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Application filed by Japan Applied Microbiology Res Inst LtdfiledCriticalJapan Applied Microbiology Res Inst Ltd
Priority to TW093127239ApriorityCriticalpatent/TW200608894A/en
Publication of TW200608894ApublicationCriticalpatent/TW200608894A/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Medicines Containing Material From Animals Or Micro-Organisms
(AREA)
Abstract
This invention is to provide a nematocide which is extracted and purified form a culture liquid of a fungus belonging to the genus Aspergillus sp. The nematocide of this invention is characterized by containing, as the active ingredient, an organic acidic fraction extract which is obtained by adjusting, if needed, a culture supernatant of a fungus belonging to the genus Aspergillus sp. to pH 7 or lower, then fractionally extracting it with a first organic solvent separable from water, fractionally extracting the first organic solvent-extraction fraction thus obtained with an aqueous alkaline solution, adjusting the aqueous alkaline solution-extraction fraction thus obtained to pH 7, and then fractionally extracting it with a second organic solvent separable from water. This invented nematocide is also characterized by containing penicillic acid as the active ingredient.
A PROCESS FOR THE PREPARATION OF 17-HYDROXY-6 ß,7ß,15 ß,16 ß - BISMETHYLENE-17a-PREGN-4-ENE-3-ONE-21-CARBOXYLIC ACID Y-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS