TH92483B - New vinilogus acid derivatives - Google Patents
New vinilogus acid derivativesInfo
- Publication number
- TH92483B TH92483B TH601005969A TH0601005969A TH92483B TH 92483 B TH92483 B TH 92483B TH 601005969 A TH601005969 A TH 601005969A TH 0601005969 A TH0601005969 A TH 0601005969A TH 92483 B TH92483 B TH 92483B
- Authority
- TH
- Thailand
- Prior art keywords
- vinilogus
- new
- acid derivatives
- alkyl
- formula
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- -1 nitro, cyan, amino Chemical group 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical group 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Abstract
การประดิษฐ์ได้รับการเกี่ยวพันกับอนุพันธ์ของกรดไวนิโลกัสที่มีสูตร (I) (สูตรเคมี) (I) ในที่ซึ่ง A และ R1 เป็นดังที่ได้รับการให้คำจำกัดความในการพรรณนาและในข้อถือสิทธิ รวมทั้งเกลือของสิ่งเหล่านี้ที่สามารถยอมรับได้ทางสรีรวิทยา สารประกอบเหล่านี้ยับยั้งไคเมสและ สามารถได้รับการใช้ในฐานะเป็นเภสัชภัณฑ์ The invention is associated with a vinilocic acid derivative having the formula (I) (chemical formula) (I), where A and R1 are, as they have been defined in the description and in the claim. As well as the salts of these that are physiologically acceptable These compounds inhibit chimase and Can be used as a pharmaceutical
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH92483A TH92483A (en) | 2008-11-28 |
TH92483B true TH92483B (en) | 2008-11-28 |
Family
ID=
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