TH96088B - CRYSTALLINE NEMORUBICIN HYDROCHLORIDE - Google Patents
CRYSTALLINE NEMORUBICIN HYDROCHLORIDEInfo
- Publication number
- TH96088B TH96088B TH701003362A TH0701003362A TH96088B TH 96088 B TH96088 B TH 96088B TH 701003362 A TH701003362 A TH 701003362A TH 0701003362 A TH0701003362 A TH 0701003362A TH 96088 B TH96088 B TH 96088B
- Authority
- TH
- Thailand
- Prior art keywords
- crystalline
- hydrochloride
- nemorubicin hydrochloride
- preparing
- crystalline nemorubicin
- Prior art date
Links
- DSXDXWLGVADASF-QQFKZXDBSA-N (7s,9s)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-7-[(2r,4s,5s,6s)-5-hydroxy-4-[(2s)-2-methoxymorpholin-4-yl]-6-methyloxan-2-yl]oxy-4-methoxy-8,10-dihydro-7h-tetracene-5,12-dione;hydrochloride Chemical compound Cl.C1CO[C@H](OC)CN1[C@@H]1[C@H](O)[C@H](C)O[C@@H](O[C@@H]2C3=C(O)C=4C(=O)C5=C(OC)C=CC=C5C(=O)C=4C(O)=C3C[C@](O)(C2)C(=O)CO)C1 DSXDXWLGVADASF-QQFKZXDBSA-N 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- NSNHWTBQMQIDCF-UHFFFAOYSA-N dihydrate;hydrochloride Chemical compound O.O.Cl NSNHWTBQMQIDCF-UHFFFAOYSA-N 0.000 claims 1
- 150000004683 dihydrates Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- JLFVIEQMRKMAIT-UHFFFAOYSA-N ac1l9mnz Chemical compound O.O.O JLFVIEQMRKMAIT-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000005426 pharmaceutical component Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกียวข้องกับรูปแบบโพลีมอร์ฟที่ผลึกชนิดใหม่ของนีโมรูบิซิน ไฮโดรไรด์ ไดไฮเดรท ที่จะเป็นประโยชน์สำหรับการเตรียมองค์ประกอบทางเภสัชกรรม สำหรับ การบำบัดรักษาของเนื้องอก กระบวนการสำหรับเตรียมรูปแบบโพลีมอร์ฟชนิดใหม่นี้ ที่ถูกรียกชื่อว่ารูปแบบ A จะอยู้ภายในขอบเขตของการประดิษฐ์นี้ The invention relates to a new crystalline polymorphic form of nemorubisin hydroxide dihydrate that will be useful for preparing a pharmaceutical component for the treatment of tumors. The process for preparing this new polymorph form Which was called the A pattern would be within the scope of this invention.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH96088B true TH96088B (en) | 2009-06-18 |
| TH96088A TH96088A (en) | 2009-06-18 |
Family
ID=
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