TH97382B - 3H-imidazo [4,5-b] Pyridine derivative, process for the preparation of such substances, pharmaceutical constituents, intermediate compounds. And the use of such substances in the prevention and / or treatment of manic disorder, Alzheimer's disease, Parkinson's disease, Parkinson's disease fronotemporal disease, Complex Parkinson's, Guam-induced ED, HIV-induced mental illness, etc. and how to prevent it. - Google Patents

3H-imidazo [4,5-b] Pyridine derivative, process for the preparation of such substances, pharmaceutical constituents, intermediate compounds. And the use of such substances in the prevention and / or treatment of manic disorder, Alzheimer's disease, Parkinson's disease, Parkinson's disease fronotemporal disease, Complex Parkinson's, Guam-induced ED, HIV-induced mental illness, etc. and how to prevent it.

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Publication number
TH97382B
TH97382B TH601004862A TH0601004862A TH97382B TH 97382 B TH97382 B TH 97382B TH 601004862 A TH601004862 A TH 601004862A TH 0601004862 A TH0601004862 A TH 0601004862A TH 97382 B TH97382 B TH 97382B
Authority
TH
Thailand
Prior art keywords
disease
parkinson
substances
induced
preparation
Prior art date
Application number
TH601004862A
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Thai (th)
Other versions
TH97382A (en
Inventor
นายเออร์แวน อาร์เชล นายโทเบียส เรน นายดีดีเอร์ ร็อตติคซี่ นายเพอ ไอ อาร์วิดส์สัน นาง เฮเลน่า กีแบ็ค นางเจเรมี่ เบอร์โรว์ส นายปีเตอร์ โซเดอร์มัน
Original Assignee
แอสตราเซเนกา เอบี
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Publication date
Application filed by แอสตราเซเนกา เอบี filed Critical แอสตราเซเนกา เอบี
Publication of TH97382A publication Critical patent/TH97382A/en
Publication of TH97382B publication Critical patent/TH97382B/en

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Abstract

การประดิษฐ์นี้เกี่ยวกับสารประกอบชนิดใหม่สูตร I (สูตรเคมี) I ในรูปเบสเสรีหรือเกลือ, ซอลเวทหรือซอลเวทของเกลือของสารเหล่านั้นที่ยอมรับได้ทางเภสัชกรรม, กรรมวิธีสำหรับการเตรียมสารเหล่านั้น และสารขั้นกลางชนิดใหม่ที่ใช้ในที่นั้น สูตรผสมทาง เภสัชกรรมซึ่งมีสารประกอบที่มีความว่องไวทางการรักษาดังกล่าวและเกี่ยวกับการใช้สารประกอบ ที่มีความว่องไวดังกล่าวในการักษา This invention relates to a new compound, formula I (chemical formula) I in the form of free bases or salts, salts or salts of those salts that are pharmacologically acceptable, methods for their preparation. And a new intermediate of the compound used there, a pharmaceutical formulation containing such therapeutic-agile compounds and in connection with their use. With such agility in keeping

Claims (1)

1. สารประกอบสูตร I (สูตรเคมี) I ซึ่ง: R1 เลือกจากไฮโดรเจน, เฮโล, CN, NO2, C1-3แอลคิล, C1-3เฮโลแอลคิล, ORa, SO2NRbRc, C(O) NRbRc, CH2NRbRc, CH2ORh, SO2Ri และ C(O)Rj; R2 และ R4 เป็นอิสระต่อกันเลือกจากไฮโดรเจน, เฮโล, CN, NO2, C1-3แอลคิล, C1-3เฮโแอลคิล, ORa, SO2NRbRc, C(O) NRbRc, CH2NRbRc, CH2ORh, SO2Ri และ C(O)Rj; R3 และ R5 เป็นอิสระต่อกันเลือกจากไฮโดรเจน, C1-3แอลคิลและ C1-3เฮโล:1. Compound formula I (chemical formula) I, in which: R1 is selected from hydrogen, halo, CN, NO2, C1-3 alkyl, C1-3 halalkyl, ORa, SO2NRbRc, C (O) NRbRc, CH2NRbRc. , CH2ORh, SO2Ri and C (O) Rj; R2 and R4 are independent of each other, selected from hydrogen, halo, CN, NO2, C1-3 alkyl, C1-3 hemalkyl, ORa, SO2NRbRc, C (O) NRbRc, CH2NRbRc, CH2ORh, SO2Ri, and C (O) Rj; R3 and R5 are independent of hydrogen, C1-3 alkyl and C1-3 halo:
TH601004862A 2006-10-02 3H-imidazo [4,5-b] Pyridine derivative, process for the preparation of such substances, pharmaceutical constituents, intermediate compounds. And the use of such substances in the prevention and / or treatment of manic disorder, Alzheimer's disease, Parkinson's disease, Parkinson's disease fronotemporal disease, Complex Parkinson's, Guam-induced ED, HIV-induced mental illness, etc. and how to prevent it. TH97382B (en)

Publications (2)

Publication Number Publication Date
TH97382A TH97382A (en) 2009-08-06
TH97382B true TH97382B (en) 2009-08-06

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