TW200909331A - An automatic distributing machine for radiopharmaceuticals - Google Patents

An automatic distributing machine for radiopharmaceuticals Download PDF

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Publication number
TW200909331A
TW200909331A TW96131171A TW96131171A TW200909331A TW 200909331 A TW200909331 A TW 200909331A TW 96131171 A TW96131171 A TW 96131171A TW 96131171 A TW96131171 A TW 96131171A TW 200909331 A TW200909331 A TW 200909331A
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Taiwan
Prior art keywords
syringe
needle
machine
injection
moving
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TW96131171A
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Chinese (zh)
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TWI319379B (en
Inventor
ming-xin Li
Wu-Zhi Lin
tian-xi Ren
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Inst Nuclear Energy Res Aec
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Priority to TW96131171A priority Critical patent/TW200909331A/en
Publication of TW200909331A publication Critical patent/TW200909331A/en
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Publication of TWI319379B publication Critical patent/TWI319379B/zh

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Abstract

An automatic racking machine for radiopharmaceuticals comprises a displacement structure on a machine that can perform three dimensional back and forth movements, a syringe rack, and a medicine bottle rack. The syringe rack provides a storage place for multiple injecting syringes; the medicine bottle rack has an up-side-down medicine bottle; the displacement structure has a syringe driving mechanism and a syringe clip base that can rotate around an horizontal axis; the syringe clip base can be driven to carry one injecting syringe and cause the injection syringe to move and insert needle into the medicine bottle; the syringe driving mechanism can move along with the syringe clip base synchronously to execute medicine extraction actions.

Description

200909331 九、發明說明: 【發明所屬之技術領域】 本發明是杨卜種核醫藥物自動分裝機,尤指—種可避免操作者直接 以手接觸放射性藥物、減少幅射曝露之情形。 【先前技術】 傳統習見之核醫藥物分裝機,大多只能應用於實驗室小型分裝,不但使 用上很不枝,且魏雜、無法稍操作,造献裝成本高昂,難以實 施大量生產之商業化行為。 有鑑於習見之核醫藥物分裝機有上述缺點,發明人乃針對該些缺點研 究改進之道,終於有本發明產生。 【發明内容】 減少操作者 疋乂本發月之主要目的在於提供一種核醫藥物自動分裝機,其可自 動w瓦裝之高継放射性核醫藥物自動充填於錢注射針筒,^ 直接曝露於幅射環境。 本發明之另-目的在於提供—種刪物自動分裝機,其亦可利駐 菌注射針筒將放射性核種分裝於其他瓶子,進行化學反應或其他用途。·,,、 本發明之又-目的在於提供—種_物自峨 抽取高毒性、高感染性藥物,具有廣泛之細值。訂適用於 為達成上述目的及功效,其所採行的技術手段包括: •樂瓶 機台,頂側至少設-承置面藥瓶,設於該機台之H 1 ,蝴機台之承置面上,其可驅動—賴持座夾持—仃 實施三維陳鍋_行,並晰-撕㈣心樞轉使^ 200909331 注射針筒可由_ 機構,可隨該斜 機構’可_針筒夾持座受移行機構之驅動而同步移行, 機構上設有—驅動桿’可連動該注射針筒執行抽藥動作。 置;一注射筒驅動 ’於該注射筒驅動200909331 IX. Description of the invention: [Technical field to which the invention pertains] The present invention relates to an automatic filling and dispensing machine for a nuclear medicine, in particular, a type in which the operator can directly contact the radioactive drug by hand and reduce the radiation exposure. [Prior Art] Most of the traditional nuclear medicine dispensing machines can only be applied to small-scale dispensing in laboratories. Not only is it not very difficult to use, but it is also difficult to operate, and the cost of manufacturing is high. It is difficult to implement mass production. Commercial behavior. In view of the above shortcomings of the nuclear medicine dispensing machine of the prior art, the inventors have studied the improvement of these shortcomings, and finally the present invention has been produced. SUMMARY OF THE INVENTION The main purpose of reducing the operator's 发本月 is to provide a nuclear medicine automatic dispensing machine, which can automatically fill the money injection syringe with the sorghum radioactive nuclear medicine automatically loaded, and directly exposed to Radiation environment. Another object of the present invention is to provide an automatic sorting and dispensing machine which can also dispense a radioactive nuclear seed into other bottles for chemical reaction or other purposes. Further, the present invention aims to provide a highly toxic and highly infectious drug with a wide range of fine values. The technical means adopted for the above purposes and functions include: • The bottle machine, at least the top side of the bottle, the H 1 set on the machine, the butterfly machine On the surface, it can be driven - depending on the holder clamping - 仃 implementation of three-dimensional Chen pot _ line, and clear - tear (four) heart pivoting ^ 200909331 injection syringe can be _ mechanism, with the oblique mechanism ' can _ syringe The clamping seat is synchronously moved by the driving mechanism, and the mechanism is provided with a driving rod that can interlock the injection syringe to perform the medicine discharging action. Set; a syringe drive ‘in the syringe drive

1 沿該水平面之X軸方向往復滑移。 —外部定位移行至可以針頭插入藥瓶之位 其中,該針筒紐座係經由—旋轉組件結合於該2_動組件上,利 用該旋轉組件之驅動,可使該針筒夾持座相對於Z軸移動組件產生轉動。 其中,該注射針筒係容置於-麟_,錄該崎敝外周緣中段向 外凸設有—環凸緣’而該針筒鱗朗於娜部位設有-凹槽,利用該凹 槽相對於環凸緣之倾橫移,而可形絲合·敵動作變化。 為使本發_上述目的、功效及舰可舰更具體的麵,茲依下列 • 附圖說明如下。 ' 【實施方式】 請參第1、2圖所示,明顯可看Α,本發明主要包括:機台丄、移行 機構2、注射筒驅動機構3、針驗4及藥絲5等部份,其中該機台1 於頂側設—承置面’移行機構2係由-X軸移動組件21、-Υ轴移動組 件2 2、-Ζ軸移動組件2 3及-旋轉組件2 4所組成,該X軸移動組件 21係直接設置於該機台!之承置面上,其係以—動力源2 2 i (可為步 200909331 進馬達)驅動—移行平台212沿一預設直線軌跡(假設為x軸)移行, Y軸移動組件2 2係設置於該移行平台2 i 2上,其係以—動力源2 2丄 (可為步進馬達)驅動-移行平台2 2 2沿_垂直㈣χ軸之水平方向直 線軌跡(假設為γ轴)移行,旋轉組件2销係設置於該移行平台2 2 2 上’其係以-動力源2 4 i驅動一旋轉座2 4 2沿一平行於該㈣之轴心 樞轉,最後,❻移動組件2 3係設置於該旋轉座2 4 2上,其係以一動 力源2 3 1㈣純㈣)3 餘該X、γ轴 方向之直線執跡(假設為2軸)移行,於該移行座2 3 2上另設有一針筒 夹持座2 3 3,且於該針筒夹持座2 3 3上設有一具開口之夹⑽3 4, 注射筒驅動機構3係結合於該移行座2 3 2上,其係以—動力源3丄(可 為步進馬達)驅動—驅動桿3 2沿-平行於Ζ軸方向之直線軌跡移行,且 使該驅動桿3 2連動一連動件3 3,於該連動件3 3底端設有-具開口之 夹槽3 4 ’咖嫩細贿觸2賴其地峨數注射 針筒4 2 ’各注射針筒4 2係容置於—料敝4工内,且於該鉛屏敝^ 外周緣t段向外凸設有一環凸緣4 i上,而於該針筒㈣底側設有複數注 射針套管分別對應於各注射針筒4 2之注射針位置,使各注射針筒4 2置 於該針筒架4上賴時,各注射針套管可分別套合於各注射針外周側,藥 瓶架5係設置於移行觀、針陶旁侧,主要係供放置裝有核醫藥物 的藥瓶,且該藥瓶係放置於專用舞51内_ ,且使藥瓶瓶口朝下,以 便利抽藥。 連結之數位 再°月參第2、3® ’可知操作時’該移行機構2係藉由- 200909331 化系統控制而可使x轴移動紐件21、、移触件 2 3分別移行適當距離,並驅使該·夾持座2 3 3之·/移動組件 該_4 1之環凸緣4 1 1 ’而注射筒驅動機構3之夾挿3 == 於注射购之抽藥桿;然後2軸移動組件:= 使錯屏敝41、注射針筒42脫離針上昇, γ軸移動組件2 2驅動該注射針筒4 碰紋轴移動組件2 1、 w行輯,該旋轉組件2 4驅動 ::°=下方’ 再上…時,組件2 3之移行座… 3之驅奸3 22之謂針可獻藥瓶内,再彻注難驅動機構 =之《才干32驅動連動件33,使其央槽以帶動注射針筒Μ之抽率 杯開始由藥瓶内抽取核醫藥物; ’、 3 2 =主2完成馳序之後,Z_組件2 3之移行座2 2丄,靖針筒4 2之注射針向下脫離藥瓶,然後,X軸移動組件 轴移動級件2 2驅動該注射針筒4 2移行至針筒架4上方,且於 該旋触件2 4驅動該注射針筒4 2再轉1 8 0度,使注 使注射針ηΓ射針朝下’再使❻移触件2 3之移行座2 3 2下降, 三2置於針筒架4内之定位,且以其注射針伸入注射針套管 紐2完成-藥物分裝程序;同時,可持續重覆上述各步驟,以執行對 〇 3 ^4上其它注射針筒4 2之抽藥作業。 彳述,本發明之核醫藥物自動分裝機確可達成避免操作者接 觸放射性藥物、物刪權,實為—騎雛及進步性之發明, 200909331 依法提出申請發明桃惟上魏明之内容,僅為本發明之較佳實施例說 明,舉凡依本發明之技術手段與範輕延狀變化、修飾、改變或等效置 換者,亦皆應落入本發明之專利申請範圍内。 【圖式簡單說明】 第一圖係本發明之構造分解圖。 第二圖係本發明之整體組合外觀及其操作動作圖(一)。 第三圖係本發明之操作動作圖(二)。 【主要元件符號說明】 11— X軸移動組件 13— Z軸移動組件 2.....移行機構 211、221、23卜如、31...動力源 22· · _. Y軸移動組件 232.. .移行座 ' 234、34. ·.夾槽 242.. .旋轉座 32.. ..驅動桿 4 .....針筒架 411.. .環凸緣 5 .....藥瓶架 1.....機台 12· · · · Y軸移動組件 14----旋轉組件 21· · ·. X軸移動組件 212'222··.移行平台 23 ----2輪移動組件 233...針筒夾持座 24 ----旋轉級件 3.....注射筒驅動機構 33----連動件 41.··.鉛屏敝 42—注射針筒 51—鉛罐 91 Reciprocating slip along the X-axis direction of the horizontal plane. - external positioning is moved to a position in which the needle can be inserted into the vial, the syringe hub being coupled to the 2 - moving assembly via a rotating assembly, with which the syringe holder can be positioned relative to The Z-axis moving assembly produces a rotation. Wherein, the injection syringe is placed in the -lin_, and the middle portion of the rugged outer circumference is convexly provided with a ring flange, and the cylinder is provided with a groove, and the groove is used. With respect to the slanting of the ring flange, the shape and the action of the enemy are changed. In order to make the above-mentioned purpose, function and ship's ship more specific, the following figures are as follows. [Embodiment] Please refer to Figures 1 and 2 for obvious observation. The present invention mainly includes: a machine sill, a moving mechanism 2, a syringe driving mechanism 3, a needle test 4, and a medicinal wire 5, etc. Wherein the machine 1 is disposed on the top side - the bearing surface 'moving mechanism 2 is composed of an -X axis moving component 21, a Υ axis moving component 2 2, a Ζ axis moving component 23 and a rotating component 24, The X-axis moving component 21 is directly disposed on the machine! On the mounting surface, it is driven by a power source 2 2 i (which can be stepped into the motor 200909331). The transition platform 212 moves along a predetermined linear path (assumed to be an x-axis), and the Y-axis moving component 2 2 is set. On the transition platform 2 i 2, it is driven by a power source 2 2 丄 (which can be a stepping motor)-moving platform 2 2 2 along a horizontal straight track of the _ vertical (four) χ axis (assumed to be a γ axis), The rotating component 2 is disposed on the moving platform 2 2 2 and is driven by a power source 2 4 i to rotate a rotating seat 2 4 2 along an axis parallel to the (4), and finally, the moving component 2 3 The system is disposed on the rotating base 224, and is moved by a power source 2 3 1 (four) pure (four)) 3 lines in the X and γ axis directions (assumed to be 2 axes), and the moving seat 2 3 2 A syringe holder 2 3 3 is further disposed, and an opening clamp (10) 34 is disposed on the syringe holder 2 3 3 , and the syringe driving mechanism 3 is coupled to the transition seat 23 2 , It is driven by a power source 3 丄 (which can be a stepping motor) - the drive rod 3 2 moves along a linear trajectory parallel to the Ζ axis direction, and the drive rod 3 2 is linked a linkage member 3 3 is provided at the bottom end of the linkage member 3 3 - a slot with an opening 3 4 'Chan tender bribes 2 其 峨 number of injection syringes 4 2 'injection syringes 4 2 Placed in the material magazine 4, and a ring flange 4 i is protruded outwardly from the outer peripheral edge t of the lead screen, and a plurality of injection needle sleeves are respectively arranged on the bottom side of the syringe (four) respectively. The position of the injection needle of each of the injection syringes 4 2 is such that when the injection syringes 4 2 are placed on the syringe holder 4, the injection needle sleeves can be respectively fitted to the outer peripheral sides of the injection needles, and the vial holder 5 is attached. It is set on the side of the shifting line and the side of the needle pottery. It is mainly used to place the medicine bottle containing the nuclear medicine, and the medicine bottle is placed in the special dance 51, and the bottle mouth is made downward to facilitate the medicine. The digits of the connection are again in the second and third quarters, and the movement mechanism 2 can control the x-axis moving button 21 and the moving member 2 to move by an appropriate distance by the control system of 200909331. And driving the holder 2 3 3 / / moving the assembly _ 4 1 ring flange 4 1 1 ' and the syringe drive mechanism 3 is inserted 3 = = the injection rod is purchased; then 2 axes Moving the component: = the wrong screen 41, the syringe cylinder 42 is lifted off the needle, and the gamma axis moving assembly 2 2 drives the syringe barrel 4 the rubbing axis moving assembly 2 1 , w line series, the rotating assembly 24 drive: °=Bottom' again... When the component 2 3 moves the seat... 3 The rapper 3 22 The needle can be placed in the medicine bottle, and then the hard drive mechanism = "The 32 drive linkage 33, so that it The trough starts to extract the nuclear medicine from the medicine bottle by driving the suction cup of the injection syringe; ', 3 2 = after the main 2 completes the suspension, the Z_component 2 3 moves the seat 2 2丄, the Jing syringe 4 2 The injection needle is disengaged from the vial, and then the X-axis moving assembly shaft moving step 2 2 drives the syringe 4 2 to move over the syringe holder 4, and the needle is driven by the screw member 24 The cylinder 4 2 is further rotated by 180 degrees so that the injection needle η Γ the needle is turned downwards, and then the shifting seat 2 3 2 of the ❻ moving contact piece 2 3 is lowered, and the third 2 is placed in the position of the syringe holder 4, and The injection-needle is inserted into the needle casing 2 to complete the drug dispensing procedure; at the same time, the above steps can be repeated repeatedly to perform the sampling operation of the other syringes 4 on the 〇3^4. As described above, the automatic dispensing machine for nuclear medicine of the present invention can achieve the avoidance of the operator's exposure to radioactive drugs and the deletion of rights, and is actually an invention of riding and progressive, 200909331, and filed an application for the invention of the contents of Tao Weiwei Wei Ming, only It is to be understood that the preferred embodiments of the present invention are intended to be within the scope of the appended claims. BRIEF DESCRIPTION OF THE DRAWINGS The first figure is an exploded view of the structure of the present invention. The second figure is the overall combined appearance of the present invention and its operational action diagram (1). The third figure is the operation action diagram (2) of the present invention. [Description of main component symbols] 11 - X-axis moving component 13 - Z-axis moving component 2..... Moving mechanism 211, 221, 23 Bu, 31... Power source 22 · · _. Y-axis moving component 232 .. .moving seat ' 234, 34. ·. Clamping groove 242.. . Rotating seat 32.. .. drive rod 4 ..... syringe holder 411.. ring flange 5 ..... medicine Bottle holder 1.....machine 12···· Y-axis moving assembly 14----rotating assembly 21···. X-axis moving assembly 212'222··. moving platform 23 ----2 round Moving assembly 233... syringe holder 24 - rotating stage member 3... syringe drive mechanism 33----linking member 41..·. lead screen 42-injection syringe 51 - lead cans 9

Claims (1)

200909331 十、申請專利範圍: 1· 一種核醫藥物自動分裝機,其至少包括: -機台’頂側至少設-承置面;—藥瓶,設於該機台之—旁側一移 行機構,設於該機台之承置面上,其可驅動一針筒失持座爽持—注射針 筒,以實施繼間之各方向往復移行,並沿其中—水平方向為軸心枢轉 使該注射針筒可由-外部定位移行至可以針頭插人藥瓶之位置卜注射筒 驅動機構’可隨該針筒夾持座受移行機構之鶴而同步移行,_注射筒 驅動機構上設有-驅動桿,可連動該注射針筒執行抽藥動作。 2.如申請專利範圍第1項所述之核醫藥物自動分裝機,其中該移行機構至 少係由一X歸動組件…以鶴組件及-❻移動組件所組成,紗 針筒夹持越受該ζι«動組件驅動而可沿—垂直之z齡向昇降,% 軸移動組侧密軸移触件驅動而沿—預設水平面γ軸方向往復滑 移,且該丫綱咐_齡細^晴㈣ 復滑移。 -驅動,可 3·如申請專糊第2項所物編自_機,㈣針筒爽持座 係經由-旋轉組件結合於該ζ軸移動組件上,利用該旋轉組件之肩 使該針筒續鍊對於2_触件產生轉動。 =申請專利細第!或2或3項所述之郷騎自動分裝機, 口之移行機構旁側設有—針驗,可供放置注射針筒。 其中該機 =申請專利朗第4項所述之核醫難自動分顧,射該針筒架底側 .定位時,分別套 叹有至-注射針套管,可於各注射針筒置於該針筒架上 合於各注射針外周侧。 200909331 6.如申請專利範圍第!或2或3項所述之核卿 射針筒係容置於-轉_ 〃 4機’其中觀 也 且於该錯屏敵外周緣中段向外凸讯右„ 緣’而該針筒夾持座則於相對 凸叹有1凸 之往㈣欽 有—凹槽,利用該凹槽相對於環凸续 之在復k移,而可形成套合或鬆脫之動作變化。 衣凸緣 2如申請專利細第4項所述之核醫藥物自動分裝機,其中該注 令置於-錯屏敝内,且於該_外周緣中段向外 = ==相對―槽,利一對於二 移而可开)成套合或鬆脫之動作變化。 、 8.如申請專利細第5項所述之核„物自齡裝機,射該注射針筒传 谷置於i屏敝内,且於該轉敝相緣中段向外凸設有—環凸緣,的 針筒夹持座職娜倾有—纷· _树於環嫩往復橫移, 而可形成套合或鬆脫之動作變化。 1如申請專利範圍第丄或2或3項所述之核醫藥物自動分裝機,其中該藥 瓶係設置於一藥瓶架上,且使其瓶口朝下。 10·如申請專利範圍第9項所述之核醫藥物自動分裝機,其中該藥瓶係容 置於一錯罐内。200909331 X. Patent application scope: 1. A nuclear medicine automatic filling machine, which at least includes: - at least the top surface of the machine 'the top side - the receiving surface; - the medicine bottle, which is arranged on the machine side - a side moving mechanism It is arranged on the bearing surface of the machine, which can drive a syringe to hold the needle-injection syringe to perform the reciprocating movement in all directions, and pivot along the horizontal direction thereof. The syringe can be moved from the external position to the position where the needle can be inserted into the vial. The syringe drive mechanism can be moved synchronously with the crane of the syringe holder. The syringe drive mechanism is provided with - The driving rod can be linked to the injection cylinder to perform a pumping action. 2. The nuclear medicine automatic dispensing machine according to claim 1, wherein the moving mechanism is composed of at least an X-returning component, a crane component and a ❻ moving component, and the yarn cylinder is clamped more Ζι« moving component drive can be moved up and down along the vertical z-age, the %-axis moving group side is driven by the close-axis moving member and reciprocally slides along the γ-axis direction of the preset horizontal plane, and the 丫 咐 咐 _ _ _ _ _ (iv) Complex slip. - drive, can be 3, if the application of the special paste item 2 is programmed from the machine, (4) the syringe holder is coupled to the shaft moving assembly via the rotating component, and the syringe is made by the shoulder of the rotating component The chain continues to rotate for the 2_contact. = Apply for a patent fine! Or the automatic loading and unloading machine mentioned in 2 or 3, the side of the moving mechanism is provided with a needle test for placing the injection syringe. Among them, the machine = the application of the patent lang 4th, the nuclear medicine is automatically divided, and the bottom side of the syringe frame is shot. When positioning, respectively, the sneezing-injection needle sleeve can be placed in each injection syringe. The syringe holder is attached to the outer peripheral side of each injection needle. 200909331 6. If you apply for a patent scope! Or the nuclear injection needle cylinder described in item 2 or 3 is placed in the -turn _ 〃 4 machine, and the cylinder is clamped to the right side of the outer circumference of the wrong screen and the needle is clamped. The seat has a convex (s) convex groove in the opposite sigh, and the groove is continuously moved with respect to the ring convex, and the movement of the fitting or loosening can be formed. The nuclear medicine automatic dispensing machine according to the fourth aspect of the invention, wherein the injection order is placed in the wrong screen, and the middle portion of the outer circumference is outward ===relative to the slot, and the profit is for the second shift. The movement of the set or the looseness of the set can be opened. 8. The nuclear device according to the fifth item of the patent application, the shotgun is placed in the screen, and the turn is The middle part of the 敝 phase is convexly provided with a ring flange, and the needle holder is held by the needle. The tree _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ [1] The nuclear medicine automatic dispensing machine of claim 2 or 2 or 3, wherein the vial is disposed on a vial rack with the bottle mouth facing downward. 10. The nuclear medicine automatic dispensing machine according to claim 9, wherein the medicine bottle is placed in a wrong tank.
TW96131171A 2007-08-23 2007-08-23 An automatic distributing machine for radiopharmaceuticals TW200909331A (en)

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Application Number Priority Date Filing Date Title
TW96131171A TW200909331A (en) 2007-08-23 2007-08-23 An automatic distributing machine for radiopharmaceuticals

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TWI319379B TWI319379B (en) 2010-01-11

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