TN2011000672A1 - Otamixaban for treatment of elderly and renal impaired non st-elevation myocardial patients - Google Patents

Otamixaban for treatment of elderly and renal impaired non st-elevation myocardial patients

Info

Publication number
TN2011000672A1
TN2011000672A1 TNP2011000672A TN2011000672A TN2011000672A1 TN 2011000672 A1 TN2011000672 A1 TN 2011000672A1 TN P2011000672 A TNP2011000672 A TN P2011000672A TN 2011000672 A TN2011000672 A TN 2011000672A TN 2011000672 A1 TN2011000672 A1 TN 2011000672A1
Authority
TN
Tunisia
Prior art keywords
elderly
treatment
otamixaban
elevation myocardial
impaired non
Prior art date
Application number
TNP2011000672A
Inventor
Jens Stechl
Angele Moryusef
Christophe Gaudin
Moury Pascale Ythier
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/060615 external-priority patent/WO2011012527A1/en
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of TN2011000672A1 publication Critical patent/TN2011000672A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the use of (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl) benzoylamino]-butyric acid methyl ester or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for use in non-ST elevation myocardial infarction, said treatment comprising administering a therapeutically effective amount of (2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl) benzoylamino]-butyric acid methyl ester or a pharmaceutically acceptable salt thereof to a human patient, who is elderly and/or shows renal insufficiency and/or has a low body weight.
TNP2011000672A 2009-07-29 2011-12-27 Otamixaban for treatment of elderly and renal impaired non st-elevation myocardial patients TN2011000672A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09290601 2009-07-29
PCT/EP2010/060615 WO2011012527A1 (en) 2009-07-29 2010-07-22 Otamixaban for treatment of elderly and renal impaired non-st elevation myocardial infarction patients

Publications (1)

Publication Number Publication Date
TN2011000672A1 true TN2011000672A1 (en) 2013-05-24

Family

ID=41213432

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2011000672A TN2011000672A1 (en) 2009-07-29 2011-12-27 Otamixaban for treatment of elderly and renal impaired non st-elevation myocardial patients

Country Status (1)

Country Link
TN (1) TN2011000672A1 (en)

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