TN2014000085A1 - Substituted annellated pyrimidine and the use thereof - Google Patents
Substituted annellated pyrimidine and the use thereofInfo
- Publication number
- TN2014000085A1 TN2014000085A1 TNP2014000085A TN2014000085A TN2014000085A1 TN 2014000085 A1 TN2014000085 A1 TN 2014000085A1 TN P2014000085 A TNP2014000085 A TN P2014000085A TN 2014000085 A TN2014000085 A TN 2014000085A TN 2014000085 A1 TN2014000085 A1 TN 2014000085A1
- Authority
- TN
- Tunisia
- Prior art keywords
- pyrimidine
- prophylaxis
- treatment
- annellated
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present application relates to new substituted annellated pyrimidines, a method for the production thereof, the use thereof in isolation or in combination for the treatment and/or prophylaxis of diseases, and the use thereof to produce medicines for the treatment and/or prophylaxis of diseases, more particularly for the treatment and/or prophylaxis of cardiovascular diseases.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE201210200351 DE102012200351A1 (en) | 2012-01-11 | 2012-01-11 | New substituted annellated pyrimidine compounds are guanylate cyclase stimulators useful to treat and/or prevent heart failure, hypertension, ischemia, vascular disease, renal failure, thromboembolic disorders and fibrotic diseases |
PCT/EP2012/066876 WO2013030288A1 (en) | 2011-09-02 | 2012-08-30 | Substituted annellated pyrimidine and the use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2014000085A1 true TN2014000085A1 (en) | 2015-07-01 |
Family
ID=48652673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2014000085A TN2014000085A1 (en) | 2012-01-11 | 2014-02-28 | Substituted annellated pyrimidine and the use thereof |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE102012200351A1 (en) |
TN (1) | TN2014000085A1 (en) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9314412D0 (en) | 1993-07-13 | 1993-08-25 | Rhone Poulenc Agriculture | New compositions of matter |
DE19642255A1 (en) | 1996-10-14 | 1998-04-16 | Bayer Ag | Use of 1-benzyl-3- (substituted-hetaryl) fused pyrazole derivatives |
DE19834047A1 (en) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituted pyrazole derivatives |
DE19834044A1 (en) | 1998-07-29 | 2000-02-03 | Bayer Ag | New substituted pyrazole derivatives |
JP4197073B2 (en) | 1999-08-27 | 2008-12-17 | 株式会社コスモ総合研究所 | Deep desulfurization catalyst, method for producing the same, and desulfurization method using the same |
DE10220570A1 (en) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamate-substituted pyrazolopyridines |
DE10232571A1 (en) | 2002-07-18 | 2004-02-05 | Bayer Ag | 4-amino substituted pyrimidine derivatives |
AU2004236085B2 (en) | 2003-05-09 | 2010-03-25 | Asahi Glass Company, Limited | Processes for producing 3-substituted 2-chloro-5-fluoropyridine or salt thereof |
CN100355732C (en) | 2003-11-03 | 2007-12-19 | 上海药明康德新药开发有限公司 | Preparation of 2-Cl-5-F-nicotinate and nicotonic acid |
JP4879988B2 (en) | 2005-09-29 | 2012-02-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
NZ582879A (en) | 2007-07-31 | 2012-03-30 | Vertex Pharma | Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
EP2373317B1 (en) | 2008-11-25 | 2016-12-14 | Merck Sharp & Dohme Corp. | 4-amino-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one or 4-amino-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one derivatives as activators of the soluble guanylat cyclase for the treatment of cardiovascular diseases |
JP5409961B2 (en) | 2010-05-27 | 2014-02-05 | メルク・シャープ・エンド・ドーム・コーポレイション | Soluble guanylate cyclase activator |
-
2012
- 2012-01-11 DE DE201210200351 patent/DE102012200351A1/en not_active Withdrawn
-
2014
- 2014-02-28 TN TNP2014000085A patent/TN2014000085A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE102012200351A1 (en) | 2013-07-11 |
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