TR200301552A1 - Novel oral pharmacological formulations of rofecoxib. - Google Patents

Novel oral pharmacological formulations of rofecoxib.

Info

Publication number
TR200301552A1
TR200301552A1 TR2003/01552A TR200301552A TR200301552A1 TR 200301552 A1 TR200301552 A1 TR 200301552A1 TR 2003/01552 A TR2003/01552 A TR 2003/01552A TR 200301552 A TR200301552 A TR 200301552A TR 200301552 A1 TR200301552 A1 TR 200301552A1
Authority
TR
Turkey
Prior art keywords
rofecoxib
novel oral
pharmacological formulations
oral pharmacological
formulations
Prior art date
Application number
TR2003/01552A
Other languages
Turkish (tr)
Inventor
Uslu Abdullah
Original Assignee
Nobel İlaç Sanayi̇ Ve Ti̇caret A. Ş.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nobel İlaç Sanayi̇ Ve Ti̇caret A. Ş. filed Critical Nobel İlaç Sanayi̇ Ve Ti̇caret A. Ş.
Priority to TR2003/01552A priority Critical patent/TR200301552A1/en
Priority to PCT/TR2004/000039 priority patent/WO2005025564A1/en
Publication of TR200301552A1 publication Critical patent/TR200301552A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

Bu buluş rofekoksib etken içeren ve bu etken maddenin oral yolla alınmasını sağlayan yeni farmasötik dozaj formlarını hazırlamak için geliştirilen yeni yöntem ile ilgilidir. Geliştirilen bu formülasyon ile rofekoksibin dissolüsyon ve invivo özelliklerine üstünlük kazandırılmıştır.The present invention relates to a novel method for preparing novel pharmaceutical dosage forms comprising rofecoxib agent and for oral administration thereof. With this formulation developed, dissolution and invivo properties of rofecoxib were improved.

TR2003/01552A 2003-09-18 2003-09-18 Novel oral pharmacological formulations of rofecoxib. TR200301552A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2003/01552A TR200301552A1 (en) 2003-09-18 2003-09-18 Novel oral pharmacological formulations of rofecoxib.
PCT/TR2004/000039 WO2005025564A1 (en) 2003-09-18 2004-09-16 Oral pharmaceutical formulations of rofecoxib

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2003/01552A TR200301552A1 (en) 2003-09-18 2003-09-18 Novel oral pharmacological formulations of rofecoxib.

Publications (1)

Publication Number Publication Date
TR200301552A1 true TR200301552A1 (en) 2005-10-21

Family

ID=34311481

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2003/01552A TR200301552A1 (en) 2003-09-18 2003-09-18 Novel oral pharmacological formulations of rofecoxib.

Country Status (2)

Country Link
TR (1) TR200301552A1 (en)
WO (1) WO2005025564A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3883562A4 (en) 2018-11-21 2022-08-03 Tremeau Pharmaceuticals, Inc. Purified forms of rofecoxib, methods of manufacture and use
US10945992B1 (en) * 2019-11-13 2021-03-16 Tremeau Pharmaceuticals, Inc. Dosage forms of rofecoxib and related methods
US11161833B1 (en) 2021-04-09 2021-11-02 Tremeau Pharmaceuticals, Inc. Deuterated etoricoxib, methods of manufacture, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9902889A3 (en) * 1996-05-17 2002-04-29 Merck Frosst Canada & Co Kirkl The use of 3-phenyl-4-(4-methylsulphonyl)-phenyl-2-(5h)-furanone for producing anti inflammatory medicaments and such medicaments
JP2003523954A (en) * 1999-12-08 2003-08-12 ファルマシア コーポレイション Cyclooxygenase-2 inhibitor composition with rapid onset of therapeutic effect
PL363771A1 (en) * 2001-02-27 2004-11-29 Ranbaxy Laboratories Limited Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
WO2003086343A2 (en) * 2002-04-05 2003-10-23 Cadila Healthcare Limited Fast disintegrating oral dosage forms

Also Published As

Publication number Publication date
WO2005025564A1 (en) 2005-03-24

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TR200301552A1 (en) Novel oral pharmacological formulations of rofecoxib.