200824646 九、發明說明： 【發明所屬之技術領域】 本創作為橫跨數健觸_顧下難生的發明，運用处仍 無線射頻技術作為植人式生醫元件及裝置所需的能量來源及資料傳輸 的方式’使植人式生醫裝置擁有長期穩村細能量來源，而不需置 放電池’並增加了生醫裝置之$活度。朗者藉由調整與設定不同的 控制參數與電路設計，接收狀裝置之回舰號可提供進行連續與 即時的各種生理數據檢測功能、並作為植入式藥物釋放系統· 【先前技術】 、卿技術最早運餘轉敵我辨齡統，之後發展藉由植入之方 運用於追蹤牛隻上。隨後便杨各種物件資料追縱、識別等自 動辨識系統敏，如：員工卡、魚標籤（追蹤奴迴游雜）、動物植 入晶片、捷運悠遊卡、門禁管制、商店防盜、貨物生產管理、運輸等。 RFID系統主要由讀取器（Reader)、標藏（Tag)、主機（脑）三 部分所組成。讀轉德成元件包括控制歡、義餘、收發天線。 控制模組透财財式的RS232介域是無職芽之对接收主機所 下達的指令，操控射頻模組發射所需之信號，以讀取或寫人標藏内之 $料。標籤峨元件包括微晶片、控制電路、麵模組 '收發天線。 S標籤感應職取ϋ所發射之無線電㈣，標籤之控制電路會將此_ 無線電波能量轉触m朗建之賴歡、天雜崎載資訊。 主機則以鱗或有線之方式連接讀取器，其内部應酿式加以控制讀 取器之信號收發，以對標籤進行識別與管理等相關工作。 植入式生醫裝置在現代醫學中已獲得廣泛之應用，如將微型生醫 裝置植入人體内，已進行各生理資訊之監測，或對器官、組織進行控 6 200824646 w以及作祕物槪裝置。隨人式生醫裝置不需通過皮膚或腸胃 肖化系、先故各種干擾因素大為減少，提供了與人體間良好之匹配性， 有使用方便舒適等優點。尤其針對器官、組織，可作即時性之調 、 控，對於修復身體機能與監控病情有相當大之助益。 +、目紐人式生醫裝置之能絲源可分為:⑴於植人式裝置内置放 私池（2)利用外部導線傳輸能量。如此植入式生醫裝置當内置電池耗 鱗，便需再次開刀取蚊換之，造成病患暖與降低裝置之可靠度。 右衣置使用外口|5电源，利用導線之有線傳輸，則可能造成傷口之感染。 • 如新狀心_律器，制年限為三年、五年衫獨十年，便 而更換電池以確保轉$之正常運作；相較於其它植人式生醫裝置而 1，心臟轉11屬於省電之顧，因此具備長達十年之㈣壽命。倘 右植入式生醫裝置除本身運作功能外，並財各式感·以及資料傳 輸回饋等功月匕，其所需之運作電力便非電池所能滿足。 【發明内容】 、本明4點為創作4-個賴RFID絲射髓術作為其能量來 φ I、^料傳輸方式之植人式生醫裝置。賴RFID無線射頻技術於植入 气生酉衣置中便可由體外向體内提供直流電源，供給植人式裝置電 路運作，而無需於植入式生醫裝置中置放電池、或體外電源之導線傳 〗而使用者更可透過項取器下達各種命令，控讎人式生醫裝置動 作，以發揮功能、達成目的。 運用RFID絲軸技練供植人式生醫裝置能量及資料傳輸之 方式，分為二部份： (1)植入式生醫裝置 依使用上&求封二雜人式生醫裝置電路，植人式檢測生醫裝 7 200824646 置、植入式藥物釋放生醫裝置。此二種植入式生醫裝置載有控制電路 與感應線圈，能夠在接受到體外控制裝置所發射之電磁波後，轉換為 裝置運作所需之電源。 . (2)體外控制系統 此系統將電源藉由發送器以射頻(Radio Frequency，RF)方式傳送至 已植入體内之生醫裝置中，植入式生醫裝置之小型感應線圈則從中感 應出射頻電壓’該射頻電壓經整流、濾波、穩壓後產生穩定之直流電 壓，直接供給植入式生醫裝置運作。 # 【實施方式】 由於此發明同時涉及多個相異領域之應用，因此在實施上我們預 定要點來循序漸進的完成，在此將實施重點作一描述： 1、 植入式生醫裝置依使用上需求之不同，設計二種植入式生醫裝置 電路來滿足各種處理程序。 2、 設計一，植入式檢測生醫裝置。設計上將各種生理感測器置入植 入式生醫裝置中，使裝置具有隨時監控人體中各項生理參數 (如，體溫、灰壓、血糖值）之功能，並可隨時回傳各項參數之 _ 變化狀況與相關訊息。 3、 設計一中，各感測器與RFID天線皆由一控制電路所控制，負責 各感測器之動作，並將所量測得知之各項訊息藉由天線回傳至體 外控制系統。 4、 設計二，植入式藥物釋放生醫裝置。設計上此植入式生醫裝置具 有一藥物釋放系統，可在接受體外控制系統所下達之命令後動 作，針對各種病症與植入部位之不同，定時、定量釋放藥物至人 體中，達成治療之效果。 8 200824646 5、設計二之藥物釋«統與RFID天線由-控氧路所控制，此控 制私路在接收體外控制系統所下達至命令後，便作動藥物釋放系 統，完成命令之要求，並可回報系統運作狀況至體外控制系統， 供專業醫療人員作各項參數之修改。200824646 IX. Invention Description: [Technical field of invention] This creation is an invention that spans the number of health touches, and uses the radio frequency technology as the energy source for implanting biomedical components and devices. The way the data is transmitted 'allows the implantable biomedical device to have a long-term steady source of fine energy without the need to place the battery' and increases the $activity of the biomedical device. By adjusting and setting different control parameters and circuit design, the receiver can provide continuous and immediate physiological data detection functions and as an implantable drug release system. [Previous technology] The earliest technology transfer to the enemy is my age, and then the development is used to track the cattle by the implant. Subsequently, Yang will automatically identify and identify various object information such as employee cards, fish labels (tracking slaves), animal implanted wafers, MRT travel cards, access control, store security, and cargo production management. Transportation, etc. The RFID system is mainly composed of a reader (Reader), a tag (Tag), and a host (brain). Reading and translating components include controlling the Huan, Yi Yu, and transmitting and receiving antennas. The RS232 interface of the control module is a command issued by the receiving host to the receiver, and the signals required for the transmission of the RF module are manipulated to read or write the contents of the tag. The tag component includes a microchip, a control circuit, and a surface module 'transceiver antenna. The S-tag is used to take the radio (4), and the control circuit of the tag will turn this _ radio wave energy into the building of Lai Huan and Tian Zaoqi. The host is connected to the reader in a scale or wired manner, and the internal control should be used to control the signal transmission and reception of the reader to identify and manage the label. Implantable biomedical devices have been widely used in modern medicine, such as implanting micro-medicine devices into the human body, monitoring various physiological information, or controlling organs and tissues. Device. The human-type biomedical device does not need to pass through the skin or the gastrointestinal tract. The various interference factors are greatly reduced, providing a good match with the human body, and having the advantages of convenient use and comfort. Especially for organs and tissues, it can be used for immediate adjustment and control, which is quite helpful for repairing body functions and monitoring the condition. +, the source of the new-type biomedical device can be divided into: (1) built-in illuminating pool in the implanted device (2) using external wires to transfer energy. Such an implanted biomedical device needs to be re-opened for mosquito replacement when the built-in battery consumes scale, thereby causing the patient to warm and reduce the reliability of the device. The right clothes are placed on the external port|5 power supply, and the wire is transmitted by wires, which may cause wound infection. • If the new heart_law is limited to three years and five years, the battery will be replaced to ensure the normal operation of the transfer. Compared with other implantable biomedical devices, the heart turns 11 It belongs to the power-saving care, so it has a life span of ten years. If the right implantable biomedical device has its own function, and it has a variety of senses, as well as data transmission and feedback, the required operating power is not met by the battery. [Summary of the Invention] This is a 4th point of the creation of a 4-fold ray RFID ejaculation as a plant-type biomedical device with its energy transmission method. Lai RFID wireless radio frequency technology can be used to provide DC power to the body from the outside of the body, and it can be supplied to the implanted device circuit without placing the battery or the external power supply in the implanted biomedical device. The wire is transmitted and the user can issue various commands through the item picker to control the action of the human biomedical device to perform functions and achieve the purpose. The use of RFID wire shaft to train the energy and data transmission of implantable biomedical devices is divided into two parts: (1) implanted biomedical device according to the use of & seal two miscellaneous biomedical device circuit , implanted test biomedical equipment 7 200824646 placed, implanted drug release biomedical device. The two implanted biomedical devices carry a control circuit and an induction coil, which can be converted into a power source required for operation of the device after receiving electromagnetic waves emitted by the external control device. (2) In vitro control system This system transmits the power source to the biomedical device implanted in the body by radio frequency (RF) method through the transmitter, and the small induction coil of the implanted biomedical device senses The RF voltage is rectified, filtered, and stabilized to produce a stable DC voltage, which is directly supplied to the implanted biomedical device. # [Embodiment] Since the invention involves multiple applications in different fields at the same time, we have scheduled the completion of the implementation in a step-by-step manner. Here, the implementation focus will be described as follows: 1. The implantable biomedical device is used. Different requirements, the two implanted biomedical device circuits are designed to meet various processing procedures. 2. Design one, implantable detection biomedical device. The utility model is designed to put various physiological sensors into the implanted biomedical device, so that the device has the function of monitoring various physiological parameters (such as body temperature, gray pressure and blood sugar value) in the human body at any time, and can return various items at any time. Parameter _ change status and related information. 3. In design one, each sensor and RFID antenna is controlled by a control circuit, which is responsible for the action of each sensor, and the measured information is transmitted back to the external control system through the antenna. 4. Design 2, implanted drug release biomedical device. The implantable biomedical device is designed to have a drug release system that can be acted upon by a command issued by the external control system to periodically and quantitatively release the drug into the human body for treatment of various diseases and implant sites. effect. 8 200824646 5. The drug release of the design II system and the RFID antenna are controlled by the controlled oxygen circuit. After the control of the private circuit is received by the external control system, the drug release system is activated to complete the command. Report the system's operational status to the external control system for professional medical personnel to modify the parameters.
6此一種植入式生醫裝置設計上無需電池，而改以RPJD系統中標 鐵之控制電路，並配合一倒F型天線(PIFA，P1_ Inverted F6 This kind of implantable biomedical device is designed without battery, but changed to the control circuit of the standard iron in RPJD system, and with an inverted F antenna (PIFA, P1_ Inverted F
Antemia)以接收體外控制系統所發射之電磁波，並轉換為裝置運 作所需之電源。 7、體外控制系、统由一電腦主機與即仍讀取器所組成。此系統能夠 在人為操作或是程式控制之下，在特定時間或固定時間間隔發射 RF電磁波’以提供此控制系統所管轄之植入式生醫裝置能量來 源。 8 ^，州無線通訊委員會（European RadiocommunicationsAntemia) receives the electromagnetic waves emitted by the external control system and converts them into the power required for the operation of the device. 7. The external control system consists of a computer host and a still reader. The system is capable of transmitting RF electromagnetic waves at specific times or at fixed time intervals under human or program control to provide an implantable biomedical device source of energy governed by the control system. 8 ^, State Wireless Communications Committee (European Radiocommunications)
Committee’ERC)在1996年將402〜405MHz頻段分配給植入式醫 療裝置通信服務(Medical Implant Communications Services band， MICS)，因此選定該頻段中4〇2MHz作為體外控制系統發射之頻 率0 9、體外控制系統所發射之電磁波功率最高為86mW，以符合美國聯 邦通信委員會FCC之規範。 【圖式簡單說明】 圖1為本發明設計一之植入式檢測生醫裝置架構示意圖 圖2為本發明設計一之電路示意圖 圖3為本發明設計二之植入式藥物釋放生醫裝置架構示意圖 圖4為本發明設計二之電路示意圖 9 200824646 圖5為倒F型天線（PIFA) 圖6為PIFA天線植入於人體中之位置示意圖 圖7為體外控制系統電路示意圖 【主要元件符號說明】 A. 體外控制系統 B. 讀取器收發天線 C. 植入式檢測生醫裝置 D. 植入式生醫裝置之控制晶片 E. 生理感測器 F. 倒F型天線（PIFA) G. 植入式藥物釋放生醫裝置 H. 藥物釋放系統 I. RFID讀取器 J.主機糸統Committee'ERC allocated the 402~405MHz band to the Medical Implant Communications Services (MICS) in 1996, so the frequency of 4〇2MHz in this band was selected as the frequency of the external control system. The electromagnetic wave power emitted by the control system is up to 86mW to comply with the Federal Communications Commission FCC regulations. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic diagram of a structure of an implantable detection biomedical device according to a design of the present invention; FIG. 2 is a schematic diagram of a circuit design of the present invention; FIG. 3 is a schematic diagram of an implantable drug release biomedical device structure of the second design of the present invention. 4 is a circuit diagram of design 2 of the present invention. 200824646 FIG. 5 is an inverted F antenna (PIFA). FIG. 6 is a schematic diagram of a position where a PIFA antenna is implanted in a human body. FIG. 7 is a schematic diagram of a circuit of an external control system. A. In vitro control system B. Reader transceiver antenna C. Implantable detection biomedical device D. Implanted biomedical device control wafer E. Physiological sensor F. Inverted F antenna (PIFA) G. In-line drug release biomedical device H. Drug release system I. RFID reader J. Host system