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Priority claimed from PCT/EP2009/058940external-prioritypatent/WO2010007034A1/en
Application filed by Novartis AgfiledCriticalNovartis Ag
Publication of TN2010000600A1publicationCriticalpatent/TN2010000600A1/en
The invention relates to the use of a pyrimidylaminobenzamides of formula (I) wherein the radicals have the meanings as defined herein,or of a pharmaceutically acceptable salt thereof for the manufacture of pharmaceutical compositions for use in the treatment of fibrosis, to the use of a pyrimidylaminobenzamides of formula (I) or pharmaceutically acceptable salt thereof in the treatment of fibrosis, to a method of treating warm-blooded animals including humans suffering from fibrosis by administering to a said animal in need of such treatment an effective dose of a pyrimidyl- aminobenzamide of formula I or a pharmaceutically acceptable salt thereof, and to combinationscomprising(a) at least one pyrimidylaminobenzamides of formula (I) as and (b) at least one compound selected form AT1-receptor antagonists and ACE inhibitors and the use of such combinations in the treatment of fibrosis, in particular hepatic fibrosis.
TNP2010000600A2009-07-142010-12-24Use of pyrimidylamidnobenzamide derivatives for the treatment of fibrosis
TN2010000600A1
(en)