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Application filed by Powderject Vaccines IncfiledCriticalPowderject Vaccines Inc
Publication of TW200628611ApublicationCriticalpatent/TW200628611A/en
Micro-Organisms Or Cultivation Processes Thereof
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Abstract
A nucleic acid construct comprising a chimeric promoter sequence and a cloning site for insertion of a coding sequence in operable linkage with the chimeric promoter, wherein the chimeric promoter sequence comprises: (a) a Hcmv immediate early promoter sequence; (b) exon 1 and at least a part of exon 2 of the hCMV major immediate early gene; and c a heterologous intron provided in place of the intron A region of the hCMV major immediate early gene.