200407167 B7 絰濟部智慧財產局員工消費合作社印製 五、發明説明（ [產業上之利用領域] S去;消^部的皺紋。皺紋是皮膚老化的 古ίϊΐίίΐ肌收縮時，皮膚會收縮而出現敏紋。正常年青的 文洁ί 當表情肌_後，皮膚會很快復原， 硬'、乾焊、茫力「皮膚開始明顯老化，皮膚變薄、變 目畜表丨肖肌鬆弛後，皮膚不能很快復原，久之 二ΐΐ齡的增大，皮膚和皮下組織更加鬆他，加上 作^3、；^的委縮或缺失，以及肌肉的鬆軟，皮膚會在重力的 作用下發生滑墜，形成更深的皺紋。 刀们 [習知的技術] 皱紋的誘發因素如下·· iff性 ①遺傳；②慢性消耗性疾病；③營養不良；④代 ϋτ η⑤内7刀泌功能異常；⑥神經精神不正常。以上諸因素可 2届度$皮ί ΐ養失調，气響皮膚的正常代謝功能及活動。 ①曰曬(紫外線能破壞真皮彈力纖維）、自由基或氧化 3生的⑥ςϊκ妝㈣.:④化學物如_ 活H貝。①面部表情過度的誇張，愁眉苦臉；②吸煙；③運動、 * J容J;方人體自身的平衡調 ii 藥的名稱、產地、劑量已與今大相 用嗖果ίίί不，^不，相關的研究也不夠深入，若盲目搬 用，效果不理想，逛可能對皮膚造成傷害。 -、中醫對皺紋的原因 ((:))ί??Ι: ΐί ?衰老時，皮膚老化，出現皺紋。 健，水〈靈框》指出··"若脾胃虛弱，運化失 ί衰氣血，則面部肌膚失去氣血之漂養而 本紙ί『尺度適用中) Α4· ( 210x1^7 ^1Τ'線 (請先閲讀背面之Vi-意事項存填寫本貢各攔) 200407167200407167 B7 Printed by the Consumers' Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 5. Description of the Invention ([Industrial Utilization Field] S Go; Eliminate the wrinkles of the Ministry. Wrinkles are skin aging when the muscles contract. The skin will shrink and appear Min Wen. Normal young Wenjie. When facial muscles appear, the skin will recover quickly, hard, dry, and weak. "The skin begins to age significantly, the skin becomes thinner, and the appearance of the animal's skin is reduced. It cannot be recovered quickly, and the skin and subcutaneous tissues become looser with the increase of age, and the contraction or loss of ^ 3, ^, and the softness of muscles, the skin will fall under the action of gravity. Deeper wrinkles are formed. Knives [known technique] The inducing factors of wrinkles are as follows: iff sex ① inheritance; ② chronic wasting disease; ③ malnutrition; ④ generation ϋτ η ⑤ inner 7 knife secretion abnormality; ⑥ neuropsychiatric Normal. The above factors can be used for 2 times. The skin is dystrophic, and the normal metabolic functions and activities of the skin are affected. ① Sun exposure (ultraviolet rays can destroy dermal elastic fibers), free radicals, or oxidation. ⑥ςϊκ 妆 ㈣. : ④ Chemicals such as _ live H shellfish. ① Exaggerated facial expressions, frowning face; ② Smoking; ③ exercise, * J Rong J; the body's own balance adjustment ii. The name, origin, and dosage of the drug have been used today.嗖 果 ίίί No, ^ No, the related research is not deep enough, if it is used blindly, the effect is not ideal, and shopping may cause damage to the skin.-, Causes of wrinkles by Chinese medicine ((:)) ί ??: 衰 ί? Aging As the skin ages, wrinkles appear. Health, water "Soul Box" points out that "If the spleen and stomach are weak and the blood is lost, the facial skin loses the vitality of qi and blood, and the paper is" the standard is applicable. "Α4 · (210x1 ^ 7 ^ 1Τ 'line (please read the Vi-Issue on the back and fill in each box in Bengon) 200407167
㈢足飲^ ，恤人的營養攝入ΐί;失;气=J。飲 二素52,成篇”多麵，則脈凝泣”，ΐί3乏Ϊ皮 經濟部智慧財產局員工消費合作社印製 (^f,fir；iirr^ (五)!J^f 3失疏泄致氣積f滞，血行不胃，脈絡雜於上， 曰使面部肌膚失血液之濡養而生皺紋。 上 ，紋是皮膚老化的結果，不可抗拒，但f卜些非自然 ί^ίίΐΐΙ’&蝴_&，職娜繼：其保健 不ϋϊΐ頭面而致之面色無華、蒼老多皱、髮白齒落、面 二ί二右"b使用益腎填精、補益氣血、調養脾胃、活血悅顏之品 組成的方劑，則可益容延年，抗老防皺。 、 以往之中華民國專利公告編號： 491710^：卩制角質細胞分化之含羥基脂肪酸醯胺與視網醇的醫藥組合 物視網醇經基脂肪酸醯胺。480178:含白藜蘆醇之化妝品组合物。 448161:環狀醯胺衍生物。445252:維生素D3類似物12卜二羥基纠6_ 烯-23-炔-20-表-膽鈣化固醇(choleca丨ciferol)。426522:水揚酸酯與類 視色素用於皮膚之治療。294656:抗產雄之單環和雙環烯烴。222591. 用以調節皮膚皺紋及/或皮膚老化之N-乙醯基一L一半胱胺酸及豆衍生 物。173885··類視黃素及含彼等之藥劑。 f 美國專利公告編號： 6，413,526化妝品和/及皮膚科組合物分散聚合物系統和用這系統作 為緊縮劑(Cosmetic and/or dermatological composition comprising a dispersion of a polymer system, and use of this system as a tensioning agent) 6,180,133抗氧化劑組合物之經皮吸收劑做為預防和去皺紋 (Antioxidant composition for topical/transdermal prevention and treatment of wrinkles)。所使用的成分僅為檸檬酸，乙醇酸，乳酸及蘋 果酸。 、 6,001,367化妝品和/及皮膚科組合物分散聚合物系統和用這系統作 為緊縮劑(Cosmetic and/or dermato丨ogical composition containing a dispersion of a polymeric system and use of this system as tensor) 本紙張尺度逋用中國國家標隼（CNS ) Λ4規格（210X297公缝） ---------丨裝-------訂------線 (請先閱讀背面之注意事項再填寫本頁各櫊) 200407167 經濟部智慈財產局員工消費合作社印製 Α7 Β7 五、發明説明（三）㈢ 足 喝 ^, a person's nutritional intake ΐί; lose; Qi = J. Yin Ersu 52, a multi-faceted article, the pulse is condensed, printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs (^ f, fir; iirr ^ (v)! J ^ f 3 Causes stasis of f, stagnation of blood, mixed veins on the top, which means that the facial skin loses blood support and wrinkles. The top and bottom lines are the result of skin aging, which is irresistible, but it ’s not natural ί ^ ίίΐΐΙ ' & butterfly_ &, Na Naji: its health care is not embarrassing, old and wrinkled, whitish teeth fall, face two and two right " b use Yishen filling essence, nourishing qi and blood, Recipes that nourish the spleen and stomach, and promote blood circulation and delight the face, can be used for long-lasting, anti-aging and anti-wrinkle. 、 Public Republic of China Patent Bulletin No. 491710 ^: Hydroxyl fatty acid amidoamine and visual network that control keratinocyte differentiation Pharmaceutical composition of alcohol Retinyl amidin. 480178: Cosmetic composition containing resveratrol. 448161: cyclic amidine derivative. 445252: vitamin D3 analogue 12-hydroxyl-6-ene-23 -Acetylene-20-epi-cholecalciferol (choleca 丨 ciferol). 426522: Salicylates and retinoids are used in the skin Treatment. 294656: Monocyclic and bicyclic olefins that are resistant to male sex. 222591. N-Ethyl-L-cysteine and soy derivatives for regulating skin wrinkles and / or skin aging. 173885 ·· Retinoids And their containing agents. F U.S. Patent Publication No. 6,413,526 Cosmetic and / or dermatological composition dispersing polymer system and using this system as a tightening agent (Cosmetic and / or dermatological composition comprising a dispersion of a polymer system, and use of this system as a tensioning agent) 6,180,133 Antioxidant composition for topical / transdermal prevention and treatment of wrinkles. The only ingredients used are citric acid, ethanol Acid, lactic acid and malic acid. 6,001,367 Cosmetic and / or dermatological composition dispersing polymer system and using this system as a tightening agent (Cosmetic and / or dermato 丨 ogical composition containing a dispersion of a polymeric system and use of this system as tensor) This paper uses China National Standard (CNS) Λ4 size (210X297 cm) --- ------ 丨 Installation ------- Order ------ Line (Please read the notes on the back before filling in each page of this page) 200407167 Printed by the Employee Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Α7 Β7 V. Description of the Invention (3)
Meth〇ds and C-P〇^ti〇ns and —etic 5,054,143 抗皺枕頭（Anti-wrinkle pillow) 4,552,295抗敏設備（/\帥省毗丨6扣化句 以上不論中華民國或美國的專利，均與本發 [發明欲解決旳課題] /、个乂 1，、、即 ，大致都以已知的化合物的成☆’所組合而成 化妝口 去”宣稱。但從中藥的瞭解’僅以單一成分的 物’其功效疋有限的。而且可能有副作用。中醫用來做美 全株或多味的方劑。其缺點在製作及處理的過程粗 述缺乏實證。同時由於時代的不同，往曰《普濟 二Ρί //ί$、工k蹄膀作為豐臉良方，已經太普遍了，而不再算是。 =《，聖“治眉鬃u羊糞__·.· ’於馬糞冗二曰 樂成。作為基質材料不再能被接受。 [為解決課題所採之手段] ίί中化物及S〇D的含量較高，具有清除人體内過多氧自由基 抗皺、防曬及抗衰老中亦有特殊功效。本發明以抗氧化及 估’來證明所採用的中藥材其產生抗皱消紋的依據，厂 二使=現代的化妝品賦形劑，使含中藥的抗皺消紋化妝品之品質 t療1賴驗美的的皮膚彈力儀器，評估含抗㈣紋的化妝品之臣 H 抗氧化力活性試驗採用Arnao研究的ABTS/ 分㈣統，作為抗氧化難分析。抗祕物具有清除自 間藉 季乂出總抗乳化力活性的大小。 ^ 古士，起^支化晦活性試驗以NBT (nitroblue tetrazolium)當指示未 白:hl^nine當催化劑，當「iboflavin照光後會產生超氧自由基 二，丁，使原本淡觀氧化態NBT變成深藍色還乂 二和有似超乳歧化梅活性存在則會抑制NBT被還原，定』 起虱支化晦活性1U為抑制50% NB丁被還原的量。 本紙狀反通财_家標準（CNS) Μ規格（2丨以297公瘦 m «ml n^— 1>11 urn—— —^ϋ ml ^ΒΓ V .^m·· m-ϋ «.1.——— ml* —.mi n·—— V (請先間讀背面之注意事項再填寫本頁) 200407167 kl B7 五Meth〇ds and CP〇 ^ ti〇ns and —etic 5,054,143 Anti-wrinkle pillow 4,552,295 anti-sensitivity equipment [Inventive problem to be solved] /, I, I, i.e., are generally made of known compounds ☆ 'combined to make up the mouth' claim. But from the understanding of traditional Chinese medicine 'only a single ingredient 'Its efficacy is limited. And there may be side effects. Traditional Chinese medicine is used to make whole or multi-flavored prescriptions. Its shortcomings are lack of evidence in the process of production and processing. At the same time, due to the different times, "Puji II Ρί // ί $, the workman's hoof as a good recipe for the face, it is too common, and it is no longer counted. = ", St." Growing eyebrows and sheep manure __ ·. · 'Yu Ma Fei redundant two Yuecheng . As a matrix material can no longer be accepted. [Methods adopted to solve the problem] The high content of Chinese compounds and SOD has a special effect in removing excess oxygen free radicals in the human body, anti-wrinkle, sun protection and anti-aging. The present invention demonstrates the use of The basis of its anti-wrinkle and wrinkle reduction, factory two make = modern cosmetic excipients, so that the quality of anti-wrinkle and wrinkle-free cosmetics containing traditional Chinese medicine t treatment 1 rely on the skin elasticity of beauty inspection equipment, evaluation of anti-wrinkle cosmetics minister H Antioxidant activity test uses the ABTS / bifurcation system studied by Arnao, which is difficult to analyze for antioxidants. Anti-secrets have the ability to clear the total anti-emulsifying activity from the seasons. ^ Gushi, Qi In the activity test, NBT (nitroblue tetrazolium) is used to indicate that it is not white: hl ^ nine is used as a catalyst. When "iboflavin is irradiated with light, superoxide radicals II and D will be produced, which will cause the original lightly oxidized NBT to become dark blue. The presence of super milk disperse plum activity will inhibit the reduction of NBT. It is determined that the lice branching activity 1U is the amount that inhibits the reduction of 50% of NB. This paper-shaped anti-wealth standard (CNS) M specifications (2 丨 to 297 male thin m «ml n ^ — 1 > 11 urn—— — ^ ϋ ml ^ ΒΓ V. ^ M ·· m-ϋ« .1 .——— ml * —.mi n · —— V (please first (Notes on the back of the occasional reading, please fill out this page) 200407167 kl B7 5
、發明説明（阳） tyrosinase ^ mushroom 量分析盤孔素^/析儀_培養前、後每一格微 利用下列公气°^1 ( nm ’ microplate「eade「）。 」A式计异出酪胺酸晦活性的抑制率： •nh(%) -[((D-C)-(b-A))/(D-C)] A、R ·丄、-.J 100 % A、R •丄 、 ,λ^ y j x 1〇〇 C、D : 1培養前：後所測出的吸光值； /Ν°式k口口，培養前、後所測出的 ί 級氧化力活性_酸晦活性抑制率與似超氧歧 之結果 1化力活性路胺酸晦活性抑制率與似超氧歧化腾活性 植物名超氧歧化liF 9 性(U/g 新鮮重） 28800^---- 17100 ,袭—· (請先閱讀背面之注意事項再填寫本頁) 經 濟 部 智 慧 財 產 局 消 費 合 作 社 印 製 欖仁掏· 牡丹皮 女貞子 桑葉 白芍 知母 生地黃 明曰葉 益母草 、細辜 樟芝 綠豆 ί本 桑白皮 白芷 紫色高麗菜 乾燥香菇 油菜 显智仁 當歸 才土 {令 洋萍 6220 5070 4910 3990 2420 1890 1630 1260 1200 926 901 850 817 1217 761 710 568 567 561 559 本纸狀度賴悄 67560 46403 113915 35612 21805 5524 42722 12600 9563 106428 9923 11933 3148 9042 22311 28118 5223 5018 103880 4608 17506 609Ϊ9 赂胺酸酶活 性抑制率(〇/0) ~96^2 73.89 77.21 44.87 54.08 42.25 45.35 40.99 28.92 39.54 47.41 52.38 64.25 6978 54.11 29.95 35.43 64.26 48.25 48.51 55.97 -I..... I - - - I I · 200407167 A7 B7 五、發明説明（复） 經濟部智慧財產局員工消費合作社印製 合歡皮 522 12389 55.71 蒺藜 516 5697 52.72 龍眼 475 14514 64.85 洋蔥 446 5310 48.47 菠菜 434 5502 39.55 白 朮 471 41426 45.05 菟絲子 466 30572 防風 460 6222 38.14 麥門冬 411 1705 53.91 威靈仙 372 12779 54.52 栝蔞實 352 6727 58.84 豌豆芽 296 15400 53.28 黨參 291 6528 53.13 桔梗 289 - 63.76 綠豆芽子葉 243 4871 44.26 桃仁 233 - 67.54 苦,/fv_ 228 5243 44 R3 蕃茄 143 10250 41.68 蘿蔔 169 14700 35.64 辛夷 181 11277 31.37 山慈菇 179.83 4801 44.78 白蔹 163 - 40.37 台灣金線蓮 146 7875 53.54 天門冬 145 1759 71.39 人參 131 1944 47.10 郁李仁 120 424 54.52 結球萵苣 123 5011 46.59 小黃瓜 104 4600 59.64 白果 99.1 3394 47.62 薏it仁 85.1 8734 42.23 冬瓜子 52.〇 6247 56.33 杏仁 47.1 - 41.51 牛蒡 755 7160 33.25 黃豆芽子葉 79 5015 48.57 半夏 29.7 - 37.83 (請先閱讀背面之注意事項再填寫本頁) 太抓路疮；杰田由闻聞亡括1准/ r>\IC、Λ «r /，1 200407167、 Explanation of the invention (yang) tyrosinase ^ mushroom Quantitative analysis of plate porin ^ / analyzer _ Before and after the culture, each cell uses the following public gas ° ^ 1 (nm 'microplate 「eade」). "A type meter difference case Inhibition rate of amino acid activity: • nh (%)-[((DC)-(bA)) / (DC)] A, R · 丄, -.J 100% A, R • 丄,, λ ^ yjx 100C, D: 1 before and after incubation: absorbance measured; / N ° -type k-mouth, ί-level oxidation activity activity_acid activity inhibition rate and super-oxygen-like activity measured before and after incubation Results of disagreement 1 Inhibition rate of chemically active glutamate activity and superoxide disproportionation-like plant name superoxide disproportionation liF 9 properties (U / g fresh weight) 28800 ^ ---- 17100, please — (please first (Please read the notes on the back and fill in this page) Printed by the Cooperative Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs, Peony skin, Ligustrum lucidum, Magnolia spp. Vegetable Dried Shiitake Mushroom Rape Xianzhiren Angelica Talent Land {令 洋 萍 6220 5070 4910 3990 2420 1890 1630 1260 1200 926 901 850 817 1217 761 710 568 567 561 559 Paper-like degree Lai 67560 46403 113915 35612 21805 5524 42722 12600 9563 106428 9923 11933 3148 9042 22311 28118 5223 5018 103880 4608 17506 609Ϊ9 Inhibition rate of bridase activity (〇 / 0) ~ 96 ^ 2 73.89 77.21 44.87 54.08 42.25 45.35 40.99 28.92 39.54 47.41 52.38 64.25 6978 54.11 29.95 35.43 64.26 48.25 48.51 55.97 -I ..... I---II · 200407167 A7 B7 V. Description of the Invention (Re) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Acacia 522 12389 55.71 Tribulus 516 5697 52.72 Longan 475 14514 64.85 Onion 446 5310 48.47 Spinach 434 5502 39.55 Atractylodes 471 41426 45.05 Cuscuta 466 30572 Windproof 460 6222 38.14 Maimendong 411 1705 53.91 Welling Fairy 372 12779 54.52 Tribulum 352 6727 58.84 Pea Sprout 296 15400 53.28 Codonopsis 291 6528 53.13 Platycodon 289-63.76 Mung Bean Sprout Cotyledon 243 4871 44.26 Peach Kernel 233-67.54 Bitter, / fv_ 228 5243 44 R3 Tomato 143 10250 41.68 Radish 169 14700 35.64 Xinyi 181 11277 31.37 Shanci Mushroom 179.83 4801 44.78 White蔹 163-40.37 Taiwan clematis 146 787 5 53.54 Asparagus 145 1759 71.39 Ginseng 131 1944 47.10 Yu Liren 120 424 54.52 Ginkgo lettuce 123 5011 46.59 Gherkin 104 4600 59.64 Ginkgo 99.1 3394 47.62 薏 it 85.1 8734 42.23 Winter melon seeds 52.〇6247 56.33 Almond 47.1-41.51 Burdock 755 7160 33 Soybean sprouts cotyledon 79 5015 48.57 Pinellia 29.7-37.83 (Please read the precautions on the back before filling out this page) Too scratching road sores; Jie Tian You Wen Wen Kuo 1 quasi / r > \ IC 、 Λ «r / ， 1 200407167
茯苓 21.8 4312 49.96 小麥草 6512 17700 69.62 稻米 5423 10300 50.41 花生 5510 11500 48.26 茶葉 8246 154000 89.65 玉竹 一 62.10 本试驗所採用的儀器為Dja_str〇ri公司的DenTiai Torque Meter，選50〜60歲的受試者，男女各3人，使用本發明的製劑〇 3 g， $拭於受試者之前臂上，每人的部位相同。於每次塗藥後2小時測5式，以Dermal Torque Mete「使力15 mNm 15秒，測其即時擴張 度（Ue)。另擇一外無擦藥前臂處為對照，連測5天。以其變化百分比 ^Ue。/。= [Ue(tt)-Ue(ct)]/[Ue(t0)-Ue(c0)]x100% 顯示其皮膚彈力的抗皺效果。 今，有/效性之g品床試驗之受試者、篩選與試驗結果之評估如 (1) 受試者接收標準 名受試者’ 30-40歲之女杪，接受防皺I白的化胳品贺劑。 (2) 實驗方法 … · '* ^式者於，驗開始前需由皮膚科專科醫師先判斷Skin type。 ，试者於試驗開始前及每二週使用防皺美白的化妝品製劑均需回 $門診紀錄臉部色素的變化。使用黑色素及血紅素測定儀 (MexameterMX18)測定臉部黑色素含量。於試驗開始前及第 四週則需利用數位相機於同樣的條件下拍照紀錄。 受試時間維持四周，試驗品每日塗抹半邊臉兩次（早晚各一次） II. III. (請先閲讀背面之注意事項再填寫本頁) 經濟郜智慧財產局員工消費合作社印製 實施例實例一 巧醇3.0〇/〇(w/w)尼泊金曱酯〇 PCA-Na〇5〇/气仆 5·° ^^3.0 % .卡田水餘里至1〇〇 mL。攪拌，冷至室溫即可。 …、抗皱效果 擴張度變化\天數 Λ 1 1 λ/ ' 第1天 ¥2^ 第3天 第4趸 第5天 AUe0/〇 6% 6% 8% 8% 7% 降40%以上/ 的 1Poria 21.8 4312 49.96 Wheatgrass 6512 17700 69.62 Rice 5423 10300 50.41 Peanut 5510 11500 48.26 Tea 8462 154000 89.65 Yuzhu 62.10 The instrument used in this test is the DenTiai Torque Meter of Dja_strori Company, and the test is 50 to 60 Three males and three females, using the preparation of the present invention, 0.3 g, were rubbed on the front arm of the subject, and each person had the same site. Measure 5 at 2 hours after each application, and measure the instantaneous dilation (Ue) with Dermal Torque Mete "for 15 mNm for 15 seconds. Another option is to use a non-abrasive forearm as a control for 5 consecutive days. The percentage of change ^ Ue ./.= [Ue (tt) -Ue (ct)] / [Ue (t0) -Ue (c0)] x100% shows the anti-wrinkle effect of its skin elasticity. Today, it is effective Subjects of g-bed test, screening and evaluation of test results are as follows: (1) Subjects receive standard subjects' son-in-law, 30-40 years old, and receive anti-wrinkle whitening chemicals. 2) Experimental methods ... · For those who are using the "* ^ type", the skin type must be determined by a dermatologist before the test. The tester must use the anti-wrinkle and whitening cosmetic preparation before the test and every two weeks. Record changes in facial pigments. Use melanin and heme analyzer (MexameterMX18) to measure facial melanin content. Before the start of the test and in the fourth week, use a digital camera to take pictures under the same conditions. The test time is maintained for four weeks. The test product is applied to half of the face twice a day (one morning and one evening) II. III. (Please read the precautions on the back before filling this page) Economic, Intellectual Property Bureau, Employee Consumer Cooperative, Printed Example, Example: Alcohol 3.000 / 〇 (w / w) Nipaginate ○ PCA-Na〇50 / Air Servo 5. ° ^^ 3.0%. Water to 100mL. Stir and cool to room temperature.…, The anti-wrinkle effect expansion changes \ days Λ 1 1 λ / 'Day 1 ¥ 2 ^ Day 3 4 趸 Day 5 AUe0 / 〇6% 6% 8% 8% 7% down more than 40% / 1
200407167 五、發明説明（七^ 實例二 六醇 了基苯？醚 0.05% 〇/0 白 # 艿· 〇甘油 12 % Tween-^O 2% Span-60 ——-----一Ll/_^ 玉 j ^B95〇c ^ ^m^-Trn 鐘攪拌下琢:、人i：复f均貝器中乳化2分鐘，然後在80-100轉厂 步冷却，當溫唐降？-45°Γ日人η，：人四日寻 裝-------訂 (請先閲讀背面之注意事項再填寫本頁) 變化\天數 第1天 第2天 第3天 第4天 第5天 LlAUe% " 6% 6% 7% 7% 7% 卒，^^/W)、黃耆萃取液 5% ϊί^〇^25%—' J J25〇/o 蒸餾水6.725% 二聚甘油二硬脂酸酯1.0%氫 巧萬麻油聚氧乙烯醚1.0 %液體石蠟6.ϋ 16醇(J.b%單石i 凡士林2.0%二曱基聚矽氧烷〇」％ /基七谷氨酸鈉0.21%，丁二醇15.0% 抗菌劑0.1% 氫 f化鈉水溶液C 1 % ) 3.0%羥乙烯基聚合物水溶液（1 % )彳5.〇 /〇 蒸餾水餘量至100 mL。 ^備混合A組分得到w/〇乳液，將乳液與B組分混合得到w/〇/W 果該乳液在4〇°C下穩定1個月。 第2天 第3天 第4天 第5天 8°/〇 1〇°/〇 10% 12% 線 lTar 寸？！ nfr i、Γί'ητ rfv/ft mi! ρ έ _A^g^ZZZII^ 8%"""" 10% ~ 10% 白有效性明顯。本防皺美白的化妝品試驗組之組 四周後美 I：含晉下降 40%以上 實例四 棗汁雪花* ----—^ A 蜂，8% 白油7〇/0地蠟3% 米糠油30/◦羊毛脂醇3% 對氫基苯甲酸丁酯0.2% B ?备餾水55%棕櫚酸異丙酯12〇/。界面活性劑2%對羥基 苯甲酸甲酯0.2% C 桃仁萃取液5% 桑荦萃取液4% 香精0.6% 200407167 A7 ____B7_ 五、發明説明（/、） 製備：將A部分、B部分分別混合攪拌加熱至75t，然後將置於乳 化器中進行充分乳化，當溫度降至40°C時加C部分，混合均勻後， 靜止一天後分裝。 抗皺效果 擴張度變化\天數 第1天 第2天 第3天 第4天 第5天 △Ue0/〇 6% 7% 8% 8°/〇 9% 實例五 紫草根乳液 A 蒸餾水75% 界面活性劑0.1% EDTA 0.1% 沒食子酸 丙S旨0.1 % B 甘油4% 白油2.5%蜂堪2.5%單硬酯酸甘油酯1.5%硬 脂酸1 % C 合歡皮萃取液7.5%龍眼萃取液5 %香精0·7% 製備:將B部分分別加入A部分中，攪拌降溫至70°C使其溶解，在攪 拌下將C部分加入A、B部分攪拌至45°C後分裝 抗皺效果 擴張度變化\天數 第1天 第2天 第3天 第4天 第5天 △Ue0/〇 4% 8% 10°/〇 10% 8% 四周後美白有效性明顯。本防皺美白的化妝品試驗組之組織黑色素含 量下降40%以上。 裝 訂 , 線 (請先閱讀背面之注意事項再填寫本頁) 經濟部智慈財產局員工消f合作社印製200407167 V. Description of the invention (Seven examples of hexacosyl phenylbenzene? Ether 0.05% 〇 / 0 白 # 艿 · 〇 glycerol 12% Tween- ^ O 2% Span-60 ——----- Ll / _ ^ Yu j ^ B95〇c ^ ^ m ^ -Trn Cut with agitation :, person i: compound f emulsifier in a homogenizer for 2 minutes, then cool at 80-100 rpm, when the temperature drops -45 ° Γ Day people η: People look for clothes on four days ------- Order (please read the precautions on the back before filling this page) Change \ days 1st day 2nd day 3rd day 4th day 5th LlAUe% " 6% 6% 7% 7% 7% (^^ / W), Scutellaria baicalensis extract 5% ϊί ^ 〇 ^ 25% — 'J J25〇 / o Distilled water 6.725% Diglycerol distearate Acid ester 1.0% Hydrogen sesame oil polyoxyethylene ether 1.0% Liquid paraffin 6. ϋ 16 alcohol (Jb% monolithi Vaseline 2.0% difluorenyl polysiloxane ″ ″ / sodium heptaglutamate 0.21%, Butanediol 15.0% antibacterial agent 0.1% aqueous sodium hydrogen chloride solution C 1%) 3.0% aqueous vinyl vinyl polymer solution (1%) 彳 5.0 / 〇 the remaining amount of distilled water to 100 mL. Prepare the w / 〇 emulsion by mixing the A component, and w / 〇 / W by mixing the emulsion with the B component. The emulsion is stable at 40 ° C for 1 month. Day 2 Day 3 Day 4 Day 5 8 ° / 〇 1〇 ° / 〇 10% 12% line lTar inch? !! nfr i 、 Γί'ητ rfv / ft mi! ρ _A ^ g ^ ZZZII ^ 8% " " " " 10% ~ 10% White is effective. This anti-wrinkle and whitening cosmetic test group has four weeks of beauty I: containing 40% more than Jin, four examples of jujube snowflakes * ---- A bee, 8% white oil 70/0 earth wax 3% rice bran oil 30 / ◦ Lanolin alcohol 3% Butyl p-hydrobenzoate 0.2% B? Prepared distilled water 55% isopropyl palmitate 12〇 /. Surfactant 2% methyl parahydroxybenzoate 0.2% C peach kernel extract 5% mulberry extract 4% flavor 0.6% 200407167 A7 ____B7_ V. Description of the invention (/,) Preparation: Mix part A and part B separately Heat to 75t, then put it in an emulsifier for full emulsification, add part C when the temperature drops to 40 ° C, mix evenly, and distribute it after standing for one day. Anti-wrinkle effect Expansion changes \ days 1st day 2nd day 3rd day 4th day 5 △ Ue0 / 〇6% 7% 8% 8 ° / 〇9% Example five Sorbus root emulsion A distilled water 75% surfactant 0.1% EDTA 0.1% propyl gallate 0.1% B glycerol 4% white oil 2.5% bee 2.5% glyceryl monostearate 1.5% stearic acid 1% C acacia skin extract 7.5% longan extract 5 % Fragrance 0 · 7% Preparation: Add Part B to Part A separately, stir to cool to 70 ° C to dissolve, add Part C to Part A and B under stirring, stir to 45 ° C, and then add the anti-wrinkle effect. Change \ days 1st day 2nd day 3rd day 4th day 5 △ Ue0 / 〇4% 8% 10 ° / 〇10% 8% Whitening effectiveness is obvious after 4 weeks. The melanin content in the anti-wrinkle and whitening cosmetic test group decreased by more than 40%. Binding, Thread (Please read the notes on the back before filling out this page)