TNSN02023A1 - PYRAZOLOPYRIMIDINE DERIVATIVES NOVEL cGMP-PDE INHIBITORS AND COMPOSITIONS CONTAINING THEM. - Google Patents

PYRAZOLOPYRIMIDINE DERIVATIVES NOVEL cGMP-PDE INHIBITORS AND COMPOSITIONS CONTAINING THEM.

Info

Publication number
TNSN02023A1
TNSN02023A1 TNTNSN02023A TNSN02023A TNSN02023A1 TN SN02023 A1 TNSN02023 A1 TN SN02023A1 TN TNSN02023 A TNTNSN02023 A TN TNSN02023A TN SN02023 A TNSN02023 A TN SN02023A TN SN02023 A1 TNSN02023 A1 TN SN02023A1
Authority
TN
Tunisia
Prior art keywords
compositions containing
pde inhibitors
cgmp
pyrazolopyrimidine derivatives
novel cgmp
Prior art date
Application number
TNTNSN02023A
Other languages
French (fr)
Inventor
Moira Norfor Allerton Charlotte
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of TNSN02023A1 publication Critical patent/TNSN02023A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'INVENTION CONCERNE UN COMPOSE DE FORMULE GENERALE I : DANS LAQUELLE R1 REPRESENTE H OU UN RADICAL ORGANIQUE. ELLE CONCERNE EGALEMENT UNE COMPOSITION LE CONTENANT. APPLICATION : UTILISATION DE CE COMPOSE OU DE CETTE COMPOSITION COMME INHIBITEUR DE cGMP-PDE, NOTAMMENT DE cGMP-PDE5, DANS LE TRAITEMENT CURATIF ET LE TRAITEMENT PROPHYLACTIQUE DE DIVERS ETATS PATHOLOGIQUES.The invention relates to a compound of general formula I: in which R1 represents H or an organic radical. IT ALSO CONCERNS A COMPOSITION CONTAINING IT. APPLICATION: USE OF THIS COMPOUND OR OF THIS COMPOSITION AS INHIBITOR OF cGMP-PDE, IN PARTICULAR OF cGMP-PDE5, IN THE CURATIVE AND PROPHYLACTIC TREATMENT OF VARIOUS PATHOLOGICAL CONDITIONS.

TNTNSN02023A 2001-03-09 2002-03-08 PYRAZOLOPYRIMIDINE DERIVATIVES NOVEL cGMP-PDE INHIBITORS AND COMPOSITIONS CONTAINING THEM. TNSN02023A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0105893.2A GB0105893D0 (en) 2001-03-09 2001-03-09 Pharmaceutically active compounds

Publications (1)

Publication Number Publication Date
TNSN02023A1 true TNSN02023A1 (en) 2005-12-23

Family

ID=9910362

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN02023A TNSN02023A1 (en) 2001-03-09 2002-03-08 PYRAZOLOPYRIMIDINE DERIVATIVES NOVEL cGMP-PDE INHIBITORS AND COMPOSITIONS CONTAINING THEM.

Country Status (8)

Country Link
AP (1) AP2002002462A0 (en)
GB (1) GB0105893D0 (en)
GT (1) GT200200044A (en)
HN (1) HN2002000050A (en)
PA (1) PA8541101A1 (en)
PE (1) PE20021153A1 (en)
TN (1) TNSN02023A1 (en)
WO (1) WO2002072586A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
NZ539972A (en) 2002-12-13 2008-05-30 Warner Lambert Co Alpha-2-delta ligand to treat lower urinary tract symptoms
EP1653966A1 (en) * 2003-07-16 2006-05-10 Pfizer Limited Treatment of sexual dysfunction
ES2646326T3 (en) 2005-08-03 2017-12-13 Sprout Pharmaceuticals, Inc. Use of flibanserin in the treatment of obesity
EP1945214A1 (en) 2005-10-29 2008-07-23 Boehringer Ingelheim International GmbH Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
EP2037927B1 (en) 2006-06-30 2010-01-27 Boehringer Ingelheim International GmbH Flibanserin for the treatment of urinary incontinence and related diseases
AR062320A1 (en) 2006-08-14 2008-10-29 Boehringer Ingelheim Int FLIBANSERIN FORMULATIONS AND METHOD TO MANUFACTURE THEM
AR062321A1 (en) 2006-08-25 2008-10-29 Boehringer Ingelheim Int CONTROLLED RELEASE SYSTEM AND METHOD TO MANUFACTURE
CL2008002693A1 (en) 2007-09-12 2009-10-16 Boehringer Ingelheim Int Use of flibanserin for the treatment of selected vasomotor symptoms of hot flashes, night sweats, mood swings, and irritability
CA2686480A1 (en) 2008-12-15 2010-06-15 Boehringer Ingelheim International Gmbh New salts

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS50011B (en) * 1998-04-20 2008-09-29 Pfizer Inc., Pyridine-3-carboxylic acid derivatives and their use as intermediates
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
IL149025A0 (en) * 1999-10-11 2002-11-10 Pfizer 5-(2-substituted-5-heterocyclylsulphonylpyrid-3-yl)-dihydropyrazolo [4, 3-d] pyrimidin-7-ones as phosphodiesterase inhibitors
CO5271697A1 (en) * 2000-01-12 2003-04-30 Pfizer Prod Inc COMPOSITIONS AND PROCEDURES FOR THE TREATMENT OF AFFECTIONS THAT RESPOND TO AN INCREASE OF TESTOSTERONE

Also Published As

Publication number Publication date
PA8541101A1 (en) 2003-11-12
GT200200044A (en) 2002-12-02
GB0105893D0 (en) 2001-04-25
HN2002000050A (en) 2002-09-13
AP2002002462A0 (en) 2002-06-30
WO2002072586A1 (en) 2002-09-19
PE20021153A1 (en) 2002-12-17

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