TW200730171A - Compositions and methods of administering rapamycin analogs with paclitaxel using medical devices - Google Patents
Compositions and methods of administering rapamycin analogs with paclitaxel using medical devicesInfo
- Publication number
- TW200730171A TW200730171A TW095137943A TW95137943A TW200730171A TW 200730171 A TW200730171 A TW 200730171A TW 095137943 A TW095137943 A TW 095137943A TW 95137943 A TW95137943 A TW 95137943A TW 200730171 A TW200730171 A TW 200730171A
- Authority
- TW
- Taiwan
- Prior art keywords
- agents
- drugs
- compositions
- medical devices
- paclitaxel
- Prior art date
Links
Abstract
Systems and compositions comprising paclitaxel and a second drug, such as rapamycin, analogs, derivatives, salts and esters thereof are disclosed, as well as methods of delivery wherein the drugs have effects that complement each other. Medical devices comprising supporting structures capable of including or supporting a pharmaceurically acceptable carrier or excipient, which carrier or excipient can contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating including the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. These compositions and systems can be used in combination with other drugs, including anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these and other drugs.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72708005P | 2005-10-14 | 2005-10-14 | |
US72719605P | 2005-10-14 | 2005-10-14 | |
US72687805P | 2005-10-14 | 2005-10-14 | |
US73257705P | 2005-10-17 | 2005-10-17 | |
US11/548,974 US8057816B2 (en) | 1997-09-26 | 2006-10-12 | Compositions and methods of administering paclitaxel with other drugs using medical devices |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200730171A true TW200730171A (en) | 2007-08-16 |
TWI484952B TWI484952B (en) | 2015-05-21 |
Family
ID=53723493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095137943A TWI484952B (en) | 2005-10-14 | 2006-10-14 | Compositions and methods of administering rapamycin analogs with paclitaxel using medical devices |
Country Status (1)
Country | Link |
---|---|
TW (1) | TWI484952B (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005537854A (en) * | 2002-09-06 | 2005-12-15 | アボット・ラボラトリーズ | Medical device comprising a hydration inhibitor |
ITTO20040056A1 (en) * | 2004-02-05 | 2004-05-05 | Sorin Biomedica Cardio Spa | STENT FOR THE ENDOLIMINAL DELIVERY OF PRINCIPLES OR ACTIVE AGENTS |
-
2006
- 2006-10-14 TW TW095137943A patent/TWI484952B/en active
Also Published As
Publication number | Publication date |
---|---|
TWI484952B (en) | 2015-05-21 |
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