TH88751B - N-phenylphenyl azetamate as an NNRT inhibitor - Google Patents
N-phenylphenyl azetamate as an NNRT inhibitorInfo
- Publication number
- TH88751B TH88751B TH601005109A TH0601005109A TH88751B TH 88751 B TH88751 B TH 88751B TH 601005109 A TH601005109 A TH 601005109A TH 0601005109 A TH0601005109 A TH 0601005109A TH 88751 B TH88751 B TH 88751B
- Authority
- TH
- Thailand
- Prior art keywords
- substances
- alkyl
- azetamate
- phenylphenyl
- hiv infection
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 7
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical group 0.000 claims 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 241001024304 Mino Species 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 229910052731 fluorine Chemical group 0.000 claims 1
- 239000011737 fluorine Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 208000031886 HIV Infections Diseases 0.000 abstract 3
- 208000037357 HIV infectious disease Diseases 0.000 abstract 3
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 3
- 208000030507 AIDS Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้ทำให้มีสารที่มีสารที่มีประโยชน์ในการรักษาการติดเชื้อ HIV หรือ ป้องกันการติดเชื้อ HIV หรือรักษาโรค AIDS หรือ ARC สารของการประดิษฐ์นี้ได้แก่ สารสูตร I ซึ่ง R1, R2, R3, R4, R5, และ X มีความหมายดังที่กำหนดไว้ในคำขอรับสิทธิบัตรนี้ สิ่งที่ได้รับ การเปิดเผยไว้ด้วยในการประดิษฐ์นี้คือ วิธีการรักษาการติดเชื้อ HIV ด้วยสารดังที่กำหนดไว้ใน คำขอรับสิทธิบัตรนี้ และสารผสมทางเภสัชกรรมที่มีสารดังกล่าวเป็นส่วนประกอบ (สูตรเคมี) (I) This invention contains substances containing substances useful in the treatment of HIV infection or to prevent HIV infection or to treat AIDS or ARC. And X has the meaning defined in this patent application. What has been Also disclosed in this invention is Methods for treating HIV infection with substances as defined in This patent application And pharmaceutical mixtures containing such substances (chemical formula) (I)
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH88751B true TH88751B (en) | 2008-02-29 |
| TH88751A TH88751A (en) | 2008-02-29 |
Family
ID=
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