TW200639183A - Immune enhancer - Google Patents

Immune enhancer

Info

Publication number
TW200639183A
TW200639183A TW095103096A TW95103096A TW200639183A TW 200639183 A TW200639183 A TW 200639183A TW 095103096 A TW095103096 A TW 095103096A TW 95103096 A TW95103096 A TW 95103096A TW 200639183 A TW200639183 A TW 200639183A
Authority
TW
Taiwan
Prior art keywords
moiety
immune enhancer
molecular weight
weight polysaccharide
rabinose
Prior art date
Application number
TW095103096A
Other languages
Chinese (zh)
Inventor
Hiroaki Maeda
Yasuo Ninomiya
Original Assignee
Daiwa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiwa Pharmaceutical Co Ltd filed Critical Daiwa Pharmaceutical Co Ltd
Publication of TW200639183A publication Critical patent/TW200639183A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A high-molecular weight polysaccharide containing an arabinogalactan moiety comprising D-galactose, an arabinoxylan moiety comprising D-xylose, an arabinan moiety comprising L-rabinose and a glucan moiety comprising D-glucose. An immune enhancer comprising this high-molecular weight polysaccharide more clearly participates in immunopotentiation by, for example, activating macrophages.
TW095103096A 2005-02-04 2006-01-26 Immune enhancer TW200639183A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2005/001684 WO2006082647A1 (en) 2005-02-04 2005-02-04 Immunopotentiator

Publications (1)

Publication Number Publication Date
TW200639183A true TW200639183A (en) 2006-11-16

Family

ID=36777042

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095103096A TW200639183A (en) 2005-02-04 2006-01-26 Immune enhancer

Country Status (2)

Country Link
TW (1) TW200639183A (en)
WO (2) WO2006082647A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108530547A (en) * 2018-02-26 2018-09-14 华南农业大学 A kind of arabogalactan KMCP and preparation method thereof and the application in preparing immunomodulator

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106519053A (en) * 2016-11-04 2017-03-22 西华师范大学 Novel natural product amanita caesarea polysaccharide AC-1 and application thereof
CN108567793B (en) * 2018-02-12 2020-06-26 南京农业大学 Application of ganoderma lucidum polysaccharide in preparation of traditional Chinese medicine immunopotentiator

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5941302A (en) * 1982-09-01 1984-03-07 Noda Shiyokukin Kogyo Kk Preparation of polysaccharide
JPS6466203A (en) * 1987-09-07 1989-03-13 Hiroshi Hikino Polysaccharide, isolation and use thereof
JP2532899B2 (en) * 1987-12-10 1996-09-11 憲一 小砂 Method for producing bioactive hemicellulose
JPH0611764B2 (en) * 1988-12-07 1994-02-16 雪印乳業株式会社 Method for producing water-soluble hemicellulose
JP2787252B2 (en) * 1991-06-17 1998-08-13 雪印乳業株式会社 Colorectal cancer inhibitor
GB2261671B (en) * 1991-11-16 1996-07-03 Gb Biotech Gel production from plant matter
JPH07113001A (en) * 1993-08-23 1995-05-02 Tsumura & Co Novel polysaccharide and radiation-preventing agent containing the polysaccharide as active ingredient
US5560914A (en) * 1995-07-12 1996-10-01 Daiwa Pharmaceutical Co., Ltd. Immunopotentiator and method of manufacturing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108530547A (en) * 2018-02-26 2018-09-14 华南农业大学 A kind of arabogalactan KMCP and preparation method thereof and the application in preparing immunomodulator
CN108530547B (en) * 2018-02-26 2021-01-19 华南农业大学 Arabinogalactan KMCP, its preparation method and application in preparing immunomodulator

Also Published As

Publication number Publication date
WO2006082707A1 (en) 2006-08-10
WO2006082647A1 (en) 2006-08-10

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