TW200718699A - Fused bicycloheterocycle substituted quinuclidine derivatives - Google Patents

Fused bicycloheterocycle substituted quinuclidine derivatives

Info

Publication number
TW200718699A
TW200718699A TW095121229A TW95121229A TW200718699A TW 200718699 A TW200718699 A TW 200718699A TW 095121229 A TW095121229 A TW 095121229A TW 95121229 A TW95121229 A TW 95121229A TW 200718699 A TW200718699 A TW 200718699A
Authority
TW
Taiwan
Prior art keywords
compounds
quinuclidine derivatives
fused bicycloheterocycle
substituted quinuclidine
bicycloheterocycle substituted
Prior art date
Application number
TW095121229A
Other languages
Chinese (zh)
Inventor
Jian-Guo Ji
Tao Li
Kathleen H Mortell
Michael R Schrimpf
Diana L Nersesian
Liping Pan
William H Bunnelle
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/744,208 external-priority patent/US7160876B2/en
Priority claimed from US11/015,236 external-priority patent/US20050137204A1/en
Priority claimed from US11/153,762 external-priority patent/US20050245531A1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of TW200718699A publication Critical patent/TW200718699A/en

Links

Abstract

Compounds of formula (I), wherein n is 0, 1, or 2; A is N or N+-O-; X is O, S, -NH-, and -N-alkyl-; Ar1 is a 6- membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
TW095121229A 2003-12-22 2006-06-14 Fused bicycloheterocycle substituted quinuclidine derivatives TW200718699A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/744,208 US7160876B2 (en) 2003-12-22 2003-12-22 Fused bicycloheterocycle substituted quinuclidine derivatives
US11/015,236 US20050137204A1 (en) 2003-12-22 2004-12-17 Fused bicycloheterocycle substituted quinuclidine derivatives
US11/153,762 US20050245531A1 (en) 2003-12-22 2005-06-15 Fused bicycloheterocycle substituted quinuclidine derivatives

Publications (1)

Publication Number Publication Date
TW200718699A true TW200718699A (en) 2007-05-16

Family

ID=57911861

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095121229A TW200718699A (en) 2003-12-22 2006-06-14 Fused bicycloheterocycle substituted quinuclidine derivatives

Country Status (1)

Country Link
TW (1) TW200718699A (en)

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