TW200607809A - 4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists - Google Patents

4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

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Publication number
TW200607809A
TW200607809A TW093124549A TW93124549A TW200607809A TW 200607809 A TW200607809 A TW 200607809A TW 093124549 A TW093124549 A TW 093124549A TW 93124549 A TW93124549 A TW 93124549A TW 200607809 A TW200607809 A TW 200607809A
Authority
TW
Taiwan
Prior art keywords
nmda
cycloalkylaminopyrazolo
pyrimidine
nr2b antagonists
disease
Prior art date
Application number
TW093124549A
Other languages
Chinese (zh)
Inventor
Wayne Thompson
Steven D Young
Brian T Phillips
Peter Munson
Willie Whitter
Nigel Liverton
Christine Dieckhaus
John Butcher
John A Mccauley
Charles J Mcintyre
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to TW093124549A priority Critical patent/TW200607809A/en
Publication of TW200607809A publication Critical patent/TW200607809A/en

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Abstract

The present invention relates to compounds represented by formula (I): (where R1 and Y are defined herein) or pharmaceutically acceptable salts thereof, which are effective as NMDA/NR2B antagonists and are useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.
TW093124549A 2004-08-16 2004-08-16 4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists TW200607809A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW093124549A TW200607809A (en) 2004-08-16 2004-08-16 4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW093124549A TW200607809A (en) 2004-08-16 2004-08-16 4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

Publications (1)

Publication Number Publication Date
TW200607809A true TW200607809A (en) 2006-03-01

Family

ID=57807363

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093124549A TW200607809A (en) 2004-08-16 2004-08-16 4-cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

Country Status (1)

Country Link
TW (1) TW200607809A (en)

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