TR200000618T2 - Gonadotropinlerin dictyostelium'da sentezlenmesi. - Google Patents

Gonadotropinlerin dictyostelium'da sentezlenmesi.

Info

Publication number
TR200000618T2
TR200000618T2 TR2000/00618T TR200000618T TR200000618T2 TR 200000618 T2 TR200000618 T2 TR 200000618T2 TR 2000/00618 T TR2000/00618 T TR 2000/00618T TR 200000618 T TR200000618 T TR 200000618T TR 200000618 T2 TR200000618 T2 TR 200000618T2
Authority
TR
Turkey
Prior art keywords
gonadotropins
dictyostelium
synthesis
gonadotropin
mutants
Prior art date
Application number
TR2000/00618T
Other languages
English (en)
Inventor
Diederik Grootenhuis Peter
Christina Heikoop Judith
Herman Karel Linskens Maarten
Johannes Maria Van Haastert Petrus
Blaauw Mieke
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of TR200000618T2 publication Critical patent/TR200000618T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Bu bulus, Dictyostelium'da sentezlenen gonadotropinlere iliskindir. Gonadotropinlerin bir biyolojik açidan aktif biçimde salgilandigi bulunmustur. Gonadotropinlerin Dictyostelium içinde sentezlenmesi gonadotropin mutantlarinin seçilmesi için kolay bir yol temin etmektedir.
TR2000/00618T 1997-09-08 1998-09-02 Gonadotropinlerin dictyostelium'da sentezlenmesi. TR200000618T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202757 1997-09-08

Publications (1)

Publication Number Publication Date
TR200000618T2 true TR200000618T2 (tr) 2000-09-21

Family

ID=8228713

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00618T TR200000618T2 (tr) 1997-09-08 1998-09-02 Gonadotropinlerin dictyostelium'da sentezlenmesi.

Country Status (16)

Country Link
EP (1) EP1012290A1 (tr)
JP (1) JP2001515721A (tr)
KR (1) KR20010023749A (tr)
CN (1) CN1269834A (tr)
AR (1) AR013468A1 (tr)
AU (1) AU746780B2 (tr)
BR (1) BR9812043A (tr)
CA (1) CA2302647A1 (tr)
HU (1) HUP0004599A3 (tr)
IL (1) IL134589A0 (tr)
NO (1) NO20001178L (tr)
NZ (1) NZ502964A (tr)
PL (1) PL339259A1 (tr)
TR (1) TR200000618T2 (tr)
WO (1) WO1999013081A1 (tr)
ZA (1) ZA987497B (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
WO2002002597A2 (en) * 2000-06-30 2002-01-10 Maxygen Aps Peptide extended glycosylated polypeptides
AU2002324183B2 (en) * 2001-09-12 2007-10-25 Merck Serono Sa Use of hCG and LH in controlled ovarian hyperstimulation
MEP39208A (en) * 2001-09-12 2011-02-10 Merck Serono Sa USE OF hCG IN CONTROLLED OVARIAN HYPERSTIMULATION
DE60238490D1 (de) * 2001-09-12 2011-01-13 Merck Serono Sa Verwendung von humanem choriongonadotropin (hcg) und luteinisierendem hormon (lh) zur regulierten hyperstimulation der eierstöcke
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2183564C (en) * 1994-02-18 2010-07-13 William R. Moyle Methods for altering fertility
US5691455A (en) * 1995-10-24 1997-11-25 Akzo Nobel N.V. Gonadotropins with non-native disulfide bridges

Also Published As

Publication number Publication date
WO1999013081A1 (en) 1999-03-18
CN1269834A (zh) 2000-10-11
BR9812043A (pt) 2000-10-03
AR013468A1 (es) 2000-12-27
NZ502964A (en) 2001-08-31
AU9538198A (en) 1999-03-29
AU746780B2 (en) 2002-05-02
EP1012290A1 (en) 2000-06-28
ZA987497B (en) 1999-02-23
PL339259A1 (en) 2000-12-04
NO20001178D0 (no) 2000-03-07
HUP0004599A3 (en) 2002-09-30
NO20001178L (no) 2000-05-05
CA2302647A1 (en) 1999-03-18
KR20010023749A (ko) 2001-03-26
JP2001515721A (ja) 2001-09-25
HUP0004599A2 (hu) 2001-04-28
IL134589A0 (en) 2001-04-30

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