TH9065B - Glycopeptide antibiotic preparations - Google Patents
Glycopeptide antibiotic preparationsInfo
- Publication number
- TH9065B TH9065B TH8701000610A TH8701000610A TH9065B TH 9065 B TH9065 B TH 9065B TH 8701000610 A TH8701000610 A TH 8701000610A TH 8701000610 A TH8701000610 A TH 8701000610A TH 9065 B TH9065 B TH 9065B
- Authority
- TH
- Thailand
- Prior art keywords
- nrrl
- antibiotics
- process according
- antibiotic
- glycopeptide antibiotic
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims 3
- 239000003910 polypeptide antibiotic agent Substances 0.000 title abstract 2
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 claims abstract 3
- 241001430312 Amycolatopsis orientalis Species 0.000 claims abstract 2
- 239000003242 anti bacterial agent Substances 0.000 claims 5
- 229940088710 antibiotic agent Drugs 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- MYPYJXKWCTUITO-KIIOPKALSA-N chembl3301825 Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)C(O)[C@H](C)O1 MYPYJXKWCTUITO-KIIOPKALSA-N 0.000 abstract 1
Abstract
ยาปฏิชีวนะไกลโคเพบไทด์ชนิดใหม่ A82846 ซึ่งประกอบด้วยA82846A, A82846B และ A82846C สามารถผลิตได้จาก Nocardia orientalis สายพันธุ์ NRRL 18098, NRRL 18099 และNRRL 18100 ยาปฏิชีวนะ A82846 มีฤทธิ์ต่อต้านแบคทีเรียชนิดกรัมบวกเท่าเทียมกับแวนโคมัยซิน A novel glycopeptide antibiotic, A82846, consisting of A82846A, A82846B and A82846C, can be produced from Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The antibiotic A82846 is active against gram-positive bacteria on an equal footing with vancomycin.
Claims (5)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH9958A TH9958A (en) | 1991-12-01 |
| TH9065B true TH9065B (en) | 1999-08-05 |
Family
ID=
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