TH94278B - Pyrimidine derivatives linked to heteroalkyl. - Google Patents
Pyrimidine derivatives linked to heteroalkyl.Info
- Publication number
- TH94278B TH94278B TH601005661A TH0601005661A TH94278B TH 94278 B TH94278 B TH 94278B TH 601005661 A TH601005661 A TH 601005661A TH 0601005661 A TH0601005661 A TH 0601005661A TH 94278 B TH94278 B TH 94278B
- Authority
- TH
- Thailand
- Prior art keywords
- compounds
- heteroalkyl
- alkyl
- cell proliferation
- pyrimidine derivatives
- Prior art date
Links
- 125000004404 heteroalkyl group Chemical group 0.000 title claims abstract 3
- 150000003230 pyrimidines Chemical class 0.000 title abstract 2
- 229940083082 Pyrimidine derivatives acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 5
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000005842 heteroatoms Chemical group 0.000 claims 3
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- -1 cycloalkylkyl Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract 3
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000030951 Phosphotransferases Human genes 0.000 abstract 1
- 108091000081 Phosphotransferases Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drugs Drugs 0.000 abstract 1
- 239000008196 pharmacological composition Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวกับสารประกอบพิริมิดีน ที่มีประโยชน์เป็นสารต้านการเพิ่มจำนวนเซลล์ โดยเฉพาะเจาะจงยิ่งขึ้น, การประดิษฐ์นี้เกี่ยวกับสารประกอบที่เชื่อมกับเฮเทโรแอลคิลและสาร ประกอบพิริมิดีนที่ถูกแทนที่, วิธีการเตรียมมัน, องค์ประกอบเชิงเภสัชวิทยาที่มีสารประกอบเหล่านี้ และการใช้สารประกอบเหล่านี้ในการบำบัดความผิดปกติเหตุการเพิ่มจำนวนเซลล์ สารประกอบเหล่า นี้อาจจะมีประโยชน์เป็นยาสำหรับการบำบัดความผิดปกติเหตุการเพิ่มจำนวนเซลล์มากมาย ซึ่งรวมถึง เนื้องอก และมะเร็ง รวมทั้งสภาวะหรือความผิดปกติอื่นที่เกิดร่วมกับไคเนส This invention is about pyrimidine compounds. Useful as an anti-cell proliferation agent More specifically, this invention deals with heteroalkyl-binding compounds and Contains replaced pyimidine, method of preparation, pharmacological composition with these compounds. And the use of these compounds in the treatment of cell proliferation disorders. These compounds This may be useful as a drug for the treatment of many cell proliferation disorders, including tumors and cancers, as well as other kinase conditions or disorders.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH94278B true TH94278B (en) | 2009-03-13 |
| TH94278A TH94278A (en) | 2009-03-13 |
Family
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