TW200619224A - Flavone derivatives as TNF- α inhibitors or antagonists - Google Patents

Flavone derivatives as TNF- α inhibitors or antagonists

Info

Publication number
TW200619224A
TW200619224A TW093137635A TW93137635A TW200619224A TW 200619224 A TW200619224 A TW 200619224A TW 093137635 A TW093137635 A TW 093137635A TW 93137635 A TW93137635 A TW 93137635A TW 200619224 A TW200619224 A TW 200619224A
Authority
TW
Taiwan
Prior art keywords
tnf
antagonists
inhibitors
flavone derivatives
hydroxy
Prior art date
Application number
TW093137635A
Other languages
Chinese (zh)
Other versions
TWI376384B (en
Inventor
li-wei Xu
Su-Zhen Zhang
Kuo-Sheng Chuang
Chen-Shiang Shen
Yuan-Xiu Liao
Original Assignee
Advanced Gene Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Gene Technology Corp filed Critical Advanced Gene Technology Corp
Priority to TW093137635A priority Critical patent/TW200619224A/en
Publication of TW200619224A publication Critical patent/TW200619224A/en
Application granted granted Critical
Publication of TWI376384B publication Critical patent/TWI376384B/zh

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The use of flavone derivatives of formula (I), in which R1, R2, R3, R4 and R5 independently represent hydrogen, hydroxy or an ester group; R6 represents hydrogen, hydroxy, an ester group or an O-glycoside group such as O-rhamnose, O-glucoside, O-retinoside or O-xyloside; and - - - represents a single bond or a double bond; or the pharmaceutically acceptable salts thereof as TNF α antagonists or inhibitors.
TW093137635A 2004-12-06 2004-12-06 Flavone derivatives as TNF- α inhibitors or antagonists TW200619224A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW093137635A TW200619224A (en) 2004-12-06 2004-12-06 Flavone derivatives as TNF- α inhibitors or antagonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW093137635A TW200619224A (en) 2004-12-06 2004-12-06 Flavone derivatives as TNF- α inhibitors or antagonists

Publications (2)

Publication Number Publication Date
TW200619224A true TW200619224A (en) 2006-06-16
TWI376384B TWI376384B (en) 2012-11-11

Family

ID=48087805

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093137635A TW200619224A (en) 2004-12-06 2004-12-06 Flavone derivatives as TNF- α inhibitors or antagonists

Country Status (1)

Country Link
TW (1) TW200619224A (en)

Also Published As

Publication number Publication date
TWI376384B (en) 2012-11-11

Similar Documents

Publication Publication Date Title
UA94065C2 (en) Dihydropseudoerythromycin derivatives
MX2007003546A (en) Indozolone derivatives as 11b-hsd1 inhibitors.
SG151254A1 (en) Substituted morpholine and thiomorpholine derivatives
RS20050462A (en) Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
NO20073551L (en) Nikotinacetylkolinreseptorligander
TW200635897A (en) Piperidine derivatives and their use as anti-inflammatory agents
SE0202463D0 (en) Novel compounds
NO20044866L (en) Pyrazolo-pyrimidine-aniline compounds useful as kinase inhibitors
SG164288A1 (en) Chemokine receptor antagonists
MX2009014208A (en) Heterocyclic compounds and use thereof as erk inhibitors.
GEP20094666B (en) Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
GEP20094638B (en) Benzimidazolone carboxylic acid derivatives
TW200716628A (en) Novel compounds
NO20052182L (en) New connections
GB0314967D0 (en) Piperazine derivatives
AU2001230395A1 (en) Use of cox-2 inhibitors as gastroprokinetics
AU2003250471A1 (en) Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors
TW200508199A (en) Novel compound
MXPA02012054A (en) Tetracyclic diketopiperazine compounds as pdev inhibitors.
RS20060280A (en) Novel keto-oxadiazole derivatives as cathepsin inhibitors
SG162766A1 (en) Benzooxazole-2-on derivatives as lipase and phospholipase inhibitors
NO20080133L (en) Azolopyridin-2-one derivatives such as lipase and phospholipase inhibitors
GEP20094801B (en) Tetrazole derivatives and methods of treatment of metabolic-related disorders thereof
MY136938A (en) New process for the synthesis of perindopril and its pharmaceutically acceptable salts
MY138550A (en) Method for synthesis of perindopril and its pharmaceutically acceptable salts

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees