200822942 九、發明說明： 【發明所屬之技術領域】 本發明係關於-種可撓性之具電刺激及電促渗之端帶，此端帶含有電 極，此電極可密合的、且容易的貼附在身體的任何部位，可作為電刺激電 極或可作為電促滲作用。 【技術背景】 編帶常相於保護受到燒傷及其他外鮮傷害的皮膚，雖然也會偶爾 使用會促進彳〶12癒合的細帶等，但基本上這些繃帶都^是做外部固定戍保 護之用，«顧織物作為包紮之用，很少有其他功能。另外每個人或多 或少都會有手腕或關節疼痛的經驗，或運麟為了保護手腕或膝蓋關節， 會帶上護膝、或護腕等。在物理治療上，也會光、電、冷熱、力等物 理因子來促進病患的復健或治療絲等。例如，我們都知道，微波是一種 電磁波，利用微波造成水分子的缝，可以加熱食物。在物理治療中，就 利用此特性’控制-定輸出量，可振盈人體組織内水分子，提高深部組 織/m度，加速金液循環，促進患部癒合速度，減輕疼痛。另外也常用電刺 激治療-包括干擾波、低^週波電刺激，經皮神經電刺激器等。 1/ <最早使用電刺激來治療骨關節疾病可追溯到西元前四世紀。當時的希 月“人和羅馬人發現-種魚可產生—百至—百五十伏特的電流。他們就利用 适種魚產生的電流來治療足部關節炎。電刺激治療風濕關節炎最重要的目 的疋止痛，此外，電刺激也可以用來增強肌力，延緩或避免肌肉萎縮，減 輕肌肉痙攣和增進血液循環。 曰電刺激的種類很多，其中與骨關節疾病之治療有關的可分為兩大類·· 一是低頻波（一般稱為經皮神經電刺激），另一則是中頻波（一般稱為中頻 干擾波）。低頻波是指頻率在1000以下的電波，一般多採用〇〜100;中 頻波的頻率是1000〜1000000 (一百萬）之間，但頻率超過1〇〇〇〇 ’（壹 萬）以上的電波會產生熱，所以臨床上中頻波頻率均在1000至100⑼之 間。經皮神經電刺激就是把電流通過黏在皮膚上的電極，以達刺激神經而 5 200822942 得止痛的效果，成效不錯且無副作用，病人甚至可以買回家自行使用。 中頻干擾波4又疋採用兩組電極（一組兩個），其頻率相差為〇〜1⑼之 間，如4100及4000，通電後兩組電極會以中頻波穿透皮膚，而在深部 組織發生電流干擾，產生-個〇〜議的低頻波。採射頻波的原因是穿 ^ 透皮膚較容易，對皮膚的刺激也小，電流強度可以調得較大。 臨床研究顯示，電刺激對於下背痛、退化性關節炎、類風濕性關節炎、 •韋刃帶扭傷、肌腱炎（如網球肘）、肌肉及肌膜疼痛症候群等均有顯著的成效。 電刺激直接有止痛及肌肉放鬆效果。很多慢性關節炎病人因為長期藥物治 療而導致胃及十二指腸潰瘍，也可以考慮合併使用電刺激，以減少藥物的 ,使用。此外，雷諾氏症候群病人或是交感神經失營養症者，也可用電流刺 ,部患處或相關的交感神經節，以增進血液循環。而當風濕關節炎病人 發，週邊神經病變時，也可用電做來減輕疼痛或是延緩肌肉萎縮。本發 Γ疋一種方便使用具可撓性平面雜之繃帶，可作為激之用，亦可作 為電促滲之用，故本發明具有產業上之利用性。 【先前技術】 傳統上_帶都是織物作成長條型，作為外部@定或靜之用， ’很少有其他魏。轉統上的電舰電極也都只是點式電mi有全屬 ==用以連接電源’ @此制衫舒服。電極底域底面邊緣雖有屬 但易聽，尤其是重複使用後、或走動或運動時候。因此有固 ’而蹲帶或'娜強固定時，因有金屬凸出物使用 上亚不舒適。且電刺激的範圍小，只是—個或幾個固定點而已。 =料-般也可猶離子t滲法，駿縣是彻電如促進藥物 膜進到體内。電促渗法使用脈衝式電流或持續不間斷電流將 =猎=離子促_透進人皮膚或黏膜㈣給藥技術，包括· 利用電促渗法時，生物活性物質經皮電渗入 里通過的⑨何直接成_，這也要依據所提供的電流、電流提供的持 6 200822942 促滲作用電極分隔接觸的皮膚表皮區等性質。雷^ 法的優點包括可以促進藥物進人體内、加速藥物的 促淨 樂物進入體_量及時間；換句話說，—旦電源=、且=易控制 者’不管持續的或跳動的給藥方式需要與否，利 ===， 達到理想的輸入動力。文獻上關於電促滲，已圖表可 物（Mmer LL，Smith G A. Int J Phann，NQ49> pi5 二二=離子性藥 (Siddiqui 〇5 Roberts M S Pl〇ack AE Ph du ) %離子性藥物200822942 IX. Description of the Invention: [Technical Field] The present invention relates to a flexible end band with electrical stimulation and electro-osmosis, the end band containing an electrode, which can be closely and easily Attached to any part of the body, it can be used as an electrical stimulation electrode or as an electro-osmotic effect. [Technical Background] Tapes are often used to protect skin from burns and other external injuries. Although they are occasionally used to promote the healing of tendon 12, basically these bandages are protected by external fixation. Use, «Gu fabric as a dressing, rarely have other functions. In addition, each person will have more or less experience of wrist or joint pain, or Yunlin will wear knee pads or wristbands to protect the wrist or knee joint. In physical therapy, physical factors such as light, electricity, heat, and force are also used to promote the rehabilitation or treatment of patients. For example, we all know that microwaves are electromagnetic waves that use microwaves to create water molecules that can heat food. In physiotherapy, this characteristic is used to control-fix the output, which can oscillate the water molecules in the human tissue, improve the deep tissue/m degree, accelerate the circulation of gold liquid, promote the healing speed of the affected part, and alleviate the pain. In addition, electric stimulation therapy is also commonly used - including interference waves, low-cycle electrical stimulation, and transcutaneous electrical nerve stimulators. 1/ <The earliest use of electrical stimulation to treat bone and joint diseases dates back to the fourth century BC. At that time, Xiyue "people and Romans discovered that the fish can produce - hundreds to 150 volts of current. They use the current generated by the fish to treat foot arthritis. The most important purpose of electrical stimulation for rheumatoid arthritis. In addition, electrical stimulation can also be used to enhance muscle strength, delay or avoid muscle atrophy, reduce muscle spasm and improve blood circulation. There are many types of electrical stimulation, among which the treatment of bone and joint diseases can be divided into two categories. · · One is the low frequency wave (generally called transcutaneous electrical nerve stimulation), the other is the intermediate frequency wave (generally called the intermediate frequency interference wave). The low frequency wave refers to the frequency below 1000, usually more than 100~100 The frequency of the intermediate frequency wave is between 1000 and 1000000 (one million), but the frequency above 1〇〇〇〇' (壹万) or more will generate heat, so the clinical intermediate frequency is between 1000 and 100 (9). Between the transcutaneous electrical nerve stimulation is to pass the current through the electrode stuck to the skin, in order to stimulate the nerve and 5 200822942 to achieve analgesic effect, good results and no side effects, the patient can even buy home The IF interference wave 4 uses two sets of electrodes (one set of two), and the frequency difference is between 〇~1(9), such as 4100 and 4000. After energization, the two sets of electrodes will penetrate the skin with medium frequency waves. In the deep tissue, current interference occurs, and a low-frequency wave is generated. The reason for the radio frequency wave is that it is easy to wear through the skin, the skin stimulation is small, and the current intensity can be adjusted larger. Clinical studies have shown that Electrical stimulation has significant effects on lower back pain, degenerative arthritis, rheumatoid arthritis, • Wei sprained sprain, tendonitis (such as tennis elbow), muscle and sarcolemma pain syndrome. Electrical stimulation directly has pain relief. And muscle relaxation effects. Many patients with chronic arthritis cause gastric and duodenal ulcers due to long-term medical treatment. It is also conceivable to use electrical stimulation to reduce the use of drugs. In addition, patients with Raynaud's syndrome or sympathetic dystrophy Current spurs, affected parts or related sympathetic ganglia can also be used to improve blood circulation. When patients with rheumatoid arthritis develop peripheral neuropathy, they can also use electricity. To reduce pain or delay muscle atrophy. The present invention is convenient for use with a flexible flat bandage, which can be used as an excitability or as an electro-osmotic, so the invention has industrial applicability. [Prior Art] Traditionally, the belts are made of fabrics for growing strips, as external @定或静的用, 'There are few other Wei. The electric ship electrodes on the transfer system are also all point-type electric meters have full ownership= = Used to connect the power supply @ @ This sweater is comfortable. Although the bottom edge of the electrode bottom field is versatile, it is easy to listen, especially after repeated use, or when walking or moving. Therefore, there is solid 'and the belt or 'Naqiang fixed, because There are metal protrusions that are uncomfortable to use in the upper Asia. The range of electrical stimulation is small, only one or a few fixed points. = material-like can also be used to infiltrate the method, Junxian is the electricity to promote the drug film into Into the body. Electroporation uses pulsed current or continuous uninterrupted current to pass the test to the human skin or mucous membrane (4). Including the use of electroporation, the bioactive substance is transdermally The 9 passed through the infiltration into the _, which is also based on the Holding properties epidermal penetration 6200822942 zones separated working electrode in contact with the current, the current supplied. The advantages of the Ray method include promoting the entry of the drug into the body, accelerating the entry of the drug into the body, and the time; in other words, the power supply = and = the controller is controlled regardless of the sustained or beating administration. Whether the mode needs or not, profit ===, to achieve the ideal input power. In the literature, it is characterized by electrophoresis. (Mmer LL, Smith G A. Int J Phann, NQ49> pi5 22 = ionic drug (Siddiqui 〇5 Roberts M S Pl〇ack AE Ph du ) % ionic drug
No.37, P732, (麻醉劑）、腎上腺素、甲美资 ^木上也有使用利多卡因 Ο ^ ^ ^ 、 土 ’ 戈匕权(methyl predonis〇l〇ne )及消炎止痛蘂 ^療讀疱輸條痛（小澤明，日本醫事新報，ν。.侧，防，=)梁 特徵ί=ί=4ΓΓ，19Γ成年=一 Γ經皮施藥器及其電極4 ^—之至少_電極元件内’内含該藥物； 力來源。我國專利第00199865(1993年)號揭露一種「皮膚用電極n 皮藥物輸送裝置」，其特徵在於穿皮藥物輸“包括 二帝彳孔絶緣層位於電極一側並滲有所要輸送之藥液，一液體貯器位 二極另-側，及—可位移則可控做體自職經 至 絕緣層。我國專利第00刪5(1999年)號揭露一種「離子 ，:提供—種離子滲透法所用電極裝置，具有來自電極的金屬離子不2 可再_ ’低廉而量產性優良，抑制引起分極的氣體發生不^ 透過電流，並防止長期使用時因pH變化損傷皮膚等優良 專利弟〇_〇24〇(2_年)號揭露一種「離子電滲療法用裝置」 2 將藥物作電氣式經皮膚投與讀子電滲躲略置，其職t支持體上 t備電源，、同時在該支持體之同_單社配置施體與受體，令兩者間介著 絕緣用空隙部，而形成-體構造，雜子電滲療法用裝置不必增加電流值 即可安全又有效地使藥物經皮膚吸收，且處理性甚優良。我國專利第 〇〇姻3〇9(2〇〇〇年)號揭露一種「電極及離子電滲設備及方法」，係揭露一種 電極及離子電滲設備及方法，其中，電極展現變化的電阻。在電極形狀方 200822942 已揭路者冑在同丨面上m纟g緣體排列配置複數個施體與受體者 (日本觸平3_脳64號），或為__式控财財效成分之釋出的目 的’而將複數個施體與受體配置成同心圓狀者（日本特開平楊祕號）. :’驗_除麟部之糕_，而相—平面上形成有與皮膚接觸 。刀之、％緣和並將多角形施體介著絕緣部包含在受體中者（日本特開平 進—步’日本特開平Μ3464號中，係使用多數個受體以 吸收之目的，但即使增加受體數量，吸·錢料會提高。而且 特開平4-2〇8166號中，雖然在未有任何根據下即陳述同心圓狀電極裝置可 η υ ::=Γ需電流抑制於最小限度’但事實上，縱使是同心圓狀電極， 二及收性亦會因絕緣部之距離及紐與受體之面義料素而改變。又， 特，平8·185〇16號中，絕緣部係以具有與皮膚接觸的部分 =種構造與其說是科抑雛聽紐與受體間之電流 ^、牛 有嫌，故以此為辅助謝法。以電極塾而言 == 號;示-種含有水分，對歧《良好祕著力 不s產生形悲等之變化者。不過，即使有此等 人滿意之離子電渗療法用之農置。 貝際上仍未械供令 縱觀社資料顯示，傳統上的電促渗雜，軸侧面 有_電舰電極的金屬凸恤，用以連接電源，且電極下端_ = =物儲存槽的突起裝置，因此使用上更不方便。電極底面或底^ -層黏貼劑，其缺點也與—般電刺激電極雷同，不㈣定、易、’ ，、是重複使用後。且一般無法在走動、或運動時候使用。 /备 本發明為克服以上的困難及缺點，改良電極與電線的連 ==使用ίΓ捷性平面電極之端帶，電極的刺激作用面1或= 尸、、積又*，，、金屬電極凸出知，使用上舒適方便，容易固定、π县脱 1性至在走動’動時候也可使用。因本創作為可 &千面_ ’可以做成齡方式，方便姻且蚊牢靠。傳統上使用電 8 200822942 面電極之 刺激時，都不能走動或行走，本發明棚齡式固定之可捷性 電極，則不受賊落之_，縱使進行賴激時亦可走^ 療 性 他的事情，可有效的利用時間做其他的事情，同時可進行電刺激及 恭。’且元全避免點式電極版帶來糾方便，故本翻具有新酿與進^ 【發明内容】 〇 本發明是-種雜使肚具可雜平面電極之娜，以電極 可i=trr版綱獅_#_，帐為大面積之 祕+面電極，如圖一所示。可撓性平面電極之端帶山、 雷其上有可撓_極(電極3、電極4)，此電極是由—可挽性二Ί V-电電極面、絕緣區⑺、電極接端、控制器⑹及-曰 端帶上之電,等。而 直他導雷末或祕包括金、銀、銅、鐵或 端帶上電極:二:21此可撓輸可用導電布或導電纖維製成。此 面電極亦^//讀―段具有鬆緊功能之區域，使穿戴者更為舒適。平 電極(正電極2ΓΓ圓式或圓的形狀，如圖二所示’圖中示意此兩可撓性 物理治料更=電f·降及絕緣區(3G)鸲了使穿戴者在進行電刺激的 孔，(或）電極上可作為篩網狀，或具有多數個通氣 方式可以達到通氣舒適的目的與效果。可換性電極繃帶之固定 安全別二:口工、、或魔術沾式、或使用黏著劑、或使用膠帶式、或使用 文王別針、或打平結等方式加以固定。 式可利及電促/夢有各種不同的模式，此電極電刺激及電促渗之模 控制哭介=器控制性。控制器可控制電刺激或電促渗的電流波型式，此 °亦可進-步可控制電刺激成類似敲、打、擊'或捏等模式。 波形仃電促滲作用時，控制器亦可進—步可控制產生適當頻率、 作用，、^小的電流或電壓。本裝置可藉由電觀與電促滲的雙重促滲 生物活性物質可以有效、快速地經由皮膚或黏膜進人體内組織， 200822942 以達到所需之效果。電促渗作㈣，電流或電射為連續式或間歇式。 此種可撓性平面電極之繃帶，其電刺激作用之面積大，又無金屬電極 及凸出釦，使用時可以繃帶形式纏繞。因此方便使用且固定牢靠。傳統上 使用電刺激時，都不能行走或行動自如，本發明__是固定之可挽性 平面電極之電刺激，則不受易脫^之限制，縱使進行電刺激時亦可走動、 看電視或做其㈣事情，可有效的進行電織麟理治療，且完全避免點 式電極片所帶來的不方便。具可撓性電極之繃帶，此端帶上之電極具有可 生可a &貼附於身體的任何部位，例如關節、手腕、或膝蓋處。 η 、貫施方式一】 根據本發明，具可撓性平面電極之端帶的固定步驟如_ 1·將繃帶的一端斜放在肢體或關節上。 2·沿著肢體環繞-圈，讓可撓性平面電極可以密 4·最後利用相關之固定裝置將繃帶固定。 1 下 【實施方式二】 根據本發明，具可撓性平面電極之 — (2〇)或電極(30)上，端視藥物性質而定。若藥物 ^射勿槽可在電極 極上。若藥物帶負電荷，則藥物 朽T、’則藥物槽在正電 •所示 絕緣_-概度，卿 上°=__隔開， 【實施方式三] 根據本發明，具可撓性平面電極之端帶進行 電路可為如圖四所示，電流波形可為如 。:彳、、控制器之邏輯 的施予方法，但本發明並不只侷限於以上=以上僅是舉例幾種常用 撓性具電刺激及電促滲之端帶、與施用方法Τ發明相關聯的可 白本务明的涵蓋範園内。No.37, P732, (narcotics), adrenaline, and A. sinensis also use lidocaine Ο ^ ^ ^, soil 'go predonis〇l〇ne' and anti-inflammatory painkiller Loss of pain (Ozawa, Japanese medical report, ν.. side, defense, =) beam characteristics ί=ί=4ΓΓ, 19Γ adult = one transdermal applicator and its electrode 4 ^ - at least _ electrode element 'Including the drug; source of force. Chinese Patent No. 00199865 (1993) discloses a "skin electrode n-skin drug delivery device", which is characterized in that the transdermal drug delivery "includes the second emperor pupil insulating layer on the side of the electrode and permeates the drug solution to be delivered. A liquid reservoir is located on the other side of the pole, and - the displacement can be controlled to be self-employed to the insulating layer. Chinese Patent No. 00, deleted 5 (1999) discloses an "ion, provide - ion permeation method" The electrode device used has a metal ion from the electrode which is not cheaper and has excellent mass productivity, suppresses the generation of a gas which does not pass through the gas, and prevents the patent from being damaged by pH changes during long-term use. 〇24〇(2_年) No. discloses a device for iontophoresis. 2 The drug is electrically cast through the skin and the reader is electro-osmotic to hide, and the t-support is used to support the power supply. The support body and the acceptor are arranged such that the gap between the two is formed between the donor and the acceptor, and the device for the hetero-electroosmotic therapy can be safely and effectively made without increasing the current value. The drug is absorbed through the skin, and the treatment is very excellent. China Patent No. 3〇9(2〇〇〇年) discloses an "electrode and iontophoresis apparatus and method" which discloses an electrode and iontophoresis apparatus and method in which an electrode exhibits a varying electrical resistance. In the shape of the electrode side 200822942, the person who has revealed the 纟 缘 纟 纟 缘 缘 缘 缘 缘 ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( ( The purpose of the release of the ingredients 'and the plurality of donors and receptors are arranged in a concentric shape (Japan Special Kaiping Yang Mi). : 'Inspection _ In addition to the Lin cake _, and the phase - formed on the plane skin contact. The knives, the % edge, and the polygonal donor body are included in the receptor through the insulating portion (Japanese Patent No. 3464, Japan uses a number of receptors for absorption purposes, but even Increasing the number of receptors, the amount of suction and money will increase. And in No. 4-2〇8166, although there is no basis to state that concentric circular electrode devices can be η υ ::= 电流 current is suppressed to a minimum 'But in fact, even if it is a concentric electrode, the second and the receiver will also change due to the distance between the insulation and the surface of the element and the receptor. In addition, special, Ping 8·185〇16, insulation The part of the department has contact with the skin = the structure of the species is not related to the current between the receptor and the receptor, and the cow is suspected. Therefore, it is used as an auxiliary method. - The kind of water contains water, and the difference is that the good secrets do not produce the sorrow and other changes. However, even if there is such a satisfactory ion-osmotic therapy for the farm, there is still no equipment available. The data shows that the traditional electro-osmotic seepage, metal embossed with _ electric ship electrodes on the side of the shaft, used to connect Connected to the power supply, and the lower end of the electrode _ = = the protruding device of the object storage slot, so it is more inconvenient to use. The bottom surface of the electrode or the bottom layer-layer adhesive is also the same as the general electric stimulation electrode, not (four) fixed, easy, ',, is after repeated use, and generally can not be used during walking or exercise. / The present invention is to overcome the above difficulties and shortcomings, improve the connection of electrodes and wires == use the end belt of the planar electrode, electrode The stimulating effect surface 1 or = corpse, and product *,,, metal electrode protruding, known to be comfortable and convenient to use, easy to fix, π county off 1 to the use of walking can also be used. Because this creation is &千面_ ' can be made into a younger way, convenient for marriage and mosquitoes are reliable. Traditionally, when using the electric 8 200822942 surface electrode stimulation, they can not walk or walk, the sturdy fixed electrode of the present invention is not Being thieves _, even if you are going to take care of him, you can use time to do other things, and at the same time you can perform electrical stimulation and Christine. 'And the full avoidance of the point electrode version brings Convenient, so this has Brewing and entering ^ [Summary of the invention] 〇 The present invention is a kind of miscellaneous so that the belly can be a hetero-planar electrode, the electrode can be i=trr version of the lion _#_, the account is a large area of the secret + surface electrode, as shown As shown in the figure, the end of the flexible planar electrode has a mountain, and the ridge has a flexible _ pole (electrode 3, electrode 4), the electrode is made of - a removable Ί V-electrode surface, an insulating region (7), Electrode terminal, controller (6) and - end of the belt with electricity, etc. and straight to lead the end of the mine or secret including gold, silver, copper, iron or end with the upper electrode: two: 21 this can be used to flex the conductive cloth Or conductive fiber. This surface electrode also has a region with elastic function to make the wearer more comfortable. Flat electrode (positive electrode 2 round or round shape, as shown in Figure 2) It is indicated that the two flexible physical materials are more electric=flowing and insulating area (3G), so that the wearer can perform electric stimulation on the hole, or the electrode can be used as a mesh, or have a plurality of ventilation modes. The purpose and effect of ventilation comfort can be achieved. Removable electrode bandages are secure. 2: Oral, or magic-stick, or use adhesive, or use tape, or use a king pin, or tie the knot to fix. There are various modes that can be used for electricity and electricity. The electrode is electrically stimulated and electroporated to control the crying control. The controller can control the current wave pattern of electrical stimulation or electro-osmotic, and the step can also control the electrical stimulation into a pattern like knocking, hitting, hitting or pinching. When the waveform is osmotic, the controller can also control the current or voltage to generate the appropriate frequency, action, and voltage. The device can be double-penetrated by electro-optical and electro-osmotic. The bioactive substance can effectively and quickly enter the body tissue through the skin or mucous membrane, 200822942 to achieve the desired effect. Electro-osmotic (4), current or electric radiation is continuous or intermittent. The bandage of the flexible planar electrode has a large area of electrical stimulation, and has no metal electrode and protruding buckle, and can be wrapped in a bandage when in use. Therefore, it is convenient to use and securely fixed. Traditionally, when electrical stimulation is used, it is impossible to walk or move freely. The invention __ is the electrical stimulation of the fixed pullable planar electrode, and is not restricted by the easy-to-remove, and can also walk and watch TV even when performing electrical stimulation. Or do the (four) thing, can effectively carry out electro-textile treatment, and completely avoid the inconvenience caused by the point electrode sheet. A bandage with a flexible electrode on which the electrode can be attached to any part of the body, such as the joint, wrist, or knee. η, MODE 1] According to the invention, the step of fixing the end band of the flexible planar electrode is such that the end of the bandage is placed obliquely on the limb or joint. 2. Circumscribe the circle around the limb to allow the flexible planar electrode to be tight. 4. Finally, fix the bandage with the associated fixture. 1 [Embodiment 2] According to the present invention, the (2 〇) or the electrode (30) having a flexible planar electrode depends on the nature of the drug. If the drug does not shoot, it can be on the electrode. If the drug is negatively charged, then the drug T, 'the drug trough is positively charged · the insulation _-prepared, separated by °=__, [Embodiment 3] According to the invention, with a flexible plane The end band of the electrode can be made as shown in FIG. 4, and the current waveform can be as follows. : 彳,, the logic of the controller, but the invention is not limited to the above = the above is only a few examples of commonly used flexible electrical stimulation and electro-osmotic end bands, and the application method 相关 invention It can be covered in the Fan Park.