TW200504017A - Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors - Google Patents

Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Info

Publication number
TW200504017A
TW200504017A TW092130215A TW92130215A TW200504017A TW 200504017 A TW200504017 A TW 200504017A TW 092130215 A TW092130215 A TW 092130215A TW 92130215 A TW92130215 A TW 92130215A TW 200504017 A TW200504017 A TW 200504017A
Authority
TW
Taiwan
Prior art keywords
piperidine derivatives
uptake inhibitors
monoamine neurotransmitter
novel piperidine
novel
Prior art date
Application number
TW092130215A
Other languages
Chinese (zh)
Inventor
Frank Watjen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of TW200504017A publication Critical patent/TW200504017A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

This invention relates to novel piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
TW092130215A 2002-11-01 2003-10-30 Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors TW200504017A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201689 2002-11-01
DKPA200300727 2003-05-13

Publications (1)

Publication Number Publication Date
TW200504017A true TW200504017A (en) 2005-02-01

Family

ID=35295048

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092130215A TW200504017A (en) 2002-11-01 2003-10-30 Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Country Status (7)

Country Link
KR (1) KR20050071647A (en)
AR (1) AR041879A1 (en)
MY (1) MY135292A (en)
NO (1) NO20052624L (en)
NZ (1) NZ538514A (en)
RU (1) RU2325378C2 (en)
TW (1) TW200504017A (en)

Also Published As

Publication number Publication date
RU2325378C2 (en) 2008-05-27
KR20050071647A (en) 2005-07-07
RU2005107417A (en) 2006-01-20
AR041879A1 (en) 2005-06-01
NZ538514A (en) 2007-09-28
NO20052624L (en) 2005-05-31
MY135292A (en) 2008-03-31

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