TW200509941A - Pharmaceutical solution composition - Google Patents

Pharmaceutical solution composition

Info

Publication number
TW200509941A
TW200509941A TW093112302A TW93112302A TW200509941A TW 200509941 A TW200509941 A TW 200509941A TW 093112302 A TW093112302 A TW 093112302A TW 93112302 A TW93112302 A TW 93112302A TW 200509941 A TW200509941 A TW 200509941A
Authority
TW
Taiwan
Prior art keywords
solution composition
pharmaceutical solution
pharmaceutical
injection
present
Prior art date
Application number
TW093112302A
Other languages
Chinese (zh)
Inventor
Masaru Higaki
Takayuki Murakami
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of TW200509941A publication Critical patent/TW200509941A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

The present invention relates a pharmaceutical solution composition, which comprises (a) 4-amino-5-chloro-2-ethoxy-4-[[4-(4-fluorobe nzyl)-2-morpholinyl]methyl]benzamide(Comp und A),or a pharmaceutically acceptable salt thereof, (b) propyleneglycol, and (c) water. According to the present invention, a Compound A-containing pharmaceutical solution composition can be obtained, which is useful as a formulation for injection or an oral formulation, that is a pharmaceutical for injection or an oral formulation, that is , a pharmaceutical solution composition having a solubility and a pH value in a desired range as well as being highly stable can be obtained.
TW093112302A 2003-04-30 2004-04-30 Pharmaceutical solution composition TW200509941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003124694 2003-04-30

Publications (1)

Publication Number Publication Date
TW200509941A true TW200509941A (en) 2005-03-16

Family

ID=33410196

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093112302A TW200509941A (en) 2003-04-30 2004-04-30 Pharmaceutical solution composition

Country Status (6)

Country Link
JP (1) JP4607761B2 (en)
KR (1) KR101169478B1 (en)
CN (1) CN1812794B (en)
HK (1) HK1095737A1 (en)
TW (1) TW200509941A (en)
WO (1) WO2004096229A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080096779A (en) * 2006-01-20 2008-11-03 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Novel film-coated tablet
EP2117598A2 (en) * 2007-01-10 2009-11-18 Novartis AG Formulations of deacetylase inhibitors
KR101405615B1 (en) * 2007-08-27 2014-06-12 (주)아모레퍼시픽 Composition for external use containing stable benzamide compounds obtained by controlling pH of the composition, and method for stabilizing the benzamide compounds
NZ602392A (en) * 2010-03-18 2014-03-28 Innopharma Inc Stable bortezomib formulations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63264467A (en) * 1986-04-30 1988-11-01 Dainippon Pharmaceut Co Ltd Benzamide derivative
JP2002532535A (en) * 1998-12-22 2002-10-02 アメリカ合衆国 Water-insoluble drug delivery system

Also Published As

Publication number Publication date
KR20060004964A (en) 2006-01-16
KR101169478B1 (en) 2012-07-27
CN1812794A (en) 2006-08-02
WO2004096229A1 (en) 2004-11-11
CN1812794B (en) 2011-06-29
JPWO2004096229A1 (en) 2006-07-13
JP4607761B2 (en) 2011-01-05
HK1095737A1 (en) 2007-05-18

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