer to all plants and plant communities, such as wild plants or crops (including natural crops) that are needed and not needed. Crops may be obtained from traditional plant breeding methods and methods of optimization or using biotechnology and heavy slavery or a combination of such methods, including genetically modified plants, including protected or unprotected by plant breeders. Plant cultivation products, It is also known that plant parts mean all above-ground and underground parts and organs of plants, such as buds, leaves, flowers and roots. Examples can be described as: broadleaf, oblique leaves, shafts, stems, flowers, fruit bodies, fruits. With seeds, and roots, tuberous roots to. The plant part also includes the harvested material, and the asexual and sexually sturdy straight materials, such as fruits, seeds, transplants, tubers, rhizomes, axillary buds, seeds, plant buds, beading and walking stems. Similarly, Plants that are wild-type or transferred to traditional biological breeding methods (eg, hybridization or protoplast fusion), and parts thereof. In a variation of the invention, the treatment is by recombinant methods such as antisense or co-suppression Technology, RNA interference _ RNAi - technology, if appropriate, combined with the traditional method to obtain the genetically modified organism) and some of its plants. (The following examples illustrate the invention, but do not limit the application. t embodiment) ^ Into the greenhouse to assess the effect of the application of fungicides on the quality of the fruit, the effect of the special dilute s-difluoro-sensitive on the strength of tomato fruit rot. Therefore, on asbestos, according to different calcium application method, 1〇〇 % and % % Calcium 37 201138623 degrees, planted with tomato plant variety "Harzfeuer" with or without application of trifluoro-sensitive. Example A: Test tomato (Lycopersicon esculentum MILL·), Harzfeuer variety using drip irrigation In combination with the irrigation method, fertilize. Take the escw/e buckle wm MILL.), the cultivar Harzfeuer is planted on rock wool, and after about 3 weeks, the plants are moved to the rock wool bag. After the specified interval, three Fluorine-sensitive and/or modified Hogland solutions (which contain 1% or 33% calcium (Ca-Hawgrain solution) whose composition is described below) are treated 4 times. Application via commercial product Flint® 50WG solution (concentration 0.025% [v/v] trifluoro-sensitive) and application of Hoagland solution using a drip irrigation system. After sowing, use of trifluoro-sensitive and/or Ca according to the following application methods - Hoagland solution treatment for 59 days (treatment group No. 1), 75 days (treatment group No. 2), 89 days (treatment group No. 3) and 1〇6 days (treatment group 4): treatment group number Hoagland solution Ca-content [./0] applied with trifluoro-sensitive 1 100 -- 2 ' 100 + 3 33 - 4 33 +

Ca-霍格蘭溶液: 鹽 100 % Ca-霍格蘭溶液[mg/l] 33 % Ca-霍格蘭溶液 [mg/1] MnCh X H2O 0,502 Μη 0,502 Μη KH2PO4 39.1 Κ 39.1 Κ ZnS〇4 x 7 H2O 0.1 Ζη 0.1 Ζη Na2B4〇7 0.49 Β 0.49 Β 38 201138623Ca-Hawthorne solution: salt 100% Ca-Hawgrain solution [mg/l] 33% Ca-Holland solution [mg/1] MnCh X H2O 0,502 Μη 0,502 Μη KH2PO4 39.1 Κ 39.1 Κ ZnS〇4 x 7 H2O 0.1 Ζη 0.1 Ζη Na2B4〇7 0.49 Β 0.49 Β 38 201138623

CuS〇4 X 7 H2O 0.02 Cu 0.02 Cu —~ Na2Mo04 x 2 H20 0.024 Mo 0.024 Mo MgS04 x 7 H20 48.6 Mg 48.6 Mg Ca(N03)2 x 4 H20 200.5 Ca /140 N 66.8 Ca/46.7N NH4NO3 58.3 N KNO3 195.5 K/70 N 293.3 K/105 N ~ FetrilonIM 13 %，一種含水 溶性鐵之肥料 5.2 Fe 5.2 Fe 針對綠色或紅色果實分析果頂腐爛病病癥之頻率 及強度。分析法係於三個不同生長階段進行，其中最後 一個及最終分析係由總狀花序成熟度決定。 (a)三氟敏對綠色果實果頂腐爛病頻率之影響 已發現在完全鈣供應量（100 %)下栽培之蕃茄植物 之綠色果實在播種後99天（第一階段分析）及112天（第 2階段分析）時，沒有出現與果頂腐爛病相關之病癥。 甚至在第三階段(最終)分析時，完全鈣肥及施加三 氣敏之組合即可以防止果頂腐爛病之發生，而未處理之 蕃茄病瘢則肉眼可見。在營養缺乏下生長之果實，未處 理之蕃力α出現果頂腐爛病病薇之頻率高於三氟敏處理 組蕃茄。然而，未處理組與三氟敏處理組蕃茄之間出現 果頂腐爛病之頻率差異會隨時間延長而下降。在缺乏 Ca下栽培之蕃茄出現果頂腐爛病之頻率高於在1〇〇 % Ca下生長之果實。 處理組 沒有果頂腐爛病之綠色蕃茄果實 第-p皆段分析第二階段分析第三階段分析CuS〇4 X 7 H2O 0.02 Cu 0.02 Cu —~ Na2Mo04 x 2 H20 0.024 Mo 0.024 Mo MgS04 x 7 H20 48.6 Mg 48.6 Mg Ca(N03)2 x 4 H20 200.5 Ca /140 N 66.8 Ca/46.7N NH4NO3 58.3 N KNO3 195.5 K/70 N 293.3 K/105 N ~ FetrilonIM 13 %, a fertilizer containing water-soluble iron 5.2 Fe 5.2 Fe The frequency and intensity of the fruit rot disease is analyzed for green or red fruits. The analytical method is performed at three different growth stages, with the last and final analysis being determined by the maturity of the racemes. (a) Effect of trifluoro-sensitive on the frequency of fruit rot in green fruits It has been found that the green fruits of tomato plants cultivated under complete calcium supply (100%) are 99 days after sowing (first stage analysis) and 112 days ( At the second stage of analysis, there were no symptoms associated with rot of the fruit. Even in the third (final) analysis, the combination of complete calcium and application of three gas sensitivities prevented the occurrence of fruit rot, while the untreated tomato sputum was visible to the naked eye. In the fruit that is grown under nutrient deficiencies, the untreated arsenic α has a higher frequency of fruit rot disease than the fluoride-treated tomato. However, the frequency difference between the untreated group and the tomato in the trifluorosensitive treatment group decreased with time. Tomatoes grown in the absence of Ca have a higher frequency of fruit rot than fruits grown at 1% Ca. Treatment group Green tomato fruit without fruit rot disease Phase I analysis of the second phase of the second phase analysis

39 201138623 UTC* (33 % Ca) 229 78 317 80 105 72 三氟敏(100 % Ca) 377 100 447 100 158 100 三氟敏(33 % Ca) 290 88 360 83 128 74 *UTC=未處理之對照組（未施加三氟敏) (b)三氟敏對紅色果實果頂腐爛病頻率之影響 在完全鈣供應量下，紅色蕃茄果實在播種112天 後，不論未施加殺真菌劑組或三氣敏處理組，均未記錄 到果頂腐爛病病癥。在辦缺乏下生長時，未施加殺真菌 劑組有許多紅色蕃茄果實出現果頂腐爛病。在此等情況 下施加三氟敏，可以顯著降低與果頂腐爛病相關病癥之 出現頻率。 沒有果顶腐爛病之紅色蕃茄果實 處理組 第一階段分析 [η] [%] 第二階段分析 Μ [%] 第三階段分析 [η] [%] UTC*(100%Ca) - - 65 100 417 98 UTC* (33 % Ca) 5 19 25 24 198 40 三氟敏(100 % Ca) - 50 100 448 99 三氟敏(33 % Ca) 11 52 34 39 224 46 *UTC=未處理之對照組（未施加三氟敏) (c)三氟敏對在缺乏Ca下生長之紅色果實上果頂腐 爛病強度之影響 相較於未處理對照組(UTC)，施加三氟敏可以降低 201138623 在缺乏Ca下生長之蕃茄果實上果頂腐爛病病癥強度。 在第一階段及第二階段分析中，未處理組植物之果頂腐 爛病病癥之主要特徵為中度至嚴重病癥。三氟敏處理組 植物之蕃茄果實主要出現無或輕度病癥，尤其在第二階 段及第三階段(最終)分析時。 第一階段分析： 處理組 無或輕度病癥 中度至嚴重病癒 Μ [%] [η] [%] UTC (33 % Ca) 10 38 16 62 三氟敏(33 % Ca) 12 57 9 43 第二階段分析: 處理組 無或輕度病癥 中度至嚴重病-癥 Μ [%] [η] [%] UTC (33 % Ca) 44 42 61 58 三氟敏(33 % Ca) 60 69 27 31 第三階段分析: 處理組 無或輕度病癥 中度至嚴重病瘤： Μ [%] W [%] UTC (33 % Ca) 319 65 172 35 三氟敏(33 % Ca) 365 74 126 26 41 201138623 【圖式簡單說明】 無 【主要元件符號說明】 無 4239 201138623 UTC* (33 % Ca) 229 78 317 80 105 72 Trifluoro-sensitive (100 % Ca) 377 100 447 100 158 100 Trifluoro-sensitive (33 % Ca) 290 88 360 83 128 74 *UTC=untreated control Group (no application of trifluoro-sensitive) (b) Effect of trifluoro-sensitive on the frequency of fruit rot in red fruits At full calcium supply, red tomato fruit was seeded for 112 days, no fungicide group or trigas In the sensitive treatment group, no fruit rot disease was recorded. In the absence of growth, there were many red tomato fruits in the group where no fungicide was applied. The application of trifluoro-sensitive in these conditions can significantly reduce the frequency of occurrence of conditions associated with rot disease. First stage analysis of red tomato fruit treatment group without fruit rot disease [η] [%] Second stage analysis Μ [%] Third stage analysis [η] [%] UTC*(100%Ca) - - 65 100 417 98 UTC* (33 % Ca) 5 19 25 24 198 40 Trifluoro-sensitive (100 % Ca) - 50 100 448 99 Trifluoro-sensitive (33 % Ca) 11 52 34 39 224 46 *UTC=untreated control (No application of trifluoro-sensitive) (c) Effect of trifluoro-sensitive on the intensity of fruit rot in red fruits grown in the absence of Ca compared to the untreated control (UTC), the application of trifluoro-sensitive can be reduced in 201138623 The strength of the fruit rot disease on the tomato fruit grown under Ca. In the first and second phase analyses, the main feature of the apical disease of the untreated group of plants was a moderate to severe condition. The trifluoro-sensitive treatment group mainly showed no or mild disease in the tomato fruit of the plant, especially in the second and third stage (final) analysis. Phase I analysis: No or mild symptoms in the treatment group were moderate to severely ill [%] [η] [%] UTC (33 % Ca) 10 38 16 62 Trifluoro-sensitive (33 % Ca) 12 57 9 43 Phase II analysis: Treatment group no or mild condition Moderate to severe disease-symptoms [%] [η] [%] UTC (33 % Ca) 44 42 61 58 Trifluoro-sensitive (33 % Ca) 60 69 27 31 Stage 3 analysis: Treatment group with no or mild symptoms Moderate to severe disease: Μ [%] W [%] UTC (33 % Ca) 319 65 172 35 Trifluoro-sensitive (33 % Ca) 365 74 126 26 41 201138623 [Simple description of the diagram] No [Main component symbol description] No 42

Claims (1)

201138623 七、申請專利範圍： 1. 一種以三氟敏(Trifloxystrobin)於降低園藝作物果 頂腐爛病頻率及/或強度上之用途。 2. 根據申請專利範圍第1項之用途，其中採用喷灑 施用法施加三氟敏。 3. 根據申請專利範圍第1或2項之用途，其中三氟 敏之濃度為0.0001至1重量％之範圍内。 4. 根據申請專利範圍第1至3項中任一項之用途， 其中該園藝作物係選自：胡蘿蔔、南瓜(pumpkin、 squash)、櫛瓜、馬鈐薯、甜玉米、洋蔥、觀賞植 物、藥草、食用草本植物、蕃祐、疲菜、胡椒、 甜瓜、萵苣、小黃瓜、芹菜、甜菜、捲心菜、花 菜、球芽甘藍、球莖甘藍、羽衣甘藍、蘿蔔、大 頭菜、蕪菁、蘆筍、豆類、豌豆、蘋果、覆盆子、 草莓、香蕉、芒果、葡萄、桃、梨、番石榴、鳳 梨、石權、大蒜、辣椒(capsicum、chilli)、蘿蔔、 揚桃、木薯、胡桃、檸檬、橘子、檬果(mangold)、 香菇、橄欖、柳橙、木瓜、甜椒、百香果、花生、 核桃、梅子、開心果、柿、葡萄柚(pamplemouse)、 茄子、菊苣、蔓越莓、醋栗、榛果、奇異果、杏 43 201138623 仁、莧菜、杏桃、朝鮮薊、駱梨、黑莓、腰果、 櫻桃、柑橘、椰子與洋香瓜。 5. 根據申請專利範圍第1至4項中任一項之用途， 其中該園藝作物為傳統作物或基因改造作物。 6. 根據申請專利範圍第1至5項中任一項之用途， 其中三氟敏係與至少一種選自下列各物所組成群 中之其他活性化合物組合使用：殺昆蟲劑、引誘 劑、消毒劑、殺菌劑、殺蜱蜗劑、殺線蟲劑、殺 真菌劑、調節生長物質、除草劑、保護劑（safener)、 肥料、化學信息物質及生物防治劑。 7. 一種降低園藝作物果頂腐爛病頻率及/或強度之方 法，其包括施加三氟敏之步驟。 44 201138623 四、 指定代表圖： (一） 本案指定代表圖為：無 (二） 本代表圖之元件符號簡單說明： 無 五、 本案若有化學式時，請揭示最能顯示發明特徵的化學式：201138623 VII. Patent application scope: 1. A use of Trifloxystrobin to reduce the frequency and/or intensity of horticultural crop rot. 2. According to the use of the first application of the scope of patent application, the use of spray application of the application of trifluoro-sensitive. 3. The use according to claim 1 or 2, wherein the concentration of the trifluorosensitive agent is in the range of 0.0001 to 1% by weight. 4. The use according to any one of claims 1 to 3, wherein the horticultural crop is selected from the group consisting of: carrots, pumpkins, squash, melons, horses, sweet potatoes, onions, ornamental plants, Herb, edible herb, fan, tired, pepper, melon, lettuce, cucumber, celery, beet, cabbage, cauliflower, Brussels sprouts, broccoli, kale, radish, kohlrabi, turnip, asparagus, beans, peas , apple, raspberry, strawberry, banana, mango, grape, peach, pear, guava, pineapple, stone, garlic, capsicum (capsicum, chilli), radish, yam, cassava, walnut, lemon, orange, lemon (mangold), mushrooms, olives, oranges, papayas, sweet peppers, passion fruit, peanuts, walnuts, prunes, pistachios, persimmons, grapefruit (pamplemouse), eggplant, chicory, cranberry, gooseberry, hazelnut, Kiwi, apricot 43 201138623 Kernel, amaranth, apricot, artichoke, pineapple, blackberry, cashew, cherry, citrus, coconut and cantaloupe. 5. The use according to any one of claims 1 to 4, wherein the horticultural crop is a traditional crop or a genetically modified crop. 6. The use according to any one of claims 1 to 5, wherein the trifluoro-sensitive system is used in combination with at least one other active compound selected from the group consisting of insecticides, attractants, disinfectants Agents, fungicides, mites, nematicides, fungicides, growth regulating substances, herbicides, safeners, fertilizers, chemical information substances and biological control agents. 7. A method of reducing the frequency and/or intensity of fruit rot of a horticultural crop comprising the step of applying a trifluoron. 44 201138623 IV. Designated representative map: (1) The representative representative of the case is: None (2) The symbol of the symbol of the representative figure is simple: None 5. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention: 22
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