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Publication of TW200716625ApublicationCriticalpatent/TW200716625A/en
C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
C07B2200/00—Indexing scheme relating to specific properties of organic compounds
C07B2200/07—Optical isomers
Abstract
This invention relates to novel enantiomers useful as monoamine neuro-transmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.