TW200722409A - Preparation of thioalkylamines using chlorosulfonic acid - Google Patents

Preparation of thioalkylamines using chlorosulfonic acid

Info

Publication number
TW200722409A
TW200722409A TW095130898A TW95130898A TW200722409A TW 200722409 A TW200722409 A TW 200722409A TW 095130898 A TW095130898 A TW 095130898A TW 95130898 A TW95130898 A TW 95130898A TW 200722409 A TW200722409 A TW 200722409A
Authority
TW
Taiwan
Prior art keywords
preparation
formula
chlorosulfonic acid
thioalkylamines
reacting
Prior art date
Application number
TW095130898A
Other languages
Chinese (zh)
Inventor
Harry Blaschke
Sergiy Pazenok
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of TW200722409A publication Critical patent/TW200722409A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/24—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfuric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a novel process for the preparation of compounds of the formula (I), by reacting in a first step amino alcohols of the formula (II), with chlorosulfonic acid to give sulfuric acid esters of the general formula (III), and by reacting these sulfuric acid esters in a second step with mercaptans or salts thereof the general formula (IV) RSM (IV) in each formula, where applicable, R1, R2, R3, R4, R5, R6, R, n and M have the meanings given in the description, in the presence of a diluent and in the presence of a base.
TW095130898A 2005-08-24 2006-08-23 Preparation of thioalkylamines using chlorosulfonic acid TW200722409A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05018348 2005-08-24

Publications (1)

Publication Number Publication Date
TW200722409A true TW200722409A (en) 2007-06-16

Family

ID=37101913

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095130898A TW200722409A (en) 2005-08-24 2006-08-23 Preparation of thioalkylamines using chlorosulfonic acid

Country Status (7)

Country Link
EP (1) EP1981841A1 (en)
KR (1) KR20080036634A (en)
BR (1) BRPI0615132A2 (en)
IL (1) IL189465A0 (en)
MX (1) MX2008002437A (en)
TW (1) TW200722409A (en)
WO (1) WO2007022901A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201329025A (en) 2011-11-01 2013-07-16 Astex Therapeutics Ltd Pharmaceutical compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1216988A4 (en) * 1999-09-28 2005-04-20 Nihon Nohyaku Co Ltd Thioalkylamine derivatives and process for the preparation thereof
KR100994169B1 (en) * 2002-05-24 2010-11-15 바이엘 크롭사이언스 아게 Process for the preparation of thioalkylamine derivatives

Also Published As

Publication number Publication date
IL189465A0 (en) 2008-08-07
EP1981841A1 (en) 2008-10-22
WO2007022901A1 (en) 2007-03-01
KR20080036634A (en) 2008-04-28
BRPI0615132A2 (en) 2011-05-03
MX2008002437A (en) 2008-04-03

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