TW200517399A - A novel chimeric polypeptide and use thereof - Google Patents

A novel chimeric polypeptide and use thereof

Info

Publication number
TW200517399A
TW200517399A TW093125469A TW93125469A TW200517399A TW 200517399 A TW200517399 A TW 200517399A TW 093125469 A TW093125469 A TW 093125469A TW 93125469 A TW93125469 A TW 93125469A TW 200517399 A TW200517399 A TW 200517399A
Authority
TW
Taiwan
Prior art keywords
chimeric polypeptide
domain
nucleic acids
novel chimeric
polypeptide
Prior art date
Application number
TW093125469A
Other languages
Chinese (zh)
Inventor
Mizhou Hui
Original Assignee
Bioprotein Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprotein Llc filed Critical Bioprotein Llc
Publication of TW200517399A publication Critical patent/TW200517399A/en

Links

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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A chimeric polypeptide comprising a TNF neutralizer domain, an IL-1 receptor antagonist domain, and a dimerization domain, wherein the three domains are operably linked to each other. Within the scope of this invention are (i) nucleic acids encoding the polypeptide; (ii) expression vectors and host cells containing the nucleic acids; (iii) related pharmaceutical compositions; and (iv) related preparation and treatment methods.
TW093125469A 2003-08-26 2004-08-26 A novel chimeric polypeptide and use thereof TW200517399A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49798803P 2003-08-26 2003-08-26

Publications (1)

Publication Number Publication Date
TW200517399A true TW200517399A (en) 2005-06-01

Family

ID=39334847

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093125469A TW200517399A (en) 2003-08-26 2004-08-26 A novel chimeric polypeptide and use thereof

Country Status (2)

Country Link
CN (1) CN101166757A (en)
TW (1) TW200517399A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105200073B (en) * 2010-09-01 2019-03-01 山东新时代药业有限公司 Human tumor necrosis factor receptor-Fc fusion and its product albumen
CN107936124A (en) * 2017-12-31 2018-04-20 武汉班科生物技术股份有限公司 Fc fragment fusion proteins that TNFr strengthens with stability and resistance to aggregation and preparation method and application

Also Published As

Publication number Publication date
CN101166757A (en) 2008-04-23

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