TR201913472A2 - Vi̇ldagli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyon - Google Patents
Vi̇ldagli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyonInfo
- Publication number
- TR201913472A2 TR201913472A2 TR2019/13472A TR201913472A TR201913472A2 TR 201913472 A2 TR201913472 A2 TR 201913472A2 TR 2019/13472 A TR2019/13472 A TR 2019/13472A TR 201913472 A TR201913472 A TR 201913472A TR 201913472 A2 TR201913472 A2 TR 201913472A2
- Authority
- TR
- Turkey
- Prior art keywords
- metformin
- vildagliptin
- combination
- coating
- pharmaceutically acceptable
- Prior art date
Links
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 3
- 229960003105 metformin Drugs 0.000 title abstract 3
- SYOKIDBDQMKNDQ-XWTIBIIYSA-N vildagliptin Chemical compound C1C(O)(C2)CC(C3)CC1CC32NCC(=O)N1CCC[C@H]1C#N SYOKIDBDQMKNDQ-XWTIBIIYSA-N 0.000 title abstract 2
- 229960001254 vildagliptin Drugs 0.000 title abstract 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Mevcut buluş; hidroksipropilmetil selüloz veya hidroksipropil selüloz içermeyen bir kaplama ile vildagliptin, metformin veya metforminin farmasötik olarak kabul edilebilir bir tuzunu içeren katı bir oral farmasötik kompozisyon ile ilgilidir.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2019/13472A TR201913472A2 (tr) | 2019-09-06 | 2019-09-06 | Vi̇ldagli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyon |
| EP20860939.6A EP4025194A4 (en) | 2019-09-06 | 2020-08-05 | COMBINATION WITH VILDAGLIPTIN AND METFORMIN |
| PCT/TR2020/050686 WO2021045706A1 (en) | 2019-09-06 | 2020-08-05 | A combination comprising vildagliptin and metformin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2019/13472A TR201913472A2 (tr) | 2019-09-06 | 2019-09-06 | Vi̇ldagli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201913472A2 true TR201913472A2 (tr) | 2021-03-22 |
Family
ID=74852798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/13472A TR201913472A2 (tr) | 2019-09-06 | 2019-09-06 | Vi̇ldagli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyon |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4025194A4 (tr) |
| TR (1) | TR201913472A2 (tr) |
| WO (1) | WO2021045706A1 (tr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022211762A1 (en) * | 2021-03-29 | 2022-10-06 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | The film coated tablet of vildagliptin and metformin hydrochloride |
| CN114886862B (zh) * | 2022-05-17 | 2024-02-02 | 北京悦康科创医药科技股份有限公司 | 一种复方降糖药物制剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009091663A1 (en) * | 2008-01-14 | 2009-07-23 | Phenomix Corporation | Stable pharmaceutical formulation of a dpp-iv inhibitor with metformin |
| EP2295083A1 (de) | 2009-09-15 | 2011-03-16 | Ratiopharm GmbH | Pharmazeutische Zusammensetzung mit den Wirkstoffen Metformin und Sitagliptin oder Vildagliptin |
| TR201010683A1 (tr) * | 2010-12-21 | 2012-07-23 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Vildagliptin formülasyonları. |
| MX2015008427A (es) * | 2012-12-27 | 2015-10-22 | Zentiva Saglik Ürünleri San Ve Tic A S | Proceso de granulacion en seco para producir composiciones de comprimidos de metformina y sus composiciones. |
| EP3512505B1 (en) * | 2016-09-16 | 2023-03-15 | Galenicum Health S.L.U. | Vildagliptin pharmaceutical compositions |
-
2019
- 2019-09-06 TR TR2019/13472A patent/TR201913472A2/tr unknown
-
2020
- 2020-08-05 EP EP20860939.6A patent/EP4025194A4/en active Pending
- 2020-08-05 WO PCT/TR2020/050686 patent/WO2021045706A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4025194A4 (en) | 2023-06-14 |
| WO2021045706A1 (en) | 2021-03-11 |
| EP4025194A1 (en) | 2022-07-13 |
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