TW200740828A - New physical form of N,N'-disubstituted oxabispidines - Google Patents

New physical form of N,N'-disubstituted oxabispidines

Info

Publication number
TW200740828A
TW200740828A TW095121000A TW95121000A TW200740828A TW 200740828 A TW200740828 A TW 200740828A TW 095121000 A TW095121000 A TW 095121000A TW 95121000 A TW95121000 A TW 95121000A TW 200740828 A TW200740828 A TW 200740828A
Authority
TW
Taiwan
Prior art keywords
oxabispidines
disubstituted
physical form
new physical
crystalline material
Prior art date
Application number
TW095121000A
Other languages
Chinese (zh)
Inventor
Anne Juppo
Gerald Steele
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TW200740828A publication Critical patent/TW200740828A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)

Abstract

There is provided a crystalline material consisting essentially of a compound of formula I, wherein R1 to R4, A, B and D have meanings given in the description, which crystalline material is characterised in that is has surface area of less than 0.7 m<SP>2</SP>g<SP>-1</SP>. There are also provided processes for preparing such crystalline materials.
TW095121000A 2005-06-20 2006-06-13 New physical form of N,N'-disubstituted oxabispidines TW200740828A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0501428 2005-06-20

Publications (1)

Publication Number Publication Date
TW200740828A true TW200740828A (en) 2007-11-01

Family

ID=37570714

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095121000A TW200740828A (en) 2005-06-20 2006-06-13 New physical form of N,N'-disubstituted oxabispidines

Country Status (3)

Country Link
AR (1) AR053901A1 (en)
TW (1) TW200740828A (en)
WO (1) WO2006137772A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3319968A1 (en) 2015-07-06 2018-05-16 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
JP6936796B2 (en) 2015-07-06 2021-09-22 ロダン・セラピューティクス，インコーポレーテッド Histone deacetylase heterohalo inhibitor
EP3570834B1 (en) 2017-01-11 2021-12-22 Alkermes, Inc. Bicyclic inhibitors of histone deacetylase
JP7152471B2 (en) 2017-08-07 2022-10-12 ロダン・セラピューティクス，インコーポレーテッド Bicyclic inhibitor of histone deacetylase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (en) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030756A1 (en) * 2000-10-02 2003-09-03 Astrazeneca Ab COMPOUND OF OXABISPIDINE USEFUL IN THE TREATMENT OF CARDIAC ARRITMIES
SE0101324D0 (en) * 2001-04-12 2001-04-12 Astrazeneca Ab New process
SE0101327D0 (en) * 2001-04-12 2001-04-12 Astrazeneca Ab New crystalline forms
SE0201374D0 (en) * 2002-05-06 2002-05-06 Astrazeneca Ab Pharmaceutical combination
SE0201662D0 (en) * 2002-05-31 2002-05-31 Astrazeneca Ab Pharmaceutical combination
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate

Also Published As

Publication number Publication date
WO2006137772A1 (en) 2006-12-28
AR053901A1 (en) 2007-05-23

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