201120026 六、發明說明 【發明所屬之技術領域】 本發明係關於一種稻益科（£> e /;? /ι a c / C? a e )昆蟲防制組成 物及一種稻蝨科昆蟲防制方法。 【先前技術】 迄今已知對稻蝨科昆蟲具有防制效果之菸鹼乙醯膽鹼 受體激動劑（參見，例如，JP-A 3-157308、JP-A 2001-072678及農業與食品化學雜誌（journai 〇f Agricultural and Food Chemistry) ， 1994 ， 42 ，第 2917-2921 頁）° 然 而’仍有需要對稻蝨科昆蟲具有較高防制效果之防制劑。 【發明內容】 發明總論 本發明的一目的爲提供一種對稻蟲科昆蟲具有極佳防 制效果之稻蝨科昆蟲防制組成物及一種稻蝨科昆蟲防制方 法。 本發明之發明人深入硏究且結果發現：藉由使用至少 一種選自由可尼丁（clothianidin)、益達胺（imidacloprid)及 賽速安（thiamethoxam)所組成群組之菸鹼乙醯膽鹼受體激 動劑倂用N-(2-乙基己基）-5-降莰烯-2,3-二甲醯亞胺改良 防稻蝨科昆蟲之防制活性。因此完成本發明。 本發明提供： [1 ]—種稻蝨科昆蟲防制組成物，其包含至少一種選 -5- 201120026 自由可尼丁（〇丨〇111丨311丨(1丨11)、益達胺（丨111丨(13(：1(^1^)及賽速安 (thiamethoxam)所組成群組之菸鹼乙醯膽鹼受體激動劑和 1^-(2-乙基己基）-5_降莰烯-2,3-二甲醯亞胺作爲活性成分； [2] 根據[1 ]之稻蝨科昆蟲防制組成物，其中菸鹼乙 醯膽鹼受體激動劑對N-(2-乙基己基）-5-降莰烯-2,3-二甲 醯亞胺的重量比以菸鹼乙醯膽鹼受體激動劑/N-(2-乙基己 基）-5-降莰烯-2,3-二甲醯亞胺表示係在1/0.1至1/10,000 之範圍內； [3] —種稻蝨科昆蟲防制方法，其包含將有效量的至 少一種選自由可尼丁、益達胺及賽速安所組成群組之菸鹼 乙醯膽鹼受體激動劑及N-(2-乙基己基）-5-降莰烯-2,3-二 甲醯亞胺施用至稻蝨科昆蟲或稻蝨科昆蟲的棲息地； [4] 根據[3]之稻蝨科昆蟲防制方法，其中該稻蝨科 昆蟲爲褐飛虱（Nilaparvata lugens); [5] 根據[3]之稻蝨科昆蟲防制方法，其中該稻蝨科 昆蟲的棲息地爲稻田。 [6] —種稻蝨科昆蟲防制方法，其包含將有效量的至 少一種選自由可尼丁、益達胺及賽速安所組成群組之菸鹼 乙醯膽鹼受體激動劑及Ν·(2-乙基己基）-5-降莰烯-2,3-二 甲醯亞胺以淹沒方式施用至稻田； [7] —種稻蝨科昆蟲防制方法，其包含將有效量的包 含至少一種選自由可尼丁、益達胺及賽速安所組成群組之 菸鹼乙醯膽鹼受體激動劑及N-(2-乙基己基）-5-降莰烯-2，3-二甲醯亞胺的顆粒或液體組成物以淹沒方式施用至稻 -6 - 201120026 田；及 [8] —種至少一種選自由可尼丁、益達胺及賽速安所 組成群組之菸鹼乙醯膽鹼受體激動劑及N-(2-乙基己基）-5-降莰烯-2,3-二甲醯亞胺於防制稻蝨科昆蟲之用途。 根據本發明之稻蝨科昆蟲防制組成物發揮防稻蝨科昆 蟲的極佳防制效果。 發明之詳細說明 本發明之稻蝨科昆蟲防制組成物包含至少一種選自由 可尼丁（在下文中，有時也稱爲“化合物（1)”）、益達胺（在 下文中，有時也稱爲“化合物（2)”）及賽速安（在下文中，有 時也稱爲“化合物（3 )”）所組成群組之菸鹼乙醯膽鹼受體激 動劑（在下文中，有時也稱爲”化合物I")和N - (2 -乙基己 基）-5-降莰烯-2,3-二甲醯亞胺（在下文中，有時也稱爲”化 合物Π")作爲活性成分。 可尼丁可（例如）根據JP-A 3-157308中所述之方法製 備。 益達胺可（例如）根據JP-A 61-267575中所述之方法製 備。 賽速安可（例如）根據JP-A 6-183918中所述之方法製 備。 N-(2 -乙基己基）-5 -降莰烯-2,3 -二甲醯亞胺爲—種稱爲 MGK264之化合物。N-(2 -乙基己基）-5 -降茨稀- 2,3-二甲醯 亞胺通常用作一種除蟲菊酯化學藥品或有機磷化學藥品之 201120026 增效劑。 在本發明之稻蝨科昆蟲防制組成物中，化合 合物Π(化合物1/化合物II)的重量比通常爲 1 /1 00,000，較佳爲 1/0.1至1 / 1 0,000，然而化合 合物Π的重量比不特別地限制，只要不損失組 佳防制效果即可。 本發明之稻蝨科昆蟲防制組成物可簡單爲化 化合物Π的混合物。本發明之稻蝨科昆蟲防制 常可藉由混合化合物I、化合物II及惰性載體， 加界面活性劑及其他助劑而調配成可乳化濃縮物 濃縮物、可濕性粉劑、水分散性粒劑、水溶性粉 性粒劑、懸浮濃縮物諸如水性懸浮液或水性乳液 粒劑、氣溶膠（aerosol)、油性溶液、微膠囊或 物。 惰性載體包括固體載體、液體載體及氣體載 固體載體的例子包括天然或合成礦物質，諸 高嶺土、滑石、膨潤土、絹雲母、石英、硫、活 酸鈣、矽藻土、浮石、方解石、海泡石、白雲石 氧化鋁、蛭石及珍珠岩；細顆粒諸如鋸屑、玉米 子殼及煙草莖；明膠、凡士林及石蠟油、甲基纖 毛脂及豬油。 液體載體的例子包括芳族或脂族烴類諸如二 苯、烷基萘、苯基二甲苯基乙烷、煤油、輕油、 己烷及液體石蠟；鹵化烴類諸如氯苯、二氯乙烷 物I對化 1/0.01 至 物I對化 成物的極 合物I及 組成物通 及隨意添 、可溶性 劑、水溶 、粉劑、 片狀調配 如黏土、 性碳、碳 、砂石、 穗軸、椰 維素、羊 甲苯、甲 己烷、環 、二氯甲 -8- 201120026 烷及三氯乙烷；醇類諸如甲醇、乙醇、異丙醇、丁醇、己 醇、苯甲醇及乙二醇；醚類諸如二乙醚、乙二醇二甲醚、 二乙二醇單甲醚、二乙二醇單乙醚、丙二醇單甲醚、四氫 呋喃及1，4-二噁烷；酯類諸如乙酸乙酯及乙酸丁酯；酮類 諸如丙酮、甲基乙基酮、甲基乙基酮、甲基異丁酮、及環 己酮；腈類諸如乙腈及異丁腈；碳酸伸烷酯類諸如碳酸伸 丙酯；亞颯類諸如二甲亞颯；醯胺類諸如Ν,Ν-二甲基甲 醯胺及Ν，Ν-二甲基乙醯胺；吡咯啶酮類諸如Ν-甲基-2-吡 咯啶酮、Ν-乙基-2-吡咯啶酮及Ν-辛基-2-吡咯啶酮；咪唑 啶類諸如1，3-二甲基-2-咪唑啶：植物油諸如大豆油或棉 籽油；植物精油諸如橙油、牛膝草油及檸檬油；及水。 氣體載體的例子包括丙烷氣、丁烷氣、液化石油氣、 二甲醚及二氧化碳氣。 界面活性劑的例子包括硫酸烷酯類、磺酸烷酯類、磺 酸烷基芳酯類、烷基芳基醚類及其聚氧乙烯化合物、聚乙 二醇醚類、聚乙二醇脂肪酸酯類、多元醇酯類、糖醇衍生 物、及聚矽氧烷界面活性劑。 用於調配之其他助劑的例子包括酪蛋白、明膠、醣類 (例如澱粉 '阿拉伯膠、纖維素衍生物、藻酸、等等）、木 質素衍生物、膨潤土、合成之水溶性聚合物（例如聚乙烯 醇、聚乙烯吡略啶酮、聚丙烯酸 '等等）、ΡΑΡ(磷酸異丙 醋（acidic isopropyl phosphate))、ΒΗΤ(2,6-二-第三丁基-4-甲基酚）及ΒΗΑ(2-第三丁基_4-甲氧基酚與3_第三丁基· 4-甲氧基酚）、植物油類、礦物油類、界面活性劑 '脂肪 -9 - 201120026 酸類及脂肪酸酯類。 用於片狀調配物之基本材料的例子包括由紙諸如凹版 印刷紙及牛皮紙製成的基本材料；纖維基本材料，例如， 織物、非織物及纖維之紡織混紡物，諸如尼龍纖維；及樹 脂薄膜。 在本發明之稻蝨科昆蟲防制組成物中，化合物I及化 合物Π之總量（在下文中稱爲“本發明活性成分之量”）通常 爲在從〇.〇1至95重量％，較佳爲從0.1至80重量％，更 佳爲從1至60重量％之範圍內。當本發明之稻蝨科昆蟲 防制組成物被調配成可乳化濃縮物、可溶性濃縮物、水溶 性粉劑（例如，水溶性粒劑）或可濕性粉劑（例如，水分散 性粒劑）時，在調配物中本發明活性成分之量通常爲在從 1至90重量％，較佳爲從1至80重量％，更佳爲從5至 60重量％之範圍內。當本發明之稻蝨科昆蟲防制組成物被 調配成油性溶液或粉劑時，在調配物中本發明活性成分之 量通常爲在從〇.〇1至90重量％，較佳爲從 0.1至50重 量％，更佳爲從0.1至20重量％之範圍內。當本發明之稻 蝨科昆蟲防制組成物被調配成粒劑時，在調配物中本發明 活性成分之量通常爲在從0.1至50重量％，較佳爲從0.5 至5 0重量％，更佳爲從1至2 0重量％之範圍內。 本發明之稻蝨科昆蟲防制組成物包含液體載體或固體 載體，其量爲 5至99.99重量％，較佳爲20至99.9重量 %，更佳爲40至99重量％。本發明之稻蝨科昆蟲防制組 成物包含界面活性劑，其量爲例如1至20重量％，較佳 -10- 201120026 爲從1至1 5重量％。 明確地說，當本發明之稻蝨科昆蟲防制組成物被調配 成可溶性濃縮物時，所得可溶性濃縮物包含2 0至9 0重量 %的水及1至20重量％(較佳爲 1至10重量％)的界面活 性劑。當本發明之稻蝨科昆蟲防制組成物被調配成懸浮濃 縮物諸如水性懸浮液或水性乳液時，例如，其可藉由將化 合物I及化合物II細分散於包含0.5至15重量％懸浮劑 (例如，一種能夠賦予保護性膠態或觸變性之物質）及約0 至1 〇重量％助劑（例如，消泡劑、防銹劑、穩定劑、分散 劑、滲透助劑、抗凍劑、防腐劑、殺真菌劑、等等）之水 中而獲得，如此使本發明活性成分之量變爲在從1至7 5 重量％之範圍內。 本發明之稻蝨科昆蟲防制組成物可與殺蟲劑、殺蟎 劑、殺線蟲劑、殺真菌劑、除草劑和/或植物生長調節劑 摻合或組合使用。 本發明之稻蝨科昆蟲防制組成物可發揮防稻蝨科昆蟲 的防制效果。 本發明之稻蝨科昆蟲防制組成物可展現防制作用之稻 蟲科昆蟲的例子包括褐稻飛蟲（^7〇；?〇/^0^〇/1^6«15)、白背 稻飛 1¾ (>Sogaie//a /wrci/era)及小褐飛蟲 。本發明之稻蝨科昆蟲防制組成物較佳係施用 至褐稻飛 1¾ (JV7/<3a rvα ia /wge”·?）。 稻蝨科昆蟲可藉由將有效量的化合物I及化合物II 施用至稻蝨科昆蟲或稻蝨科昆蟲的棲息地而被防制。本發 -11 - 201120026 明也包括一種防制稻蝨科昆蟲之方法，其包含將有效量的 化合物I及化合物II施用至稻蝨科昆蟲或稻蝨科昆蟲的 棲息地。 “有效量的化合物I及化合物II”在本文中係指化合物 I及化合物Π之總量，其表示能夠發揮防制稻蝨科昆蟲的 效果之量。 稻科昆蟲棲息地的例子包括稻田，且也包括稻蝨科昆 蟲可棲息之植物及土壤。 於分開劑型之化合物I及化合物II可同時施用至稻 蝨科昆蟲或稻蝨科昆蟲的棲息地。然而，考慮到施用之簡 單性，化合物I及化合物Π通常以本發明的稻蝨科昆蟲 防制組成物的形式施用。 施用化合物I及化合物Π之方法的例子包括植物葉 部的處理，諸如葉部施用；植物根部的處理；及植物耕種 區的處理，諸如土壤處理、及以淹沒方式施用至稻田。 葉部施用通常可藉由噴灑於稻蝨科昆蟲棲息的植物莖 及葉之表面而進行。當預期稻蝨科昆蟲棲息，在稻蝨科昆 蟲棲息於莖及葉之前，可噴灑於植物的莖及葉之表面。 植物根部的處理可藉由將包含固體載體諸如礦物粉的 化合物I及化合物II之調配物附著在根上而達到。 沒有限制將化合物I及化合物Π施用至植物之時 機。植物可在移植之前用化合物I及化合物Π處理。 土壤處理的例子包括噴灑在土壤上、摻入土壤及用化 學溶液濕透土壤。土壤處理可藉由將調配物諸如粒劑直接 -12- 201120026 施用至土壤、或藉由方法諸如使用設備諸如灌溉管、灌槪 輸送管及噴灑器之噴灑化學溶液、注入土壤、或化學溶液 淋滴而進行。 土壤處理對象的例子包括種植孔、種植行、種植孔附 近、種植行附近、耕種的整個表面、植物基部、植物間 隔、土壟、育苗箱、育苗盤及苗床。 土壤處理例如係在播種之前、在播種當時、在播種之 後立刻、在育苗階段、在移植之前、在移植時或在移植之 後的生長階段中進行。 在土壤處理中，植物可同時地用化合物I及化合物II 處理，且包含化合物I及化合物Π之固體肥料諸如糊劑 肥料可施用至土壤。 以淹沒方式施用至稻田或類似者的例子包括將化合物 I及化合物II施用至灌溉稻田之水表面，及將化合物I及 化合物Π施用至稻田灌溉用之進水。 以淹沒方式施用可藉由例如將包含化合物I及化合物 II之粒狀或液體組成物施用至稻田之水面或進水來進行。 在本發明之防制方法中，較佳地實施將有效量的化合 物I及化合物II以淹沒方式施用至稻田。 本發明也包括一種防制方法，其包含將有效量的包含 化合物I及化合物II之粒狀或液體組成物以淹沒方式施 用至稻田。 當化合物I及化合物II施用至稻蝨科昆蟲或稻蝨科 昆蟲的棲息地時，施用量係視稻蝨科昆蟲的品種或蟲口數 -13- 201120026 量、調配物之形式、施用時機、施用方法、施用 氣條件等等而改變，且通常以本發明活性成分之 1,000米2從0.1至1，000克，較佳爲從1至750 爲從1至500克之範圍內》 當使用粒劑、粉劑、油溶液或片狀調配物時 可以沒有稀釋的狀態施用，使得本發明活性成分 上述範圍內。 當使用可乳化濃縮物、可濕性粉劑、水溶性 分散性粒劑或懸浮濃縮物時，其通常可以在用水 本發明活性成分的量可在上述範圍內之後施用。 可乳化濃縮物、可濕性粉劑、水溶性粒劑、水分 或懸浮濃縮物在用水稀釋之後使用時，在所得水 本發明活性成分之濃度通常在從 0.1至10,000 圍內。 稻蝨科昆蟲棲息之植物的例子包括玉米、稻 大麥、裸麥、燕麥及高梁。本發明之組成物及防 佳可施用至稻子。上述植物可爲以育種方法或基 術改良之植物。 【實施方式】 本發明將藉由調配例及測試例更詳細地說明 於限制本發明。在該等實例中，除非另有指示， 表示重量份。 地點、天 量計爲每 克，更佳 ，其通常 之量可在 粒劑、水 稀釋致使 例如，當 散性粒劑 稀釋液中 ppm之範 、小麥、 制方法較 因改造技 ，並不用 術語“份” -14- 201120026 調配例ι(可乳化濃縮物） 將10份的聚氧乙烯苯乙烯基苯基醚及5份的十 基苯磺酸鈣加至由10份的化合物（1)至（3)中的任一 10份的化合物Π在32.5份的二甲苯及32.5份的二 甲醯胺的混合物所形成的溶液中。徹底地攪拌該混合 獲得可乳化濃縮物。 調配例2(可濕性粉劑） 將2份的化合物（1)至（3)中的任一者及20份的化 II加至5份的硫酸月桂酯鈉、2份的木質素擴酸銘、 的合成水合二氧化矽細粉及5 5份的矽藻土的混合物 徹底地攪拌該混合物以獲得可濕性粉劑。 調配例3(懸浮濃縮物） 將2份的化合物（1)至（3 )中的任一者及8份的化 II加至5份的聚氧乙烯苯乙烯基苯基醚硫酸鹽、20 1 %三仙膠水溶液、3份的膨潤石礦物質及62份的zK 勻混合物中。徹底地攪拌該混合物且然後用混砂機濕 磨以獲得懸浮濃縮物。 調配例4 (粒劑） 將〇 . 5份的化合物（1 )至（3 )中的任一者、1 〇份的 物Π、1份的合成水合二氧化矽、2份的木質素磺酸 30份的膨潤土及56.5份的高嶺土徹底地硏磨及攪拌 二烷 者及 甲基 物以 合物 16份 中。 合物 份的 之均 式硏 化合 鈣、 。將 -15- 201120026 水加至混合物中。將混合物徹底地揉合、製粒及然後乾燥 以獲得粒劑。 測試例1 (對褐飛風/wgens)之殺蟲活性 測試） 將化合物（1)(10毫克）溶解在1毫升的包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯，由Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含〇 . 〇 2體積％分散劑 [Dain (註冊商標），由Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋，以使水稀釋液可以具有預定濃度的化合物（1)。 將化合物11(10毫克）溶解在0.1毫升的包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯，由 Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含0.02體積％分散劑 [Dain (註冊商標），由Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋，以使水稀釋液可以具有預定濃度的化合物II。 將化合物（1)之水稀釋液及化合物Π之水稀釋液混合 以製備測試化學溶液。 二棵種植在紙盆中之於2.5葉齡的稻苗（水稻 sflHva):栽培品種：Hoshinoyume)用每2棵苗20毫升的 上述測試化學溶液噴灑。使該等稻苗風乾。然後，將各苗 -16- 201120026 放進包含4.8毫升水之玻瑀試管（直徑·· 30毫米；高度： 200毫米）中，及將1〇隻褐飛虱之第三齡幼蟲放進各試管 中。將試管放在—房間內（2 5。(：，濕度6 0 %)。在6天之 後，觀察測試幼蟲的存活或死亡。 實施除了只噴灑化合物（1)或化合物11的水稀釋液替 代上述測試化學溶液以外的相同測試作爲對照組。 在非處理部分中實施除了不噴灑上述測試化學溶液以 外的相同測試作爲對照組。 從觀察結果來看，用下列方程式（1)計算昆蟲死亡率 及用下列方程式（2)計算校正昆蟲死亡率。 方程式（1):昆蟲死亡率（％) = {在處理部分中之死亡 昆蟲數目/測試昆蟲之數目} X 100 方程式（2):校正昆蟲死亡率（％) = {(在處理部分中之 昆蟲死亡率-在非處理部分中之昆蟲死亡率）/(100 -在非 處理部分中之昆蟲死亡率）} X 100 上述測試重複兩次。平均値係顯示於表1中。 [表1] 測試化合物 濃度(ppm) 校正昆蟲死亡率(％) 化合物(1) 0.03 38 化合物⑴ 0.25 56 化合物Π 100 13 化合物(1) +化合物II 0.03 + 100 94 化合物(1)+化合物II 0.25 + 100 100 測S式例2 (對褐飛風之殺蟲活性測試） -17- 201120026 將化合物（2)(10毫克）（農藥殘留測試用之益達胺標準 產物，由和光純化學工業有限公司製造）溶解在1毫升的 包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯， 由Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由 和光純化學工業有限公司製造）中，然後用包含0.02體積 %分散劑[Dain (註冊商標），由Sumika-Takeda園藝產品股 份有限公司（現在名稱：住友化學園藝產品公司）製造]之 水稀釋，以使水稀釋液可以具有預定濃度的化合物（2)。 將化合物11(10毫克）溶解在0.1毫升的包含SORGEN TW-20(產品名稱；去水山梨醇脂肪酸酯，由 Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用0.02體積％分散劑[Dain (註冊商標），由Sumika-Takeda園藝產品股份有限公司（現 在名稱：住友化學園藝產品公司）製造]之水稀釋，以使水 稀釋液可以具有預定濃度的化合物II。 將化合物（2)之水稀釋液及化合物II之水稀釋液混合 以製備測試化學溶液。 二棵種植在紙盆中之於2.5葉齡的稻苗（水稻（Οαζα Μίίνα);栽培品種：Hoshinoyume)用每2棵苗20毫升的 上述測試化學溶液噴灑。使該等稻苗風乾。然後，將各苗 放進包含4.8毫升水之玻璃試管（直徑：30毫米；高度： 200毫米）中，及將10隻褐飛虱之第三齡幼蟲放進各試管 中。將試管放在一房間內（25 °C，濕度60%)。在6天之 後，觀察測試幼蟲的存活或死亡。 -18- 201120026 實施除了只噴灑化合物（2)或化合物II的水稀釋液替 代上述測試化學溶液以外的相同測試作爲對照組。 在非處理部分中實施除了不噴灑上述測試化學溶液以 外的相同測試作爲對照組。 從觀察結果來看，以如測試例1之相同方式，用方程 式（1)計算昆蟲死亡率及用方程式（2)計算校正昆蟲死亡 率。 上述測試重複兩次。平均値係顯示於表2中。 [表2] 測試化合物 濃度(PPm) 校正昆蟲死亡率(％) 化合物(2) 0.2 0 化合物(2) 3.1 27 化合物II 100 7 化合物(2) +化合物II 0.2+100 93 化合物(2) +化合物II 3.1 + 100 100 測試例3 (對褐飛虱之殺蟲活性測試） 將化合物（3)之商業上可得之調配物（產品名稱： Actara (註冊商標）；水溶性顆粒，由 Syngenta公司製造） 用包含0_02體積％分散劑[Dain (註冊商標），由Sumika-Takeda園藝產品股份有限公司（現在名稱：住友化學園藝 產品公司）製造]之水稀釋，以使水稀釋液可以具有預定濃 度的化合物（3)。 將化合物11(10毫克）溶解在0.1毫升的包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯，由 Dai-Ichi -19- 201120026201120026 VI. Description of the invention [Technical field to which the invention pertains] The present invention relates to a rice control group (£> e /;? /ι ac / C? ae ) insect control composition and a rice blast insect control method . [Prior Art] A nicotinic acetylcholine receptor agonist having a control effect against rice blast insects has been known so far (see, for example, JP-A 3-157308, JP-A 2001-072678, and agricultural and food chemistry Journal (journai 〇f Agricultural and Food Chemistry), 1994, 42 , pp. 2917-2921) ° However, there is still a need for an anti-formulation that has a high control effect on rice blast insects. SUMMARY OF THE INVENTION An object of the present invention is to provide a rice blast insect control composition and a rice blast insect control method which have an excellent control effect against rice worm insects. The inventors of the present invention conducted intensive studies and found that by using at least one nicotine acetylcholine selected from the group consisting of clothianidin, imidacloprid, and thiamethoxam The receptor agonist used N-(2-ethylhexyl)-5-norbornene-2,3-carboximine to improve the control activity of the rice-sucking insects. The present invention has thus been completed. The present invention provides: [1] a rice cockroach insect control composition comprising at least one selected -5 - 201120026 free konidine (〇丨〇111丨311丨(1丨11), 达达amine (丨Nicotinic acetylcholine receptor agonist and 1^-(2-ethylhexyl)-5_norpin in a group consisting of 111丨(13(:1(^1^) and thiamethoxam) Alkenyl-2,3-dimethylimine as an active ingredient; [2] A pest control composition according to [1], wherein a nicotinic acetylcholine receptor agonist is N-(2-B The weight ratio of hexyl)-5-northene-2,3-dimethylimine is nicotinic acetylcholine receptor agonist/N-(2-ethylhexyl)-5-norbornene- 2,3-dimethylimine is expressed in the range of 1/0.1 to 1/10,000; [3] is a method for controlling an insect of the genus Oryzae, which comprises an effective amount of at least one selected from the group consisting of konidine, Nicotine acetylcholine receptor agonist and N-(2-ethylhexyl)-5-northene-2,3-dimethylimine imine in a group consisting of idadine and cytosine The habitat of the rice blast or the rice blast; [4] according to [3] the method of controlling the insects of the rice blast, wherein the rice blast is brown (Nilaparvata lugens); [5] According to [3] the method of controlling the insects of the rice blast, wherein the habitat of the rice blast is a rice field. [6] A method for controlling insects of the genus Oryzae, which comprises An effective amount of at least one nicotinic acetylcholine receptor agonist selected from the group consisting of konidine, edetamine, and cytosine and Ν·(2-ethylhexyl)-5-norbornene- 2,3-dimethylimine is applied to the paddy field in a submerged manner; [7] a method for controlling an insect of the genus Oryzae, comprising an effective amount comprising at least one selected from the group consisting of konidine, edamine, and speed a group of nicotine acetylcholine receptor agonists and N-(2-ethylhexyl)-5-northene-2,3-dimethylimine granules or liquid compositions of subgroups Mode of application to rice-6 - 201120026 field; and [8] - at least one nicotinic acetylcholine receptor agonist selected from the group consisting of konidine, edetamine and cytosine and N-( Use of 2-ethylhexyl)-5-northene-2,3-dimethylimine in the prevention of rice blast insects. The insect control composition of the rice blast family according to the present invention acts as a rice blast resistant insect Excellent anti-effect DETAILED DESCRIPTION OF THE INVENTION The rice blast insect control composition of the present invention contains at least one selected from the group consisting of konidine (hereinafter, sometimes referred to as "compound (1)"), edaramin (hereinafter, sometimes, Nicotine acetylcholine receptor agonists, also referred to as "compound (2)") and cytosine (hereinafter sometimes referred to as "compound (3)") (hereinafter, Also referred to as "compound I") and N-(2-ethylhexyl)-5-northene-2,3-dimethylimine (hereinafter sometimes referred to as "compound") as Active ingredient. Cotinide can be prepared, for example, according to the method described in JP-A 3-157308. The edaramine can be prepared, for example, according to the method described in JP-A 61-267575. The speed can be prepared, for example, according to the method described in JP-A 6-183918. N-(2-ethylhexyl)-5-norbornene-2,3-dimethylimine is a compound called MGK264. N-(2-ethylhexyl)-5-norzide-2,3-dimethylhydrazine The imine is commonly used as a 201120026 synergist for pyrethroid chemicals or organophosphorus chemicals. In the rice blast insect control composition of the present invention, the weight ratio of the compound hydrazine (Compound 1 / Compound II) is usually 1 / 100,000, preferably 1 / 0.1 to 1 / 1 0, 000, but the combination The weight ratio of the substance is not particularly limited as long as the effect of the group is not lost. The rice blast insect control composition of the present invention can be simply a mixture of chemical compounds. The insect control of the rice blast family of the present invention can be formulated into an emulsifiable concentrate concentrate, a wettable powder, a water-dispersible granule by mixing the compound I, the compound II and an inert carrier, adding a surfactant and other auxiliaries. Agents, water-soluble powder granules, suspension concentrates such as aqueous suspensions or aqueous emulsion granules, aerosols, oily solutions, microcapsules or substances. Examples of inert carriers including solid carriers, liquid carriers, and gas-carrying solid carriers include natural or synthetic minerals, kaolin, talc, bentonite, sericite, quartz, sulfur, calcium oxalate, diatomaceous earth, pumice, calcite, sea blisters. Stone, dolomite alumina, vermiculite and perlite; fine particles such as sawdust, corn husk and tobacco stem; gelatin, petrolatum and paraffin oil, methyl cilia and lard. Examples of the liquid carrier include aromatic or aliphatic hydrocarbons such as diphenyl, alkylnaphthalene, phenyldimethylphenylethane, kerosene, gas oil, hexane, and liquid paraffin; halogenated hydrocarbons such as chlorobenzene, dichloroethane Compound I is 1/0.01 to the complex I of the compound I and the composition of the composition and the random addition, soluble agent, water soluble, powder, flakes such as clay, carbon, carbon, sand, cob, Coumarin, sheep toluene, methyl hexane, ring, dichloromethyl-8- 201120026 alkane and trichloroethane; alcohols such as methanol, ethanol, isopropanol, butanol, hexanol, benzyl alcohol and ethylene glycol Ethers such as diethyl ether, ethylene glycol dimethyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, propylene glycol monomethyl ether, tetrahydrofuran and 1,4-dioxane; esters such as ethyl acetate And butyl acetate; ketones such as acetone, methyl ethyl ketone, methyl ethyl ketone, methyl isobutyl ketone, and cyclohexanone; nitriles such as acetonitrile and isobutyronitrile; alkyl carbonates such as carbonic acid Propyl esters; hydrazines such as dimethyl hydrazine; guanamines such as hydrazine, hydrazine-dimethylformamide and hydrazine, hydrazine-dimethyl hydrazine Amine; pyrrolidone such as hydrazine-methyl-2-pyrrolidone, hydrazine-ethyl-2-pyrrolidone and fluorenyl-octyl-2-pyrrolidone; imidazolium such as 1,3-dimethyl Keto-2-imidazolium: a vegetable oil such as soybean oil or cottonseed oil; plant essential oils such as orange oil, hyssop oil and lemon oil; and water. Examples of the gas carrier include propane gas, butane gas, liquefied petroleum gas, dimethyl ether, and carbon dioxide gas. Examples of the surfactant include alkyl sulfates, alkyl sulfonates, alkyl aryl sulfonates, alkyl aryl ethers and polyoxyethylene compounds thereof, polyethylene glycol ethers, and polyethylene glycol fatty acids. Esters, polyol esters, sugar alcohol derivatives, and polyoxyalkylene surfactants. Examples of other adjuvants for formulation include casein, gelatin, sugars (such as starch 'arabin gum, cellulose derivatives, alginic acid, etc.), lignin derivatives, bentonite, synthetic water-soluble polymers ( For example, polyvinyl alcohol, polyvinylpyrrolidone, polyacrylic acid 'etc., etc., ΡΑΡ (acidic isopropyl phosphate), hydrazine (2,6-di-t-butyl-4-methylphenol) And ΒΗΑ (2-tert-butyl 4-methoxyphenol and 3_t-butyl 4-methoxyphenol), vegetable oils, mineral oils, surfactants - fat-9 - 201120026 acid And fatty acid esters. Examples of the base material for the sheet-like formulation include a base material made of paper such as gravure paper and kraft paper; a fiber base material such as a woven fabric of a woven fabric, a non-woven fabric, and a fiber such as nylon fiber; and a resin film . In the rice blast insect control composition of the present invention, the total amount of the compound I and the compound hydrazine (hereinafter referred to as "the amount of the active ingredient of the present invention") is usually from 〇.〇1 to 95% by weight, It is preferably from 0.1 to 80% by weight, more preferably from 1 to 60% by weight. When the rice blast insect control composition of the present invention is formulated into an emulsifiable concentrate, a soluble concentrate, a water-soluble powder (for example, a water-soluble granule) or a wettable powder (for example, a water-dispersible granule) The amount of the active ingredient of the present invention in the formulation is usually in the range of from 1 to 90% by weight, preferably from 1 to 80% by weight, more preferably from 5 to 60% by weight. When the rice blast insect control composition of the present invention is formulated into an oily solution or powder, the amount of the active ingredient of the present invention in the formulation is usually from 〇1 to 90% by weight, preferably from 0.1 to 50% by weight, more preferably from 0.1 to 20% by weight. When the rice blast insect control composition of the present invention is formulated into a granule, the amount of the active ingredient of the present invention in the formulation is usually from 0.1 to 50% by weight, preferably from 0.5 to 50% by weight, More preferably, it is in the range of from 1 to 20% by weight. The rice blast insect control composition of the present invention comprises a liquid carrier or a solid carrier in an amount of 5 to 99.99% by weight, preferably 20 to 99.9% by weight, more preferably 40 to 99% by weight. The rice blast insect control composition of the present invention contains a surfactant in an amount of, for example, 1 to 20% by weight, preferably -10-201120026, from 1 to 15% by weight. Specifically, when the rice blast insect control composition of the present invention is formulated into a soluble concentrate, the resulting soluble concentrate contains 20 to 90% by weight of water and 1 to 20% by weight (preferably 1 to 10% by weight of surfactant. When the rice blast insect control composition of the present invention is formulated into a suspension concentrate such as an aqueous suspension or an aqueous emulsion, for example, it can be finely dispersed in a suspension containing 0.5 to 15% by weight of the compound I and the compound II. (for example, a substance capable of imparting protective colloidal or thixotropic properties) and about 0 to 1% by weight of an auxiliary agent (for example, an antifoaming agent, a rust inhibitor, a stabilizer, a dispersing agent, a penetration aid, an antifreezing agent) Obtained in water of a preservative, fungicide, etc., such that the amount of the active ingredient of the present invention is in the range of from 1 to 75 % by weight. The rice blast insect control composition of the present invention may be blended or used in combination with an insecticide, an acaricide, a nematicide, a fungicide, a herbicide, and/or a plant growth regulator. The insect control composition of the rice blast family of the present invention can exert the control effect against the insects of the rice blast family. Examples of the rice blast insect control composition of the present invention which can exhibit insect-resistant insects include the brown rice flying insect (^7〇;?〇/^0^〇/1^6«15), white back Rice fly 13⁄4 (>Sogaie//a /wrci/era) and small brown fly. The rice blast insect control composition of the present invention is preferably applied to the brown rice fly 13⁄4 (JV7/<3a rvα ia /wge"·?). The rice blast insect can be obtained by administering an effective amount of the compound I and the compound. II is applied to the habitat of the genus Oryzae or the genus Oryzae, and is also protected. The method of preventing ricinidae insects comprising an effective amount of Compound I and Compound II is also included in the present invention. Applied to the habitat of the genus Oryzae or the genus Oryzae. "An effective amount of Compound I and Compound II" herein refers to the total amount of Compound I and the hydrazine of the compound, which means that it can play a defense against Oryzae The amount of effect. Examples of rice insect habitats include rice fields, and also include plants and soils in which the rice blasts can inhabit. Compounds I and II in separate dosage forms can be applied simultaneously to the rice blast or the rice blast. However, in view of the simplicity of application, the compound I and the compound oxime are usually applied in the form of the rice blast insect control composition of the present invention. Examples of the method of applying the compound I and the compound hydrazine include plant leaves. Treatment, such as leaf application; treatment of plant roots; and treatment of plant cultivation areas, such as soil treatment, and application to paddy fields in a submerged manner. Leaf application can usually be carried out by spraying on plant stems inhabited by rice blasts and The surface of the leaf is carried out. When the Insects are expected to inhabit, the Insects can be sprayed on the surface of the stems and leaves of the plants before they inhabit the stems and leaves. The roots of the plants can be treated by containing solid carriers such as minerals. The formulation of the powdered compound I and the compound II is attached to the root. There is no limitation on the timing of applying the compound I and the compound to the plant. The plant can be treated with the compound I and the compound before the transplantation. Examples of the soil treatment include spraying Soil, incorporation into the soil, and soaking the soil with a chemical solution. The soil treatment can be applied to the soil by applying a formulation such as granules directly -12- 201120026, or by methods such as the use of equipment such as irrigation pipes, irrigation pipes and The sprayer is sprayed with a chemical solution, injected into the soil, or dripped with a chemical solution. Examples of soil treatment objects include planting , planting rows, near planting holes, near planting rows, whole surface of cultivation, plant bases, plant spacing, soil ridges, nursery boxes, seedling trays and seedbeds. Soil treatments are for example before planting, at planting, immediately after sowing In the seedling stage, before the transplant, at the time of transplantation, or during the growth stage after the transplant. In the soil treatment, the plant can be simultaneously treated with the compound I and the compound II, and the solid fertilizer containing the compound I and the compound 诸如The paste fertilizer can be applied to the soil. Examples of application to the paddy field or the like in a submerged manner include application of the compound I and the compound II to the surface of the irrigated rice field, and application of the compound I and the compound hydrazine to the influent for rice field irrigation. Application in a submerged manner can be carried out, for example, by applying a granular or liquid composition comprising Compound I and Compound II to the surface of the rice paddy or into the water. In the method of the present invention, it is preferred to apply an effective amount of Compound I and Compound II to the paddy field in a submerged manner. The present invention also encompasses a method of controlling the application of an effective amount of a particulate or liquid composition comprising Compound I and Compound II to a paddy field in a submerged manner. When Compound I and Compound II are applied to the habitat of the genus Oryzae or the genus Oryzae, the application amount is based on the variety or number of insects of the genus Oryzae -13- 201120026, the form of the formulation, the timing of application, and the application. The method, the application gas condition and the like are changed, and usually from 0.1 to 1,000 g, preferably from 1 to 750, from 1 to 500 g, of the active ingredient of the present invention, when using granules, The powder, oil solution or tablet formulation may be applied in a state without dilution, so that the active ingredient of the present invention is within the above range. When an emulsifiable concentrate, a wettable powder, a water-soluble dispersible granule or a suspension concentrate is used, it can usually be applied after the amount of the active ingredient of the present invention can be within the above range. When the emulsifiable concentrate, the wettable powder, the water-soluble granule, the moisture or the suspension concentrate is used after being diluted with water, the concentration of the active ingredient of the present invention in the obtained water is usually from about 0.1 to 10,000. Examples of plants inhabited by rice blasts include corn, rice barley, rye, oats and sorghum. The composition and the prevention of the present invention can be applied to rice. The above plant may be a plant modified by a breeding method or a base. [Embodiment] The present invention will be described in more detail by limiting the examples and test examples. In these examples, parts by weight are indicated unless otherwise indicated. The location and the daily amount are, per gram, more preferably, the usual amount can be diluted in the granules and water to cause, for example, when the ppm of the granular granule diluent, the wheat, the method is more modified, and the term is not used. "Parts" -14- 201120026 Formulation example ι (emulsifiable concentrate) 10 parts of polyoxyethylene styrylphenyl ether and 5 parts of calcium decadecylbenzenesulfonate are added to 10 parts of compound (1) to Any 10 parts of the compound in (3) is in a solution of a mixture of 32.5 parts of xylene and 32.5 parts of dimethyl hydrazine. The mixing was thoroughly stirred to obtain an emulsifiable concentrate. Formulation Example 2 (Wettable powder) 2 parts of any one of the compounds (1) to (3) and 20 parts of the chemical II are added to 5 parts of sodium lauryl sulfate, and 2 parts of lignin is expanded. The mixture of synthetic hydrated ceria fine powder and 55 parts of diatomaceous earth thoroughly stirred the mixture to obtain a wettable powder. Formulation Example 3 (suspension concentrate) 2 parts of any one of the compounds (1) to (3) and 8 parts of the chemical II are added to 5 parts of polyoxyethylene styrylphenyl ether sulfate, 20 1 % Sanxian gum aqueous solution, 3 parts of bentonite minerals and 62 parts of zK homogeneous mixture. The mixture was thoroughly stirred and then wet-milled with a sand mixer to obtain a suspension concentrate. Formulation Example 4 (granules) 5 parts of any one of the compounds (1) to (3), 1 part of hydrazine, 1 part of synthetic hydrated cerium oxide, 2 parts of lignosulfonic acid 30 parts of bentonite and 56.5 parts of kaolin were thoroughly honed and stirred in 16 parts of dioxane and methylate. The aliquot of the compound is a combination of calcium and calcium. Add -15- 201120026 water to the mixture. The mixture is thoroughly kneaded, granulated and then dried to obtain granules. Test Example 1 (Insecticide activity test on brown fly/wgens) Compound (1) (10 mg) was dissolved in 1 ml containing SORGEN TW-20 (product name; sorbitan fatty acid ester, by Dai -Ichi Kogyo Seiyaku Co., Ltd.) Acetone (manufactured by Wako Pure Chemical Industries Co., Ltd.), and then contains 〇. 〇 2 vol% dispersant [Dain (registered trademark), by Sumika-Takeda Horticultural Products Co., Ltd. The water (manufactured by Sumitomo Chemical Horticultural Products Co., Ltd.) is diluted so that the water dilution can have a predetermined concentration of the compound (1). Compound 11 (10 mg) was dissolved in 0.1 ml of acetone containing SORGEN TW-20 (product name; sorbitan fatty acid ester, manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd.) (Yiheguang Purification Industry Co., Ltd.) Manufactured, and then diluted with water containing 0.02% by volume of a dispersant [Dain (registered trademark), manufactured by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) so that the water dilution can be Compound II has a predetermined concentration. A water dilution of the compound (1) and a water dilution of the compound hydrazine were mixed to prepare a test chemical solution. Two rice seedlings (rice sflHva) planted in a paper pot at 2.5 leaf age: cultivar: Hoshinoyume) were sprayed with 20 ml of the above test chemical solution per 2 shoots. The rice seedlings are allowed to air dry. Then, each seedling-16-201120026 was placed in a glass test tube (diameter · 30 mm; height: 200 mm) containing 4.8 ml of water, and a third instar larva of the brown planthopper was placed in each test tube. in. Place the tube in the room (2 5 (:, humidity 60%). After 6 days, observe the survival or death of the test larvae. Perform the water dilution instead of spraying only compound (1) or compound 11 instead of the above The same test except for the test chemical solution was used as a control group. The same test except that the above test chemical solution was not sprayed was used as a control group in the non-treated portion. From the observation results, the insect mortality rate and the use of the following equation (1) were calculated. The corrected insect mortality rate is calculated by the following equation (2): Equation (1): Insect mortality (%) = {Number of dead insects in the treated part / Number of tested insects} X 100 Equation (2): Correcting insect mortality ( %) = {(Insect mortality in the treatment section - Insect mortality in the non-treated section) / (100 - Insect mortality in the non-treated section)} X 100 The above test was repeated twice. It is shown in Table 1. [Table 1] Test compound concentration (ppm) Corrected insect mortality (%) Compound (1) 0.03 38 Compound (1) 0.25 56 Compound Π 100 13 Compound (1) + Compound II 0.03 + 1 00 94 Compound (1) + Compound II 0.25 + 100 100 Test S Example 2 (Test for insecticidal activity against brown wind) -17- 201120026 Compound (2) (10 mg) (Yida of pesticide residue test) The amine standard product, manufactured by Wako Pure Chemical Industries Co., Ltd., was dissolved in 1 ml of acetone containing SORGEN TW-20 (product name; sorbitan fatty acid ester, manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd.) Was diluted with water containing 0.02% by volume of dispersant [Dain (registered trademark), manufactured by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.), The aqueous dilution may have a predetermined concentration of the compound (2). Compound 11 (10 mg) is dissolved in 0.1 ml of SORGEN TW-20 (product name; sorbitan fatty acid ester by Dai-Ichi Kogyo Seiyaku) Acetone (manufactured by Heguang Purification Industry Co., Ltd.), and then 0.02% by volume of dispersant [Dain (registered trademark), by Sumika-Takeda Horticultural Products Unit Diluted with water of the Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) so that the aqueous dilution can have a predetermined concentration of Compound II. Mix the aqueous dilution of Compound (2) with the aqueous dilution of Compound II to A test chemical solution was prepared. Two 2.5-year-old rice seedlings (rice (Οαζα Μίίνα); cultivar: Hoshinoyume) planted in a paper pot were sprayed with 20 ml of the above test chemical solution per 2 shoots. The rice seedlings are allowed to air dry. Then, each seedling was placed in a glass test tube (diameter: 30 mm; height: 200 mm) containing 4.8 ml of water, and 10 third-instar larvae of brown planthopper were placed in each test tube. Place the tube in a room (25 ° C, humidity 60%). After 6 days, the survival or death of the test larvae was observed. -18- 201120026 The same test except that the above test chemical solution was replaced with only the aqueous dilution of Compound (2) or Compound II was used as a control group. The same test except that the above test chemical solution was not sprayed was carried out as a control group in the non-treated portion. From the observation results, the insect mortality rate was calculated by the equation (1) and the corrected insect mortality rate was calculated by the equation (2) in the same manner as in Test Example 1. The above test was repeated twice. The average tether is shown in Table 2. [Table 2] Test compound concentration (PPm) Corrected insect mortality (%) Compound (2) 0.2 0 Compound (2) 3.1 27 Compound II 100 7 Compound (2) + Compound II 0.2 + 100 93 Compound (2) + Compound II 3.1 + 100 100 Test Example 3 (Test for insecticidal activity against brown planthopper) Commercially available formulation of compound (3) (product name: Actara (registered trademark); water-soluble granules, manufactured by Syngenta Diluted with water containing 0_02% by volume of dispersant [Dain (registered trademark), manufactured by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) so that the water dilution can have a predetermined concentration Compound (3). Dissolve Compound 11 (10 mg) in 0.1 ml containing SORGEN TW-20 (product name; sorbitan fatty acid ester, by Dai-Ichi -19- 201120026
Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含0.02體積％分散劑 [Dain (註冊商標），由Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋，以使水稀釋液可以具有預定濃度的化合物II。 將化合物（3)之水稀釋液及化合物II之水稀釋液混合 以製備測試化學溶液。 二棵種植在紙盆中之於2.5葉齡的稻苗（水稻 s<3ii_va);栽培品種：Hoshinoyume)用每2棵苗20毫升的 上述測試化學溶液噴灑。使該等稻苗風乾。然後，將各苗 放進包含4.8毫升水之玻璃試管（直徑：30毫米；高度： 200毫米）中，及將10隻褐飛虱之第三齡幼蟲放進各試管 中。將試管放在一房間內（25 °C，濕度60%)。在6天之 後，觀察測試幼蟲的存活或死亡。 實施除了只噴灑化合物（3)或化合物II的水稀釋液替 代上述測試化學溶液以外的相同測試作爲對照組。 在非處理部分中實施除了不噴灑上述測試化學溶液以 外的相同測試作爲對照組。 從觀察結果來看，以如測試例1之相同方式’用方程 式（1)計算昆蟲死亡率及用方程式（2)計算校正昆蟲死亡 率〇 上述測試重複兩次。平均値係顯示於表3中。 -20- 201120026 [表3] 測試化合物 濃度(ppm) 校正昆蟲死亡率(％) 化合物(3) 0.05 29 化合物(3) 0.2 57 化合物II 100 7 化合物⑶+化合物II 0.05 + 100 71 化合物⑶+化合物II 0.2 + 100 100 測試例4 (以淹沒方式施用至褐飛虱之殺蟲效果測試） 將化合物（1)(10毫克）溶解在1毫升的包含SORGEN TW-20(產品名稱；去水山梨醇脂肪酸酯，由 Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含0.02體積％分散劑 [Dain (註冊商標），由 Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋’以使水稀釋液可以具有預定濃度的化合物（1 )。 將化合物（2)(10毫克）（農藥殘留測試用之益達胺標準 產物，由和光純化學工業有限公司製造）溶解在1毫升的 包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯， 由Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由 和光純化學工業有限公司製造）中，然後用包含0.02體積 %分散劑[Dain (註冊商標），由Sumika-Takeda園藝產品股 份有限公司（現在名稱：住友化學園藝產品公司）製造]之 水稀釋’以使水稀釋液可以具有預定濃度的化合物（2)。 將化合物11(10毫克）溶解在0.1毫升的包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯，由Dai-Ichi -21 - 201120026Acetone (manufactured by Kogyo Seiyaku Co., Ltd.), which is made of 0.02% by volume of dispersant [Dain (registered trademark), by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo) The chemical horticultural product company) is diluted with water so that the water dilution can have a predetermined concentration of compound II. A water dilution of the compound (3) and a water dilution of the compound II were mixed to prepare a test chemical solution. Two 2.5-year-old rice seedlings (rice s<3ii_va) planted in paper cones; cultivar: Hoshinoyume) were sprayed with 20 ml of the above test chemical solution per 2 shoots. The rice seedlings are allowed to air dry. Then, each seedling was placed in a glass test tube (diameter: 30 mm; height: 200 mm) containing 4.8 ml of water, and 10 third-instar larvae of brown planthopper were placed in each test tube. Place the tube in a room (25 ° C, humidity 60%). After 6 days, the survival or death of the test larvae was observed. The same test except that the above test chemical solution was replaced with a water dilution in which only Compound (3) or Compound II was sprayed was used as a control group. The same test except that the above test chemical solution was not sprayed was carried out as a control group in the non-treated portion. From the observation results, the insect mortality was calculated by the equation (1) and the corrected insect mortality rate was calculated by the equation (2) in the same manner as in Test Example 1. The above test was repeated twice. The average tether is shown in Table 3. -20- 201120026 [Table 3] Test compound concentration (ppm) Corrected insect mortality (%) Compound (3) 0.05 29 Compound (3) 0.2 57 Compound II 100 7 Compound (3) + Compound II 0.05 + 100 71 Compound (3) + compound II 0.2 + 100 100 Test Example 4 (Insecticide test for submerged application to brown planthopper) Compound (1) (10 mg) was dissolved in 1 ml of SORGEN TW-20 (product name; sorbitan) A fatty acid ester, manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd., acetone (manufactured by Wako Pure Chemical Industries Co., Ltd.), and then containing 0.02% by volume of a dispersant [Dain (registered trademark), by Sumika-Takeda horticultural product The company (produced by Sumitomo Chemical Horticultural Products Co., Ltd.) is diluted with water so that the water dilution can have a predetermined concentration of the compound (1). Compound (2) (10 mg) (the etadaamine standard product for pesticide residue test, manufactured by Heguang Purification Industry Co., Ltd.) was dissolved in 1 ml containing SORGEN TW-20 (product name; sorbitan fatty acid) Ester (manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd.) in acetone (manufactured by Wako Pure Chemical Industries Co., Ltd.), and then contains 0.02% by volume of a dispersant [Dain (registered trademark), limited by Sumika-Takeda horticultural products The company (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) manufactures water diluted 'so that the water dilution can have a predetermined concentration of compound (2). Dissolve Compound 11 (10 mg) in 0.1 ml containing SORGEN TW-20 (product name; sorbitan fatty acid ester, by Dai-Ichi-21 - 201120026
Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含0.02體積％分散劑 [Dain (註冊商標），由Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋，以使水稀釋液可以具有預定濃度的化合物II。 將化合物（1)之水稀釋液或化合物（2)之水稀釋液與化 合物Π之水稀釋液混合以製備測試化學溶液。 將稻苗（水稻（Oryza βίϊίίνα);栽培品種：Hoshinoyume) 種植在1/10,〇〇〇a Wagner盆中且生長直到第四真葉階段。 在灌槪該盆以使水深度變成3公分之後，將10毫升的上 述測試化學溶液施用至水表面上。在施用之後立刻用尼龍 網覆蓋稻苗及將10隻褐飛虱之第三齡幼蟲放進網中。將 盆放在溫室（23 °C)內。在6天之後，觀察測試幼蟲的存活 或死亡。 在非處理部分中實施除了不施用上述測試化學溶液以 外的相同測試作爲對照組。 從觀察結果來看，以如測試例1之相同方式，用方程 式（1)計算昆蟲死亡率及用方程式（2)計算校正昆蟲死亡 率。 上述測試重複三次。平均値係顯不於表4中。 [表 4] _ 測試化合物 施用量 (克/1000 米2) 昆蟲死亡率 (%) 校正昆蟲死亡率 (%) 化合物⑴+化合物II 1.25 + 500 93 93 化合物(2) +化合物π 10 + 500 97 97 -22- 201120026 測試例5 (以淹沒方式施用至褐飛虱之殺蟲效果測試） 將化合物（3 )(1 0毫克）（農藥殘留測試用之賽速安標準 產物，由和光純化學工業有限公司製造）溶解在1毫升的 包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸醋， 由Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由 和光純化學工業有限公司製造）中，然後用包含0.02體積 %分散劑[D a i η (註冊商標），由S u m i k a - T a k e d a園藝產品股 份有限公司（現在名稱：住友化學園藝產品公司）製造]之 水稀釋，以使水稀釋液可以具有預定濃度的化合物（3)。 將化合物11(10毫克）溶解在0.1毫升的包含SORGEN TW-20 (產品名稱；去水山梨醇脂肪酸酯，由Dai-Ichi Kogyo Seiyaku股份有限公司製造）之丙酮（由和光純化學 工業有限公司製造）中，然後用包含0.0 2體積％分散劑 [Dain (註冊商標），由 Sumika-Takeda園藝產品股份有限 公司（現在名稱：住友化學園藝產品公司）製造]之水稀 釋，以使水稀釋液可以具有預定濃度的化合物II。 將化合物（3)之水稀釋液及化合物II之水稀釋液混合 以製備測試化學溶液。 將稻苗（水稻（0/^20 50!?/"(2);栽培品種：11〇811丨110>〇111^) 種植在1 /1 0,000a Wagner盆內且生長直到第四真葉階段。 在灌溉該盆以使水深度變成3公分之後，將1 0毫升的上 述測試化學溶液施用至水表面上。在施用之後立刻，用尼 龍網覆蓋稻苗及將10隻褐飛虱之第三齡幼蟲放進網中。 -23- 201120026 將盆放在溫室（23°C)內。在6天之後’觀察測試幼蟲的存 活或死亡。 在非處理部分中實施除了不施用上述測試化學溶液以 外的相同測試作爲對照組。 從觀察結果來看，以如測試例1之相同方式，用方程 式（1)計算昆蟲死亡率及用方程式（2)計算校正昆蟲死亡 率。 '上述測試重複三次。平均値係顯示於表5中。 [表5] 測試化合物 施用量(克/1000米2) 校正昆蟲死亡率(％) 化合物(3) +化合物Π 1.25 + 500 82 工業適用性 ®據本發明，可能提供一種具有優良防制稻蝨科昆蟲 @ ¥之稻蝨科昆蟲防制組成物及一種稻蝨科昆蟲防制方 法0 -24-Acetone (manufactured by Kogyo Seiyaku Co., Ltd.), which is made of 0.02% by volume of dispersant [Dain (registered trademark), by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo) The chemical horticultural product company) is diluted with water so that the water dilution can have a predetermined concentration of compound II. The aqueous dilution of the compound (1) or the aqueous dilution of the compound (2) is mixed with the aqueous dilution of the compound to prepare a test chemical solution. Rice seedlings (Oryza βίϊίίνα; cultivar: Hoshinoyume) were planted in 1/10, 〇〇〇a Wagner pots and grown until the fourth true leaf stage. After the pot was filled to make the water depth 3 cm, 10 ml of the above test chemical solution was applied to the surface of the water. Immediately after application, the rice seedlings were covered with nylon mesh and the third instar larvae of 10 brown planthoppers were placed in the net. Place the pot in the greenhouse (23 °C). After 6 days, the survival or death of the test larvae was observed. The same test except that the above test chemical solution was not applied was carried out as a control group in the non-treated portion. From the observation results, the insect mortality rate was calculated by the equation (1) and the corrected insect mortality rate was calculated by the equation (2) in the same manner as in Test Example 1. The above test was repeated three times. The average tether is not shown in Table 4. [Table 4] _ Test compound application amount (g/1000 m2) Insect mortality (%) Corrected insect mortality (%) Compound (1) + Compound II 1.25 + 500 93 93 Compound (2) + Compound π 10 + 500 97 97 -22- 201120026 Test Example 5 (Insecticide test applied to brown planthopper by submerged method) Compound (3) (10 mg) (Sympanol standard product for pesticide residue test, from Heguang Purification Industry Co., Ltd.) Dissolved in 1 ml of acetone (manufactured by Wagen & Yamori Chemical Co., Ltd.) containing SORGEN TW-20 (product name; sorbitan fatty acid vinegar, manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd.) Then, it is diluted with water containing 0.02% by volume of a dispersant [D ai η (registered trademark), manufactured by Sumika - Takeda Horticultural Products Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) so that the water dilution can be Compound (3) having a predetermined concentration. Compound 11 (10 mg) was dissolved in 0.1 ml of acetone containing SORGEN TW-20 (product name; sorbitan fatty acid ester, manufactured by Dai-Ichi Kogyo Seiyaku Co., Ltd.) (Yiheguang Purification Industry Co., Ltd.) Manufactured, and then diluted with water containing 0.02% by volume of a dispersant [Dain (registered trademark), manufactured by Sumika-Takeda Horticultural Products Co., Ltd. (now name: Sumitomo Chemical Horticultural Products Co., Ltd.) to make a water dilution It may have a predetermined concentration of Compound II. A water dilution of the compound (3) and a water dilution of the compound II were mixed to prepare a test chemical solution. Rice seedlings (rice (0/^20 50!?/"(2); cultivar: 11〇811丨110>〇111^) were planted in 1 / 1 0,000a Wagner pots and grown until the fourth true leaf After irrigating the pot to make the water depth 3 cm, 10 ml of the above test chemical solution was applied to the surface of the water. Immediately after application, the rice seedlings were covered with a nylon mesh and 10 brown planthoppers were covered. The third instar larvae were placed in the net. -23- 201120026 The pots were placed in the greenhouse (23 ° C). After 6 days 'observation test the survival or death of the larvae. In the non-treated part, except the above test chemical solution was not applied. The same test was used as a control group. From the observation results, the insect mortality was calculated by the equation (1) and the corrected insect mortality was calculated by the equation (2) in the same manner as in Test Example 1. The above test was repeated three times. The average lanthanide is shown in Table 5. [Table 5] Test compound application amount (g/1000 m 2 ) Corrected insect mortality (%) Compound (3) + Compound Π 1.25 + 500 82 Industrial Applicability® According to the present invention, May provide an excellent defense against rice blast insects @ ¥ Prevention planthopper Coleoptera composition, and one planthopper Coleoptera Prevention method 0-24-