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Priority claimed from PCT/JP2009/054007external-prioritypatent/WO2009107850A2/en
Application filed by Takeda PharmaceuticalfiledCriticalTakeda Pharmaceutical
Publication of TN2010000381A1publicationCriticalpatent/TN2010000381A1/en
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The present invention provides a compound having a superior Smo inhibitory activity and lower toxicity, which is sufficiently satisfactory as a pharmaceutical product.The present invention provides a compound represented by the formula (1) wherein ring A is 5- to 7-membered ring optionally having substituent(s), where substituents are optionally bonded to each other to form a ring; X is O,S or NR1 (R1 is a hydrogen atom or a hydrocarbon group optionally having substituent(s)); R2 is carbamoyl optionally having substituent(s); and R3 is hydroxy optionally having substituent(s), or a salt thereof.
TNP2010000381A2009-02-252010-08-19Fused heterocyclic derivative and use thereof
TN2010000381A1
(en)