TW200643029A - Pegylated interferon alpha-1B - Google Patents

Pegylated interferon alpha-1B

Info

Publication number
TW200643029A
TW200643029A TW094128279A TW94128279A TW200643029A TW 200643029 A TW200643029 A TW 200643029A TW 094128279 A TW094128279 A TW 094128279A TW 94128279 A TW94128279 A TW 94128279A TW 200643029 A TW200643029 A TW 200643029A
Authority
TW
Taiwan
Prior art keywords
interferon alpha
pegylated interferon
conjugates
peg
peg moiety
Prior art date
Application number
TW094128279A
Other languages
Chinese (zh)
Inventor
Chun Shen
Ying Buechler
xiao-chun Chen
Dawn X Wen
Yi-Xin Wang
Shehui He
Qianlan Wang
Original Assignee
Egen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egen Corp filed Critical Egen Corp
Publication of TW200643029A publication Critical patent/TW200643029A/en

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides PEG-IFN α-1b conjugates, where a PEG moiety is covalently bound to Cys86 of human IFNα-1b conjugates. A pharmaceutical composition and a method for treating inflammatory diseases, infections, and cancer are also provided. The invention further relates to a method for the modification of interferons by conjugation of a PEG moiety to free cysteine residues in interferon molecules.
TW094128279A 2005-06-09 2005-08-19 Pegylated interferon alpha-1B TW200643029A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68915505P 2005-06-09 2005-06-09

Publications (1)

Publication Number Publication Date
TW200643029A true TW200643029A (en) 2006-12-16

Family

ID=57810089

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094128279A TW200643029A (en) 2005-06-09 2005-08-19 Pegylated interferon alpha-1B

Country Status (1)

Country Link
TW (1) TW200643029A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI555758B (en) * 2011-06-14 2016-11-01 江蘇恆瑞醫藥股份有限公司 An interferon conjugate modified by peg

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI555758B (en) * 2011-06-14 2016-11-01 江蘇恆瑞醫藥股份有限公司 An interferon conjugate modified by peg

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