200843707 九、發明說明： 【發明所屬之技術領域】 二彈性鉸接件。 本餐明係關於调節人工水晶體的第 【先前技術】200843707 IX. Description of the invention: [Technical field to which the invention pertains] Two elastic hinges. This meal is the first to adjust artificial hydrocrystals. [Prior Art]
多年來人工水晶體具有附接有環圈以使水晶體對中且 使水晶體固㈣人類眼睛之空囊袋中的單—光學部設計。 在年代中期引進了板式水晶體’其包含長度1〇5_、 具有6 mm光學部的石夕樹脂水晶體。此等水晶體可摺疊， 但無法很好地固著於壹岱φ古M i U者於曩衣中，而停留在前囊與後囊之間的 袋子中。最初的可摺疊水晶體全部由矽樹脂製成。在2〇 世紀90彳代中期，引入一種丙烯酸材料作為水晶體之光 车W丙烯馱水θ曰體包含具有直角邊緣的雙凸面光學部， 環圈係插入該光學部以使水晶體在眼中對中且使其固著在 囊袋内。 近來，言周節性人工水晶體已被引進市場，其通常為經 改進的板式接觸水晶體（plate haptic lenses)。板式接觸 水晶體可稱為具有兩個或兩個以上結合於光學部的密著板 之人工水晶體。 可撓性的丙烯酸材料在眼科的外科醫生間獲得顯著的 晋及性’然而某些丙烯酸材料無法在不破裂的情況下多次 屈曲。在2003年，超過50%之植入的人工水晶體具有丙 烯酸光學部。亦已引進了可撓性水凝膠及科拉默 (collamer )水晶體。 200843707 晶體二::屈曲沿著眼睛軸線移動而起作用的調節性水 料。由 某種程度上限制了可用來製造水晶體的材 ”現Γ 可撓性且可以.彎曲大概數百萬次而不 二：出任何損傷’因此其為理想的材料 為水晶體設計的一部分而放置成跨過鄰近= 。勺板件’用以促進光學部相對於密著板的末端移動。For many years, artificial crystals have a single-optical design with an annulus attached to the ring to center the crystallites and solidify the crystals into the empty pockets of the human eye. In the middle of the chronology, a plate crystal was introduced which contained a length of 1〇5_, a stone crystal with a 6 mm optical portion. These crystals are foldable, but are not well fixed in the 壹岱 古 古 M i U in the sputum, and stay in the bag between the anterior and posterior capsules. The original collapsible crystals were all made of silicone resin. In the middle of the 1990s, an acrylic material was introduced as a light vehicle. The propylene water θ 曰 body includes a biconvex optic having a right-angled edge, and the ring is inserted into the optical portion to center the crystal in the eye and It is fixed in the pouch. Recently, pericardial artificial crystals have been introduced to the market, which are usually improved plate haptic lenses. The plate contact crystal can be referred to as an artificial crystal having two or more of the adhesion plates bonded to the optical portion. Flexible acrylic materials achieve significant advancement among ophthalmic surgeons' However, some acrylic materials cannot be flexed multiple times without breaking. In 2003, more than 50% of implanted artificial crystals had an acrylic optical section. Flexible hydrogels and collamer crystals have also been introduced. 200843707 Crystal 2:: Regulating water that acts to flex along the axis of the eye. To some extent, the materials that can be used to make crystals are now "flexible and can bend. Millions of times instead of any damage" so it is ideal for materials that are part of the crystal design. Across the adjacent =. The scoop plate' is used to promote the movement of the optics relative to the end of the clad plate.
【發明内容】 月13日提出申請之序號 ’此申請案的揭露内容係以參 案的交g I昭 本發明主張2007年 ⑼/894’631申請案的優先權 考的方式加入本文之中。 一根據本發明的較佳實命卜一種調節性水晶冑包含具有 一個帶有-個可撓性固體光學部的水晶體，兩個或兩個以 上的擴展部分係接附於該光學部。擴展部分、密著件、可 為圖1、圖2、圖8之板件或圖4、圖5、圖6、圖7及圖 =可為開放式或閉合式的環圈，每—者均能夠在不破裂 =況下屈曲多次。密著件較佳在其遠端具有固著及對中 ::斂’例如正面或背面-側或兩側上之突起。擴展部分經 十以使得在睫狀肌收縮及與之相關的玻璃體腔壓力增加 1，擴展部分係被建構成能夠藉由滑入囊袋凹穴中而在周 适或向外移動。此可伴隨有使密著件之近端比遠端窄、或 伴Ik有使该等密著件具有平行側面。睫狀肌收縮時，該水 晶體設計隨著玻璃體腔壓力增加在周邊移動或前部移動。 7 200843707 跨過鄰近於光學部之擴展#八μ >, 1之擴展邛分的鉸接件或溝槽促進光學部 相對於擴展部分之古# ΛΛ # β ^ ^ 1 ，…二I: 可撓性鉸接件之寬基座允 。、乂接件之料基麵著睫狀肌收縮及玻璃體腔 沿水晶體之縱轴拉伸，因此除水晶體光學部與密著件：間 m化而弓丨起的在後部成㈣曲之光學於 "、者件之外端的前部移動之外，允許光學部相對於密著件 之兩端的前部移動。 對於人類來說，當睫狀肌收縮時整個水晶體向前移動， 调卽性水晶體亦然。在睫狀肌收縮期間，玻璃體魔力择加 且此可以彈性鉸接件使可撓性水晶體之光 件之兩端向前移動。 卞於山者 此外’隨著睫狀肌收縮及小帶鬆他，水晶體之周朴 :拉力減小’且纖維化囊袋可隨後對水晶體施加中心徑向 縱向力’此可致使光學部形狀改變，從而除光學部移動之 外其增加眼屈光改變之能力。此可藉由密著件變形或藉由 光學部中心之厚度隨著其曲率半徑減小增加而發生。胃 因此’睫狀肌收縮時調節性肌之調節能力 因素之組合，即： iu a)像是人類晶狀體中所發生之整個水晶體之前部移 動。 ^ b)玻璃體腔壓力增加，其致使在眼中後部成棋頂狀之 密著件在周邊移動，藉此允許後部成拱頂狀之水晶體光㉟ 部改變其與密著件之間的角度，且相對於密著件之外端= 别移動。 200843707 C)鉸接件之彈性基座拉伸而引起的光學部相對於 件之外端與内端之前部移動。 山 d)薄水晶體光學部之變形。 各種機制可單獨或結合起來起作用，且主要取決μ 著件之設計。密著件可為板狀或環圈設計，且環圈可為^ 放式或閉合式。較佳設計為板件。板在前部或後部或二者 表面上可具有突出。SUMMARY OF THE INVENTION The serial number of the application filed on the 13th of the month is disclosed in the present application. A preferred crystal according to the present invention comprises a crystal lens having a flexible solid optical portion, and two or more extensions are attached to the optical portion. The extension part, the adhesion part, the board piece of Fig. 1, Fig. 2, Fig. 8 or Fig. 4, Fig. 5, Fig. 6, Fig. 7 and Fig. = can be an open or closed ring, each of which Can flex more than once without breaking. Preferably, the adhesive member has a projection on its distal end that is affixed and centered, e.g., on the front or back side or on either side. The extension is extended so that the contraction of the ciliary muscle and the associated vitreous cavity pressure increase. The expanded portion is constructed to be able to move circumferentially or outwardly by sliding into the pocket of the pocket. This may be accompanied by having the proximal end of the adhesive member narrower than the distal end, or with Ik having the adhesive members having parallel sides. When the ciliary muscle contracts, the crystal design moves around the front or moves forward as the vitreous cavity pressure increases. 7 200843707 Across the extension of the optics section #八μ >, the extension of the hinge of the hinge or the groove promotes the optics relative to the extension of the ancient # ΛΛ # β ^ ^ 1 ,... II I: flexible The wide base of the hinges allows. The base of the splicing joint is contracted by the ciliary muscle and the vitreous cavity is stretched along the longitudinal axis of the crystal. Therefore, the optics of the crystal and the adhesive are removed. ", in addition to the front movement of the outer end of the member, allows the optical portion to move relative to the front of both ends of the adhesive member. For humans, when the ciliary muscle contracts, the entire crystal of the crystal moves forward, as does the turbid crystal. During the contraction of the ciliary muscle, the vitreous magic is added and this allows the elastic hinge to move the ends of the flexible member of the flexible lens forward. In addition to the mountain, in addition to the contraction of the ciliary muscle and the loosening of the small band, the circumference of the crystal is reduced: the tension is reduced and the fibrotic pocket can then apply a central radial longitudinal force to the crystal. This can cause the shape of the optic to change. In addition to the movement of the optics, it increases the ability of the eye to change its refractive power. This can occur by deformation of the adhesive or by an increase in the thickness of the center of the optic as its radius of curvature decreases. The stomach thus combines the ability of the regulatory muscles to regulate the contraction of the ciliary muscle, ie: iu a) like the movement of the entire front of the crystal that occurs in the human lens. ^ b) an increase in the vitreous cavity pressure, which causes the adhesion of the posterior portion in the eye to move around in the periphery, thereby allowing the rear dome-shaped crystal light 35 to change its angle with the adhesive member, and Relative to the outer end of the adhesive member = do not move. 200843707 C) The optical portion caused by the elastic base of the hinge is moved relative to the outer end of the member and the front end of the inner end. Mountain d) Deformation of the optical part of the thin hydrocrystal. The various mechanisms can work individually or in combination, and are primarily dependent on the design of the μ. The adhesive member can be a plate or a ring, and the ring can be either closed or closed. It is preferably designed as a plate. The panels may have protrusions on the front or back or both surfaces.
在一些具體實例中，密著件的側面為平行的，藉此允 =其在睫狀肌收縮且小帶鬆弛時沿囊袋凹穴滑動。玻璃體 [力推動IOL ’藉此使在後部成拱頂狀之水晶體平坦化而 ，光學部相對於㈣件之外端向前移動。接著具有鬆弛小 ▼之袋沿水晶體之長軸變形。 當板密著件之遠端比近端寬時，此提供囊袋凹穴與板 之較寬接觸面冑’且使水晶體敎以提供更可預測之遠距 視力。當鄰近於光學部之窄近端具有鉸接件時，其提供較 ^抗性的鉸接件基$。介於鉸接件兩壁之間的鉸接件基座 車乂乜經加寬以允許其如彈性帶般拉伸。由於板之窄部分移 入車乂見凹穴中，因此板之形狀允許板較易於在周邊移動。 =於在、著件本身具有可撓性及彈性，其亦可拉伸以允許光 予部之額外前部移動。此亦可在無需鉸接件的情況下發 生。 因此，本發明之特徵係提供改良形式之調節性水晶體 【實施方式】 9 200843707 兄4有圖1，詳細地說明較佳具體實例，其包含形成 為二下各物之人工水晶體1 :較佳由矽樹脂製成的可撓性 α心光學部2，及任何適當形式之可撓性擴展部分4，但 杈佳為具有鄰近於光學部之窄基座之矽樹脂三角板密著 件，其能夠在無損傷的情況下多次彎曲。光學部2及密著 二^較佳在植入眼中之前為同平面的，且兩個或兩個以上 在者件4自光學部2向遠側擴展。密著件可為板件或環圈， 其可為開放式或閉合式的。可在鉸接之密著件4的遠端提 供如圖6所示之固著及對中爪鉤或如圖9至圖1 1所示之 環圈或突起。 …水晶體自環尖至環尖之典型長度為1〇 〇_12 5〇_，且 光學部2通常為4.5_7.G _直徑的光學部。密著件板長度 較佳為10.0-H.5 _。爪鉤6較佳為約5 〇職寬且包含 四點固著環圈’該環圈在將水晶體置於囊袋或放入任意插 入筒中時彎曲。四點固著環圈之兩個末端8具有略微不同 的構造且有助於以鉸接件處於適當位置指示外科醫生水晶 體正確側面朝上。 重要地，密著件4具有三角形，其鄰近於光學部較宽 且在外端較寬。在密著件4與光學部2之外周之間提供鉸 接件ίο,且尤其需要具有肖光學部相切之窄鉸接件寬度u 之寬彈性基座12 (圖3)以進—步允許光學部2因薄彈性 鉸接件基座隨著玻璃體腔壓力增加拉伸而更多地向前移 動丄其允許與諸如美國專利帛6,398，126號中所展示者之 當前設計相比光學部更多的前部移動。典型鉸接件寬度u 10 200843707 為 5·〇 _ ’且較佳具有縱向如箭頭12指示之0.06-0.4 匪，且較佳⑽随的鉸接件基座寬度（如圖3所見）。 基座12之厚度14起、佔i 為0·5-1·5 mm。較寬鉸接件基座12 如彈性帶般拉伸促進光學部2之更大的前部移動。 /又接件1(M立於所植入水晶體之前側，且如目工所見右 側％圈6之圓形末端8指示錢接件處於最高處。末端8為 □心的而對面％圈之末端為印形的。較寬環圈6及寬周邊 板使水晶體穩定且因此提供較佳及更可預測之遠距視力。 較佳地光學部及板密著件為矽樹脂且環6為聚醯亞 胺。 在光予。卩2之後部表面周圍可存在尖銳的度邊緣 乂減^手術後細胞跨過水晶體後囊之遷移且藉此降低 後囊渾濁的發生率及YAG後部水晶體囊切開術之必要性。 亦可存在-個或多個如《 !及圖2所見的跨過板以進一步 防止後囊軍濁之脊狀物16。光學部可具有—或兩個為多球 面、非球面或菲涅耳鏡面（FresneU)之表面。 圖4到圖12說明具有不同密著件及固著裝置之變型。 如所示之鉸接# 10可位於板密著件之一側或兩側，或位 於環圈密著件之侧面上。 如在此項技術中所熟知，移除天然水晶體後將諸如圖 式中所示者之人工水晶冑"直入眼之囊袋中。穿過角膜或 革膜中之小開口後，經由人類水晶體之前囊袋中所裂開之 通常為圓㈣開口將水晶體插入囊袋中。將密著件4或广 6之外端定位於囊袋之盲* (cul_de_sac)巾。密著件或二 11 200843707 之外端與袋盲管緊密接近，且環偏離中心以符合囊袋之内 表面。在環® 6之外端部分上提供環之末端或結用於固著 以經纖維化將水晶體緊固於囊袋或盲管中，纖維化係在外 科手術移除中心水晶體皮質及核後在囊袋中進行。 ί 環圈6之内端可由與密著件4相同的材料整體式形成， 或環圈可為諸如聚醯亞胺之獨立材料。若環圈係由獨立材 料形成，則將其模製於密著件4之末端部分中或若水晶體 經車床切割，則在製造水晶體主體後連接環圈。 因此，已展示且描述理想地包含有石夕樹脂光學部及石夕 樹脂密著板的水晶體’該矽樹脂密著板在其遠端具有環 圈，環圈可為不同於板件之材料且提供水晶體在眼中的固 著及對中作用。密著件娘呀士+ 、—又汁以在中心及後部沿著藉由人 另員展袋之前囊及後囊的炫合而形成的管道移動。具有可产 者水晶體縱軸如同橡皮筋般拉伸之寬彈性欽接件基座 晶體係允許光學料以藉錢接件之屈曲及其寬彈 之拉伸而移動。 厂 在連同所附圖式及申請專利範圍一起研究本說明書之 後，本發明之各種改轡、 改進、修改及其他用途及應用對 无、省此項技術者而言將e 發明…… 而易見的。本申請案未偏離本 :由之知神及範圍的所有改變、改進、修改及其他用途是 要由以下的申請專利範圍所涵蓋。 疋 【圖式簡單說明】 圖1為本發明之較佳呈 平乂1土具體貫例的前視圖 12 200843707 圖2為側視圖。 3為具有加寬鉸接件基座之鉸接件的詳細視圖 回4到圖12展示密著件之變型。 根據本發明，出m ^ & 浠酸、科拉丄f學部為可摺疊、可撓性㈣樹腊、丙 次摺膠材料，且密著板件為將能夠承受多 且，又有知傷的可摺疊材料，例如石夕樹脂、水 =默材料。較佳地’密著板件的末端基本上具有;= 者衣置且可鉸接至光學部。 开夕固 【主要元件符號說明】 1 :人工水晶體 2 :光學部 4 :可撓性擴展部分/密著件 6 ·爪釣/環 8 :末端 I 〇 :鉸接件 II :鉸接件寬度 12 ·基座 13 :銳360度邊緣 14 :厚度 1 6 :脊狀物 13In some embodiments, the sides of the adherent are parallel, thereby allowing it to slide along the pocket of the pocket as the ciliary muscle contracts and the zonule relaxes. The glass body [force pushes the IOL" thereby flattening the rear dome-shaped crystal, and the optical portion moves forward relative to the outer end of the (four) member. Then the bag with a small slack is deformed along the long axis of the crystal. When the distal end of the plate-adherent member is wider than the proximal end, this provides a wider contact surface of the pocket pocket to the plate' and allows the lens to collapse to provide a more predictable distance vision. It provides a more resistant hinge base $ when it has a hinge adjacent the narrow proximal end of the optic. The hinge base Between the two walls of the hinge is widened to allow it to stretch as an elastic band. Since the narrow portion of the panel is moved into the rim, the shape of the panel allows the panel to be easily moved around. The member itself is flexible and elastic, and it can also be stretched to allow additional front movement of the light portion. This can also occur without the need for a hinge. Accordingly, the features of the present invention provide an improved form of accommodating crystal [Embodiment] 9 200843707 Brother 4 has Figure 1, which illustrates in detail a preferred embodiment comprising an artificial crystal 1 formed as a separate material: preferably by a flexible alpha core optic 2 made of a resin, and any suitable form of flexible extension 4, but preferably a resinous triangular plate adhesive having a narrow base adjacent to the optical portion, which is capable of Bending multiple times without damage. The optics 2 and the adhesive are preferably coplanar prior to implantation in the eye, and two or more of the members 4 extend distally from the optic 2 . The adhesive member can be a plate or a ring, which can be open or closed. A fixing and centering claw hook as shown in Fig. 6 or a loop or projection as shown in Figs. 9 to 11 can be provided at the distal end of the hinged adhesive member 4. The typical length of the crystal from the tip of the ring to the tip of the ring is 1〇 12_12 5〇_, and the optical portion 2 is usually an optical portion of 4.5_7.G _ diameter. The length of the adhesion plate is preferably 10.0-H.5 _. The claw hook 6 is preferably about 5 inches wide and includes a four-point fixation loop. The loop bends when the crystal is placed in the pouch or placed in any insertion barrel. The two ends 8 of the four-point fixation loop have a slightly different configuration and help to position the surgeon in the proper position with the hinges in place. Importantly, the adhesive member 4 has a triangular shape which is wider adjacent to the optical portion and wider at the outer end. A hinge ίο is provided between the adhesive member 4 and the outer periphery of the optical portion 2, and in particular, a wide elastic base 12 (Fig. 3) having a narrow hinge width u tangent to the chol optic portion is required to further allow the optical portion 2 because the thin elastic hinge base is more moved forward as the vitreous cavity pressure is increased, which allows for more front of the optics than the current design of those shown in U.S. Patent No. 6,398,126. Department moves. A typical hinge width u 10 200843707 is 5·〇 _ ' and preferably has a longitudinal direction of 0.06-0.4 指示 as indicated by arrow 12, and preferably (10) a hinge base width (as seen in Figure 3). The thickness of the susceptor 12 is 14 and accounts for 0·5-1·5 mm. The wider hinge base 12 stretches as the elastic band promotes greater front movement of the optic 2. / again connector 1 (M stands on the front side of the implanted crystal, and as seen by the eye, the rounded end 8 of the right side of the ring 6 indicates that the money connector is at the highest position. The end 8 is the center of the circle and the end of the % circle The wider ring 6 and the wide peripheral plate stabilize the crystallite and thus provide better and more predictable distance vision. Preferably, the optic and plate seals are silicone and the ring 6 is poly. Imine. There may be a sharp edge around the surface of the light after the 卩2 乂2 reduction ^ migration of the cells after the operation of the posterior capsule, and thereby reducing the incidence of posterior capsule opacity and YAG posterior capsular capsular Necessity. There may also be one or more ridges 16 that cross the plate as seen in Figure 2 and further prevent the back pocket from turbid. The optics may have - or two are multi-spherical, aspheric or The surface of the Fresnel mirror (FresneU). Figures 4 to 12 illustrate variations with different adhesives and fixtures. The hinge #10 as shown may be located on one or both sides of the panel seal or on On the side of the ring-shaped adhesive member. Natural crystals are removed as is well known in the art. Inserting an artificial crystal such as the one shown in the figure into the pocket of the eye. After passing through a small opening in the cornea or leather, the usually round (four) opening that is split through the capsule in front of the human crystal will The crystal is inserted into the capsular bag. The outer end of the adhesive member 4 or the wide 6 is positioned in the cul_de_sac towel of the capsular bag. The outer part of the adhesive member or the second 11 200843707 is close to the bag blind tube, and the ring is off center. To conform to the inner surface of the pouch. Provide the end of the loop or knot on the outer end of the ring® 6 for fixation to fasten the crystal to the pocket or blind tube via fibrosis, the fibrosis is surgically removed In addition to the central crystal cortex and the nucleus, it is carried out in the capsular bag. ί The inner end of the ring 6 may be integrally formed of the same material as the adhesive member 4, or the ring may be a separate material such as polyimine. If it is formed of a separate material, it is molded into the end portion of the adhesive member 4 or if the crystal lens is cut by a lathe, the loop is joined after the manufacture of the crystal body. Therefore, it has been shown and described that it is ideally included Optics and crystals of Shixi resin 'The resin-bonded plate has a loop at its distal end, and the ring can be different from the material of the plate and provide fixation and centering of the crystal in the eye. The close-packed Niang + +, The movement of the pipe formed by the dazzling of the sac and the posterior sac before the person's bag is displayed at the center and the back. The spheroidal system of the elastic elastic member is formed by stretching the longitudinal axis of the crystal of the crystal as a rubber band. Allowing the optical material to move with the buckling of the borrowing piece and the stretching of the wide elastic. Various modifications, improvements, modifications and other uses of the present invention after studying the present specification together with the drawings and the scope of the patent application. And the application will be for the invention of the technology, and it will be easy to see. This application does not deviate from this: all changes, improvements, modifications and other uses of the knowledge and scope are to be Covered by the scope of patent application. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a front view of a preferred embodiment of a preferred flat soil of the present invention. 12 200843707 FIG. 2 is a side view. 3 is a detailed view of the hinge with the widened hinge base. Back to Fig. 12 shows a variation of the fastener. According to the present invention, the m ^ & citric acid, Kola 丄 f department is a foldable, flexible (four) tree wax, C-fold plastic material, and the dense plate member will be able to withstand more and more Foldable materials, such as Shi Xi resin, water = silent material. Preferably, the end of the 'dense panel has substantially the same; the garment is placed and hinged to the optic. Kai Xi Gu [Main component symbol description] 1 : Artificial crystal 2 : Optical part 4 : Flexible extension / Adhesive 6 · Claw fishing / ring 8 : End I 〇: Hinged piece II : Hinged width 12 · Base Seat 13: Sharp 360 degree edge 14: Thickness 1 6 : Ridge 13