TW200732477A - Crystal structure of soluble glutaminyl cyclase - Google Patents

Crystal structure of soluble glutaminyl cyclase

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Publication number
TW200732477A
TW200732477A TW095106425A TW95106425A TW200732477A TW 200732477 A TW200732477 A TW 200732477A TW 095106425 A TW095106425 A TW 095106425A TW 95106425 A TW95106425 A TW 95106425A TW 200732477 A TW200732477 A TW 200732477A
Authority
TW
Taiwan
Prior art keywords
glutaminyl cyclase
crystal structure
soluble
methods
relates
Prior art date
Application number
TW095106425A
Other languages
Chinese (zh)
Other versions
TWI310052B (en
Inventor
Andrew Huei-Jiun Wang
Kai-Fa Huang
Original Assignee
Academia Sinica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academia Sinica filed Critical Academia Sinica
Priority to TW95106425A priority Critical patent/TWI310052B/en
Publication of TW200732477A publication Critical patent/TW200732477A/en
Application granted granted Critical
Publication of TWI310052B publication Critical patent/TWI310052B/en

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention relates to a crystalline structure of glutaminyl cyclase (QC). The invention also relates to the methods of preparing the crystalline structure of QC and the methods for identifying candidate inhibitors of QC. This invention further provides a structural basis for the rational design or identification of new inhibitors that may be used to treat QC-associated disorders.
TW95106425A 2006-02-24 2006-02-24 Crystal structure qc 6.5 of soluble glutaminyl cyclase TWI310052B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW95106425A TWI310052B (en) 2006-02-24 2006-02-24 Crystal structure qc 6.5 of soluble glutaminyl cyclase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW95106425A TWI310052B (en) 2006-02-24 2006-02-24 Crystal structure qc 6.5 of soluble glutaminyl cyclase

Publications (2)

Publication Number Publication Date
TW200732477A true TW200732477A (en) 2007-09-01
TWI310052B TWI310052B (en) 2009-05-21

Family

ID=45072158

Family Applications (1)

Application Number Title Priority Date Filing Date
TW95106425A TWI310052B (en) 2006-02-24 2006-02-24 Crystal structure qc 6.5 of soluble glutaminyl cyclase

Country Status (1)

Country Link
TW (1) TWI310052B (en)

Also Published As

Publication number Publication date
TWI310052B (en) 2009-05-21

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