TH97677B - SCD1-inhibiting organic compounds and their use - Google Patents
SCD1-inhibiting organic compounds and their useInfo
- Publication number
- TH97677B TH97677B TH701004055A TH0701004055A TH97677B TH 97677 B TH97677 B TH 97677B TH 701004055 A TH701004055 A TH 701004055A TH 0701004055 A TH0701004055 A TH 0701004055A TH 97677 B TH97677 B TH 97677B
- Authority
- TH
- Thailand
- Prior art keywords
- scd1
- organic compounds
- inhibiting organic
- derivatives
- activity
- Prior art date
Links
- 101100041816 Homo sapiens SCD gene Proteins 0.000 title 1
- 101150097713 SCD1 gene Proteins 0.000 title 1
- 102100028897 Stearoyl-CoA desaturase Human genes 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 150000002894 organic compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000000470 constituent Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- SIARJEKBADXQJG-LFZQUHGESA-N stearoyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCCCCCCCCCCCCCCC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 SIARJEKBADXQJG-LFZQUHGESA-N 0.000 abstract 1
Abstract
การประดิษฐ์ครั้งนี้จะจัดหาอนุพันธ์เฮทเทอโรไซคลิกที่ปรับควบคุมฤทธิ์ของ สเตียโรอิล-CoA ดีแซททูเรส วิธีการของการใช้อนุพันธ์ดังกล่าวเพื่อปรับควบคุมฤทธิ์ของสเตียโรอิล- CoA ดีแซททูเรส และองค์ประกอบเชิงเภสัชกรรมซึ่งประกอบรวมด้วยอนุพันธ์ดังกล่าวจะถูกรวมไว้ ด้วย This invention will provide a heterocyclic derivative that modulates the activity of A method of using such derivatives to regulate the activity of stearyl-CoA decaturase and pharmaceutical constituents comprising their derivatives. Such will be included.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH97677B true TH97677B (en) | 2009-08-13 |
| TH97677A TH97677A (en) | 2009-08-13 |
Family
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