TR200700154A2 - Preparation of erythropoietin by endogenous gene activation. - Google Patents

Preparation of erythropoietin by endogenous gene activation.

Info

Publication number
TR200700154A2
TR200700154A2 TR2007/00154A TR200700154A TR200700154A2 TR 200700154 A2 TR200700154 A2 TR 200700154A2 TR 2007/00154 A TR2007/00154 A TR 2007/00154A TR 200700154 A TR200700154 A TR 200700154A TR 200700154 A2 TR200700154 A2 TR 200700154A2
Authority
TR
Turkey
Prior art keywords
epo
erythropoietin
human
preparation
endogenous gene
Prior art date
Application number
TR2007/00154A
Other languages
Turkish (tr)
Inventor
Stern Anne
Brandt Michael
Koll Hans
Auer Johannes
Honold Konrad
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Priority to TR2007/00154A priority Critical patent/TR200700154A2/en
Publication of TR200700154A2 publication Critical patent/TR200700154A2/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Buluş, endogen insan eritropoietin geninin aktivasyonundan ötürü, insan EPO'sunun bir farmasötik preparasyon halinde ekonomik biçimde üretilmesine olanak sağlamak üzere eritropoietini (EPO) yeterli miktarlar ve yeterli saflık derecesinde üretebilen insan hücrelerine dairdir. Buluş, aynı zamanda, bu tür insan EPO-üretici hücrelerinin üretilmesi için bir işleme, insan hücreleri içinde endogen EPO geninin aktive edilmesi için DNA-konstruktları ve EPO'nun insan hücrelerinde büyük ölçekte üretimi için bir işleme de dairdir.The invention relates to human cells which, due to activation of the endogenous human erythropoietin gene, are capable of producing erythropoietin (EPO) in sufficient amounts and in sufficient purity to enable the economic production of human EPO as a pharmaceutical preparation. The invention also relates to a process for producing such human EPO-producing cells, DNA constructs for activating the endogenous EPO gene in human cells, and a process for large-scale production of EPO in human cells.

TR2007/00154A 2007-01-12 2007-01-12 Preparation of erythropoietin by endogenous gene activation. TR200700154A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TR2007/00154A TR200700154A2 (en) 2007-01-12 2007-01-12 Preparation of erythropoietin by endogenous gene activation.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2007/00154A TR200700154A2 (en) 2007-01-12 2007-01-12 Preparation of erythropoietin by endogenous gene activation.

Publications (1)

Publication Number Publication Date
TR200700154A2 true TR200700154A2 (en) 2008-09-22

Family

ID=42787816

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2007/00154A TR200700154A2 (en) 2007-01-12 2007-01-12 Preparation of erythropoietin by endogenous gene activation.

Country Status (1)

Country Link
TR (1) TR200700154A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010052754A1 (en) 2010-11-30 2012-05-31 Jürgen Lashöfer Knife holding device for motor-driven knife blades for cutting kebab or gyros meat-pillars, comprises centered metal-middle shaft and traveling paths for fixing knife, where crossbar is positively attached as mechanical carrier

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010052754A1 (en) 2010-11-30 2012-05-31 Jürgen Lashöfer Knife holding device for motor-driven knife blades for cutting kebab or gyros meat-pillars, comprises centered metal-middle shaft and traveling paths for fixing knife, where crossbar is positively attached as mechanical carrier

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