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Priority claimed from GB0304665Aexternal-prioritypatent/GB0304665D0/en
Priority claimed from GB0329446Aexternal-prioritypatent/GB0329446D0/en
Application filed by Teijin Pharma LtdfiledCriticalTeijin Pharma Ltd
Publication of TW200508236ApublicationCriticalpatent/TW200508236A/en
The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
5,7-diaminopyrazolo[4,3-d]pyrimidines with pde-5 inhibitory activity, compositions containing such derivatives and the use of such derivatives in the treatment of hypertension and other disorders