TH90120B - Heterocycle containing 1,4-dihydropyridine is connected, the process of the preparation of such substances, use and mixtures containing such substances. - Google Patents
Heterocycle containing 1,4-dihydropyridine is connected, the process of the preparation of such substances, use and mixtures containing such substances.Info
- Publication number
- TH90120B TH90120B TH601003356A TH0601003356A TH90120B TH 90120 B TH90120 B TH 90120B TH 601003356 A TH601003356 A TH 601003356A TH 0601003356 A TH0601003356 A TH 0601003356A TH 90120 B TH90120 B TH 90120B
- Authority
- TH
- Thailand
- Prior art keywords
- substances
- dihydropyridine
- preparation
- heterocycle
- mixtures containing
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 6
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 3
- YNGDWRXWKFWCJY-UHFFFAOYSA-N dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 230000000875 corresponding Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- HFBYLYCMISIEMM-FFHNEAJVSA-N (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol;phosphoric acid Chemical compound OP(O)(O)=O.C([C@H]1[C@H](N(CC[C@@]112)C)C3)C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC HFBYLYCMISIEMM-FFHNEAJVSA-N 0.000 abstract 1
- 102000030951 Phosphotransferases Human genes 0.000 abstract 1
- 108091000081 Phosphotransferases Proteins 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Abstract
เฮเทอโรไซเคิลที่มี 1,4-ไดไฮโดรไพรริดีนเชื่อมต่อกัน,กระบวนการในการเตรียมสารดังกล่าว, การใช้ และสารผสมที่มีสารดังกล่าว การประดิษฐ์นี้เกี่ยวข้องกับเฮเทอร์โรไซเคิลที่มีไดไฮโดร ไพริดีนที่เชื่อมต่อกันซึ่งถูกแทนที่ซึ่งมีประโยชน์สำหรับการรักษาโรคมะเร็ง โดยเฉพาะอย่างยิ่ง สำหรับป้องกันไม่ให้เซลล์มะเร็งแบ่งตัว สารประกอบเหล่านี้ทำหน้าที่เป็นสารยับยั้งออโรรา A และ/หรือ B ไคเนส (สูตรเคมี) Heterocycle containing 1,4-dihydropyridine is connected, the process of the preparation of such substances, use and mixtures containing such substances. This invention relates to heterocycle with dihydro. Substituted conjugated pyridine useful for cancer treatment Especially For preventing cancer cells from dividing These compounds act as inhibitors for Aurora A and / or B kinase (chemical formula).
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH90120B true TH90120B (en) | 2008-06-20 |
| TH90120A TH90120A (en) | 2008-06-20 |
Family
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