200808387 九、發明說明： 【發明所屬之技術領域】 本發明係關於醫療、牙醫、藥學、獸醫或喪葬儀器與 設備的微生物去活，特別是使用於液態微生物去活性系統 之過濾系統。 ” 【先前技術】 暴露於金液或其他體液之醫療、牙醫、藥學、獸醫或 ❿喪葬儀器與設備，於每次使用之間均需要徹底之清潔與微 生物去活性或消毒。液態微生物消毒系統目前已廣泛地使 用於將無法承受蒸氣消毒系統高溫的儀器或設備進行去活 性$消毒，且液態消毒系統一般而言係藉由將醫療儀器或/ 且設備暴露於如過乙酸或其他強氧化狀液態殺菌或消毒 化學物中而運作。 & /在此種系統中，待清潔之儀器或設備通常係放置在液 態微生：去活性系統内之内室中’或者在内室中的容器 内二接著於去活性循環時，將液態消毒劑循環穿過包含此 内室（及其中之容器）的液態循環系統。 =去活性循環之後，便將通常為水之清洗溶液循環穿 ^内至以除去於去活性循環時累積在儀器或設備上之微生 ^ /舌丨生殘渣或任何微粒。應可理解者為，確保清洗用水 t高度純淨以避免經微生物去活性之儀H或設備在清洗循 %中不再被污染乃相形重要。 陝火=用於清洗儀器或設備之水通常穿過過濾系統以移 之分支桿菌微粒（mycobacterium particulates )。雖 6 200808387 然於過濾系統之下游侧可保留少量之液態消毒劑，但過濾 系統之上游内容通常未經微生物地去活性或消毒，因此可 能在經過一段時間後過濾系統的上游侧將累積有微生物污 染物，且接著進入過濾系統之下游侧並於清洗循環時進入 内室。 本發明克服了上述與其他問題，並提供改良之過濾、系 統，用於過濾使用於微生物去活性系統的水。 【發明内容】 根據本發明之實施例，提供一種運作消毒器之方法， 此消毒器具有用以接納待消毒物品之内室、用以將流體循 環穿過該内室之流體循環系統、用以藉由將乾燥化學劑與 水混合以產生液態消毒劑之裝置、以及用以過濾進入該消 毒器之水的水過濾系統。此水過濾系統包含··連接至該内 室之流體供應管線，配置於流體供應管線内之方向閥，於 流體供應管線中用以過濾流過其中之流體的第一過濾元 件。此第一過濾元件係用於過濾流經其中之流體，並位於 方向閥下游、方向閥與内室之間。第二過濾元件則位於流 體供應官線中，用以過濾流過其中之流體，此第二過渡元 件係位於第i濾元件與内室之間。水管線連接至流體供 應管線上方向閥與第—過航件間之交點。分流管線連接 至流體供應管線以定義繞過方向閥與第—與第二過濾元件 之流體通道。此方法之步驟包含·· ()藉由將來自水源之水穿過第—與第二過濾、元件以 將消毒器注滿水； 7 200808387 (2) 藉由將經由第一與第二過濾元件過濾後之水與乾 燦化學劑混合以產生液態消毒劑； (3) 將液態消毒劑循環穿過流體循環系統以及過濾系 統，其中將液態消毒劑之一部分引導穿過第一與第 二過濾元件，且將另一部分引導穿過分流管線； (4) 於預設之暴露時間後排空消毒器； (5) 使清洗用水通過第一與第二過濾元件； (6) 於清洗用水通過第一與第二過濾元件後將清洗用 水加熱； (7) 將清洗用水導入内室。 根據本發明之另一實施例，提供一種運作再處理器的 方法，此再處理器具有用以接納待微生物去活性物品之内 室、用以將流體循環穿過該内室之流體循環系統、用以藉 由將乾燥化學劑與水混合以產生液態消毒劑之裝置，以及 用以過濾進入再處理器之水的水過濾系統。此該水過濾系 統包含··得連接至加壓水源之流體供應管線、第一與第二 過濾兀件，此第一與第二過濾元件係位於流體供應管線 中’且第—過濾兀件乃位第—過濾元件之下游。分流管線 連接至流體供應管線以定義繞過第—與第二過濾元件之流 體通道的，且水過遽系統係連接至流體循環系統。此方法 之步驟包含： ⑴藉由將來自水源之水穿過第―與第二過濾元件以 將再處理器注滿水； (2)藉由將經由第一與第二過嚙 币垃應7〇件過濾後之水與乾 8 200808387 燥化學劑混合以產生微生物去活性流體； (3) 將微生物去活性流體循環穿過流體循環系統以及 過濾系統，其中將微生物去活性流體之一部分引導 穿過流體供應管線，且將另一部分引導穿過第一與 第二過濾元件； (4) 於預設之暴露時間後排空再處理器； (5) 藉由將清洗用水通過第一與第二過濾元件以將再 馨 處理器注滿清洗用水；以及 (6) 於清洗用水進入内室前加熱清洗用水。 根據本發明之另一實施例，提供一種運作再處理器的 方法，此再處理器具有用以接納待微生物去活性物品之内 室、用以將流體循環穿過該内室之流體循環系統、用以藉 由將乾燥化學劑與水混合以產生液態消毒劑之裝置，以及 用以過濾進入再處理器之水的水過濾系。此水過濾系統包 含：得連接至加壓水源之流體供應管線，位於流體供應管 _線中之第一與第二過濾元件及加熱器，第二過濾元件係位 第一過濾元件之下游，而加熱器則位第二過濾元件之下 游。分流管線連接至流體供應管線以定義繞過第一與第二 過濾元件以及加熱器之流體通道，且水過濾系統係連接至 流體循環系統。此方法之步驟包含·· (1) 藉由將來自水源之水穿過第一與第二過濾元件以 將再處理器注滿水； (2) 藉由將經由第一與第二過濾元件過濾後之水與乾 燥化學劑混合以產生液態消毒劑； 9 200808387 (3)將液態消毒劑循環穿過流體循環系統以及過濾系 統，其中將液態消毒劑之一部分引導穿過流體供應 管線，且將另一部分引導穿過第一與第二過濾元件 以製造過濾後之液態殺菌劑；以及 (4)於循環步驟時運作加熱器。200808387 IX. INSTRUCTIONS: FIELD OF THE INVENTION The present invention relates to microbial deactivation of medical, dental, pharmaceutical, veterinary or funeral apparatus and equipment, particularly to filtration systems for liquid microbial deactivation systems. [Prior Art] Medical, dental, pharmacy, veterinary or funeral instruments and equipment exposed to gold or other body fluids require thorough cleaning and microbial deactivation or disinfection between uses. Liquid microbial disinfection systems are currently available. It has been widely used to deactivate and disinfect instruments or equipment that cannot withstand the high temperatures of vapor disinfection systems, and liquid disinfection systems are generally exposed to medical instruments and/or equipment such as peracetic acid or other strongly oxidized liquids. Operates in sterilizing or disinfecting chemicals. & / In such systems, the instrument or equipment to be cleaned is usually placed in a liquid micro-life: in the inner chamber of the deactivation system' or in a container in the inner chamber. The liquid disinfectant is then circulated through the liquid circulation system containing the inner chamber (and its container) during the deactivation cycle. = After the deactivation cycle, the usually water cleaning solution is circulated to remove The micro-growth/tongue residue or any particles accumulated on the instrument or equipment during the deactivation cycle. It should be understood that the cleaning water is high. Pureness to avoid microbial deactivation of the instrument H or equipment is no longer contaminated in the cleaning cycle is important. Shaanxi fire = water used to clean instruments or equipment usually through the filtration system to move mycobacterial particles (mycobacterium Particulates.6 200808387 Although a small amount of liquid disinfectant can be retained on the downstream side of the filtration system, the upstream content of the filtration system is usually not microbially deactivated or sterilized, so the upstream side of the filtration system may be after a period of time Microbial contaminants accumulate and then enter the downstream side of the filtration system and enter the internal chamber during the wash cycle. The present invention overcomes these and other problems and provides improved filtration, systems for filtration for use in microbial deactivation systems [Invention] According to an embodiment of the present invention, there is provided a method of operating a sterilizer having a fluid circulation system for receiving an inner chamber of an article to be sterilized, for circulating a fluid through the inner chamber, a device for producing a liquid disinfectant by mixing a drying chemical with water, and for filtering a water filtration system that enters the water of the sterilizer. The water filtration system includes a fluid supply line connected to the inner chamber, a directional valve disposed in the fluid supply line, and a filter in the fluid supply line for filtering a first filter element of the fluid. The first filter element is used to filter fluid flowing therethrough and is located downstream of the directional valve, between the directional valve and the inner chamber. The second filter element is located in the fluid supply line for Filtering the fluid flowing therethrough, the second transition element is located between the ith filter element and the inner chamber. The water line is connected to the intersection between the directional valve on the fluid supply line and the first-passing member. The split line is connected to the fluid supply The pipeline defines a fluid passage that bypasses the directional valve and the first and second filter elements. The steps of the method include: () by passing water from the water source through the first and second filters, components to inject the sterilizer Full water; 7 200808387 (2) Producing a liquid disinfectant by mixing water filtered through the first and second filter elements with dry chemical; (3) circulating liquid disinfectant through the fluid cycle a system and a filtration system, wherein one portion of the liquid disinfectant is directed through the first and second filter elements and the other portion is directed through the split line; (4) the sterilizer is evacuated after a predetermined exposure time; Passing the washing water through the first and second filter elements; (6) heating the washing water after the washing water passes through the first and second filter elements; (7) introducing the washing water into the inner chamber. According to another embodiment of the present invention, there is provided a method of operating a reprocessor having a fluid circulation system for receiving an inner chamber of a microorganism deactivating article, for circulating a fluid therethrough, A device for producing a liquid disinfectant by mixing a drying chemical with water, and a water filtration system for filtering water entering the reprocessor. The water filtration system comprises: a fluid supply line connected to the pressurized water source, first and second filter elements, wherein the first and second filter elements are located in the fluid supply line and the first filter element is Bit - downstream of the filter element. A split line is coupled to the fluid supply line to define a fluid passage bypassing the first and second filter elements, and the water bypass system is coupled to the fluid circulation system. The steps of the method include: (1) filling the reprocessor with water by passing water from the water source through the first and second filter elements; (2) by passing the first and second passing coins 7 The filtered water is mixed with the dry chemical to produce a microbial deactivated fluid; (3) the microbial deactivated fluid is circulated through the fluid circulation system and the filtration system, wherein a portion of the microbial deactivated fluid is directed through a fluid supply line and directing another portion through the first and second filter elements; (4) evacuating the reprocessor after a predetermined exposure time; (5) passing the wash water through the first and second filters The component is to fill the refilling processor with the cleaning water; and (6) to heat the cleaning water before the cleaning water enters the inner chamber. According to another embodiment of the present invention, there is provided a method of operating a reprocessor having a fluid circulation system for receiving an inner chamber of a microorganism deactivating article, for circulating a fluid therethrough, A device for producing a liquid disinfectant by mixing a drying chemical with water, and a water filtration system for filtering water entering the reprocessor. The water filtration system includes: a fluid supply line connected to a pressurized water source, first and second filter elements and heaters in the fluid supply line_line, the second filter element being downstream of the first filter element, and The heater is located downstream of the second filter element. A split line is connected to the fluid supply line to define a fluid passage that bypasses the first and second filter elements and the heater, and the water filtration system is coupled to the fluid circulation system. The steps of the method include: (1) filling the reprocessor with water by passing water from the water source through the first and second filter elements; (2) filtering through the first and second filter elements The subsequent water is mixed with a drying chemical to produce a liquid disinfectant; 9 200808387 (3) The liquid disinfectant is circulated through the fluid circulation system and the filtration system, wherein one part of the liquid disinfectant is directed through the fluid supply line and the other A portion is directed through the first and second filter elements to produce a filtered liquid sterilant; and (4) the heater is operated during the recycling step.
根據本發明之又一實施例，其提供一種再處理器，具 有循環系統以及水過濾系統，此循環系統將液態殺菌劑或 微生物去活性流體循環穿過構成循環係統一部分之内室， 而水過濾系統則過濾使用於再處理器中之水。此水過濾系 統包含構成循環系統之一部分的流體供應管線，且此流體 供應管線之一端與内室流體相通。方向閥位於流體供應管 線中，第一過濾元件則位於流體供應管線中，用以過濾流 過其中之流體，第二過濾元件亦位於流體供應管線中，用 以過濾流過其中之流體，此第二過濾元件乃位於第一過濾 70件與内室之間。水管線得連接至加壓水源，且連接至供 應管線上介於方向閥與第一過濾元件間之位置。分流管線 =接至流體供應管線，以定義繞過第一與第二過濾元件之 机體，道且分流官線之—端係連接至方向闊上游之流體 供應管線，而另-端騎接至第二過濾元件與内室間之流 古、、土根據本發明之又—實施例’其提供—錢作消毒器 此消毒器具有用以接納待消毒物品之内室、用以 =循環穿過内室之流體循環系統、用以藉 劑與水混合以產生液態消毒劑之裝置、以及用以過遽進 200808387 消毒器之水的水過濾系統。此水過濾系統包含連接至内室 之流體供應管線，配置於流體供應管線内之方向閥，於流 體供應管線中用以過濾流過其中之流體的第一過濾元件。 此第一過濾元件係位於方向閥下游之方向閥與内室間。第 二過濾元件位於流體供應管線中，用以過濾流過其中之流 體，且此第二過濾元件係位於第一過濾元件與内室之間。 水管線連接至流體供應管線上方向閥與第一過濾元件間之 父點，而分流管線則連接至流體供應管線以定義繞過方向 闕與第一與第二過濾元件之流體通道。此方法之步驟包含： (1) 藉由將來自水源之水穿過第一與第二過濾元件以 將消毒器注滿水； (2) 藉由將經由第一與第二過濾元件過濾後之水與乾 煉化學劑混合以產生液態消毒劑；以及 (3) 將液態消毒劑循環穿過該體循環系統以及過濾系 統，其中將液態消毒劑之一部分引導穿過第一與第 二過濾元件，且將另一部分引導穿過分流管線。 根據本發明之再一實施例，其提供一種檢查方法，於 再處理器中具有用以接納待微生物去活性或待消毒物品之 内室、用以將流體循環穿過内室之流體循環系統、用以藉 由將乾爍化學劑與水混合以產生微生物去活性流體之裝 置，以及用以過濾進入再處理器之水的水過濾系統。此水 過濾系統包含得連接至加壓水源之流體供應管線、第一與 弟一過;慮元件。此第一與第二過濾元件係位於流體供應管 線中，且第二過濾元件係位於第一過濾元件之下游，而此 200808387 檢查方法係檢查第一與第二過濾元件兩者中的至少一個， 其步驟包含： (1) 於第一或第二過濾元件之上游侧建立第一已知壓 力； (2) 讓第一或第二過濾元件之上游側上的壓力透過第 一或第二過濾元件以及透過已知大小之漏孔消散： (3) 監控一段時間後第一或第二過濾元件上游侧上之 壓力變化； (4) 於第一或第二過濾元件之上游侧建立第二已知壓 力； (5) 讓第一或第二過濾元件上游侧上之壓力透過第一 或第二過濾元件消散； (6) 監控一段時間後第一或第二過濾元件上游侧上之 壓力變化；以及 (7) 依據步驟（3)與步驟（6)所得之壓力變化來判定穿過 弟一或第二過滤元件之流動率。 本發明之優點在於提供一種用於再處理系統中 毒水過濾系統。 本發明之優點在於提供一種用於微生物去活性系統之 經微生物地去活性的過濾系統。 本發明之優點在於提供一種如上所述之過濾系統，降 低供應水因過濾元件中產生之微生物而受微生物污染之可 能性。 ^ 本發明之另一優點在於上述之過濾系統能夠高度確保 12 200808387 供應自第二過濾元件下游之水均已經過微生物地去活性或 消毒。 本發明之上述或其他特點將透過下述實施例之說明與 圖式及隨附之請求項而更為清楚明暸。 【實施方式】 請參照圖式，所有圖式均僅用於呈現本發明之各個實 施例，而非用於限縮本發明之範圍。第一圖為微生物去活 性設備ίο於簡化後之概要管線圖，其呈現本發明之較佳實 •施例。 外殼結構（未呈現於圖中）中之一部分的面板（panel ) 22定義一個凹陷處（recess或cavity ) 24，用以接收待微 生物地去活性的物品。於呈現之實施例中，並提供有托盤 或容器（container ) 26以接納去活性之儀器或設備，而容 器26之大小可容納於凹陷處24内，如第一圖所示。 手動之蓋子（lid) 32可移動於容許存取凹陷處24的 • 開啟位置以及關閉或掩蓋凹陷處24的關閉位置之間。密封 元件（seal element) 34圍繞凹陷處24以形成蓋子32與面 板22間的流體密封，亦即氣體與液體密封。栓裝置（latch means;未呈現於圖中）則用以在去活性循環時將蓋子32固 定於關閉之位置，而當蓋子32位於關閉位置時，凹陷處 24基本上將定義内室（ chamber) 36。 流體循環系統（fluid circulation system ) 40將微生物 去活性流體提供至内室36,並進一步將此微生物流體循環 穿過内室36。流體循環系統40包含連接至已加熱水源（未 13 200808387 呈現於圖中）之進水管線（water inlet line) 42，並於進水 管線42中提供一對過濾元件44、46以過濾可能存在於流 入之水中的較大污染物。過濾器44、46為大小排除過滤元 件（size exclusion filter element )，可將特定大小之微粒移 除。過濾元件46最好能夠過濾較過濾元件48所能過濾、者 小之微粒，且過濾元件44最好將大約3微米或更大之之微 粒移除，而過濾元件46則最好將大約0.1微米或更大之微 粒移除。並可提供壓力感測器（未呈現於圖中）以監控穿 過過濾元件44、46之壓力下降，此穿過過濾元件之壓力下 降變化將可用以指示阻塞或破裂等等。基本上，過濾元件 44、46係用以將用於供應設備10之水源中所發現之微粒 濾除。 此外，最好於進水管線42中提供用以將水源中的有 機體去活性的病毒抑制裝置（viral reduction device ) 52， 此病毒抑制裝置可為紫外線處理裝置，並且最好為 • NSF/ANSI標準55所定義之A級裝置或均等物，然而仍可 採用其他病毒抑制裝置。在本發明之較佳實施例中，將使 用美國北卡羅來納州夏洛特市之Wedeco Ideal Horzion所 生產的紫外線系統，其具有40,000 pW/cm2之最小劑量。 在呈現之實施例中，病毒抑制裝置52乃位於過濾、元件44、 46之下游，然而其亦可位於過濾元件44、46之上游。 水閥（water valve ) 54控制自進水管線42至系統供 應管線（system feeder line ) 62之水流，系統供應管線62 包含過濾、系統（filtration system ) 100，將自進入之水中濾 200808387 除極微小之有機體與微粒，以將經過微生物地去活性或消 毒之水提供至流體循環系統40。系統供應管線62將分支 為第一分支供應管線（first branch feeder line ) 64以及第 二分支供應管線66。第一分支管線64與内室36内之容器 26相通，而第二分支供應管線66則連接至内室36本身。 辅助分支管線（secondary branch feeder line ) 68係分流自 第一分支供應管線64,並且被引導至化學物傳送分發容器 (chemical delivery dispensing container) 72，化學物傳送 分發容器7 2包含有乾燥化學劑，當其雨水混合時，將可產 生用於消毒系統之抗菌流體。閥74控制穿過第一分支供應 管線64與穿過辅助分支供應管線68至化學物分發容器72 之水流，化學物分發容器72係配至於形成在外殼之面板 22内的牆76之内。於第二分支供應管線66以及輔助分支 供應管線68内的流動限制器（flow restrictor) 78可調整 流過其中之水流。 肇 分支返回管線（branch return line ) 82延伸自化學物 分發容器72，並連接至系統返回管線88 ( system return line)。同樣地，分支流體返回管線84、86乃個別延伸自 容器26與内室36，並連接至系統返回管線88。系統返回 管線88復與進水管線42與系統供應管線62相連，如第一 圖所示。泵（pump ) 92係位於系統返回管線88中，用以 將流體循環穿過流體循環系統40,而排水管線（drain line) 94則連接至系統返回管線88，且排水閥（drain valve) 96 控制流至排水管線94之水流。 15 200808387 請參照第二圖，其中呈現水過濾系統1 〇〇。水過渡系 統100係位於流體供應管線62中，並包含兩個過濾元件 (filter element) 114與134，分別呈現為過濾、組件（filter assembly ) 110、130之一部分。過濾元件114、134係串連 配置於流體供應管線62中。流體供應管線62的第一區段 62a使進水管線42與第一過濾組件110的入口側相通，其 第二區段62b則將第一過濾組件110的出口侧連接至第二 過濾組件130的入口侧，且其第三區段62c並將第二過濾 組件130的出口侧連接至加熱器（heater) 102，如第二圖 所示。加熱器102能夠將流過流體供應管線62第三區段 62c之水加熱到至少攝氏95度。 第一過濾組件110包含外殼112以及内部過濾元件 114。過濾元件114係為細菌保持大小排除過濾器（bacterial retentive size exclusion filter )，最好可將通常為 0· 12 微米 或更大之分支桿菌微粒濾除。過濾元件114可包含圓筒形 支樓層（cylindrical support layer )，例如聚丙烯 (polypropylene )，即過濾膜所圍繞之同型聚合物，例如聚 氟化亞乙烯（PVDF)或聚醚颯（PES)膜。過濾膜之形式 可為毛細管（capillary tube )或中空纖維膜（hollow fiber memver;或纖維），或者亦可為形成在平坦大支撐（tabular macroporous support)之内部或外部表面上之膜的平坦鞘 (tabular sheath )、或者薄片或薄膜（laminte sheet or film )、或者位於多孔支# ( porous support)上之薄膜。美 國加州得奥斯納市之PTI科技公司提供有適合之過濾器。 200808387 過濾、元件114定義環狀外室116以及内室118，外室 116代表過濾、元件114之上游、未過滤侧，而過濾組件之 内至118則代表過濾几件J14之下游、已過滤側。如圖所 示，流體供應管線62之第一區段62a係與第-過濾組件 U0之外室116相通，且供應管線62之第二區段62b乃與 第一過濾組件110之内室118相通。排水管線122則與第 二過濾組件110之外室116相通，而閥124則配置於排水 φ笞線122内以凋整自第一過濾組件Π 0至排水口的水流。 第二過濾組件130包含外殼132以及内部過濾元件 134,過濾元件134係為細菌保持大小排除過濾器，最好可 將通常為0.12微米或更大之分支桿菌微粒濾除。過濾元件 134可包含圓筒形支撐層，例如聚丙烯，即過濾膜所圍繞 之同i水&物，例如聚氟化亞乙烯或聚醚颯膜。過濾膜之 形式可為毛細管或中空纖維膜（或纖維），或者亦可為形成 在平坦大孔支撐之内部或外部表面上之膜的平坦鞘、或者 •薄片或薄膜、或者位於多孔支撐上之薄膜。美國加州得奥 斯納市之PTI科技公司提供有適合之過濾器。過濾元件13#4 定義環狀外室136以及内室138,外室136代表過渡元件 134之上游、未過濾侧，而過濾組件之内室則代表過 濾元件134之下游、已過濾侧。如圖所示，流體供應管線 62之弟一區段62b係與弟二過；慮組件130之外室136相 通’且供應管線62之第三區段62c乃與第二過濾組件13〇 之内室138相通。排水管線142則與第二過濾組件13〇之 外室136相通，而閥144則配置於排水管線142内以調整 17 200808387 自弟一過濾組件13 〇至排水口的水流。 第一與第二過濾組件Π0、130兩者最好於安裝前均 事先消毒或微生物地去活性，以使過濾組件1丨〇、丨之内 谷已無微生物污染物。如下文中將詳述，過滤組件1 1 〇、 130在每一次接續之處理階段中均將被微生物地去活性或 消毒。 弟對閥1、154係配置於流體供應管線62内以隔 離第一過濾組件110。在此情形下，閥152係配置於第一 過濾組件110入口侧之流體供應管線62的第一區段62a 内，而閥154則配置於第一過濾組件丨丨〇之出口侧的供應 管線區段62b内。同樣地，第二對閥ι62、164係提供於流 體供應管線62中以隔離第二過濾、組件13 q，在此情形下， 閥162係位於第二過濾組件130之入口侧的流體供應管線 區段62b中，而閥164則位於第二過濾組件j之出口侧 的流體供應管線區段62c中。 過濾器分流管線（bypass line) 172與流體供應管線 62相通於第一與第二過濾組件11〇、13〇之相對侧，具體 言之，分流管線172之一端連接至流體供應管線上介於泵 92以及進水管線42連接置流體供應管線a的位置之間。 方向確認閥（directional check valve ) 174係位於進水管線 42與過;慮器分流管線172之間以避免進入之水與過滤、器分 流管線172相通，其將詳述於下文之中。過濾器分流管線 172之另一端則與供應管線162的過濾組件1丨〇、1 go以及 加熱器102之外相通。 18 200808387 根據本發明之另一實施例，其提供一種過濾器淨化歧 管系統（filter purge manifold system ) i 80。過濾淨化管系 統180包合進氣官線182，用以提供乾淨且過濾後之加壓 氣體進入循環系統40。控制閥184位於進氣管線182内， 以調整穿過其中之氣流，而進氣管線182中的氣體最好處 於預設、調整後之壓力。在此情形下，進氣管線182可包 含壓力調整器（未呈現於圖中）以使進氣管線182内維持 #大，上不變之預期氣壓。進氣管線182分流為兩個分流返 回官線192、194，而具有控制閥189之排氣孔管線（vem line) 188則連接至分流返回管線192、194，如第二圖所 示。排氣孔管線188係用以於注入階段時讓氣體自水過濾 系統100中釋出，此將詳述於下文之中。 弟一分流管線192延伸穿過第一過濾組件11 〇之外殼 112，並與第一過濾組件no之外室116相通，而第一分流 管線192中的控制閥196將規制流過其中之氣流。第二分 _ 流管線194延伸穿過第二過濾組件130之外殼132，並與 第二過濾組件130之外室136相通，而控制閥丨98則配置 於分流管線194内以調整穿過其中之流動。 第一壓力感測器202係跨越系統供應管線62之第一 區段62a以及分流管線192，以感測過濾組件114之上游 側的壓力。 弟一壓力感测斋204係跨越系統供應管線62的第-區段62b以及分流管線194，以感測過濾組件134上游侧 的壓力。 200808387 第一漏孔管線（leak orifice une) 212係連接至流體 供應官線62的第一區段62a上進水管線54與第一過濾組 件no上游侧上的閥152之間。漏孔管線212内的閥 調整穿過其中的流動，而位於漏孔管線212中的流動限制 器215則調整穿過其中之流動。 系、、先微處理器（未呈現於圖中）控制循環系統4 〇以 及其中之閥的運作，其將詳述於下文之中。循環系統 _之運作包含主入階段、化學物產生與暴露階段、排放階段、 一個或以上之清洗階段以及過濾器檢查階段，其將詳述於 下文中。 以下將參照設備10以及水過濾系統1〇〇之運作以進 一步說明本發明之内容。將待微生物地去活性或消毒之一 個或以上的物品，例如醫療、牙醫、藥學、獸醫或喪葬儀 器或設備，裴載在内室36,在本呈現之實施例中，此物品 將裝載於容器26内，而接著將容器26置於内室％，且物 •品於内室36或容器26内可為托盤、藍子、卡式盒等（未 呈現於圖式中）所支撐。 、物品係藉由微生物去活性流體而被微生物地去活性 或消毒，例如過乙酸溶液’於本發明之某一實施例中，此 流體係將化學物配發容器72中的乾燥化學劑與水暴露、混 :所產生。在此情形下’於去活性或殺菌運作開始時，循 環系統40之排水閥96係為關閉狀態’而進水管線42之水 伐54則為開啟狀態，讓加熱後的水進入循環系統4〇。首 先如上所述以進水管線42中的㈣元件料、私過滤進入 20 200808387 之水，以濾除特定大小之微粒，且過濾元件44、46將接續 濾除更小之微粒。接著以病毒抑制裝置52處理進入之水， 即施加紫外線於水以使其中之有機體去活性。進入之水穿 過閥54並進入循環系統40，隨後以供應管線62中的過濾 組件110、130過濾進入之水，並繼續注入循環系統40、 内室36以及容器26。 介於進水閥54與過濾器分流管線172之間的確認閥 馨 174將使所有進入之水流過第一與第二過濾組件11()、 130，以確保過濾後之水進入設備10。 外部裝置使進入之水處於加壓狀態，以將流體循環系 統40、内至36以及谷器26中的氣體逼至溢流/氣體裝置 (未呈現於圖中），其通常位於儀器1〇的最高點，如此一 來系統内的氣體將移動至溢流裝置。 若出現有水穿過涵流區塊便表示儀器1 〇已注滿水， 糸統控制器接者便關閉水闕5 4，使水停止進入儀哭1 〇，亦 ⑩即停止進入流體循環系統40、内室36以及容器26，以上 說明基本上描述儀器10的水注入階段。 一旦注滿儀器10,系統控制器便開始產生與暴露階段 之運作，其中其驅動泵92以將水循環穿過流體循環系統 40、内室36以及容器26。在第一分支供應管線64内的 閥74將開啟以製造穿過化學物配發容器72之水流，於化 學物配發容器72内的水以及乾燥化學劑將形成微生物去 活性流體，如上所述，在本發明的某一實施例中，此流體 乃為過乙酸。以乾燥化學劑製成之去活性流體將流入循環 21 200808387 系統40 ’其將藉由果92而循環穿過循環系統40、内室36 以及谷器26。在此情形下，如圖所示，微生物去活性或消 毒流體的一部分將流入内室36圍繞容器26，且另一部分 將流入並穿過容器26以及包含於其中的物品。 如第一圖的箭頭所示，被循環的去活性流體的一部分 將牙過過慮器分流管線172，而其另一部分將穿過供應管 線62並穿過過濾組件11〇、13〇。配置於過濾器分流管線 172或/爪體供應管線内的調签閥（reguiating 可控制流過系統各個部分之流量，而去活性流體的主要部 分最好流過過濾器分流管線172。 去活性流體中穿過過濾器供應管線62與穿過第一與 第一過濾組件110、130之部分最好如此以確保過濾元件 114 134藉由暴露於去活性流體而達成去活性。在此情形 下，抓過過濾組件11〇、13〇之去活性流體將使過濾元件 114、134被微生物地去活性或消毒，並使於進水階段時可 能已進入過濾組件11〇、13〇之任何微生物污染物去活性。 據此，於儀器ίο的每一個運作階段中，過濾組件114、134 均暴露於微生物去活性或消毒流體以使其本身被微生物地 去T性或消毒。再者，在去活性階段中流過整個封閉迴路 之流體循環系統的微生物去活性流體將有效地使流體循環 系、、先40以及开》成此系統之元件與管線徹底地消毒，換言 之’將於每-個消毒循環中徹底地消毒流體循環系統。 在預设之暴露期間過後，便開始排放階段，排水閥％ 將開啟’而微生物去活性流體將自尋還系、统4〇、内室％ 22 200808387 以及容器26中排放。 在微生物去活性流體自設備1〇排放後，將進行一個 或更多之清洗階段以清除任何殘餘之微生物去活性流體以 及來自被去活性物品之任何殘餘物。在此情形下，將開啟 入口闕54以上述注入階段所述之方式將清潔之水導入儀 器10 ’而所有穿過水過濾系統丨〇〇進入循環系統與内 室36的水分將進行微生物地去活性或消毒。於每次清洗注 滿後，便將清洗用水自儀器10中排放，且在每次注入、循 環與排放階段中，流體溢流/氣體構成組件將運作以避免微 生物污染物進入系統的内部環境中。 於清洗階段後，將針對第一與第二過濾組件11〇、13〇 進行健全度測試以確保第一與第二過濾組件兩者正常運 作’具體言之則為過濾元件114、134。於進行過渡器健全 度測試前，最好先關閉閥152、154、164使過濾組件11〇、 130與過濾系統1〇〇隔離並彼此隔離，接著開啟個別位於 Φ 排放管線122、142、232與236中的閥124、144、234與 238 ’而讓過濾器外殼112、132排空。此外並開啟閥189、 196與198 ’使排放氣體進入過濾、器外殼η]、132，以促 使其排空。應可理解者為，進入之氣體將由過濾裝置予以 過濾以避免污染物進入過濾組件Π0、13〇。當過濾組件排 空後，便關閉排水閥124、144與排放閥189。 接著檢測水過濾系統100是否有任何洩漏以確保漏 孔212、216並未被阻塞，在此情形下，每一個過濾器組件 110、130以及與其相關聯之連接將定義一個「測試區域」。 23 200808387 基本上，第一過濾組件之「測試區域」係由過濾組件11〇 以及閥54、124、154、196與234之間的管線或管路連接 所定義。相似地，第二過濾組件130之「測試區域」則由 過濾組件130以及閥154、144、238、164與198之間的管 線或管路連接所定義。為進行洩露測試，閥54、154與164 將保持關閉以使第一與第二過濾組件1〇〇、13〇彼此互相隔 絕’並與流體擔j衣糸統4 0隔絕。管線12 2、14 2、2 3 2叙 _ 236中的閥124、144、234與238亦個別關閉以使任何出 口個別與過濾器外殼122、132隔離。閥152、162係位於 開啟位置，閥196與198初始時則為關閉，且空氣入口管 線182中的閥184將隨後開啟。如上所述，空氣入口管線 182中的氣壓將保持在設定之壓力等級。位於分流管線 192、194中的閥196、198接著將個別地開啟以將「測試 區域」暴露於設定壓力。一旦各別測試區域中的壓力趨於 穩定，便關閉閥196、198以使各別測試區域與空氣入口管 _ 線182隔離。壓力差感測器202、204將比較測試區域内的 壓力與空氣入口管線182内的設定壓力，若測試壓力區域 内沒有洩漏，則第一與第二壓力差感測器202、204便不應 感測到壓力差異’不存在壓力變化表示過渡器外殼1 1 2、 132或與其相關連之測試區域沒有洩漏。於漏孔管線212、 216中的閥214、218接著將開啟以允許「設定壓力」自各 別測試壓力區域中洩漏或釋放。第一與第二壓力差感測器 202、204將感測各別測試壓力區域與空氣入口管線182内 的設定壓力間壓力差的變化，此壓力變化表示漏孔212、 24 200808387 216並未被阻塞，而測試區域與空氣入口管線182中設定 壓力間沒有壓力差變化則表示測試區域内的漏孔已堵塞。 在前述測試以判定測試區域是否健全與漏孔是否正 常運作後，便接著進行水過濾器健全度測試。根據本發明 之實施例’此過渡器健全度測試包含兩個階段，在此情形 下，閥54、154以及164均關閉以使第一及第二過濾組件 Π〇、130與流體循環系統40隔離，並彼此互相隔離。閥 馨 152、162處於開啟位置，而排放管線122、142、232、236 中的閥124、144、234、238則為關閉，且漏孔管線212、 216中的閥214、218亦為關閉。 接著開啟空氣入口 182中的闕184以讓加壓氣體進入 分支管線192、194，如上所述，空氣入口管線182中的氣 壓係保持再設定壓力之水準。隨後開啟供應管線192、194 中的閥196、198以使加壓氣體進入與每一個過濾組件 110、13 0相關聯之各個測試區域。在預設之時間過後，各 _ 別測試區域中的壓力將穩定處於上述設定壓力水準，此時 便關閉閥196、198。 隨著各別測試區域内的壓力穩定於「設定壓力」，將 開啟個別於排放管線232、236中的閥234、238以及漏孔 管線212、216中的閥214、218。應可理解者為，將有壓 力差存在於跨過過濾元件114、134以及穿過漏孔管線 212、216中流體限制器215、219。換言之，由於閥234、 238將内室118、138連接至排放口，過濾組件110、130 之内室118、138中所存在之壓力將較小，而相似地，由於 25 200808387 漏孔管線連接器大氣，因此將於流體限制器215、219之外 建構較低之壓力。外室116、136内的高壓將穿過過濾元件 114、134且穿過漏孔管線212、216之流體限制器215、219 慢慢逸散，壓差感測器202、204則感測内室118、138以 及管線182中的設定壓力水準間的壓力差距。系統控制器 監控一段時間之壓力差異，並決定每一個別測試區域每單 位時間之壓力下降Qsys，此Qsys為穿過過濾元件n4、134 以及漏孔管線112、Π 6逸散所造成之每單位時間壓力下降 值。測量穿過過濾元件114、134以及穿過漏孔管線212、 216之壓力變化率便為兩階段過濾器檢測中的第一個階 段。 與完成第一階段後，便關閉漏孔管線212、216中的 閥214、218以及排放管線232、236中的閥234、238。接 著開啟閥196、198，為過濾組建11 〇、13〇於個別測試區 域中再次建構設定壓力水準，隨後並關閉閥196、198。接 • 著開啟排放管線232、236中的閥234、238，此時漏孔管 線212、216中的閥214、218仍保持關閉。當壓力穿過過 濾元件114、134逸散時，系統控制器將監控壓差傳感器 (differential pressure transducer ) 202、204 於一段時間中 所感測之壓差變化。在此情形下，過濾器確認程序的第二 階段重複第一階段，惟關閉漏孔。系統控制器監控一段時 間内之壓力差變化，並決定每一個別測試區域每單位時間 之壓力下降Qfilter ’此Qfnter為僅穿過過濾元件之壓力逸散 所造成的每單位時間之壓力下降值。 26 200808387 藉由上述所得之資料，系統控制器將判定壓力變化是 否表示穿過過濾元件114、134之流動為適當，在此情形 下，系統控制器判定Qsys與Q肋』的差距，此差距代表 ，漏孔之每單位時間的壓力T降值QQdf。系統控制器接著 藉由將Q^if除以Qcal來判定每一體積之單位壓力值cal， 其中Qcal漏孔於預期測試即設定壓力時的標準化容積流動 率（calibrated V〇lumetric flow 論）。此 CAL 值係為漏孔 _之容積流動率以及對系統所造成、單位為每一體積壓力的 對應壓力下降間之關係。隨後藉由將Qswf除以CAL以判 定個別水過濾元件之計算而得的流體擴散率，此計算 而得之值為基於過濾器壓力下降以及漏孔之過濾器的計算 而得之流體擴散率。不正常的壓力變化則表示過濾元件 114、134中存有瑕疵，進而代表需要更換過濾組件u〇或 過濾組件130,並且設備1〇並未進行消毒或微生物地去活 性運作。在此情形下，過濾元件114或過濾元件134之故 ⑩障表示水尚未被過濾至預期之水準，並且被污染的水可能 已進入内室36。惟縱然兩個過濾元件114、134中的一個 相信已足以提供充分之過濾來確保水之微生物地去活性或 消毒，設備10於其僅偵測到一個過濾元件有瑕疵時，最好 仍指示運作存有瑕疵。 雖然上述§兒明中戌漏測試、漏孔健全度測試以及過濾 器健全度測試三者係同步進行，但這些對於個別過濾組件 Π0、130以及相關聯之測試區域的測試亦可獨立進行。 本發明因此提供一種水過濾系統1〇〇，以供使用於消 27 200808387 毒或微生物去活性再處理器中，降低微生物污染物等類似 物隨著水進入内室36。 請參照第三圖，其中呈現本發明另一實施例的水過濾 系統1〇〇。基本上，第三圖呈現之分流系統（bypass system) 30Ό允許於處理階段中繞過第二過濾組件i3〇。在此情形 下，微生物去活性流體相信能夠使某些過濾元件降低品 質’使其水淨化效能變差。舉例而言，微生物去活性流體 _ 中的介面活性劑可使過濾器阻塞，尤其是當過濾器之孔徑 極小時。據此，最好能夠限制第二過濾組件〗3()暴露於去 活性流體之機會。於呈現之實施例中，分流管線3〇2之一 端係連接至流體供應管線62之第二區段62b，且其另一端 連接至流體供應管線62之第三區段62c。閥304控制穿過 为流官線302之流動’而閥304通常係關閉，以當流體流 穿第二過濾組件130時阻擋流體穿過分流管線302。藉由 關閉閥162、164以及開啟分流管線302中的閥304第二過 ⑩濾組件130將可繞過第二過濾組件130，因而使流體流動 穿過流體供應管線以繞過第二過濾組件130。於微生物去 活性流體產生與循環階段時，第三圖中的實施例係由系統 控制器所控制運作，以避免去活性流體流穿第二過渡組件 130。於水進入階段或清洗階段時，控制器將控制個別之閥 304、162、164，以允許進入之水流穿第二過濾組件，而於 每一個注水或清洗階段提供已消毒或已微生物地去活性的 水。 請參照第四圖，其中呈現水過濾、系統1 〇〇的另一個實 28 200808387 施例，且其具有單一過濾組件410。過濾組件41〇包含外 殼412以及兩個外部過濾元件414、416。過渡元件414與 416兩者均為細菌保持大小排除過濾器，最好將通常為 0.12微米或更大之分支桿菌滤除。過濾元件414、am可 包含圓桶狀支撐層（未呈現於圖中），例如聚氟化亞乙烯或 聚醚颯膜。過濾膜之形式可為毛細管或中空纖維膜（或纖 維）’或者亦可為形成在平坦大孔支撐之内部或外部表面上 之膜的平坦鞘、或者薄片或薄膜、或者位於多孔支撐上之 薄膜。環狀外室422係被定義於外部過濾元件414以及外 殼412之間，中間室424則被定義於外部過濾元件414以 及内部過濾、元件416之間，而内室426係由過滤元件416 所定義。如第四圖所示，過濾組件41〇係配置於系統供應 管線62中，排放管線142與外室422相通，且排放管線 235則與内室426相通。 如第四圖之前頭所示，流穿系統供應管線162之流體 _首先牙過外部過濾兀件414，並接著穿過内室416。在此情 形下’内部過濾斋416係為外部過濾元件414之下游管線。 據此，過滤組件4H)與第二圖所示之實施例提供相同之過 遽效果，然而單-過滤組件41〇降低水過滤系统1〇〇之闕 以及連接的數目，因而增加其可靠性與效能。除了簡化整 體結構、減少過據器g並降低連接管線之數目外，循環系 統4G之整體體積亦降低’目而亦降低系統内所需之液態化 子作用數里。亦可理解者為前述之鴻漏測試、漏孔健全度 測試以及過遽器健全度測試同樣可進行於過滤組件41〇及 29 200808387 其相關「測試區域」之上。 上述内容為本發明之特定實施例，應可理解者為此實 施例僅為忒明之用，且具有本發明所屬領域中具有通常知 識者應可在未背離本發明之精神與範圍下，進行各種變換 與調整。 ' 根據本發明之另一實施例，於流體供應管線62之第 三區段62c中的加熱器1〇2係用以將流穿區段6仏之水加 ⑩，至足以使經過第一與第二過濾組件11〇、130之水中的病 =去活性之溫度。如上所述，最好為紫外線處理裝置的病 毒抑制裝置52將處理進入之水以使其中之友機體去活 性，而加熱器102則作為第二病毒抑制裝置，與病毒抑制 裝置52共同作用，或甚至取代之。在此情形下，加熱器 亦處理進入之水以使其中之有機體去活性。於本發明 之二％例中，係藉由加熱器1〇2將流穿流體供應管線W 之第三區段62c之水加熱至大約攝氏40度至攝氏95度之 ⑩5。於本發明的另—個實施例中，係將流穿流體供應管線 62之第三區段62c的水加熱至大約攝氏55度至攝氏85度 之間。於本發明之較佳實施例中，最好將水加熱至大約攝 氏75度至攝氏85度之間。 圭 #、、、σσ 1们隶好僅於消毒循環中的清洗階段時作為病 =抑制裝置’在此情形下，於注水階段時進人循環系統仙 :及内室36的水，係因於循環系統4〇之運作的化學物產 生與暴露階段時，將消毒化學物自化學物傳送分發容器72 導入水中，被微生物地殺菌或消毒。據此，存在於設備ι〇 200808387 中水之内的任何病毒汗染物均將藉由化學物而使其去活 性。因為未將任何去活性化學物或㈣劑導入清洗用水 中L所以乃利用加熱器102於清洗階段時，在水進入内室 36則、經第一與第二過爐組件11〇、13〇過滤後，使任何 可能存在於水中的細菌去活性。是以，便得進一步確保内 室36内之儀器設備的消毒狀態。 、加熱器102最好用以於消毒循環之清洗階段中使細菌 ⑩去活陡，應可理解者為加熱器102亦可用以於化學物產生 與暴露階段巾加熱以内室％的水。在此情形τ，係藉由 於運作循環之化學物產生與暴露階段中加熱此化學物，以 強化化學物傳送分發容器72戶斤導入之化學物的消毒特性。 加熱器10 2亦能夠用以於去活性階段中當流體循環穿 過流體循環系統40時，加熱此穿過流體循環系統4〇 體。 机 本案應包含所有未偏離本案請求項及與其均等者之 •範圍的所有調整與變化。 【圖式簡單說明】 第一圖為微生物去活性系統之概要圖。 第二圖為過濾系統之概要圖，描述本發明之一個實施 例。 、 弟二圖為呈現於弟二圖中之過濾系統的局部圖，其呈 現另一個實施例。 ^ 弟四圖為過濾、糸統之概要圖，其呈現本發明之另一 施例。 31 200808387 【主要元件符號說明】 42 進水管線（water inlet line ) 54 水閥（water valve ) 62 系統供應管線 (system feeder line) 62a第一區段 62b第二區段 62c第三區段 88 系統返回管線 (system return line) 92 泵（pump) 100 過濾系統（filtration system ) 102 加熱器（heater) 110第一過濾組件（first filter assembly ) 112外殼 114過濾元件（filter element) 116環狀外室 118内室 122排水管線 124閥 130第二過濾組件 132外殼 134過濾元件 136環狀外室 138内室 142排水管線 144閥 152閥 154閥 162閥 164閥 172分流管線（bypass line ) 174方向確認閥 (directional check valve ) 180過濾器淨化歧管系統 (filter purge manifold system) 182進氣管線 184控制閥 188排氣孔管線（vent line ) 32 200808387 189控制閥 192分流返回管線 194分流返回管線 196控制閥 198控制閥 202第一壓力感測器 204第二壓力感測器 212第一漏孔管線（leak orifice line ) 214閥 215流動限制器 216漏孔管線 218閥 219流動限制器 222 調整閥（regulating valve ) 232排放管線 234閥 236排放管線 238閥 33According to still another embodiment of the present invention, there is provided a reprocessor having a circulation system and a water filtration system that circulates a liquid sterilizing agent or a microorganism deactivating fluid through an inner chamber constituting a part of the circulation system, and water filtration The system filters the water used in the reprocessor. The water filtration system includes a fluid supply line that forms part of the circulation system, and one end of the fluid supply line is in fluid communication with the internal chamber. The directional valve is located in the fluid supply line, the first filter element is located in the fluid supply line for filtering the fluid flowing therethrough, and the second filter element is also located in the fluid supply line for filtering the fluid flowing therethrough. The two filter elements are located between the first filter 70 and the inner chamber. The water line is connected to a source of pressurized water and is connected to the supply line at a location between the directional valve and the first filter element. a split line = connected to the fluid supply line to define a body bypassing the first and second filter elements, and the end of the split flow line is connected to the fluid supply line in the direction of the upstream, and the other end is coupled to Between the second filter element and the inner chamber, the soil is further provided according to the present invention - the embodiment provides a sterilizer for sterilizing the inner chamber of the article to be sterilized, for circulating through A fluid circulation system for the chamber, a device for mixing the mixture with water to produce a liquid disinfectant, and a water filtration system for plunging into the water of the 200808387 sterilizer. The water filtration system includes a fluid supply line connected to the inner chamber, a directional valve disposed within the fluid supply line, and a first filter element in the fluid supply line for filtering fluid flowing therethrough. The first filter element is located between the directional valve and the inner chamber downstream of the directional valve. A second filter element is located in the fluid supply line for filtering fluid flowing therethrough, and the second filter element is located between the first filter element and the inner chamber. The water line is connected to the parent point between the directional valve on the fluid supply line and the first filter element, and the split line is connected to the fluid supply line to define a fluid passage that bypasses the direction 阙 and the first and second filter elements. The steps of the method comprise: (1) filling the sterilizer with water by passing water from the water source through the first and second filter elements; (2) filtering through the first and second filter elements Water is mixed with a dry chemical to produce a liquid disinfectant; and (3) a liquid disinfectant is circulated through the systemic circulation system and a filtration system, wherein a portion of the liquid disinfectant is directed through the first and second filter elements, and Guide another part through the split line. According to still another embodiment of the present invention, there is provided an inspection method having a fluid circulation system for receiving an inner chamber to be deactivated or to be sterilized, a fluid circulation system for circulating a fluid through the inner chamber, A device for producing a microbial deactivating fluid by mixing a dry chemical with water, and a water filtration system for filtering water entering the reprocessor. The water filtration system includes a fluid supply line that is connected to a source of pressurized water, the first and the younger; The first and second filter elements are located in the fluid supply line and the second filter element is located downstream of the first filter element, and the 200808387 inspection method checks at least one of the first and second filter elements, The steps include: (1) establishing a first known pressure on the upstream side of the first or second filter element; (2) passing pressure on the upstream side of the first or second filter element through the first or second filter element And dissipating through a leak of known size: (3) monitoring the pressure change on the upstream side of the first or second filter element after a period of time; (4) establishing a second known on the upstream side of the first or second filter element (5) allowing the pressure on the upstream side of the first or second filter element to dissipate through the first or second filter element; (6) monitoring the pressure change on the upstream side of the first or second filter element after a period of time; (7) The flow rate through the first or second filter element is determined according to the pressure change obtained in the step (3) and the step (6). It is an advantage of the present invention to provide a toxic water filtration system for use in a reprocessing system. It is an advantage of the present invention to provide a microbial deactivated filtration system for use in a microbial deactivation system. It is an advantage of the present invention to provide a filtration system as described above which reduces the likelihood of supply water being contaminated by microorganisms due to microorganisms produced in the filter element. Another advantage of the present invention is that the filtration system described above is highly capable of ensuring that 12 200808387 water supplied downstream of the second filter element has been microbially deactivated or sterilized. The above and other features of the present invention will become more apparent from the description and appended claims appended claims DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS All of the drawings are intended to represent various embodiments of the present invention, and are not intended to limit the scope of the present invention. The first figure is a simplified schematic diagram of a microbial deactivation apparatus, which presents a preferred embodiment of the present invention. A panel 22 of one of the outer casing structures (not shown) defines a recess (recess or cavity) 24 for receiving items to be biologically deactivated. In the presented embodiment, a tray or container 26 is provided to receive the deactivated instrument or device, and the container 26 is sized to fit within the recess 24, as shown in the first figure. A manual lid 32 is movable between an open position that allows access to the recess 24 and a closed position that closes or masks the recess 24. A seal element 34 surrounds the recess 24 to form a fluid seal between the cover 32 and the panel 22, i.e., the gas is sealed from the liquid. A latching means (not shown) is used to secure the lid 32 to the closed position during the deactivation cycle, and the recess 24 will substantially define the chamber when the lid 32 is in the closed position. 36. A fluid circulation system 40 provides the microbial deactivating fluid to the inner chamber 36 and further circulates the microbial fluid through the inner chamber 36. The fluid circulation system 40 includes a water inlet line 42 coupled to a source of heated water (not shown in FIG. 200808387) and provides a pair of filter elements 44, 46 in the inlet line 42 for filtration to be present in the Larger contaminants in the water flowing into. The filters 44, 46 are size exclusion filter elements that remove particles of a particular size. Filter element 46 is preferably capable of filtering particles that are smaller than filter element 48, and filter element 44 preferably removes particles of about 3 microns or greater, while filter element 46 preferably will be about 0. Microparticles of 1 micron or larger are removed. A pressure sensor (not shown) may be provided to monitor the pressure drop across the filter elements 44, 46, and this pressure drop across the filter element will be used to indicate blockage or cracking and the like. Basically, the filter elements 44, 46 are used to filter out particulates found in the water source used to supply the apparatus 10. Further, a virus reduction device 52 for deactivating the organism in the water source is preferably provided in the water inlet line 52, and the virus suppression device may be an ultraviolet treatment device, and preferably • NSF/ANSI standard Class A devices or equivalents as defined in 55, however other viral suppression devices may still be employed. In a preferred embodiment of the invention, an ultraviolet system produced by Wedeco Ideal Horzion of Charlotte, North Carolina, USA, having a minimum dose of 40,000 pW/cm2 will be used. In the embodiment presented, the virus suppression device 52 is located downstream of the filter, elements 44, 46, although it may also be located upstream of the filter elements 44,46. A water valve 54 controls the flow of water from the inlet line 42 to the system feeder line 62. The system supply line 62 contains a filtration system 100 which removes very small amounts of 200808387 from the incoming water. The organisms and particles provide water to the fluid circulation system 40 that is microbially deactivated or sterilized. The system supply line 62 will branch into a first branch feeder line 64 and a second branch supply line 66. The first branch line 64 is in communication with the container 26 in the inner chamber 36 and the second branch supply line 66 is connected to the inner chamber 36 itself. A secondary branch feeder line 68 is split from the first branch supply line 64 and directed to a chemical delivery dispensing container 72, which contains a drying chemical, When the rainwater is mixed, an antibacterial fluid for the disinfection system will be produced. Valve 74 controls the flow of water through first branch supply line 64 and through auxiliary branch supply line 68 to chemical dispensing container 72, which is fitted into wall 76 formed in panel 22 of the outer casing. A flow restrictor 78 in the second branch supply line 66 and the auxiliary branch supply line 68 regulates the flow of water therethrough. Bra A branch return line 82 extends from the chemical dispensing container 72 and is coupled to a system return line 88. Similarly, the branch fluid return lines 84, 86 extend individually from the vessel 26 and the inner chamber 36 and are coupled to the system return line 88. System return line 88 is reconnected with inlet line 42 and system supply line 62, as shown in the first figure. A pump 92 is located in system return line 88 for circulating fluid through fluid circulation system 40, and a drain line 94 is coupled to system return line 88 and drain valve 96 controls The flow of water to the drain line 94. 15 200808387 Please refer to the second figure, which presents the water filtration system 1 〇〇. The water transition system 100 is located in the fluid supply line 62 and includes two filter elements 114 and 134, each appearing as part of a filter, filter assembly 110, 130. The filter elements 114, 134 are arranged in series in the fluid supply line 62. The first section 62a of the fluid supply line 62 communicates the inlet line 42 with the inlet side of the first filter assembly 110, and the second section 62b connects the outlet side of the first filter assembly 110 to the second filter assembly 130. The inlet side, and its third section 62c, connects the outlet side of the second filter assembly 130 to a heater 102, as shown in the second figure. The heater 102 is capable of heating the water flowing through the third section 62c of the fluid supply line 62 to at least 95 degrees Celsius. The first filter assembly 110 includes a housing 112 and an internal filter element 114. The filter element 114 is a bacterial retentive size exclusion filter, preferably a mycobacterial particle of usually 0.12 micrometer or larger. The filter element 114 can comprise a cylindrical support layer, such as polypropylene, ie a homopolymer surrounded by a filter membrane, such as a polyvinylidene fluoride (PVDF) or polyether oxime (PES) membrane. . The filter membrane may be in the form of a capillary tube or a hollow fiber membrane (or fiber), or may be a flat sheath of a membrane formed on an inner or outer surface of a tabular macroporous support ( Tabular sheath ), or a laminte sheet or film, or a film on a porous support. PTI Technologies, Inc. of Osna, California, USA, has suitable filters. 200808387 Filter, element 114 defines an annular outer chamber 116 and an inner chamber 118, the outer chamber 116 represents the upstream of the filter, element 114, the unfiltered side, and the inside of the filter assembly to 118 represents the downstream of the filtered J14, filtered side . As shown, the first section 62a of the fluid supply line 62 communicates with the outer chamber 116 of the first filter assembly U0, and the second section 62b of the supply line 62 communicates with the inner chamber 118 of the first filter assembly 110. . The drain line 122 is in communication with the outer chamber 116 of the second filter assembly 110, and the valve 124 is disposed within the drain φ line 122 to deflate the flow of water from the first filter assembly Π 0 to the drain. The second filter assembly 130 includes a housing 132 and an internal filter element 134. The filter element 134 is a bacteria retention size exclusion filter, preferably 0. Mycobacterial microparticles of 12 microns or larger are filtered out. The filter element 134 can comprise a cylindrical support layer, such as polypropylene, i.e., the i-water & material surrounded by the filter membrane, such as a polyvinylidene fluoride or polyether ruthenium membrane. The filter membrane may be in the form of a capillary or hollow fiber membrane (or fiber), or may be a flat sheath of a membrane formed on the inner or outer surface of a flat macroporous support, or a sheet or film, or located on a porous support. film. PTI Technologies, Inc. of Osna, California, USA, has suitable filters. The filter element 13#4 defines an annular outer chamber 136 that represents the upstream, unfiltered side of the transition element 134 and an inner chamber 138 that represents the downstream, filtered side of the filter element 134. As shown, the section 62b of the fluid supply line 62 is the same as the second section; the chamber 136 is connected to the chamber 136 and the third section 62c of the supply line 62 is within the second filter assembly 13 Room 138 is in communication. The drain line 142 is in communication with the outer chamber 136 of the second filter assembly 13 and the valve 144 is disposed in the drain line 142 to adjust the flow of water from the filter assembly 13 to the drain. Preferably, both the first and second filter assemblies Π0, 130 are pre-sterilized or microbially deactivated prior to installation so that the filter assembly 1 has no microbial contaminants. As will be described in more detail below, the filter modules 1 1 , 130, will be microbially deactivated or sterilized during each successive processing stage. The valve pairs 1, 154 are disposed in the fluid supply line 62 to isolate the first filter assembly 110. In this case, the valve 152 is disposed in the first section 62a of the fluid supply line 62 on the inlet side of the first filter assembly 110, and the valve 154 is disposed in the supply line section on the outlet side of the first filter assembly Within section 62b. Likewise, a second pair of valves ι 62, 164 are provided in the fluid supply line 62 to isolate the second filter, assembly 13 q, in which case the valve 162 is located in the fluid supply line region on the inlet side of the second filter assembly 130. In section 62b, valve 164 is located in fluid supply line section 62c on the outlet side of second filter assembly j. A filter bypass line 172 is in communication with the fluid supply line 62 on opposite sides of the first and second filter assemblies 11A, 13A, in particular, one end of the split line 172 is connected to the fluid supply line between the pumps 92 and the inlet line 42 are connected between the positions of the fluid supply line a. A directional check valve 174 is located between the inlet line 42 and the bypass line 172 to prevent the incoming water from communicating with the filter, splitter line 172, which will be described in more detail below. The other end of the filter split line 172 is in communication with the filter assemblies 1A, 1go and the heater 102 of the supply line 162. 18 200808387 In accordance with another embodiment of the present invention, a filter purge manifold system i 80 is provided. The filter purge system 180 encloses an intake line 182 for providing clean and filtered pressurized gas to the circulation system 40. Control valve 184 is located within intake line 182 to regulate the flow of gas therethrough, while the gas in intake line 182 is preferably at a predetermined, adjusted pressure. In this case, the intake line 182 may include a pressure regulator (not shown) to maintain a desired, large, constant temperature within the intake line 182. Intake line 182 is split into two split return lines 192, 194, and a vent line 188 with control valve 189 is coupled to split return lines 192, 194, as shown in the second figure. A vent line 188 is used to allow gas to be released from the water filtration system 100 during the injection phase, as will be described in more detail below. A splitter line 192 extends through the outer casing 112 of the first filter assembly 11 and communicates with the outer chamber 116 of the first filter assembly no, and the control valve 196 in the first split line 192 regulates the flow of gas therethrough. The second sub-flow line 194 extends through the outer casing 132 of the second filter assembly 130 and communicates with the outer chamber 136 of the second filter assembly 130, and the control valve 98 is disposed within the split line 194 for adjustment therethrough. flow. The first pressure sensor 202 spans the first section 62a of the system supply line 62 and the split line 192 to sense the pressure on the upstream side of the filter assembly 114. The pressure-sensing sensing 204 spans the first section 62b of the system supply line 62 and the splitter line 194 to sense the pressure on the upstream side of the filter assembly 134. 200808387 A first leak line 214 is connected between the inlet section 54 on the first section 62a of the fluid supply line 62 and the valve 152 on the upstream side of the first filter assembly no. The valve within the leak line 212 adjusts the flow therethrough, while the flow restrictor 215 located in the leak line 212 adjusts the flow therethrough. The system, the first microprocessor (not shown) controls the operation of the circulatory system 4 and its valves, which will be described in more detail below. The operation of the circulatory system includes the main stage, the chemical production and exposure stage, the discharge stage, one or more cleaning stages, and the filter inspection stage, which will be described in detail below. The operation of the apparatus 10 and the water filtration system 1 will be described below to further explain the contents of the present invention. One or more items to be microbially deactivated or sterilized, such as medical, dental, pharmacy, veterinary or funeral apparatus or equipment, are carried in inner chamber 36, which in the presently illustrated embodiment will be loaded into the container Within 26, the container 26 is then placed in the inner chamber, and the contents are contained within the inner chamber 36 or container 26 for trays, blues, cassettes, etc. (not shown). The article is microbially deactivated or sterilized by a microbial deactivation fluid, such as a peracetic acid solution. In one embodiment of the invention, the fluid system dispenses the drying chemistry and water from the container 72. Exposure, mixing: produced. In this case, 'at the beginning of the deactivation or sterilization operation, the drain valve 96 of the circulation system 40 is in the closed state' and the water cut 54 of the inlet line 42 is in the open state, allowing the heated water to enter the circulation system. . First, the (4) component material in the water inlet line 42 is first filtered into the water of 20 200808387 to filter out particles of a specific size, and the filter elements 44, 46 will successively filter out smaller particles. The incoming water is then treated with a virus suppression device 52, i.e., ultraviolet light is applied to the water to deactivate the organism therein. The incoming water passes through valve 54 and into circulation system 40, whereupon the incoming water is filtered by filtration assemblies 110, 130 in supply line 62 and continues to be injected into circulation system 40, inner chamber 36, and vessel 26. A confirmation valve 174 between the inlet valve 54 and the filter split line 172 will cause all incoming water to flow through the first and second filter assemblies 11(), 130 to ensure that filtered water enters the apparatus 10. The external device places the incoming water in a pressurized state to force the gas in the fluid circulation system 40, the inner to 36, and the trough 26 to the overflow/gas device (not shown), which is typically located at the instrument 1 At the highest point, the gas in the system will move to the overflow. If there is water passing through the culvert block, it means that the instrument 1 is filled with water, and the system controller will close the water 阙 5 4, so that the water stops entering the instrument and cries for 1 〇, and 10 stops the fluid circulation system. 40. Inner chamber 36 and container 26, the above description substantially describes the water injection phase of instrument 10. Once the instrument 10 is filled, the system controller begins the operation of the exposure phase, where it drives the pump 92 to circulate water through the fluid circulation system 40, the inner chamber 36, and the container 26. The valve 74 in the first branch supply line 64 will open to create a flow of water through the chemical dispensing container 72. The water in the chemical dispensing container 72 and the drying chemical will form a microbial deactivated fluid, as described above. In one embodiment of the invention, the fluid is peracetic acid. The deactivated fluid made of dry chemical will flow into the cycle 21 200808387 system 40' which will circulate through the circulation system 40, the inner chamber 36 and the trough 26 by the fruit 92. In this case, as shown, a portion of the microbial deactivation or disinfecting fluid will flow into the inner chamber 36 around the container 26, and another portion will flow into and through the container 26 and the items contained therein. As indicated by the arrows in the first figure, a portion of the recycled reactive fluid will pass through the filter splitter line 172 while another portion will pass through the supply line 62 and through the filter assemblies 11A, 13A. A metering valve disposed in the filter split line 172 or the / claw supply line (reguiating controls the flow through various portions of the system, while the main portion of the deactivated fluid preferably flows through the filter split line 172. Deactivated fluid The passage through the filter supply line 62 and the passage through the first and first filter assemblies 110, 130 is preferably such as to ensure that the filter element 114 134 is deactivated by exposure to the deactivated fluid. In this case, The deactivated fluid passing through the filter assembly 11〇, 13〇 will microbe deactivate or sterilize the filter elements 114, 134 and may have entered any of the microbial contaminants of the filter assemblies 11〇, 13〇 during the influent stage. Accordingly, in each stage of operation of the instrument ίο, the filter assemblies 114, 134 are exposed to microbial deactivation or disinfecting fluid to cause themselves to be microbiologically sterilized or sterilized. Furthermore, in the deactivation phase The microbial deactivation fluid of the fluid circulation system throughout the closed loop will effectively circulate the fluid, first and foremost into the components and pipelines of the system. Disinfection, in other words 'completely disinfect the fluid circulation system in each disinfection cycle. After the preset exposure period, the discharge phase begins, the drain valve % will open' and the microbial deactivation fluid will self-seek 4〇, 室% 22 200808387 and discharge in container 26. After the microbial deactivating fluid is discharged from the equipment, one or more washing stages will be carried out to remove any residual microbial deactivated fluid and from the deactivated material. Any residue. In this case, the opening port 54 is opened to introduce clean water into the instrument 10' in the manner described above in the injection phase and all of the water passing through the water filtration system into the circulation system and the interior 36 Microbial deactivation or disinfection will be carried out. After each wash is filled, the wash water is drained from the instrument 10, and during each injection, cycle and discharge phase, the fluid overflow/gas constituent components will operate to avoid Microbial contaminants enter the internal environment of the system. After the cleaning stage, the first and second filter assemblies 11〇, 13〇 will be sounded. Testing to ensure that both the first and second filter assemblies are functioning properly - specifically filter elements 114, 134. It is preferred to close valves 152, 154, 164 to allow filter assembly 11 prior to performing the transitioner soundness test. 130 is isolated from and isolated from the filtration system 1 and then opens the valves 124, 144, 234 and 238' individually located in the Φ discharge lines 122, 142, 232 and 236 to empty the filter housings 112, 132. And the valves 189, 196 and 198' are opened to allow the exhaust gas to enter the filter, the housing η], 132 to cause it to vent. It should be understood that the incoming gas will be filtered by the filter to prevent contaminants from entering the filter assembly. 13〇. When the filter assembly is emptied, the drain valves 124, 144 and the drain valve 189 are closed. The water filtration system 100 is then tested for any leaks to ensure that the leaks 212, 216 are not blocked, in which case each filter assembly 110, 130 and its associated connection will define a "test area." 23 200808387 Basically, the "test area" of the first filter assembly is defined by the filter assembly 11A and the line or line connection between valves 54, 124, 154, 196 and 234. Similarly, the "test area" of the second filter assembly 130 is defined by the filter assembly 130 and the conduit or conduit connections between the valves 154, 144, 238, 164 and 198. For the leak test, the valves 54, 154 and 164 will remain closed to isolate the first and second filter assemblies 1 , 13 from each other and from the fluid. The valves 124, 144, 234 and 238 in lines 12 2, 14 2, 2 3 2 _ 236 are also individually closed to isolate any outlets from the filter housings 122, 132 individually. Valves 152, 162 are in the open position, valves 196 and 198 are initially closed, and valve 184 in air inlet line 182 will be subsequently opened. As noted above, the air pressure in the air inlet line 182 will remain at the set pressure level. The valves 196, 198 located in the split lines 192, 194 will then be individually opened to expose the "test area" to the set pressure. Once the pressure in the respective test zones tends to stabilize, the valves 196, 198 are closed to isolate the respective test zones from the air inlet pipe _ line 182. The differential pressure sensors 202, 204 will compare the pressure in the test zone to the set pressure in the air inlet line 182. If there is no leak in the test pressure zone, the first and second differential pressure sensors 202, 204 should not A pressure difference is sensed 'There is no pressure change indicating that the transitioner housing 1 1 2, 132 or the test area associated therewith is not leaking. The valves 214, 218 in the leak lines 212, 216 will then open to allow the "set pressure" to leak or release from the respective test pressure zones. The first and second differential pressure sensors 202, 204 will sense a change in pressure differential between the respective test pressure zones and the set pressure within the air inlet line 182, the pressure change indicating that the leaks 212, 24 200808387 216 are not Blocking, while there is no pressure difference change between the test zone and the set pressure in the air inlet line 182, indicates that the leak in the test zone has become blocked. After the aforementioned test to determine whether the test area is sound and the leak is functioning properly, the water filter soundness test is followed. According to an embodiment of the invention 'this transitional soundness test comprises two phases, in which case valves 54, 154 and 164 are both closed to isolate first and second filter assemblies Π〇, 130 from fluid circulation system 40 And isolated from each other. The valves 152, 162 are in the open position, while the valves 124, 144, 234, 238 in the discharge lines 122, 142, 232, 236 are closed and the valves 214, 218 in the leak lines 212, 216 are also closed. The crucible 184 in the air inlet 182 is then opened to allow pressurized gas to enter the branch lines 192, 194, as described above, and the air pressure in the air inlet line 182 maintains the level of the set pressure. Valves 196, 198 in supply lines 192, 194 are then opened to allow pressurized gas to enter each of the test zones associated with each filter assembly 110, 130. After the preset time has elapsed, the pressure in each of the test zones will stabilize at the above set pressure level, at which point valves 196, 198 will be closed. As the pressure in the respective test zones stabilizes at the "set pressure", the valves 234, 238 and the valves 214, 218 in the leak lines 212, 216, which are separate from the discharge lines 232, 236, will be opened. It will be appreciated that there will be a pressure differential across the fluid restrictors 215, 219 across the filter elements 114, 134 and through the leak lines 212, 216. In other words, since the valves 234, 238 connect the inner chambers 118, 138 to the discharge ports, the pressure present in the inner chambers 118, 138 of the filter assemblies 110, 130 will be less, and similarly, due to the 25 200808387 leak line connector The atmosphere will therefore build a lower pressure outside of the fluid limiters 215, 219. The high pressure in the outer chambers 116, 136 will slowly escape through the filter elements 114, 134 and through the fluid restrictors 215, 219 of the leak lines 212, 216, and the differential pressure sensors 202, 204 sense the inner chamber 118, 138 and the pressure difference between the set pressure levels in line 182. The system controller monitors the pressure difference over time and determines the pressure drop per unit time in each individual test area, Qsys, which is the unit that passes through the filter elements n4, 134 and the leak line 112, Π 6 Time pressure drop value. Measuring the rate of change of pressure across the filter elements 114, 134 and through the leak lines 212, 216 is the first of the two-stage filter tests. After completion of the first stage, the valves 214, 218 in the leak lines 212, 216 and the valves 234, 238 in the discharge lines 232, 236 are closed. The valves 196, 198 are then opened, and the set pressure levels are again constructed for the filter set 11 〇, 13 个别 in the individual test zones, and then the valves 196, 198 are closed. The valves 234, 238 in the discharge lines 232, 236 are opened, and the valves 214, 218 in the leak line lines 212, 216 remain closed. When pressure is dissipated through the filter elements 114, 134, the system controller will monitor the differential pressure transducers 202, 204 for changes in pressure differential sensed over a period of time. In this case, the second phase of the filter validation procedure repeats the first phase, but closes the leak. The system controller monitors the change in pressure differential over a period of time and determines the pressure drop per unit time for each individual test area. Qfilter' This is the pressure drop per unit time caused by the pressure dissipation through only the filter element. 26 200808387 With the information obtained above, the system controller will determine if the pressure change indicates that the flow through the filter elements 114, 134 is appropriate, in which case the system controller determines the difference between Qsys and Q ribs. , the pressure T drop value per unit time of the leak hole QQdf. The system controller then determines the unit pressure value cal for each volume by dividing Q^if by Qcal, which is the calibrated V〇lumetric flow theory for the expected test, ie, the set pressure. This CAL value is the relationship between the volumetric flow rate of the leak _ and the corresponding pressure drop caused by the system for each volume of pressure. The fluid diffusivity is then determined by dividing Qswf by CAL to calculate the individual water filter elements, which is calculated as the fluid diffusivity based on the filter pressure drop and the calculation of the leaky filter. An abnormal pressure change indicates the presence of helium in the filter elements 114, 134, which in turn represents the need to replace the filter assembly u or the filter assembly 130, and the device 1 is not disinfected or microbiologically deactivated. In this case, the filter element 114 or the filter element 134 indicates that the water has not been filtered to the desired level and the contaminated water may have entered the inner chamber 36. However, even though one of the two filter elements 114, 134 is believed to be sufficient to provide sufficient filtration to ensure microbiological deactivation or disinfection of the water, the device 10 preferably indicates operation when it detects that only one filter element is defective. There are flaws. Although the above-mentioned § 戌 测试 测试 test, leak hole soundness test and filter soundness test are performed simultaneously, these tests for individual filter components Π0, 130 and associated test areas can also be performed independently. The present invention thus provides a water filtration system for use in a poison or microbial deactivation reprocessor that reduces microbial contaminants and the like from entering the inner chamber 36 with water. Referring to the third drawing, there is shown a water filtration system 1 of another embodiment of the present invention. Basically, the bypass system 30 shown in the third figure allows the second filter assembly i3 to be bypassed during the processing phase. In this case, the microbial deactivation fluid is believed to be able to degrade certain filter elements' to make their water purification performance worse. For example, the surfactant in the microbial deactivating fluid _ can cause the filter to clog, especially when the pore size of the filter is extremely small. Accordingly, it is desirable to be able to limit the chance of exposure of the second filter element 〖3() to the deactivated fluid. In the embodiment shown, one end of the split line 3〇2 is connected to the second section 62b of the fluid supply line 62 and the other end is connected to the third section 62c of the fluid supply line 62. The valve 304 controls the flow through the flow line 302 and the valve 304 is normally closed to block fluid from passing through the split line 302 as it flows through the second filter assembly 130. The second filter assembly 130 can be bypassed by closing the valves 162, 164 and opening the valve 304 in the split line 302, thereby allowing fluid to flow through the fluid supply line to bypass the second filter assembly 130. . The embodiment of the third figure operates under the control of the system controller to prevent the flow of deactivated fluid through the second transition assembly 130 during the microbial deactivation of the active fluid generation and circulation stages. During the water entry or wash phase, the controller will control the individual valves 304, 162, 164 to allow the incoming water to flow through the second filter assembly while providing disinfected or microbial deactivated at each water injection or wash stage. Water. Please refer to the fourth figure, which presents another embodiment of water filtration, system 1 ,, and which has a single filter assembly 410. The filter assembly 41A includes a housing 412 and two outer filter elements 414, 416. Both transition elements 414 and 416 are bacterial retention size exclusion filters, preferably will typically be zero. Mycobacteria of 12 microns or larger is filtered out. The filter element 414, am may comprise a cylindrical support layer (not shown), such as a polyvinylidene fluoride or polyether ruthenium film. The filter membrane may be in the form of a capillary or hollow fiber membrane (or fiber) or may be a flat sheath of a membrane formed on the inner or outer surface of a flat macroporous support, or a sheet or film, or a film on a porous support. . The annular outer chamber 422 is defined between the outer filter element 414 and the outer casing 412, the intermediate chamber 424 is defined between the outer filter element 414 and the inner filter, element 416, and the inner chamber 426 is defined by the filter element 416. . As shown in the fourth figure, the filter assembly 41 is disposed in the system supply line 62, the discharge line 142 is in communication with the outer chamber 422, and the discharge line 235 is in communication with the inner chamber 426. As indicated in the head of the fourth figure, the fluid flowing through the system supply line 162 first passes through the outer filter element 414 and then through the inner chamber 416. In this case, the internal filter 416 is the downstream line of the outer filter element 414. Accordingly, the filter assembly 4H) provides the same effect as the embodiment shown in the second figure, however, the single-filter assembly 41 reduces the number of ports of the water filtration system and the number of connections, thereby increasing its reliability and efficacy. In addition to simplifying the overall structure, reducing the number of passers g and reducing the number of connecting lines, the overall volume of the circulating system 4G is also reduced, which also reduces the number of liquidized sub-actions required in the system. It is also understood that the aforementioned leak test, leak hole soundness test and filter health test can also be performed on the filter unit 41〇 and 29 200808387 related "test area". The above is a specific embodiment of the present invention, and it should be understood that the embodiments are only for the purpose of the invention, and those having ordinary knowledge in the field of the invention should be able to carry out various kinds without departing from the spirit and scope of the invention. Transform and adjust. According to another embodiment of the invention, the heater 1〇2 in the third section 62c of the fluid supply line 62 is used to add 10 to the water flowing through the section 6 to a level sufficient to pass the first The temperature of the disease in the water of the second filter element 11 〇, 130 = deactivation. As described above, preferably, the virus suppression device 52 of the ultraviolet treatment device will process the incoming water to deactivate the friend body therein, and the heater 102 acts as the second virus suppression device to interact with the virus suppression device 52, or Even replaced it. In this case, the heater also treats the incoming water to deactivate the organism therein. In the second example of the present invention, the water flowing through the third section 62c of the fluid supply line W is heated by the heater 1〇2 to about 105 degrees Celsius to 105 degrees Celsius. In another embodiment of the invention, the water flowing through the third section 62c of the fluid supply line 62 is heated to between about 55 degrees Celsius and 85 degrees Celsius. In a preferred embodiment of the invention, the water is preferably heated to between about 75 degrees Celsius and 85 degrees Celsius.圭#,,, σσ 1 are used as the disease=suppression device only in the cleaning stage of the disinfection cycle. In this case, the water entering the circulation system and the inner chamber 36 during the water injection phase is due to When the chemical system is generated and exposed during the operation of the circulation system, the disinfecting chemicals are introduced into the water from the chemical delivery and distribution container 72, and are microbially sterilized or sterilized. Accordingly, any viral perspiration present in the water in equipment 〇 200808387 will be deactivated by chemicals. Since no deactivated chemical or (4) agent is introduced into the washing water L, the heater 102 is used in the washing stage, and when the water enters the inner chamber 36, it is filtered through the first and second furnace components 11〇, 13〇. Afterwards, any bacteria that may be present in the water are deactivated. Therefore, it is necessary to further ensure the sterilization state of the instruments and equipment in the interior 36. Preferably, the heater 102 is used to deactivate the bacteria 10 during the cleaning phase of the sterilization cycle. It should be understood that the heater 102 can also be used to heat the inner chamber by the chemical during the chemical production and exposure stages. In this case, τ, by heating the chemical during the chemical generation and exposure phases of the operation cycle, enhances the sterilization characteristics of the chemical introduced into the container 72. The heater 102 can also be used to heat this through the fluid circulation system 4 as the fluid circulates through the fluid circulation system 40 during the deactivation phase. This case shall contain all adjustments and changes that do not deviate from the scope of the request and the scope of the case. [Simple description of the diagram] The first figure is a schematic diagram of the microbial deactivation system. The second figure is a schematic diagram of a filtration system depicting one embodiment of the present invention. The second drawing is a partial view of the filtering system presented in the second drawing, which shows another embodiment. ^ 弟四图 is a schematic diagram of a filter, a system, which presents another embodiment of the present invention. 31 200808387 [Description of main component symbols] 42 water inlet line 54 water valve 62 system feeder line 62a first section 62b second section 62c third section 88 system System return line 92 pump 100 filtration system 102 heater 110 first filter assembly 112 housing 114 filter element 116 annular outer chamber 118 Inner chamber 122 drain line 124 valve 130 second filter assembly 132 housing 134 filter element 136 annular outer chamber 138 inner chamber 142 drain line 144 valve 152 valve 154 valve 162 valve 164 valve 172 shunt line (bypass line) 174 direction confirmation valve ( Directional check valve 180 filter purge manifold system 182 intake line 184 control valve 188 vent line 32 200808387 189 control valve 192 split return line 194 split return line 196 control valve 198 Control valve 202 first pressure sensor 204 second pressure sensor 212 first leak line line 214 valve 215 flow limit 216 leak valve 219 in line 218 to adjust the flow restrictor valve 222 (regulating valve) 232 exhaust valve 236 line 234 line 238 exhaust valve 33