201132339 六、發明說明： 【發明所屬之技術領域】 特別是指一種洗腎用人工 本發明是有關於一種血管 血管。 【先前技術】 洗腎病人於進行洗腎前，通常得要先進行屢管之建置 ，而所用之屢管通常是由動、靜脈相接製成之動靜脈屢管 ，可避免發生病患本身之免疫反應，但這種動靜脈摩管使 用時，在經過一段時間之後，通常會逐漸阻塞而無法再使 用，且拔針後的止血步驟也會相當麻煩，再加上萬一病串 止血不當或保養不當，也會縮短動靜脈屢管之使用壽命。 —有鑑於此，目前市面上已有可用以替代前述動靜脈屢 &之人工血管’但因為此種人工血管主要是由高分子材料 製成，所以其於穿刺針拔離後，仍需要進行加壓止血步驟 ，且於加壓止血過程中，也容易因為加壓不當而發生阻塞 現象。 【發明内容】 因此，本發明之目的，即在提供一種有助於生物組織 增生附著且方便使用之洗腎用人工血管。 於是，本發明洗腎用人工血管，適用於供洗腎用針體 穿刺，包含一彈性的密合層，及二相向包覆於該密合層外 之管狀的包覆層。該密合層是由具自動密合封口特性之生 物相容性材料製成，可於所述針體穿刺拔離後自動密合封 口。該等包覆層是由多孔性生物相容性材料製成，且分別 201132339 沿該密合層長度方向延伸地分別被覆固定於該密合層内、 外側面，而相配合形成一用以供血液通過之輸血管路。 本發明之功效：透過於包覆層間設置該密合層的結構 設計’使得本發明洗腎用人工血管可於穿刺針拔離後，立 即密合封口 ’而可在不需加壓情況下立即止血，所以可避 免因加壓不當所引起的阻塞現象，相對提高洗腎用人工血 管之安全性。 【實施方式】 有關本發明之别述及其他技術内容、特點與功效，在 以下配合參考圖式之一個較佳實施例的詳細說明中，將可 清楚的呈現。 參閱圖1〜4，本發明洗腎用人工血管之較佳實施例，適 用於植入人體中，而用以連通固接於—動_ 9Q1與一靜脈 9〇2間，用以做為洗腎用屢管，可供洗腎用之針體_穿刺 長片狀之彈性的密合層31 内、外側面且相接合之中 該洗腎用人工血管3包含一 ，及分別包覆固定於該密合層Η 空管狀包覆.層32。 該密合層31是士目 材㈣A a 密合封口特性之生物相容相 材料製成，於所述斜轉8λλ w m 穿刺拔離後，針體_所造治 之開口會自動密合封閉， 速止血之目的。在本—T立即防止血液外漏，達到# Γ Ί. , . j 貫施例中，該密合層31是由矽脒材t (silicon)製成，作膏 疋田/胗材参 貫施時不以此為限。 該等包覆層32县八 刀別沿該密合層31長度方向延伸， 201132339 而相配合形成一用以供血液通過之輸血管路3〇，每一包覆 層32具有一貼抵固定於該密合層31内、 | 甲一側面之 長片狀包覆部321、-與該包覆部321間隔相向並另一包覆 層32相向疊接固定之長片狀接合部322，及二分別往外延 伸出該密合層31兩相反端且分別與另—包覆層32相向貼 抵固接之管狀縫合部323。201132339 VI. Description of the invention: [Technical field to which the invention pertains] In particular, it relates to a manual for dialysis. The present invention relates to a blood vessel. [Prior Art] Before dialysis, patients with dialysis usually have to carry out repeated management. The commonly used tubes are usually connected by arteries and veins made of arteries and veins to avoid the occurrence of patients. The immune response itself, but when used in this arteriovenous tube, after a period of time, it usually blocks and can no longer be used, and the hemostasis step after the needle is quite troublesome, plus the blood stasis in case of disease Improper or improper maintenance will also shorten the service life of arteriovenous tubes. - In view of this, there are currently available artificial blood vessels in the market to replace the above-mentioned arteriovenous and amp; but because the artificial blood vessels are mainly made of polymer materials, they still need to be carried out after the needle is pulled out. The pressure hemostasis step, and during the pressurization and hemostasis, is also likely to cause occlusion due to improper pressurization. SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide an artificial blood vessel for dialysis that contributes to the proliferative attachment of biological tissues and is convenient to use. Accordingly, the artificial blood vessel for dialysis of the present invention is suitable for puncture of a needle for washing kidneys, and comprises an elastic adhesive layer and a tubular coating layer which is coated in two opposite directions to the outside of the adhesive layer. The adhesive layer is made of a biocompatible material having a self-sealing sealing property, and can be automatically closed to the seal after the needle is punctured. The coating layers are made of a porous biocompatible material, and respectively, 201132339 is respectively extended and fixed along the length of the adhesive layer to be fixed in the inner and outer sides of the adhesive layer, and cooperate to form one for The blood passes through the blood vessel. The effect of the invention is that the structural design of the adhesive layer is provided between the coating layers, so that the artificial blood vessel for dialysis of the invention can be tightly closed after the needle is pulled out, and can be immediately pressed without pressure. Hemostasis, so it can avoid the obstruction caused by improper pressurization, and relatively improve the safety of artificial blood vessels for dialysis. DETAILED DESCRIPTION OF THE INVENTION The detailed description of the preferred embodiments of the present invention will be apparent from Referring to Figures 1 to 4, a preferred embodiment of the artificial blood vessel for dialysis of the present invention is suitable for implantation in a human body, and is used for communication and fixation between the _ 9Q1 and a vein 9 〇 2 for washing. Kidney-receiving tube, needle for dialysis _ puncture of the elastic sheet of the elastic sheet 31, the inner and outer sides of the dialysis, including the vascular prosthesis 3, and the coating and fixing The adhesion layer is hollow tubular coated with layer 32. The adhesive layer 31 is made of a biocompatible phase material with a sealing property of the material (4) A a. After the oblique 8λλ wm is puncture and pulled away, the opening of the needle body is automatically closed and closed. The purpose of stopping bleeding. In this case, the T-T is immediately prevented from leaking out of the blood, reaching # Γ Ί. , . j. In the example, the adhesion layer 31 is made of coffin t (silicon), which is used as a paste field/coffin. Not limited to this. The covering layers 32 and the eight knives extend along the length of the adhesive layer 31, and 201132339 cooperate to form a blood vessel path 3 for blood to pass through, and each of the covering layers 32 has a fixing and fixing In the adhesive layer 31, a long sheet-like covering portion 321 on one side of the nail, a long sheet-like joint portion 322 which is spaced apart from the covering portion 321 and which is oppositely fixed to the other covering layer 32, and two The tubular suture portions 323 which are oppositely extended from the opposite ends of the adhesion layer 31 and which are respectively opposed to the other cladding layer 32 are attached.
邊等包覆層32是由多孔性之生物相容性材料製成，但 其孔隙小到無法使血液往外滲出，且此多孔性特性，可供 生物組織增生攀附於外層包覆層32之外表面，進而使得該 洗腎用人工血管3被攀附之生物組織牢牢抓住，而定位於 體表下之植入部位。 在本實施例中，製造包覆層32之材料是選自於由聚酯 類高分子（polyester )、四氟化聚乙烯（ polytetrafluorothylene . PTEF )、聚胺基甲酸醋（ polyurethane，PU)，以及聚酯類高分子、四氟化聚乙烯與 聚胺基曱酸醋之混合所組成之群體。其中，該聚酯類高分 子是選自於由聚酯纖維（p〇lyester fiber，達克隆（Dacron))、 聚乳酸（polylactic acid，PLA )、聚甘醇酸（polygiyc〇lic acid，PGA )，以及聚 @旨纖維（p〇iyester fiber )、聚乳酸（ polylactic acid ’ PLA )與聚甘醇酸（p〇iygiyC〇He acid， PGA)之混合所構成之共聚物。 本發明洗腎用人工血管3植入病患900體表下使用時 ’該密合層31必須朝向病患900體表側，而使該等包覆層 32之接合部322靠向肌肉側，然後將該等包覆層32相接合 201132339 之該等縫合部323分別縫接套置於動脈9〇1與靜脈9〇2外 ，使本發明洗腎用人通血管3連通於動脈9〇1與靜脈9〇2 間，而可用以輸送血液。並利用該包覆層32之多孔性材質 特性，使其植入體表後，人體組織能夠逐漸增生附著，進 而使該洗腎用人工血管3定位而不易滑動，方便進行插針 輸血。 當該洗腎用人工血管3已被附著之生物組織大致抓住 疋位後，便可用以進行洗腎作業，因該密合層31之可自動 密合的材料特性，所以當穿刺之針體8〇〇拔離後，該密合 層31被穿刺形成之小開口便會自動夾靠密合，而立刻自動 止血，相當方便，且因該密合層31是呈長片狀，所以可供 多次穿刺。 當該洗腎用人工血管3 一但被人體組織攀附抓住定位 後，僅朝向體表之一側的部位會被插針，所以本實施例洗 腎用人工血官3之密合層31是採用長片狀結構設計專門 用以做為被插針部位使用，而鄰近肌肉部位則未設置密合 層31 ’以節省材料。但實施時，該密合層31也可改用管狀 ’‘構°又3十’而將該等包覆層32分別貼抵固定於該管狀密合 層31之内外周面，而構成三層管狀結構之洗腎用人工血 管3。 歸’内上述透過於具自動密合封口特性之密合層31内 、外側面分別包覆固定一層由多孔性生物相容性材料製成 之包覆層32的設計，使得本發明洗腎用人卫血管3植入體 表下後’能夠被人體組織攀附抓住而定位，所以較不易發 201132339 生滑移現象，可改善插針作業之方便性，並可利用包覆層 32間之密合層31可於針體咖拔離後立即密合封口的特性 ’達到免按Μ止血且止血快速的目的，也可完全避免習知 人工血管會因域不當而產生阻塞的情況，所以也可相對 提高本發明洗腎用人工血管3之安全性。因此，確實可達 到本發明之目的。 惟以上所述者，僅為本發明之較佳實施例而已，當不 能以此限定本發明實施之範圍，即大凡依本發明申請專利 範圍及發明說明内容所作之簡單的等效變化與修飾，皆仍 層本發明專利涵蓋之範圍内。 【圖式簡單說明】 圖1是本發明洗腎用人工血管之一較佳實施例的立體 示意圖； 圖2是該較佳實施例的斷面剖視圖； 圖3是該較佳實施例之側視剖面圖；及 圖4是該較佳實施例植入體表下而連通於動脈與靜脈 間的示意圖。 201132339 【主要元件符號說明】 3....... ....洗腎用人工血管 323..·. ____縫合部 30 ..... .…輸血管路 800.··· ....針體 31 …·· ....密合層 900.·.· ....病患 32 …·. ....包覆層 901.... —動脈 321.... ....包覆部 902.... ....靜脈 322.... ....接合部The edge-like cladding layer 32 is made of a porous biocompatible material, but its pores are so small that it does not allow blood to ooze out, and this porous property allows the biological tissue to proliferate and adhere to the outer cladding layer 32. The surface, in turn, causes the lavat artificial blood vessel 3 to be firmly grasped by the adherent biological tissue, and is positioned at the implantation site under the body surface. In this embodiment, the material for manufacturing the cladding layer 32 is selected from the group consisting of polyester, polytetrafluorothylene (PTEF), polyurethane, and A group consisting of a polyester polymer, a mixture of tetrafluoroethylene and polyamine phthalic acid vinegar. Wherein, the polyester polymer is selected from the group consisting of polyester fibers (Dacron), polylactic acid (PLA), and polygiyc〇lic acid (PGA). And a copolymer composed of a mixture of p〇iyester fiber, polylactic acid 'PLA, and polyglycolic acid (PGA). When the dialysis artificial blood vessel 3 is implanted under the surface of the patient 900, the adhesive layer 31 must face the body side of the patient 900, and the joint portion 322 of the coating layer 32 is leaned toward the muscle side, and then The suture portions 323 of the coating layer 32 joined to 201132339 are respectively sewn and placed outside the artery 9〇1 and the vein 9〇2, so that the dialysis diarrhea of the present invention is connected to the artery 9〇1 and the vein. 9〇2, which can be used to deliver blood. By utilizing the porous material property of the coating layer 32, the human tissue can be gradually accumulating and adhering after being implanted into the body surface, thereby allowing the dialysis to be positioned by the artificial blood vessel 3 without being easily slid, thereby facilitating needle transfusion. When the biological tissue to which the dialysis artificial blood vessel 3 has been attached is substantially grasped, the dialysis operation can be performed. Because of the material property of the adhesive layer 31 which can be automatically adhered, when the needle body is puncture After the 8〇〇 is pulled out, the small opening formed by the puncture layer 31 is automatically clamped and tightly closed, and the blood is automatically stopped immediately, which is quite convenient, and since the adhesive layer 31 is in the form of a long piece, it is available. Multiple punctures. When the artificial blood vessel 3 for dialysis is grasped and positioned by the human body tissue, only the portion facing the side of the body surface is inserted, so the adhesive layer 31 of the artificial blood donor 3 for dialysis in this embodiment is The long sheet structure is designed to be used as a pinned portion, and the adjacent muscle portion is not provided with an adhesive layer 31' to save material. However, in the implementation, the adhesive layer 31 can also be replaced with a tubular shape of 30 Å and the cladding layers 32 are respectively fixed to the inner and outer peripheral surfaces of the tubular adhesive layer 31 to form a three-layer layer. An artificial blood vessel for dialysis of a tubular structure. The design of the coating layer 32 made of a porous biocompatible material is respectively covered in the inner and outer sides of the adhesive layer 31 having the characteristics of automatic sealing and sealing, so that the dialysis person of the present invention is used. After the vascular tube 3 is implanted under the surface of the body, it can be positioned by the body tissue, so it is not easy to send the 201132339 slip phenomenon, which can improve the convenience of the needle operation and can be used to close the gap between the coating layers 32. The layer 31 can close the sealing property immediately after the needle body is pulled out to achieve the purpose of avoiding blood stasis and stopping bleeding quickly, and completely avoiding the situation that the artificial blood vessel may be blocked due to improper field, so it can also be relatively The safety of the artificial blood vessel 3 for dialysis of the present invention is improved. Therefore, it is indeed possible to achieve the object of the present invention. The above is only the preferred embodiment of the present invention, and the scope of the invention is not limited thereto, that is, the simple equivalent changes and modifications made by the scope of the invention and the description of the invention are All are still within the scope of the invention patent. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a perspective view of a preferred embodiment of an artificial blood vessel for dialysis according to the present invention; FIG. 2 is a cross-sectional view of the preferred embodiment; FIG. 3 is a side view of the preferred embodiment. A cross-sectional view; and Figure 4 is a schematic illustration of the implant of the preferred embodiment of the implant between the artery and the vein. 201132339 [Description of main component symbols] 3......... Artificial blood vessel for dialysis 323..·. ____Sewage part 30 ..... .... Transfusion channel 800.··· . ... needle body 31 ...·· .... close layer 900.·.. .... patient 32 ..... ... coating layer 901.... - artery 321.... .... cladding portion 902..... vein 322..... joint