TW200918983A - Forming method of a silicone gel contact lens and its structure - Google Patents

Forming method of a silicone gel contact lens and its structure Download PDF

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Publication number
TW200918983A
TW200918983A TW96139563A TW96139563A TW200918983A TW 200918983 A TW200918983 A TW 200918983A TW 96139563 A TW96139563 A TW 96139563A TW 96139563 A TW96139563 A TW 96139563A TW 200918983 A TW200918983 A TW 200918983A
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Taiwan
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contact lens
silicone
forming
soluble
lens
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TW96139563A
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Chinese (zh)
Inventor
mo-wei Hong
zhi-hong Zhang
zhi-qin Liang
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mo-wei Hong
zhi-hong Zhang
zhi-qin Liang
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Priority to TW96139563A priority Critical patent/TW200918983A/en
Publication of TW200918983A publication Critical patent/TW200918983A/en

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Abstract

This invention provides a forming method a silicone gel contact lens and its structure. The method mainly utilizes a mixture of a soft, translucent and elastic silicone base material, and a filling material that is water soluble (or soluble in an organic solvent) to form the lens main body. By taking advantage of the water solubility and organic solvent solubility characteristics of the filling material, the filling material is then extracted from the lens main body by using water or organ solvent, thereby forming interconnected pore space that is densely distributed inside and on the surface of the lens main body, and is suitable for aerated tear to flow through, so as to increase the level of comfort and usage duration when wearing such contact lens. This method is also applicable in making other pharmaceutical material required in optical field such as artificial crystal.

Description

200918983 五 中文發明摘要: —種藤隱麵鏡之麵施及其結構 軟具彈性之矽膠基材與水溶性(或有機溶齊 明粢 混合後成型爲一鏡片本體,利用該塡充材“材料 溶臟之特性,讎鏡片本體用水或有機溶劑 密集分佈且相互連通之孔洞間隙,以形成 以提昇配戴隱形眼鏡之舒適性及使用時間f,籍 造其他的光學醫藥材料如:人工晶體等。此法亦可應用於製 六、 英文發明摘要:七、 指定代表圖: (一) 本案指定代表圖為:第(3 )圖。 (二) 本代表圖之元件符號簡單說明: 1.....鏡片本體 2.....子L洞 3.....眼球表面 八、本案若有化學式時,請揭示最能顯示發明特徵的化學式·· 九、發明說明: 【發明所屬之技術領域】 本發明是有關一種砍膠隱形眼鏡之成型方法及;M:結構,t 指一種可延長配戴時間、避免長期使用引起眼球病^之隱开^ 鏡成型方法及其結構。 〃 【先前技術】 隨著美觀及便利性之需求’各種隱形眼鏡之使用也曰漸# 遍’而隱形眼鏡約略可分爲硬式及軟式鏡片,其中以軟式鏡^ 配戴上較爲舒適,而傳統之隱形眼鏡結構及其配戴情形,7¾% 弟1圖所示,配戴時,該隱型眼鏡鏡片1 0係置於眼球表面3 200918983 前,藉以使進入眼球之光線預先產生折射,藉以達到矯正視力 之功效;然而,由於隱型眼鏡鏡片1 0 5令配戴時會緊貼眼球表 面3,使眼球時間無法充份接觸到空氣,若長時間配戴(超過 八小時)則會導致眼睛缺氧’致使配戴者產生眼睛會發紅(微 血管擴張)之極度不舒適感,所以材料的高透氧性對眼球細胞 非常重要,否則因爲配戴隱形眼鏡時間過長,會造成眼細胞的 缺氧而死,引起眼疾。 目前軟式隱形眼鏡之材料’一般以矽膠及水膠材質較爲常 見,其中: 1.水膠:雖具親水性,但透氧率低,且於乾燥的地方,鏡片會 變硬,使配戴者不舒適。 2·矽膠:矽膠聚合物雖然具有很高的透氧性,但不具親水性, 無法輸送營養液及排除廢物’且無法滲透水的隱形眼鏡,會 吸附(suet ion)於眼球’不易取下,不但視覺光學上有影響, 並且會造成眼睛不適與傷害,因此,不適合作爲延長戴用型 之隱形眼鏡材料。 3.水膠與矽膠之混製品(Ref 1-Ref 26):矽水凝膠材料則具備 上述之優點,其主要係利用矽膠(或含氟砂膠彳成份來形 透氧性;而水凝膠成份則提供輸送液體及隱形眼鏡的滑動性 需求,但是生產這種材料的設計與製備是非常困難的,因爲 要將兩種化學性質完全相反的原料混合在一起,而仍保有光 學上的淸晰度,這就有如將水和油混在一起,而仍能成爲淸 晰透光的薄片一樣的困難’主要原因就是油溶性的矽膠成份 無法溶於水溶性的水膠成份之中,所以當矽膠單體和親水性 的單體在一起時,通常會產生相分離現象,而令材料成爲渾 濁而不透明,也因爲如此,矽水凝膠材料雖具有上述兩傳統 材料之優點’但其材料之合成極爲不易,製造困難致使成本 高、難以推廣。 有鑑於習見之軟式隱形眼鏡結構有上述缺點,發明人乃針 對該些缺點硏究改進之道,終於有本發明產生。 【發明内容】 是以’本發明之主要目的在於提供一種矽膠隱形眼鏡之成 型方法,其具有較簡易之加工困難度,可有效降低生產成本、 200918983 提昇產品競爭力。 本發明之另一目的在於提供一種政膠隱形眼鏡之結構,其 可有效延長配戴使用時間,且可避免眼睛缺氧造成不適。 爲達成上述目的及功效,其所採行的技術手段包括:一「混 合」步驟,係將透明之矽膠基材與塡充材料相互均勻混合爲一 混合材料;一「成型」步驟,將該混合材料成型爲一鏡片本體; 一「萃取」步驟,將該鏡片本體內之塡充材料由矽膠基材中萃 取出。 藉由上述方法成型之鏡片本體,其於鏡片本體表面及內部 設有密集分佈且相互連通之孔洞。 爲使本發明的上述目的、功效及特徵可獲致更具體的暸 解,兹依下列附圖說明如下: 【實施方式】 請參第2、3圖所示,可知本發明之成型方法主要包括: 「混合」1 1、「成型」1 2及「萃取」1 3等步驟,其中該 「混合」11步驟係將不會聚合且具有水溶性的塡充材料 (如:水溶性的含矽的表面分散劑或水溶性矽膠)與可以聚合 的矽膠混合在一起,使之形成一均勻的混合材料,「成型」1 2步驟係將該混合材料利用標準的聚合方法合成爲一透明柔 軟具彈性之鏡片本體1,「萃取」13步驟則係將該鏡片本體 1內水溶性的塡充材料由矽膠基材中萃取出,如此一來,該矽 膠材質之鏡片本體1原來容納該水溶性的塡充材料之空間即 會形成密集且相互連通之孔洞2; 使用時,當該鏡片本體1SS戴於眼球表面3上,利用鏡片 本體1與空氣接觸,使其表面之淚液或生理食鹽水(人工淚液) 含有相當之氧氣,該含氧量豐富之淚液或生理食鹽水(人工淚 液)經滲透或配戴者眨眼(即眼皮對鏡片產生壓擠作用)會流 入上述分佈於鏡片本體1表面及內部之孔洞2中,再滲透至眼 球表面3,使眼球表面不斷有氧氣之補充’故長期配戴亦不會 有眼睛不適或缺氧發紅的現象;再者’由於該鏡片本體1就有 矽膠材質之高透氧性,加以具有可輸送液體的功能,其不但可 以幫助鏡片本體1的滑動,又能輸送養分及排除廢物,且因該 鏡片本體1具有孔洞2,因此不會如傳統矽膠鏡片般產生吸附 200918983 於眼球表面3上之不良作用。 依照本發明上述之矽膠隱形眼鏡結構,其由於該水溶性塡 充材料係可與矽]^混合’且於成型爲鏡片本體1後,該水溶性 塡充材料又極易經由水解方式去除,可能需要或不需經過 plasma處理因此’其整體之生產上並無較困難之瓶頸,可有 效降低生產之成本,進而提昇產品 競爭力。 本發明之鏡片聚合方式,可採任何聚合方式,如熱聚合或 紫外光聚合等,去促進聚合作用。熱聚合起始齊何如Lauroyl peroxide 5 isopropyl percarbonate , azobisisobutyronitrile等等’可用於適當高溫下產生自由 基而引發聚合作用。而光聚合起始劑則可是如aromatic alpha-hydroxyketone,或是 tertiary amine 加上 1 個 diketone 等等。 亦可加進另外的附加劑到此矽膠隱形眼鏡材料中,例如紫 外線吸收劑,顏料染料等等。另外爲了改進隱形眼鏡製程,若 有需要也可以加入脫模劑,溼潤劑等等。 應用實施例1 將以下的化學物混合均勻,所形成的溶液標明爲化學材料I methacryloxy propyl tris(trimethyl siloxysilane(TRIS) 47 parts methyl raethacrylate(MMA) 8 parts N,N-Dimethylacrylamide(DMAA) 42 parts200918983 Five Chinese invention summary: - the surface of the vine hidden mirror and its structure soft elastic silicone substrate and water-soluble (or organically dissolved Qi Ming 粢 mixed to form a lens body, using the 塡 filling material "material The characteristics of dissolving the dirt, the pores of the lens body are densely distributed and interconnected by water or organic solvent to form a contact to improve the comfort and use time of wearing contact lenses, and other optical medical materials such as artificial crystals. This method can also be applied to the system and abstracts of the invention: 7. The designated representative map: (1) The representative representative of the case is: (3). (2) The symbol of the representative figure is simple: 1... .. lens body 2.....sub-L hole 3.....eyeball surface 8. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention. · Nine, invention description: [Technology to which the invention belongs FIELD OF THE INVENTION The present invention relates to a method for forming a chopped contact lens and a structure of M: t, which refers to a method for forming a lens which can prolong the wearing time and avoid eyeball disease caused by long-term use, and a structure thereof. technology With the demand for beauty and convenience, the use of various contact lenses is also becoming more and more. The contact lenses can be roughly divided into hard and soft lenses, which are more comfortable to wear with soft mirrors, and the traditional contact lens structure. And its wearing situation, 73⁄4% brother 1 shown, when wearing, the contact lens 10 is placed on the surface of the eyeball 3 200918983, so that the light entering the eye is pre-refractive, so as to achieve the effect of correcting vision However, since the contact lens 100 will make it close to the surface of the eyeball when worn, the eyeball time will not be fully exposed to the air, and if worn for a long time (more than eight hours), the eye will be deprived of oxygen. The wearer's eyes will be extremely uncomfortable with redness (microvascular expansion), so the high oxygen permeability of the material is very important to the eye cells, otherwise the eye cells will be deprived of oxygen due to the long time of wearing the contact lenses. It causes eye diseases. At present, the materials of soft contact lenses are generally more common in silicone and water gel, among which: 1. Water gel: Although it is hydrophilic, it has low oxygen permeability and is dry. The lens will become hard and make the wearer uncomfortable. 2. Tannin: Although the silicone polymer has high oxygen permeability, it is not hydrophilic, and it can not transport nutrient solution and remove the waste's water-insoluble contact lens. It will not be easy to remove the eyeball, which will not only be visually optically affected, but also cause eye discomfort and injury. Therefore, it is not suitable as a contact lens material for extended wear. 3. Mixed product of water gel and silicone rubber (Ref 1-Ref 26): Hydrogel gel materials have the above advantages, mainly using silicone rubber (or fluorine-containing sand rubber to form oxygen permeability; while hydrogel components provide transport liquid and contact lenses) The slidability requirements, but the design and preparation of this material is very difficult, because the two chemically opposite materials are mixed together, while still retaining the optical clarity, which is like water and The oil is mixed together, but still can be the same as the light-transparent thin film. The main reason is that the oil-soluble silicone component cannot be dissolved in the water-soluble water-gel component, so when the silicone monomer and When the water-based monomers are together, phase separation usually occurs, and the material becomes turbid and opaque. Because of this, the hydrogel material has the advantages of the above two conventional materials, but the synthesis of the materials is extremely difficult, and the production is extremely difficult. Difficulties cause high costs and are difficult to promote. In view of the above-mentioned shortcomings of the soft contact lens structure, the inventors have made improvements to these disadvantages, and finally the present invention has been produced. SUMMARY OF THE INVENTION The main object of the present invention is to provide a method for forming a silicone contact lens, which has a relatively simple processing difficulty, can effectively reduce the production cost, and enhance the competitiveness of the product in 200918983. Another object of the present invention is to provide a structure of a political contact lens which can effectively extend the wearing time and avoid discomfort caused by oxygen deficiency of the eyes. In order to achieve the above objectives and effects, the technical means adopted include: a "mixing" step of uniformly mixing the transparent silicone substrate and the filling material into a mixed material; a "forming" step of mixing the mixture The material is formed into a lens body; an "extraction" step, the filling material in the lens body is extracted from the silicone substrate. The lens body formed by the above method is provided with holes which are densely distributed and communicate with each other on the surface and inside of the lens body. In order to achieve a more specific understanding of the above objects, functions and features of the present invention, the following description will be made in the following drawings: [Embodiment] Referring to Figures 2 and 3, it is understood that the molding method of the present invention mainly includes: Mixing "1", "forming" 1 2 and "extracting" 13 and the like, wherein the "mixing" step 11 is a water-soluble cerium-containing surface dispersion which is not polymerized and has water solubility. The agent or the water-soluble tannin extract is mixed with the polymerizable tannin to form a uniform mixed material, and the "forming" step is a method of synthesizing the mixed material into a transparent soft and flexible lens body by a standard polymerization method. 1. The step of "extracting" 13 is to extract the water-soluble filling material in the lens body 1 from the silicone substrate, so that the lens body 1 of the silicone material originally accommodates the water-soluble filling material. The space will form a dense and interconnected hole 2; when in use, when the lens body 1SS is worn on the surface 3 of the eyeball, the lens body 1 is brought into contact with the air to make the surface of the tear fluid or physiological saline (human) The tears contain considerable oxygen, and the oxygen-rich tears or physiological saline (artificial tears) will penetrate into the surface of the lens body 1 through the infiltration or wearer's blinking (ie, the eyelids will compress the lens). In the inner hole 2, it penetrates into the surface 3 of the eyeball, so that the surface of the eyeball is constantly supplemented with oxygen. Therefore, there is no eye discomfort or redness and redness in the long-term wear; The high oxygen permeability of the silicone material has the function of transporting liquid, which not only can help the sliding of the lens body 1, but also can transport nutrients and waste, and since the lens body 1 has the hole 2, it is not like the traditional silicone rubber. The lens-like effect of adsorbing 200918983 on the surface 3 of the eyeball. According to the above-mentioned silicone contact lens structure of the present invention, since the water-soluble entrapping material can be mixed with 矽], and after being molded into the lens body 1, the water-soluble chelating material is easily removed by hydrolysis, possibly There is no need to go through the plasma treatment, so there is no difficult bottleneck in the overall production, which can effectively reduce the cost of production and thus enhance the competitiveness of the product. The lens polymerization method of the present invention can be carried out by any polymerization method such as thermal polymerization or ultraviolet photopolymerization to promote polymerization. The thermal polymerization starts such as Lauroyl peroxide 5 isopropyl percarbonate, azobisisobutyronitrile, etc., which can be used to generate a free radical at a suitable high temperature to initiate polymerization. The photopolymerization initiator can be, for example, aromatic alpha-hydroxyketone, or tertiary amine plus one diketone. Additional additives may also be added to the silicone contact lens material, such as UV absorbers, pigment dyes and the like. In addition, in order to improve the contact lens process, a mold release agent, a wetting agent or the like may be added if necessary. Application Example 1 The following chemicals were uniformly mixed, and the resulting solution was identified as a chemical material I methacryloxy propyl tris (trimethyl siloxysilane (TRIS) 47 parts methyl raethacrylate (MMA) 8 parts N, N-Dimethylacrylamide (DMAA) 42 parts

Hydroxyethylmethacrylate(HEMA) 2partsHydroxyethylmethacrylate(HEMA) 2parts

Ethylene glycol dimethacrylate(EGDMA) 1.5parts 2,2'-Azobis(2,4-dimethylvaleronitrile)(ADVN) lparts 將以上的溶液倒入隱形眼鏡的模子中,然後用標準的熱聚 合方法去合成鏡片,將鏡片脫模後,浸泡在水中2小時,再保 200918983 存在生理食鹽水中,此時該鏡片雖具有淸晰的光學度’但鏡片 本身是硬的,且是疏水性的’不能作爲軟性隱形眼鏡材料。 但若以80.6%份的化學材料I和19.4%的Dow Corning 5329混合均勻的透明溶液’而使用上法所製作的鏡片’不但 具有淸晰的光學性質,並具有軟性隱形眼鏡的親水性的特質。 鏡片含水率約29%。 應用實施例2 將以下的化學物混合均勻,所形成的溶液標明爲化學材料α methacryloxy propyl tris(trimethyl siloxysilane(TRIS) 45.5 parts methyl methacrylate(MMA) 8 parts N,N-Dimethylacrylamide(DMAA) 32 parts 1,1,1,3,3,3-hexafluoroisopropyl acrylate 10.5partsEthylene glycol dimethacrylate (EGDMA) 1.5parts 2,2'-Azobis(2,4-dimethylvaleronitrile)(ADVN) lparts Pour the above solution into the mold of the contact lens, then use the standard thermal polymerization method to synthesize the lens, the lens After demolding, immersed in water for 2 hours, and then in 200918983 there is physiological saline, at this time the lens has a clear optical 'but the lens itself is hard, and is hydrophobic' can not be used as a soft contact lens material. However, if 80.6% of chemical material I and 19.4% of Dow Corning 5329 are mixed with a uniform transparent solution, the lens made by the above method not only has clear optical properties, but also has the hydrophilic nature of soft contact lenses. . The moisture content of the lens is about 29%. Application Example 2 The following chemicals were uniformly mixed, and the resulting solution was identified as a chemical substance α methacryloxy propyl tris (trimethyl siloxysilane (TRIS) 45.5 parts methyl methacrylate (MMA) 8 parts N, N-Dimethylacrylamide (DMAA) 32 parts 1 ,1,1,3,3,3-hexafluoroisopropyl acrylate 10.5parts

Ethylene glycol dimethacrylate(EGDMA) 4 parts 2,2'-Azobis(2,4-dimethylvaleronitrile)(ADVN) 2.5parts (A) 由以上的化學材料Π,使用該應用實施例1方法做出來的 隱形眼鏡片,雖具有淸晰的光學度,但鏡片本身是硬的,且是 疏水性的,不能作爲軟性隱形眼鏡的材料。 (B) 但若以4份的化學材料Π和1份的Dow Corning 5329混合 均勻的透明溶液m,而使用以上方法,所製作的鏡片,不但具 有淸晰的光學性質,並具有軟性隱形眼鏡的親水性的特質。 鏡片含水率約18%。 (C) 若以化學材料m中,可加入數滴的Blue-15配合液(1), 形成淡藍色的透明液體,而使用以上方法,所製作的軟性隱形 眼鏡片是微淡藍色的鏡片。 註:(l)Blue-15 配合液是用 Blue-15 分散於N,N-dimethyl acrylamide 的 5%液體。 (D) 若在以上的混合液(IV)中加入2.2%的 200918983 2-(4-benzoyl-3-hydroxyphenoxy) ethylacrylate,而使用以 上方法所製作的軟性隱形眼鏡片具有大於90%的UV吸收程度。 (E)製作彩色隱形眼鏡片的方法,舉例如下, 所需藍色ink是以混合適量的Blue-15於化學材料DI中, 並加入 5%量的 trimethylolpropane trimethacrylate 所形 成。Ink先在模內形成圖形,加熱後形成半成膜,再在模具中 注入化學材料皿,用上法所製成的彩色軟性隱形眼鏡片的圖形 不會脫落。 應用實施例3 將以下的化學物混合均勻,所形成的溶液標明爲化學材料V methacryloxy propyl tris(trimethyl siloxy)silane(TRIS) 46.5 parts methyl methacrylate(MMA) 8 parts N,N-Dimethylacrylamide(DMAA) 30.5 parts 1,1,1,3,3,3-hexafluoroisopropyl acrylate 10.5partsEthylene glycol dimethacrylate (EGDMA) 4 parts 2,2'-Azobis(2,4-dimethylvaleronitrile) (ADVN) 2.5parts (A) A contact lens prepared by the above method 1 using the above chemical material, Although it has a clear optical degree, the lens itself is hard and hydrophobic, and cannot be used as a material for soft contact lenses. (B) However, if 4 parts of chemical material and 1 part of Dow Corning 5329 are mixed with a uniform transparent solution m, and the above method is used, the lens produced not only has clear optical properties, but also has soft contact lenses. Hydrophilic qualities. The moisture content of the lens is about 18%. (C) If a small amount of Blue-15 complex solution (1) is added to the chemical material m, a pale blue transparent liquid is formed, and the soft contact lens produced by the above method is slightly bluish blue. lens. Note: (l) The Blue-15 complex is a 5% liquid dispersed in N,N-dimethyl acrylamide with Blue-15. (D) If 2.2% of 200918983 2-(4-benzoyl-3-hydroxyphenoxy) ethylacrylate is added to the above mixture (IV), the soft contact lenses prepared by the above method have a UV absorption of more than 90%. . (E) A method of producing a color contact lens is exemplified as follows. The desired blue ink is formed by mixing an appropriate amount of Blue-15 in a chemical material DI and adding a 5% amount of trimethylolpropane trimethacrylate. Ink first forms a pattern in the mold, forms a semi-film after heating, and then injects a chemical material dish into the mold, and the pattern of the colored soft contact lens made by the above method does not fall off. Application Example 3 The following chemicals were uniformly mixed, and the resulting solution was identified as a chemical material V methacryloxy propyl tris(trimethyl siloxy)silane(TRIS) 46.5 parts methyl methacrylate (MMA) 8 parts N, N-Dimethylacrylamide (DMAA) 30.5 Parts 1,1,1,3,3,3-hexafluoroisopropyl acrylate 10.5parts

Ethylene glycol dimethacrylate(EGDMA) 4.5 parts 2,2'-Azobis(2,4-dimethylvaleronitrile)(ADVN) 2.25parts 1,3-bis(3-methacryloxy propyl)tetrakis(trimethyl siloxy)disiloxane 1% 由以上的化學材料V,用該應用實施例1方法做出來的隱 形眼鏡片,雖具有淸晰的光學度,但鏡片本身是硬的,且是疏 水性的,不能作爲軟性隱形眼鏡的材料。 但若以4份的化學材料V和1份的Dow Corning 5329混 合均勻的透明溶液,而使用上法製作成的鏡片,不但具有淸晰 的光學性質,並具有軟性隱形眼鏡的親水性的特質。 鏡片含水率約10%。 綜合以上所述,本發明矽膠隱形眼鏡之成型方法及其結構 確可達成延長配戴使用時間、避免眼睛缺氧造成不適且降低生 200918983 產成本、提昇產品競爭力之功效,實爲一具新穎性及進步性之 發明,爰依法提出申請發明專利;惟上述說明之內容,僅爲本 發明之較佳實施例說明,舉凡依本發明之技術手段與範疇所延 伸之變化、修飾、改變或等效置換者,亦皆應落入本發明之專 利申請範圍內。 【圖式簡單說明】 第1圖係習見之隱形眼鏡結構剖面示意圖。 第2圖係本發明之成型方法流程圖。 第3圖係本發明之構造剖面圖。 【主要元件符號說明】 1.. ...鏡片本體 10....隱型眼鏡鏡片 2.. ...jim 3…眼球表面Ethylene glycol dimethacrylate (EGDMA) 4.5 parts 2,2'-Azobis(2,4-dimethylvaleronitrile)(ADVN) 2.25parts 1,3-bis(3-methacryloxy propyl)tetrakis(trimethyl siloxy)disiloxane 1% From the above chemical materials V. The contact lens prepared by the method of Application Example 1 has a clear optical degree, but the lens itself is hard and hydrophobic, and cannot be used as a material for soft contact lenses. However, if a uniform transparent solution is mixed with 4 parts of chemical material V and 1 part of Dow Corning 5329, the lens produced by the above method not only has clear optical properties, but also has the hydrophilic nature of soft contact lenses. The moisture content of the lens is about 10%. In summary, the molding method and structure of the silicone contact lens of the present invention can achieve the effect of prolonging the wearing time, avoiding the discomfort caused by hypoxia of the eye, reducing the production cost of the product 200918983, and improving the competitiveness of the product. Sexual and progressive inventions, which are filed in accordance with the law; but the above description is only for the preferred embodiments of the present invention, and variations, modifications, changes or the like which are extended by the technical means and scope of the present invention. It is also within the scope of the patent application of the present invention. [Simple description of the diagram] Fig. 1 is a schematic cross-sectional view of the contact lens structure. Figure 2 is a flow chart of the molding method of the present invention. Figure 3 is a cross-sectional view showing the structure of the present invention. [Description of main component symbols] 1.. Lens body 10....Contact lens 2.. ...jim 3... eye surface

Ref 1. Mueller et al. U.S. 4136250 2. Tanaka et al.,U.S. 4139513 3. Deichert et al. U.S. 4153641 4. Keogh et al. Q.S. 4260725 5. Harvey, III. u.S. 4711943 6.Su et al. U.S. 4740533 7. Bambury et al. U.S. 4910277 8. Mueller et al; U.S. 4983702 9. Lai et al. U.S. 5034461 10. Robertson et al· U.S. 5070169 11. Bambury et al. U. S. 5070215 12. Novicky. U.S. 5093447 13. Nandu et al. U.S. 5260000 14. Mueller et al. U.S. 5426158 15. Kunzler et al. U.S. 5710302 16 . Kunzler et al. U.S. 571*4557 17,Lai et al. U.S. 5726733 18-Kunzler et al. U.S.5908906 19.Ozark et al. U.S. 5959117 20. Vanderlaan et al. U.S. 5962548 21. Maiden et al. U.S. 6367929 22. McCabe et al. U.S. 6822016 23.Steffen et al. U.S. 6849671 200918983 24. Kunzler et al. U.S. 6891010 25. McCabe et al. U.S. 7052131 26. Novicky. U.S. 7098282 十、申請專利範圍: 1. 一種矽膠隱形眼鏡之成型方法,其至少包括: 一「混合」步驟,係將透明之矽膠基材與塡充材料相互均勻混 合爲一混合材料; 一「成型」步驟,將該混合材料成型爲一鏡片本體; 一「萃取」步驟,將該鏡片本體內之塡充材料由矽膠基材中萃 取出。 2. 如申請專利範圍第1項所述之矽膠隱形眼鏡之成型方法,其中該 「成型」步驟係利用標準的聚合方法合成該鏡片本體。 3. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係水溶性矽膠。 4. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的水溶性含矽的表面分散劑。 5. 如申請專利範圍第3項所述之砂膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的水溶性含矽的表面分散劑。 6. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的有機溶劑溶解性矽膠。 7. 如申請專利範圍第3項所述之砍膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的有機溶劑溶解性矽膠。 8. 如申請專利範圍第1或2項所述之砂膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的有機溶劑溶解性含矽的表面分散劑。 9. 如申請專利範圍第3項所述之砂膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的有機溶劑溶解性含矽的表面分散劑。 10. —種矽膠隱形眼鏡之改良結構,其係由透明之矽膠基材成型爲 一鏡片本體,於該鏡片本體表面及內部設有密集分佈且相互連通之 孔洞。 十一、圖式: 9Ref 1. Mueller et al. US 4136250 2. Tanaka et al., US 4139513 3. Deichert et al. US 4153641 4. Keogh et al. QS 4260725 5. Harvey, III. uS 4711943 6.Su et al. US 4740533 7. Bambury et al. US 4910277 8. Mueller et al; US 4983702 9. Lai et al. US 5034461 10. Robertson et al. US 5070169 11. Bambury et al. US 5070215 12. Novicky. US 5093447 13. Nandu et Al. US 5260000 14. Mueller et al. US 5426158 15. Kunzler et al. US 5710302 16 . Kunzler et al. US 571*4557 17, Lai et al. US 5726733 18-Kunzler et al. US 5908906 19. Ozark et Al. US 5959117 20. Vanderlaan et al. US 5962548 21. Maiden et al. US 6367929 22. McCabe et al. US 6822016 23. Steffen et al. US 6849671 200918983 24. Kunzler et al. US 6891010 25. McCabe et al US 7052131 26. Novicky. US 7098282 X. Patent Application Range: 1. A method for molding silicone contact lenses, comprising at least: a "mixing" step of uniformly mixing a transparent silicone substrate with a filling material Mixed material A "forming" step, the mixed material is formed into a lens body; an "extraction" step, the lens body Chen filling material removed from the extracted silicone substrate. 2. The method of forming a silicone contact lens according to claim 1, wherein the "forming" step is performed by a standard polymerization method. 3. The method of forming a silicone contact lens according to claim 1 or 2, wherein the filling material is a water-soluble silicone. 4. The method of forming a silicone contact lens according to claim 1 or 2, wherein the supplementary material is a water-soluble cerium-containing surface dispersing agent having no polymerizable group. 5. The method of forming a contact lens according to claim 3, wherein the chelating material is a water-soluble cerium-containing surface dispersing agent having no polymerizable group. 6. The method of forming a silicone contact lens according to claim 1 or 2, wherein the chelating material is a non-polymerizable organic solvent-soluble silicone. 7. The method for forming a rubberized contact lens according to claim 3, wherein the supplementary material is a polymer-free organic solvent-soluble silicone. 8. The method for molding a contact lens according to claim 1 or 2, wherein the entangled material is a non-polymerizable organic solvent-soluble surface-dispersing agent containing cerium. 9. The method for forming a contact lens according to claim 3, wherein the chelating material is a non-polymerizable organic solvent-soluble surface-dispersing agent containing cerium. 10. An improved structure of a silicone contact lens formed from a transparent silicone substrate as a lens body having densely spaced and interconnected holes in the surface and interior of the lens body. XI. Schema: 9

Claims (4)

200918983200918983 24. Kunzler et al. U.S. 689101024. Kunzler et al. U.S. 6891010 25. McCabe et al. U.S. 705213125. McCabe et al. U.S. 7052131 26. Novicky. U.S. 7098282 十、申請專利範圍: 1. 一種矽膠隱形眼鏡之成型方法,其至少包括: 一「混合」步驟,係將透明之矽膠基材與塡充材料相互均勻混 合爲一混合材料; 一「成型」步驟,將該混合材料成型爲一鏡片本體; 一「萃取」步驟,將該鏡片本體內之塡充材料由矽膠基材中萃 取出。 2. 如申請專利範圍第1項所述之矽膠隱形眼鏡之成型方法,其中該 「成型」步驟係利用標準的聚合方法合成該鏡片本體。 3. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係水溶性矽膠。 4. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的水溶性含矽的表面分散劑。 5. 如申請專利範圍第3項所述之砂膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的水溶性含矽的表面分散劑。 6. 如申請專利範圍第1或2項所述之矽膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的有機溶劑溶解性矽膠。 7. 如申請專利範圍第3項所述之砍膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的有機溶劑溶解性矽膠。 8. 如申請專利範圍第1或2項所述之砂膠隱形眼鏡之成型方法,其 中該塡充材料係無聚合基的有機溶劑溶解性含矽的表面分散劑。 9. 如申請專利範圍第3項所述之砂膠隱形眼鏡之成型方法,其中該 塡充材料係無聚合基的有機溶劑溶解性含矽的表面分散劑。 10. —種矽膠隱形眼鏡之改良結構,其係由透明之矽膠基材成型爲 一鏡片本體,於該鏡片本體表面及內部設有密集分佈且相互連通之 孔洞。 十一、圖式: 926. Novicky. US 7098282 X. Patent Application Range: 1. A method for molding silicone contact lenses, comprising at least: a "mixing" step of uniformly mixing a transparent silicone substrate and a filling material into a mixed material. And a "forming" step of forming the mixed material into a lens body; and an "extracting" step of extracting the filling material in the lens body from the silicone substrate. 2. The method of forming a silicone contact lens according to claim 1, wherein the "forming" step is performed by a standard polymerization method. 3. The method of forming a silicone contact lens according to claim 1 or 2, wherein the filling material is a water-soluble silicone. 4. The method of forming a silicone contact lens according to claim 1 or 2, wherein the supplementary material is a water-soluble cerium-containing surface dispersing agent having no polymerizable group. 5. The method of forming a contact lens according to claim 3, wherein the chelating material is a water-soluble cerium-containing surface dispersing agent having no polymerizable group. 6. The method of forming a silicone contact lens according to claim 1 or 2, wherein the chelating material is a non-polymerizable organic solvent-soluble silicone. 7. The method for forming a rubberized contact lens according to claim 3, wherein the supplementary material is a polymer-free organic solvent-soluble silicone. 8. The method for molding a contact lens according to claim 1 or 2, wherein the entangled material is a non-polymerizable organic solvent-soluble surface-dispersing agent containing cerium. 9. The method for forming a contact lens according to claim 3, wherein the chelating material is a non-polymerizable organic solvent-soluble surface-dispersing agent containing cerium. 10. An improved structure of a silicone contact lens formed from a transparent silicone substrate as a lens body having densely spaced and interconnected holes in the surface and interior of the lens body. XI. Schema: 9
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102759806A (en) * 2011-04-28 2012-10-31 星欧光学股份有限公司 Highly oxygen permeable contact lenses with voids and methods of making same
US9244200B2 (en) 2010-07-30 2016-01-26 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US11256003B2 (en) 2017-12-13 2022-02-22 Alcon Inc. Weekly and monthly disposable water gradient contact lenses

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9244200B2 (en) 2010-07-30 2016-01-26 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9411171B2 (en) 2010-07-30 2016-08-09 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US9816009B2 (en) 2010-07-30 2017-11-14 Novartis Ag Silicone hydrogel lenses with water-rich surfaces
US10781340B2 (en) 2010-07-30 2020-09-22 Alcon Inc. Silicone hydrogel lenses with water-rich surfaces
CN102759806A (en) * 2011-04-28 2012-10-31 星欧光学股份有限公司 Highly oxygen permeable contact lenses with voids and methods of making same
CN102759806B (en) * 2011-04-28 2014-04-30 星欧光学股份有限公司 Highly oxygen permeable contact lenses with voids and methods of making same
US11256003B2 (en) 2017-12-13 2022-02-22 Alcon Inc. Weekly and monthly disposable water gradient contact lenses

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