TR201700493A2 - FULL AUTOMATIC REMOTE CONTROLLED PERIPHERAL SPREAD ANALYSIS DEVICE - Google Patents
FULL AUTOMATIC REMOTE CONTROLLED PERIPHERAL SPREAD ANALYSIS DEVICE Download PDFInfo
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- 230000002093 peripheral effect Effects 0.000 title claims abstract description 15
- 238000004458 analytical method Methods 0.000 title claims description 3
- 210000004369 blood Anatomy 0.000 claims abstract description 9
- 239000008280 blood Substances 0.000 claims abstract description 9
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 230000006698 induction Effects 0.000 claims description 28
- 230000008878 coupling Effects 0.000 claims description 9
- 238000010168 coupling process Methods 0.000 claims description 9
- 238000005859 coupling reaction Methods 0.000 claims description 9
- 239000002184 metal Substances 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 6
- 210000003743 erythrocyte Anatomy 0.000 abstract description 5
- 238000003745 diagnosis Methods 0.000 abstract 3
- 210000000265 leukocyte Anatomy 0.000 abstract 3
- 208000014951 hematologic disease Diseases 0.000 abstract 2
- 208000032839 leukemia Diseases 0.000 abstract 2
- 206010025323 Lymphomas Diseases 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 210000003651 basophil Anatomy 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 210000003979 eosinophil Anatomy 0.000 abstract 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical group [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 238000011005 laboratory method Methods 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 230000000877 morphologic effect Effects 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 238000010186 staining Methods 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 210000005259 peripheral blood Anatomy 0.000 description 3
- 239000011886 peripheral blood Substances 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Diphosphoinositol tetrakisphosphate Chemical compound OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- WHWDWIHXSPCOKZ-UHFFFAOYSA-N hexahydrofarnesyl acetone Natural products CC(C)CCCC(C)CCCC(C)CCCC(C)=O WHWDWIHXSPCOKZ-UHFFFAOYSA-N 0.000 description 1
- 238000002789 length control Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000011120 smear test Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/248—Base structure objective (or ocular) turrets
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/362—Mechanical details, e.g. mountings for the camera or image sensor, housings
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
Abstract
Buluş konusu ürün aynı anda birden fazla preparat ile uzaktan ve gerçek zamanlı olarak kontrolü sağlanabilen istenilen sayıda kullanıcının erişimine izin verilebilen otomatik odak uzaklığının ayarlanabildiği tam otomatik uzaktan kontrollü periferik yayma analiz cihazı ile ilgilidir. Periferik yayma, hastalardan alınan kan örneklerinin klinik laboratuvarda özel boyalarla (giemsa v.b) boyanarak mikroskop ile lökosit (akyuvar), eritrosit (alyuvar), trombosit (kan pulcuğu) gibi kanın şekilli elamanlarını inceleme tekniğidir. Kısaca bir hematoloji testidir. Hematologların en çok başvurdukları gold standart bir teknik olması hasebi ile oldukça sık bir bir şekilde (başvuran her hastaya sıklığında) kullanılmaktadır. Ayrıca sadece tam kan yaymasından değil, kemik iliği aspiratlarından da periferik yayma benzer bir şekilde yapılabilmektedir. Kandaki lökositlerin (nötrofil, bazofil, lenfosit, eozinofil gibi) yüzdesi ve trombosit ve eritrosit gibi kan hücrelerinin sayı ve şekillerinin incelenmesinde ve kan hastalıklarının tanısında yararlı bilgiler veren güvenilir bir laboratuvar yöntemidir. Değişik kan hastalıklarında (lösemi, lenfoma, anemi vb.) meydana gelen morfolojik bozuklukların saptanmasında kullanılmaktadır. Tanı dışında, hastanın tedaviye verdiği cevabın takibinde ve lösemi vakalarında nükslerin gösterilmesinde de sağlıklı bilgiler vermektedir. Periferik yayma analiz cihazı hematoloji uzmanı olsun ya da olmasın hemen her hastanede kullanılabilir bir cihazdır. Uzaktan kontrolü mümkün kıldığı için hastaların merkezinde tetkik edilmesinin de önünü açar. Bu bağlamda toplum sağlığı merkezlerinde de ihtiyaç olabilecek bir cihazdır. Toplum sağlığı merkezlerinin bağlı bulundukları laboratuvar ortamlarında da bulunabilecek mahiyette bir cihazdır. Benzer şekilde yetkilendirme yapılan her hematolog tarafından uzaktan kontrol edilerek teşhis/kontrol için kullanılabilir.The product of the present invention relates to a fully automated remote controlled peripheral smear analyzer, in which a desired number of users can be allowed to be accessed remotely and in real time by means of more than one preparation at a time. Peripheral smear is a technique of staining blood samples from patients with special dyes (giemsa, etc.) in the clinical laboratory and examining the shape of blood such as leukocytes (white blood cells), erythrocytes (red blood cells), platelets (blood pulp). In short, it is a hematology test. Since it is a gold standard technique most commonly used by hematologists, it is used quite frequently (frequency of each patient). In addition, not only whole blood smear but also bone marrow aspirates can be made in a similar manner to peripheral smear. It is a reliable laboratory method that provides useful information on the percentage of leukocytes in the blood (such as neutrophils, basophils, lymphocytes, eosinophils) and the number and shapes of blood cells such as platelets and erythrocytes and in the diagnosis of blood diseases. It is used for the detection of morphological disorders in various blood diseases (leukemia, lymphoma, anemia, etc.). Apart from the diagnosis, it also provides healthy information for the follow-up of the patient's response to treatment and for the recurrence of leukemia cases. The peripheral smear analyzer is a device that can be used in almost any hospital, with or without a hematologist. As it enables remote control, it also paves the way for the patients to be examined at the center. In this context, it is a device that may be needed in community health centers. It is a device that can be found in the laboratory environments of the community health centers. Similarly, it can be remotely controlled by each authorized hematologist and used for diagnosis / control.
Description
TEKNIK ALAN Bulus konusu ürün ayni anda birden fazla preparat ile uzaktan ve gerçek zamanli olarak kontrolü saglanabilen Istenilen sayida kullanicinin erisimine izin verilebilen otomatik odak uzakliginin ayarlanabildigi tam otomatik uzaktan kontrollü periferik yayma analiz cihazi ile ilgilidir. TECHNICAL FIELD The product of the invention can be used with more than one preparation at the same time, remotely and in real time. can be controlled as a desired number of users can be allowed to access fully automatic remote control peripheral with auto focal length adjustable relates to the smear analyzer.
TEKNIGIN BILINEN DURUMU Uluslararasi bilimsel literatürde de tasarim ve imalata yönelik motorize mikroskop sistemleri yok denecek kadar azdir. Benzer çalismalardan bazilari söyledir; (Amirunidzam, “Auto Focus Microscope: Motorized Microscope Focus Controller”, University of Technology Malaysia (UTM), 2014), yaptigi çalismada, otomatik odaklama yapabilen bir motorize mikroskop sistemi tasarlamistir. Çalismada tercih ettikleri “81 Advanced Series” isik mikroskobu ve sistemin kontrolü için Arduino UNO gelistirme karti kullanilmistir. Motor olarak Tek kutuplu (Unipolar) Step Motor (Minibea MO-STEP-17PM-J3X) tercih edilmistir. Kamera olarak ise “Veho VMS- 001” 3-mega piksel ve 200X büyütme yapabilen bir cihaz kullanilmistir. (Tomari vd. “Computer Aided System for Red Blood Cell Classification in Blood Smear görüntülerinden eritrosit bulma ve tanima sürecini otomatiklestirmek için bilgisayar destekli bir motorize isik mikroskobu sistemi (40X'Iik DinoEye mercekli kamera ile) gelistirmislerdir. Ancak Amirunidzam, Tomari ve digerlerinin kullandiklari mikroskobun ticari bir ürün olmasi nedeniyle gelistirilmesi mümkün olmamakla beraber, birçok yönden tasarima baglik olarak mekanik kisitlamalar bulunmaktadir. KNOWN STATE OF THE TECHNIQUE Motorized microscope for design and manufacture in the international scientific literature. systems are scarce. Some of the similar studies are as follows; (Amirunidzam, “Auto Focus Microscope: Motorized Microscope Focus Controller”, University of Technology Malaysia (UTM), 2014), in its study, designed a motorized microscope system that can focus. Preference in the study Arduino for the control of the “81 Advanced Series” light microscope and system UNO development board is used. Unipolar Stepper Motor as Motor (Minibea MO-STEP-17PM-J3X) is preferred. As a camera, “Veho VMS- A device capable of 001” 3-mega pixels and 200X magnification was used. (Tomari et al. “Computer Aided System for Red Blood Cell Classification in Blood Smear computer to automate the process of finding and recognizing erythrocytes from images an assisted motorized light microscope system (with a 40X DinoEye lens camera) they have developed. However, the ones used by Amirunidzam, Tomari and others. Since the microscope is a commercial product, it is not possible to develop it. However, mechanical constraints in many ways depend on the design. are available.
(Campbell vd. “Openstage: A Low-Cost Motorized Microscope Stage with Sub- kabiliyeti olan ve üç eksende hareket edebilen bir mikroskop sistemi tasarlamislardir. Hareketli parça kontrolü için step motor kullanmislardir. Bilgisayar haberlesme arabirimi olarak seri port, kullanici arayüzü tasariminda ve kodlamada ise Matlab ile Phyton kullanmislardir. Gelistirdikleri bu sistem piyasa degerinin oldukça altinda üretilmis olmasi iyi bir avantaj saglarken, cihaz yetenekleri bakimindan önermis oldugumuz diger özellikleri (Kamera sistemin için dinamik odak uzakligi kontrolü, uzaktan kontrol, çoklu preparat hücresi) bulunmamaktadir. (Campbell et al. “Openstage: A Low-Cost Motorized Microscope Stage with Sub- A microscope system that has the ability to move in three axes they have designed. They used stepper motor for moving parts control. Computer Serial port as communication interface, in user interface design and coding They used Matlab and Phyton. This system they developed increased the market value. While it is a good advantage that it is produced quite under, the device capabilities Other features we recommend in terms of focal length control, remote control, multi-prep cell).
BULUSUN TANIMI Mevcut bulus yukarida bahsedilen dezavantajlari ortadan kaldirmak ve ilgili teknik alana yeni avantajlar getirmek üzere gelistirilmis bir tam otomatik uzaktan kontrollü periferik yayma analiz cihazi ile ilgilidir. DESCRIPTION OF THE INVENTION The present invention is designed to eliminate the above mentioned disadvantages and a fully automatic remote control developed to bring new advantages to the field. It relates to the controlled peripheral smear analyzer.
Yapilan literatür arastirmalarinda, ulusal çapta gelistirilen bu türden bir mikroskop sistemi bulunmamaktadir. Ülkemizde özellikle saglik sektöründe kullanilan motorize isik mikroskoplari, yurtdisi menseili firmalar tarafindan üretilen mikroskoplardir ve maliyetleri çok yüksektir. Ayrica bu cihazlarin hemen hemen hepsinde tek preparat hücresi bulunmaktadir. Hem ulusal hem de uluslararasi boyutta bakildiginda ise uzaktan kontrol edilebilen tam otomatik bir mikroskop sistemine yapilan arastirmalarda hiç esine rastlanilmamistir. Bunlara ek olarak, kamera sistemi için otomatik odak uzakligi ayarlanabilir olmasi da ayrica bir avantaj saglamaktadir. In the literature research, this kind of microscope developed nationally system does not exist. It is used especially in the health sector in our country. motorized light microscopes are produced by companies of foreign origin. They are microscopes and their cost is very high. Almost all of these devices all contain a single preparation cell. Both national and international When viewed in size, it is a fully automatic microscope that can be controlled remotely. system has not been found in the researches. In addition to these, The fact that the auto focal length can be adjusted for the camera system is also an advantage. provides advantage.
Gelistirilen yazilim açisindan degerlendirildiginde; elektromekanik isik mikroskobunun uzaktan kontrol edilerek, gerçek zamanli (real-time) olarak periferik kan yayma preparatlarinin incelenmesi ve daha öncede belirtildigi gibi Ulusal Hematoloji Hasta Takip Agi - UHHTA'da ilgili uzman hekimler arasinda paylasilmasini saglayan tam otomatik bir yazilim ürünü (tüm sistem olarak bakildiginda) yoktur. When evaluated in terms of the developed software; electromechanical light by remote control of the microscope, real-time (real-time) examination of peripheral blood smear preparations and, as previously stated, National Hematology Patient Follow-up Network - among relevant specialist physicians at UHHTA A fully automated software product (as a whole system) that allows when viewed) does not exist.
Hematoloji uzmanlari bazi durumlarda hastalarina ait periferik kan yaymalarini kendi aralarinda konsültasyona açarak diger hematoloji uzmanlarin görüslerini alma gereksinimi duyabilmektedir. Bu gibi durumlar için ülkemiz saglik kuruluslarinda yasal prosedürler çerçevesinde çözüm üretebilecek herhangi bir sistem mevcut degildir. Tarafimizdan sunulan proje ile, hematoloji uzmanlari internet üzerinden ortak bir noktada bulusabilmekte, hastaya ait verilerin güvenli bir sekilde transferi saglanmakta ve ayni zamanda uzakta bulunan mikroskop sistemini kontrol ederek gerekli olan tüm islemleri yapabilmektedir. Hematology specialists sometimes take peripheral blood smears from their patients. open to consultation among themselves and get the opinions of other hematology specialists may need to receive. Our country is safe for such situations. any company that can produce a solution within the framework of legal procedures in their organizations. system is not available. With the project presented by us, hematology specialists can meet at a common point over the internet, the data of the patient is safe. in a way that is transferred and at the same time the remote microscope It can control the system and perform all necessary operations.
Remisyondaki kontrol hastalarinin rutin periferik yayma tetkilerini yaptirmak için hastalar hematoloji uzmani olan merkezlere gitmek zorundadirlar; bu seyahatleri doktorun muayenesinden çok periferik yaymanin saglikli bir sekilde yapilip yorumlanabilmesi temeline dayanir. Bu ve benzeri durumlari azaltmak, hematoloji uzmanlarinin sayisinin az olmasindan kaynaklanan her merkeze atanamamasindan kaynaklanan doktor bosluklarini doldurmak, var olan dahiliye hekimlerinin ellerini hematolojik hastalarin degerlendirme ve kontrol proseslerinde rahatlatmak ve yerinde konsültasyon gücü saglamak gibi önemli açiklari kapatacaktir. For routine peripheral smear tests of control patients in remission patients have to go to centers with hematology specialists; these trips whether the peripheral smear can be done in a healthy way rather than the doctor's examination. based on interpretation. Reducing these and similar situations, hematology to each center due to the small number of specialists. filling doctor vacancies caused by not being appointed, existing internal medicine physicians' hands in the evaluation and control processes of hematological patients. important deficits such as comforting and providing on-site consultation power. will close.
Gelistirilen cihazin yazilimsal olarak desteklenmesi sonucu, her hastanin kayitlari bir merkez sunucuda depo edileceginden istenildigi zaman erisim kolayligi saglanacaktir. Hastalarin takibi ve yeni tani almis hastalarin daha genis bir doktor popülasyonu tarafindan degerlendirilmesi ve yerinde elektronik konsültasyona müsaade edecek olmasi önemli bir kullanim sahasi daha olusturmaktadir. As a result of the software support of the developed device, the records of each patient Ease of access at any time as it will be stored on a central server will be provided. Follow-up of patients and a wider doctor of newly diagnosed patients evaluation by the population and on-site electronic consultation. The fact that it will allow is another important usage area.
Cihaz asagida zikredilen modülleri içerecek tarzda modifikasyona ugratilarak farkli is dallarinda ayni amaç çevresinde modifike edilebilir; Cihazin tasinabilirligini kolaylastirmak için WiFi ya da 4.5G uyumlu iletisim protokollerini kullanarak mobilitesi daha da arttirilmistir, Gelistirilen cihaz elektromekanik bir mikroskop sistemi oldugundan, isik mikroskobu ile çalisma yapilabilen tüm alanlarda kullanilabilir. Çizimler Yukarida kisaca özetlenen ve asagida daha detayli ele alinan mevcut bulusun uygulamalari, bulusun ekteki çizimlerde betimlenen örnek uygulamalarina basvurarak anlasilabilir. Ancak ekteki çizimlerin yalnizca bu bulusun tipik uygulamalarini betimledigini ve bulus, bu nedenle, diger esit derecece etkili uygulamalara izin verebilecegi için, kapsamini sinirladiginin varsayilmayacagini belirtmek gerekir. The device has been modified to include the modules mentioned below. can be modified around the same purpose in different branches of business; WiFi or 4.5G compatible communication to facilitate device portability its mobility is further increased by using protocols, Since the developed device is an electromechanical microscope system, the light It can be used in all areas where work can be done with a microscope. drawings The present invention, which is briefly summarized above and discussed in more detail below, embodiments of the invention correspond to exemplary embodiments of the invention depicted in the accompanying drawings. can be understood by pressing. However, the accompanying drawings are only typical of this invention. and the invention therefore describes other equally effective applications. not be deemed to limit its scope, as it may allow applications must be specified.
Sekil 1- Gelistirilen cihazin izometrik görünümü, Sekil 2- X-Ekseni iç görüntüsü, Sekil 3- X-Ekseni dis görüntüsü, Sekil 4- Y-Ekseni izometrik görüntüsü, Sekil 5- Y-Ekseni alt görüntüsü, Sekil 6- Z-Ekseni izometrik görüntüsü, Anlasilmayi kolaylastirmak adina, sekillerde ortak olan özdes elemanlari belirtmek için, mümkün hallerde özdes referans numaralari kullanilmistir. Sekiller ölçekli çizilmemistir ve açiklik için basitlestirilebilir. Bir uygulamanin elemanlari ve özelliklerinin daha fazla açiklama lüzum olmaksizin diger uygulamalara faydali bir biçimde dâhil edilebilecegi düsünülmektedir. Çizimlerdeki Detaylarin Açiklanmasi X-Ekseni tablasini ileri ve geri yönde tahrikleyen step motor, X-Ekseni tablasi için al destek ray sistemi, X-Ekseni tablasi ile alt destek ray sistemini birbirine baglayan parça, Mekanik sistem yataklama alt destek parçasi, Vidali mil için rulmanli yatak, X-Ekseni tahrikleme için vidali mil, Vidali mil somunu, Step motor ile vidali mil baglantisini saglayan kaplin, hücreli preparat tablasi, X-Ekseni tablasi, Sigma profil, Metal ayak, Sigma profil sonlandirma kapagi, Kamera sistemi sabitleme ve sonlandirma parçasi, Indüksiyonlu mil sabitleme parçasi, Kamera sistemine dikey eksende kilavuzluk eden indüksiyonlu mil, Y-Ekseni tablasi tahrikleme için vidali mil somunu, Indüksiyonlu milin Y-Eksenine sabitleme parçasi, Lazer Körügün Y-Eksenine sabitleme parçasi, Mikroskop objektifi, Y-Ekseni tablasi, Kamera sistemi odaklamasi için koruyucu lazer körük, Kamera tablasi, Y-Ekseni tahriklemede kilavuzluk eden indüksiyonlu mil somunu, Step motor ile vidali mil baglantisini saglayan kaplin, Dijital kamera, Vidali mil somunu, Kamera sistemini tahrikleme için vidali mil, Mikroskop objektifleri için revolver, Mikroskop objektifi, Indüksiyonlu milin Y-Eksenine sabitleme parçasi, Mikroskop objektifi, Kamera sistemini asagi ve yukari yönde tahrikleyen step motor, Mikroskop objektifi, Indüksiyonlu mil yatagi, Y-Ekseni sisteminin dikey hareketine kilavuzluk eden indüksiyonlu mil, Indüksiyonlu mil somunu, Y-Ekseni tahrikleme için step motor, Vidali mil somunu, Y-Ekseni sisteminin dikey hareketini saglayan vidali mil, Step motor ile vidali mil baglantisini saglayan kaplin, Z-Ekseni tahriklemede kullanilan step motor, Mekanik sistem yataklama alt destek parçasi, Indüksiyonlu mil somunu, Y-Ekseni'ni Z-Ekseni'ne baglantisini saglayan ara baglanti parçasi, Mekanik sistem yataklama alt destek parçasi, Vidali mil yatagi, BULUSUN DETAYLI AÇIKLANMASI Bu detayli açiklamada bulus konusu tam otomatik uzaktan kontrollü periferik yayma analiz cihazi yapilanmasinin tercih edilen alternatifleri, sadece konunun daha iyi anlasilmasina yönelik olarak ve hiç bir sinirlayici etki olusturmayacak sekilde açiklanmaktadir. Figure 1- Isometric view of the developed device, Figure 2- X-Axis interior view, Figure 3- X-Axis external view, Figure 4- Y-Axis isometric view, Figure 5- Y-Axis bottom view, Figure 6- Z-Axis isometric view, To make the figures easier to understand, specify identical elements common to the figures. Identical reference numbers are used where possible. Figures to scale is not drawn and can be simplified for clarity. Elements of an application and a useful application to other applications without the need for further explanation. is considered to be included. Explanation of Details in Drawings Stepper motor that drives the X-Axis table forward and backward, Lower support rail system for X-Axis table, The part that connects the X-Axis table and the lower support rail system, Mechanical system bedding lower support part, Roller bearing for ball screw, Ball screw for X-Axis drive, ball screw nut, Coupling that provides the screw shaft connection with the stepper motor, cell preparation tray, X-Axis table, sigma profile, Metal leg, Sigma profile end cap, Camera system fixing and end part, Induction shaft fixing part, Induction shaft guiding the camera system on the vertical axis, Ball screw nut for Y-Axis table drive, Fixing part of induction shaft to Y-Axis, Fixing part of Laser Bellow to Y-Axis, microscope lens, Y-Axis table, Protective laser bellows for camera system focusing, camera tray, Induction shaft nut guiding Y-Axis drive, Coupling that provides the screw shaft connection with the stepper motor, digital camera, ball screw nut, Ball screw for driving the camera system, revolver for microscope objective, microscope lens, Fixing part of induction shaft to Y-Axis, microscope lens, Stepper motor that drives the camera system up and down, microscope lens, Induction bearing, Induction shaft guiding the vertical movement of the Y-Axis system, induction shaft nut, Stepper motor for Y-Axis drive, ball screw nut, Screw shaft that provides the vertical movement of the Y-Axis system, Coupling that provides the screw shaft connection with the stepper motor, Stepper motor used in Z-Axis drive, Mechanical system bedding lower support part, induction shaft nut, Interconnection piece that connects Y-Axis to Z-Axis, Mechanical system bedding lower support part, ball screw bearing, DETAILED DESCRIPTION OF THE INVENTION In this detailed description, the subject of the invention is fully automatic remote controlled peripheral. Preferred alternatives to smear analyzer configuration are simply for better understanding and will not have any limiting effect is explained in the following.
Periferik kan yayma islemi, hemen hemen tüm saglik kuruluslarinin klinik çalisanlari tarafindan hazirlanabilir olmasina ragmen, inceleme ve degerlendirilme islemlerinin hematoloji uzmanlari tarafindan yapilmasi gerekmektedir. Ancak hematoloji uzmanligi, dâhiliye uzmanliginin bir yan dal ihtisasi olmasi nedeniyle sadece büyük merkezlerde görevlendirilebilmektedir. Bu nedenle sehir merkezleri disinda yasamini sürdüren hastalar ile hematoloji uzmanlari arasinda uzak mesafeler bulunur. Bu durumdaki hastalara ait kan örneklerinin incelenebilmesi için hastalarin hematoloji uzmaninin buldugunu merkeze gelmeleri gerekmektedir. Peripheral blood smear is a clinical practice of almost all healthcare institutions. Although it can be prepared by its employees, examination and evaluation procedures should be performed by hematology specialists. However hematology specialization, since internal medicine specialty is a subspecialty It can only be commissioned in large centers. Therefore, city centers distance between patients living outside the country and hematology specialists. distances exist. Examining blood samples of patients in this condition For this, patients should come to the center what their hematology specialist finds.
Gelistirilen sistemin uzaktan kontrol edilebilir olmasi bu sorunu ortadan kaldiracaktir. Ilgili saglik kurulusu tarafindan hazirlanan kan yayma örnekleri, uzaktaki bir hematoloji uzmani tarafindan internet üzerinden erisim saglayarak analiz islemlerini yapabilecektir. The fact that the developed system can be controlled remotely eliminates this problem. will remove it. Blood smear samples prepared by the relevant health institution, accessed via the Internet by a remote hematology specialist. will be able to do analysis.
Gelistirilen sistem 4 eksenli hareket saglamaktadir. Sekil 2 ve Sekil 3'de detaylari verilen X-Ekseni diger eksenlerden bagimsiz olarak, iki step motor ile ileri ve geri yönde lineer olarak hareket eder. Sekil 4ite detaylari verilen Kamera sistemi Y- Ekseni üzerinde yer almaktadir ve Y-Ekseni tablasinin alt kismina bagli olan step motor ile dikey olarak (yukari ve asagi) hareketi saglanir. Bu hareket ekseninde körük katlanir ya da açilir ve böylece dijital kamera için optimum odak noktasinin belirlenmesini saglar. Sekil 4 ve Sekil 5'te detaylari verilen Y-Ekseni ise Z- Ekseni'ne dikey yönde bagimlidir. Y -Ekseni, Sekil 6'da açiklanan 4 nolu parça (step motor) ile yatay olarak (saga ve sola) hareket ettirilir. Son olarak sekil 6'de Z-Ekseni için dikey yönde (yukari ve asagi) hareketini saglayan parça ise 8 nolu step motordur. The developed system provides 4-axis movement. Details in Figure 2 and Figure 3 The given X-Axis is independent of other axes, forward and backward with two stepper motors. moves linearly in the direction. Camera system Y- It is located on the axis and is connected to the lower part of the Y-Axis table. Vertically (up and down) movement is provided by the motor. In this movement axis the bellows folds or unfolds so that the optimum focus point for the digital camera allows to be determined. The Y-Axis detailed in Figure 4 and Figure 5 is Z- It is vertically dependent on its axis. Y-Axis, part 4 described in Figure 6 It is moved horizontally (right and left) with (stepper motor). Finally in figure 6 The part that provides the vertical (up and down) movement for the Z-Axis is the part number 8 is a stepper motor.
Bulus konusu ürün yukarida anlatilan özelliklere su parçalar yardimiyla X Ekseninde(1), X-Ekseni tablasini ileri ve geri yönde tahrikleyen step m0tor(1.1), X-Ekseni tablasi için al destek ray sistemi(1.2), Aydinlatma sistemi için plaka(1.3), X-Ekseni tablasi ile alt destek ray sistemini birbirine baglayan parça(1.4), Mekanik sistem yataklama alt destek parçasi(1.5), Vidali mil için rulmanli yatak(1.6), X- Ekseni tahrikleme için vidali mil(1.7), Vidali mil somunu(1.8), Step motor ile vidali mil baglantisini saglayan kaplin(1.9), 15 hücreli preparat tablasi(1.10), X-Ekseni tablasi(1.11), Sigma profil(1.12), Metal ayak(1.13), Sigma profil sonlandirma Y Ekseninde(2), Kamera sistemi sabitleme ve sonlandirma parçasi(2.1), Indüksiyonlu mil sabitleme parçasi(2.2), Kamera sistemine dikey eksende kilavuzluk eden indüksiyonlu mil(2.3), Y-Ekseni tablasi tahrikleme için vidali mil somunu(2.4), Indüksiyonlu milin Y-Eksenine sabitleme parçasi(2.5), Lazer Körügün Y-Eksenine sabitleme parçasi(2.6), Mikroskop objektifi(2.7), Y-Ekseni tablasi(2.8), Kamera sistemi odaklamasi için koruyucu lazer körük(2.9), Kamera tablasi(2.10), Y-Ekseni tahriklemede kilavuzluk eden indüksiyonlu mil somunu(2.11), Step motor ile vidali mil baglantisini saglayan kaplin(2.12), Dijital kamera(2.13), Vidali mil somunu(2.14), Kamera sistemini tahrikleme için vidali Indüksiyonlu milin Y-Eksenine sabitleme parçasi(2.18), Mikroskop 0bjektifi(2.19), Kamera sistemini asagi ve yukari yönde tahrikleyen step m0tor(2.20), Mikroskop objektifi(2.21), Z Ekseninde(3), Indüksiyonlu mil yatagi(3.1), Y-Ekseni sisteminin dikey hareketine kilavuzluk eden indüksiyonlu mil(3.2), Indüksiyonlu mil somunu(3.3), Y-Ekseni tahrikleme için step motor(3.4), Vidali mil somunu(3.5), Y-Ekseni sisteminin dikey hareketini saglayan vidali mil(3.6), Step motor ile vidali mil baglantisini saglayan kaplin(3.7), Z-Ekseni tahriklemede kullanilan step motor(3.8), Mekanik sistem yataklama alt destek parçasi(3.9), Indüksiyonlu mil somunu(3.10), Y-Ekseni'ni Z- Ekseni'ne baglantisini saglayan ara baglanti parçasi(3.11), Mekanik sistem yataklama alt destek parçasi(3.12), Vidali mil yatagi(3.13) ulasmaktadir. The product subject to the invention has the above-described features with the help of water parts. In the X-Axis(1), stepper motor(1.1) drives the X-Axis table forward and backward, Lower support rail system (1.2) for X-Axis table, plate (1.3) for lighting system, The part connecting the X-Axis table and the lower support rail system (1.4), Mechanical system bearing lower support piece (1.5), ball bearing for ball screw (1.6), X- Ball screw (1.7), Ball screw nut (1.8), Stepper motor with ball screw for driving the axis coupling providing shaft connection (1.9), 15-cell preparation table (1.10), X-Axis table(1.11), Sigma profile(1.12), Metal foot(1.13), Sigma profile termination On Y Axis(2), Camera system fixing and end piece(2.1), Induction spindle fixation piece(2.2), on the vertical axis to the camera system guiding induction spindle(2.3), ball screw for Y-Axis table drive nut(2.4), Fixing part(2.5) of induction shaft to Y-Axis, Laser Fixing part of bellows to Y-Axis(2.6), Microscope objective(2.7), Y-Axis tray(2.8), Protective laser bellows for camera system focusing(2.9), Camera table(2.10), induction shaft guiding Y-Axis drive Nut (2.11), Coupling (2.12), which connects the stepper motor and the screw shaft, Digital camera(2.13), Ball screw nut(2.14), Screw for driving the camera system Fixing part of induction shaft to Y-Axis (2.18), Microscope lens (2.19), Stepper motor(2.20), which drives the camera system up and down, Microscope lens(2.21), In Z Axis(3), Induction bearing(3.1), vertical movement of Y-Axis system guiding induction shaft(3.2), Induction shaft nut(3.3), Y-Axis stepper motor(3.4) for driving, Ball screw nut(3.5), vertical of Y-Axis system Screw shaft (3.6), which provides the movement of the screw shaft, which provides the connection of the screw shaft with the step motor coupling (3.7), stepper motor (3.8) used in Z-Axis drive, Mechanical system bearing lower support piece(3.9), Induction shaft nut(3.10), Y-Axis Z- Interconnection piece (3.11) that connects it to its axis, Mechanical system bearing lower support piece (3.12), ball screw bearing (3.13) reaches.
Claims (1)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/00493A TR201700493A2 (en) | 2017-01-12 | 2017-01-12 | FULL AUTOMATIC REMOTE CONTROLLED PERIPHERAL SPREAD ANALYSIS DEVICE |
| PCT/TR2018/000005 WO2019035790A2 (en) | 2017-01-12 | 2018-01-10 | Fully automated and remotely controlled analyzer for peripheral smear |
| CA3070857A CA3070857A1 (en) | 2017-01-12 | 2018-01-10 | Fully automated and remotely controlled analyzer for peripheral smear |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2017/00493A TR201700493A2 (en) | 2017-01-12 | 2017-01-12 | FULL AUTOMATIC REMOTE CONTROLLED PERIPHERAL SPREAD ANALYSIS DEVICE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201700493A2 true TR201700493A2 (en) | 2017-07-21 |
Family
ID=64901052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2017/00493A TR201700493A2 (en) | 2017-01-12 | 2017-01-12 | FULL AUTOMATIC REMOTE CONTROLLED PERIPHERAL SPREAD ANALYSIS DEVICE |
Country Status (3)
| Country | Link |
|---|---|
| CA (1) | CA3070857A1 (en) |
| TR (1) | TR201700493A2 (en) |
| WO (1) | WO2019035790A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019182528A3 (en) * | 2017-10-23 | 2019-12-26 | Altiparmak Gida Sanayi Ve Ticaret Anonim Sirketi | Pollen classification system and related method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5818637A (en) * | 1996-02-26 | 1998-10-06 | Hoover; Rex A. | Computerized video microscopy system |
| WO2004025569A2 (en) * | 2002-09-13 | 2004-03-25 | Arcturus Bioscience, Inc. | Tissue image analysis for cell classification and laser capture microdissection |
| US7072103B1 (en) * | 2002-09-27 | 2006-07-04 | Cypress Semiconductor Corporation | Microscope with objective lens position control apparatus |
-
2017
- 2017-01-12 TR TR2017/00493A patent/TR201700493A2/en unknown
-
2018
- 2018-01-10 CA CA3070857A patent/CA3070857A1/en not_active Abandoned
- 2018-01-10 WO PCT/TR2018/000005 patent/WO2019035790A2/en active Application Filing
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019182528A3 (en) * | 2017-10-23 | 2019-12-26 | Altiparmak Gida Sanayi Ve Ticaret Anonim Sirketi | Pollen classification system and related method |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3070857A1 (en) | 2019-02-21 |
| WO2019035790A3 (en) | 2019-03-21 |
| WO2019035790A2 (en) | 2019-02-21 |
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